About The Study: This study found persistent patterns of potentially aggressive care, but low uptake of supportive care, among Medicare decedents with advanced cancer. A multifaceted approach targeting patient-, physician-, and system-level factors associated with potentially aggressive care is imperative for improving quality of care at the end of life. Corresponding Author: To contact the corresponding author, Youngmin Kwon, PhD, email youngmin.kwon@vumc.org. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamahealthforum.2024.5436) Editor’s Note: Please see the article ...

About The Study: In this systematic review and dose-response meta-analysis, a daily 1-hour increment in digital screen time was associated with 21% higher odds of myopia (nearsightedness) and the dose-response pattern exhibited a sigmoidal shape, indicating a potential safety threshold of less than 1 hour per day of exposure, with an increase in odds up to 4 hours. These findings can offer guidance to clinicians and researchers regarding myopia risk. Corresponding Author: To contact the corresponding author, Young Kook Kim, PhD, email md092@naver.com. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.60026) Editor’s ...

About The Study: In this cohort study using a target trial emulation, a higher proportion of weight loss after initiating anti-obesity medications within 1 year was associated with a lower risk of 5-year and 10-year revision among patients with obesity undergoing joint replacement. These results suggest that anti-obesity medication use, with relatively safe and sustainable weight loss, may be an effective strategy for improving implant survivorship of hip and knee replacements in the obese population. Corresponding Author: To ...

Despite considerable efforts to improve the quality of end-of-life care in the United States, a new retrospective study led by American Cancer Society (ACS) researchers revealed that close to half of patients with advanced cancer received potentially aggressive care at the end-of-life at the expense of supportive care. The findings are out today in the Journal of the American Medical Association (JAMA) Health Forum. “Even though clinicians and professional healthcare organizations have recommended early integration of supportive and ...

Investigators at Mass General Brigham have developed a tool that can identify older adults at increased risk of emergency healthcare needs, rehospitalization or death. The tool measured patient frailty, an aging-related syndrome, by integrating the health records of more than 500,000 individuals collected across multiple hospitals at Mass General Brigham. These findings, published in Journal of the American Geriatric Society, could help clinicians care for high-risk patients even without the availability of comprehensive primary care records. “Frailty ...

COLUMBUS, Ohio – The combination of prescribed central nervous system stimulants, such as drugs that relieve ADHD symptoms, with prescribed opioid medications is associated with a pattern of escalating opioid intake, a new study has found. The analysis of health insurance claims data from almost 3 million U.S. patients investigated prescribed stimulants’ impact on prescription opioid use over 10 years, looking for origins of the so-called “twin epidemic” of combining the two classes of drugs, which can increase the risk for overdose deaths. “Combining the two drugs is associated ...

 As the severity of climate change and carbon emissions becomes a global concern, technologies to convert carbon dioxide (CO₂) into resources such as chemical fuels and compounds are urgently needed. Dr. Dahee Park’s research team from the Nano Materials Research Division at the Korea Institute of Materials Science (KIMS), has collaborated with Professor Jeong-Young Park’s team from the Department of Chemistry at KAIST to develop a catalyst technology that significantly enhances the efficiency of carbon dioxide (CO2) conversion.  Conventional ...

Mechanochemistry using a ball mill demonstrates versatility for generating academically and industrially significant organolithium compounds. Organolithium compounds, molecules containing a carbon–lithium bond, are excellent precursors for building new carbon–carbon and other carbon–heteroatom bonds. They are widely utilized in both academia and industry for their applications in polymer synthesis, pharmaceuticals, and general organic synthesis. A conventional method for generating organolithiums is done ...

Rubidium could be the next key player in oxide-ion conductors. Researchers at Institute of Science Tokyo have discovered a rare rubidium (Rb)-containing oxide-ion conductor, Rb₅BiMo₄O₁₆, with exceptionally high conductivity. Identified through computational screening and experiments, its superior performance stems from low activation energy and structural features like large free volume and tetrahedral motion. Its stability under various conditions offers a promising direction for solid oxide fuel cells and clean energy technologies. Oxide-ion ...

Houston, we have a problem. The ‘Space City’ boasts 50 buildings over 150 meters tall. These were designed to withstand hurricanes, to which Texas is prone. But on May 16th, 2024, a derecho – a wide, long-lived windstorm associated with rapidly moving showers or thunderstorms – managed to cause unexpected damage to many of the tall buildings downtown. The socio-economic impact was significant, due to traffic disruptions, businesses temporarily closing, and the need for repairs. Why ...

Optical atomic clocks can increase the precision of time and geographic position a thousandfold in our mobile phones, computers, and GPS systems. However, they are currently too large and complex to be widely used in society. Now, a research team from Purdue University, USA, and Chalmers University of Technology, Sweden, has developed a technology that, with the help of on-chip microcombs, could make ultra-precise optical atomic clock systems significantly smaller and more accessible – with significant benefits for navigation, autonomous vehicles, and geo-data monitoring. Today, our mobile phones, computers, ...

Scientists have now mapped the forces acting inside a proton, showing in unprecedented detail how quarks—the tiny particles within—respond when hit by high-energy photons. The international team includes experts from the University of Adelaide who are exploring the structure of sub-atomic matter to try and provide further insight into the forces that underpin the natural world. “We have used a powerful computational technique called lattice quantum chromodynamics to map the forces acting inside ...

Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through UCL Institute of Ophthalmology and Moorfields Eye Hospital, with the support of MeiraGTx. The children were born with a severe impairment to their sight due to a rare genetic deficiency that affects the AIPL1 gene. The condition, a form of retinal dystrophy, means those affected are born with only sufficient sight to distinguish between light and darkness. The gene defect causes ...

