Reversals in the decline of heart failure mortality in the US
2024-04-24
About The Study: This analysis shows that declines in heart failure-related mortality from 1999 to 2012 have been entirely undone by reversals from 2012 to 2021, meaning that contemporary heart failure mortality rates are higher than in 1999. The origins of these reversals preceded the COVID-19 pandemic, although the larger increases in 2020 to 2021 indicate that the pandemic may have accelerated them due to limitations to health care access and possible cardiac involvement.
Authors: Marat Fudim, M.D., M.H.S., of Duke University in Durham, North Carolina, is the ...
Recreational marijuana laws and teen marijuana use, 1993-2021
2024-04-24
About The Study: In this repeated cross-sectional study, there was no evidence that recreational marijuana laws were associated with encouraging youth marijuana use, based on both the logistic regression and interaction-weighted models.
Authors: D. Mark Anderson, Ph.D., of Montana State University in Bozeman, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(10.1001/jamapsychiatry.2024.0698)
Editor’s Note: Please see ...
Manchester scientists found novel one-dimensional superconductor
2024-04-24
In a significant development in the field of superconductivity, researchers at The University of Manchester have successfully achieved robust superconductivity in high magnetic fields using a newly created one-dimensional (1D) system. This breakthrough offers a promising pathway to achieving superconductivity in the quantum Hall regime, a longstanding challenge in condensed matter physics.
Superconductivity, the ability of certain materials to conduct electricity with zero resistance, holds profound potential for advancements of quantum technologies. However, achieving superconductivity in the quantum Hall regime, characterised by quantised electrical conductance, has proven to be a mighty ...
Tumor cells evade the immune system early on: Newly discovered mechanism could significantly improve cancer immunotherapies
2024-04-24
Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München (LMU) Hospital have now uncovered for the first time how this exactly happens. The study in the journal Nature provides rationales for new cancer immunotherapies and could make existing treatments more effective. A second paper in Nature confirms the findings.
In cancer, tumors often impair the body's immune response. For example, they can prevent immune cells from perceiving cancer cells as a threat or render them inactive. Immunotherapies aim ...
Children with skin diseases suffer stigma, bullying and depression
2024-04-24
· 73% of children with skin disease experience stigma and poor quality of life
· ‘Chronic skin conditions can be tremendously life-altering’
· Shame during childhood can affect them throughout their lives, dermatologist says
CHICAGO --- The majority of children and teens with chronic skin diseases such as acne, eczema, psoriasis, alopecia areata (hair loss) and vitiligo (pigment loss) feel stigmatized by peers for their condition and are sometimes bullied, reports a new Northwestern Medicine study. As a result, these children have a ...
A novel universal light-based technique to control valley polarization in bulk materials
2024-04-24
Electrons inside solid materials can only take certain values of energy. The allowed energy ranges are called “bands” and the space between them, the forbidden energies, are known as “band-gaps”. Both of them together constitute the “band structure” of the material, which is a unique characteristic of each specific material.
When physicists plot the band structure, they usually see that the resulting curves resemble mountains and valleys. In fact, the technical term for a local energy maximum or minimum in the bands is called a “valley”, and the field which studies and exploits how electrons in the material ...
Vast DNA tree of life for flowering plants revealed by global science team
2024-04-24
Images
The most up-to-date understanding of the flowering plant tree of life is presented in a new study published today in the journal Nature by an international team of 279 scientists, including three University of Michigan biologists.
Using 1.8 billion letters of genetic code from more than 9,500 species covering almost 8,000 known flowering plant genera (ca. 60%), this achievement sheds new light on the evolutionary history of flowering plants and their rise to ecological dominance on Earth.
Led by scientists at the Royal Botanic Gardens, Kew, the research team believes ...
Mini-colons revolutionize colorectal cancer research
2024-04-24
As our battle against cancer rages on, the quest for more sophisticated and realistic models to study tumor development has never been more critical. Until now, research has relied on animal models and simplified cell culture methods, which are valuable but cannot fully capture the complex interplay of factors involved in tumor development.
Even newer, more advanced models for studying cancer, such as organoids – tiny, lab-grown versions of organs – do not faithfully replicate the cell behaviors and tissue architectures seen in actual tumors.
This gap has significantly hindered our understanding ...