Workplace bullying affects not only the employee’s sleep but their partner’s too, according to new research published today. Exposure to bullying by superiors and/or colleagues has been linked to a variety of negative health outcomes, such as sleep problems. Now research by the University of East Anglia (UEA) in the UK, and Complutense University of Madrid and Seville University in Spain, sheds light on the short-term consequences of workplace bullying on various indicators of sleep. These include waking up too early (sleep severity), interference with daily life (sleep impact) and dissatisfaction with own sleep (sleep satisfaction). Writing in ...

A new study led by the University of Cambridge has revealed that as our springs and summers get hotter and drier, the UK wildfire season is being stretched and intensified. More fires, taking hold over more months of the year, are causing more carbon to be released into the atmosphere as carbon dioxide. Fires on peatlands, which are carbon-rich, can almost double global fire-driven carbon emissions. Researchers found that despite accounting for only a quarter of the total UK land area that burns each year, dwarfed by moor and heathland, peatland fires have caused up to 90% of annual UK fire-driven carbon emissions since 2001 – with emissions ...

A new USC study reveals a dramatic surge in building collapses in the ancient Egyptian port city of Alexandria, directly linked to rising sea levels and seawater intrusion. Once a rare occurrence, building collapses in Alexandria — one of the world’s oldest cities, often called the “bride of the Mediterranean” for its beauty — have accelerated from approximately one per year to an alarming 40 per year over the past decade, the researchers found. “The true cost of this loss extends far beyond bricks and mortar. We are witnessing the gradual disappearance of historic coastal ...

DALLAS, Feb. 20, 2025 — The American Heart Association, a global force devoted to changing the future of health for all, and Walgreens, one of the nation's largest community-based pharmacies, are stepping up to support the Association’s Nation of Lifesavers™ movement nationwide. Walgreens will lead efforts in its stores and communities to raise awareness of CPR and drive CPR training and consumer support of the Association’s ...

One of nature’s most disliked creatures may very well unlock a breakthrough in disaster response. A multidisciplinary Purdue University research team is recreating mosquito antennae to better study their sensitivity to vibrations. Should the research prove fruitful, it could lead to improvements in monitoring and detecting natural disasters such as earthquakes and tsunamis. Research groups under Purdue professors Pablo Zavattieri and Ximena Bernal conducted this work, which is published in the journal Acta Biomaterialia. “We’re still in the early stages but we’re ...

Fetal acetaminophen exposure increases the likelihood that a child will develop attention-deficit/hyperactivity disorder (ADHD), according to a study published Feb. 6 in Nature Mental Health.   Prior research shows that upward of 70% of pregnant women use acetaminophen during pregnancy to control pain or reduce fever. The drug, which is the active ingredient of many pain-relief medications, is one of the few considered safe to take during pregnancy by the U.S. Food and Drug ...

‘The most common number of therapy sessions people access is one’ Common in other countries but not in the U.S., single-session interventions are designed to treat patients in just one meeting Lab at Northwestern offers digital single-session interventions for youth in nine languages CHICAGO --- Seeking mental health help is a significant step, but that first intake session can often feel more like paperwork than progress, and a significant proportion of people “drop out” or never return for a second visit, previous research has shown.  “The most common number of sessions ...

A research team led by Rumi Chunara - an NYU associate professor with appointments in both the Tandon School of Engineering and the School of Global Public Health –  has unveiled a new artificial intelligence (AI) system that uses satellite imagery to track urban green spaces more accurately than prior methods, critical to ensuring healthy cities. To validate their approach, the researchers tested the system in Karachi, Pakistan's largest city where several team members are based. Karachi proved an ideal test case with its mix of dense urban areas and varying vegetation conditions. Accepted for publication by the ACM Journal on Computing and Sustainable Societies, ...

The International Society for Stem Cell Research (ISSCR) is honoring Gordon Keller, Ph.D., with this year’s ISSCR Achievement Award. Dr. Keller is the Director of the McEwen Stem Cell Institute at the University Health Network (UHN) in Toronto, Canada. He will present his research at the ISSCR 2025 Annual Meeting taking place in Hong Kong 11-14 June 2025. “Gordon Keller's groundbreaking work in regenerative medicine has illuminated the path to transforming human health,” said Andrea Ditadi, Group Leader, San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), Italy, who led the nomination of Dr. Keller. “From ...

The International Society for Stem Cell Research (ISSCR) is honoring Yonatan Stelzer, Ph.D. with the 2025 ISSCR Outstanding Young Investigator Award. Dr. Selzer is an associate professor in the Department of Molecular Cell Biology at the Weizmann Institute of Science, Israel. The award recognizes the exceptional achievements of an investigator in the early part of his or her independent career in stem cell research. Dr. Stelzer will present his work at the ISSCR 2025 Annual Meeting taking place in Hong Kong 11-14 June 2025. “Yonatan Stelzer’s innovative approach to real-time, single-cell ...

U.S. outpatient prescriptions for hydroxychloroquine and ivermectin increased 2- to 10-fold above pre-pandemic rates, respectively, to treat COVID-19, despite strong evidence disproving their effectiveness, new UCLA-led research shows. Nearly three million COVID-related prescriptions were issued in the three and a half years between January 30, 2020 and June 30, 2023, totaling $272 million in estimated spending. Usage was three times higher among adults aged 65 and older compared with those aged 18 to 64. Ivermectin use in particular was higher among people living in the most socially vulnerable neighborhoods and markedly higher in the Southern ...

Respiratory diseases are a challenging problem to treat. Inhalable medicines are a promising solution that depend on the ability to deliver tiny particles known as aerosols to the correct location in the lungs at the correct dosage.  How effectively this works can get complicated, depending on the drug, delivery method and patient. This is because it is difficult to predict just how much medicine gets in and where it goes in the lung. Similar challenges exist when thinking about measuring an ...