Lead-vacancy centers in diamond as building blocks for large-scale quantum networks
2024-04-24
Much like how electric circuits use components to control electronic signals, quantum networks rely on special components and nodes to transfer quantum information between different points, forming the foundation for building quantum systems. In the case of quantum networks, color centers in diamond, which are defects intentionally added to a diamond crystal, are crucial for generating and maintaining stable quantum states over long distances.
When stimulated by external light, these color centers in diamond emit photons carrying information about their internal electronic states, especially the spin states. The interaction between the emitted photons and the ...
JMIR Rehabilitation and Assistive Technologies announces theme issue on participatory methods in rehabilitation research
2024-04-24
JMIR Publications invites submissions to a new theme issue titled “Incorporating Participatory Methods in Developing, Implementing, and Evaluating Rehab Interventions and Assistive Technologies” in its premier, open access journal JMIR Rehabilitation and Assistive Technologies (JRAT).
JRAT is a peer-reviewed journal indexed in PubMed and PubMed Central, SCOPUS, DOAJ, Web of Science, Sherpa Romeo, and EBSCO and EBSCO Essentials. This theme issue aims to showcase research that actively engages patients, caregivers, and other stakeholders (knowledge users) ...
SwRI’s Dr. Marc Janssens recognized for role in establishing cone calorimeter fire testing
2024-04-24
SAN ANTONIO — April 24, 2024 — Southwest Research Institute’s Dr. Marc Janssens was named a “DiNenno Prize Laureate” for his role in the widespread adoption of the cone calorimeter, a fire-testing tool that accurately measures heat release and material flammability. The National Fire Protection Association® recognized the cone calorimeter with the 2024 Philip J. DiNenno Prize for its lasting impact on fire safety. Dr. Vytenis Babrauskas, a co-recipient of the prize, developed the cone ...
Modeling broader effects of wildfires in Siberia
2024-04-24
As wildfires in Siberia become more common, global climate modeling estimates significant impacts on climate, air quality, health, and economies in East Asia and across the northern hemisphere.
The global effects of increasing wildfires in Siberia have been modeled by researchers at Hokkaido University and colleagues at the University of Tokyo and Kyushu University. The results, published in the journal Earth’s Future, suggest significant and widespread effects on air quality, climate, health, and economics under the most extreme wildfire scenarios.
The authors performed global numerical simulation experiments to evaluate how the increased intensity of wildfires ...
Researchers find oldest undisputed evidence of Earth’s magnetic field
2024-04-24
A new study, led by the University of Oxford and MIT, has recovered a 3.7-billion-year-old record of Earth’s magnetic field, and found that it appears remarkably similar to the field surrounding Earth today. The findings have been published today in the Journal of Geophysical Research.
Without its magnetic field, life on Earth would not be possible since this shields us from harmful cosmic radiation and charged particles emitted by the Sun (the ‘solar wind’). But up to now, there has been no reliable date for when the modern magnetic field was first established.
In the new study, the researchers examined ...
Eric and Wendy Schmidt announce 2024 Schmidt Science Fellows
2024-04-24
Eric and Wendy Schmidt Announce 2024 Schmidt Science Fellows
32 exceptional early career researchers will tackle ambitious interdisciplinary science projects
The seventh cohort of the interdisciplinary program, an initiative of Schmidt Sciences, will advance research in areas ranging from healthcare and the environment to advanced materials and robotics
The 2024 Fellows, representing 17 nationalities from 26 nominating institutions across North America, Europe, and Asia, will also benefit from bespoke ...
Paclitaxel-induced immune dysfunction and activation of transcription factor AP-1 facilitate Hepatitis B virus replication
2024-04-24
Background and Aims
Hepatitis B virus (HBV) reactivation is commonly observed in individuals with chronic HBV infection undergoing antineoplastic drug therapy. Paclitaxel (PTX) treatment has been identified as a potential trigger for HBV reactivation. This study aimed to uncover the mechanisms of PTX-induced HBV reactivation in vitro and in vivo, which may inform new strategies for HBV antiviral treatment.
Methods
The impact of PTX on HBV replication was assessed through various methods including enzyme-linked immunosorbent assay, dual-luciferase reporter assay, quantitative ...
Single-walled carbon nanotubes doped with ‘nitrogen’ enhance the performance of secondary battery anode
2024-04-24
Dr. Han Joong Tark and student researcher Lee Do Geun at the Nano Hybrid Technology Research Center of Korea Electrotechnology Research Institute(KERI) have developed a new manufacturing technique for "silicon/nitrogen-doped carbon composite anode materials." These materials aim to enhance the capacity and stability of lithium-ion battery anodes.
Silicon, despite offering significantly higher energy density compared to graphite (a common anode material), suffers from a major drawback: it expands 3-4 times during charging and discharging, leading to performance degradation. To address this issue, researchers are blending ...
Pioneering the future of urban traffic: The revolutionary spatiotemporal-restricted a* algorithm
2024-04-24
As urban areas continue to grow, the demand for innovative solutions to alleviate traffic congestion and improve transportation efficiency has never been more urgent. A recent breakthrough study presented by researchers from the Shanghai Artificial Intelligence Laboratory as well as international research team introduces a cutting-edge approach to managing traffic at urban intersections using the spatiotemporal-restricted A* algorithm. This advanced method promises to transform how traffic is handled by optimizing the flow of both connected automated vehicles (CAVs) and human-driven vehicles (HVs) ...
First-ever combined heart pump and pig kidney transplant gives new hope to patient with terminal illness
2024-04-24
NEW YORK, NY, APRIL 24, 2024— Surgeons at NYU Langone Health performed the first-ever combined mechanical heart pump and gene-edited pig kidney transplant surgery in a 54-year-old woman with heart and kidney failure—a confluence of advances that showcase the possibility and hope of modern medicine.
Doctors performed this feat in two stages: first surgically implanting the heart pump days before embarking on the landmark transplant, which included a gene-edited pig kidney and the pig’s thymus gland to aid against rejection. Before the procedure, patient Lisa Pisano, a New Jersey ...
FAU receives grant to examine role of pet dogs on military adolescents
2024-04-24
Florida Atlantic University Christine E. Lynn College of Nursing’s Canines Providing Assistance to Wounded Warriors (C-P.A.W.W.) has received a new grant from the Human Animal Bond Research Institute (HABRI) for research that investigates the contribution of pet dog ownership to resilience and well-being in adolescent children of military families.
The grant was awarded to a team of researchers led by Laurie Martinez, Ph.D., an assistant professor, FAU College of Nursing; and co-led by Cheryl A. Krause-Parello, Ph.D., associate vice president for research, FAU Division of Research and a research professor in the College of Nursing.
This important study will provide ...
COVID-19 pandemic alters view that doctors are obligated to provide care
2024-04-24
DURHAM, N.C. – The unique circumstances arising from the COVID-19 pandemic altered a long-held convention that doctors provide care regardless of personal risk.
In a study assessing doctors’ tolerance for refusing care to COVID-19 patients, Duke Health researchers identified a growing acceptance to withhold care because of safety concerns.
“All the papers throughout history have shown that physicians broadly believed they should treat infectious disease patients,” said the study’s lead author, Braylee Grisel, a fourth-year student at Duke University ...
This salt battery harvests osmotic energy where the river meets the sea
2024-04-24
Estuaries — where freshwater rivers meet the salty sea — are great locations for birdwatching and kayaking. In these areas, waters containing different salt concentrations mix and may be sources of sustainable, “blue” osmotic energy. Researchers in ACS Energy Letters report creating a semipermeable membrane that harvests osmotic energy from salt gradients and converts it to electricity. The new design had an output power density more than two times higher than commercial membranes in lab demonstrations.
Osmotic energy can be generated anywhere salt gradients are ...
On the trail of deepfakes, Drexel researchers identify ‘fingerprints’ of AI-generated video
2024-04-24
In February, OpenAI released videos created by its generative artificial intelligence program Sora. The strikingly realistic content, produced via simple text prompts, is the latest breakthrough for companies demonstrating the capabilities of AI technology. It also raised concerns about generative AI’s potential to enable the creation of misleading and deceiving content on a massive scale. According to new research from Drexel University, current methods for detecting manipulated digital media will not be effective against AI-generated video; but a machine-learning approach could be the key to unmasking these synthetic creations.
In a paper accepted ...
Virtual reality can motivate people to donate to refugee crises regardless of politics
2024-04-24
PULLMAN, Wash. – Political conservatives who watched a documentary on Syrian refugees with a virtual reality headset had far more sympathy for the people depicted in the film than those who viewed the same film on a two-dimensional computer screen.
Higher sympathy levels among the conservatives who watched the VR version of the documentary, “Clouds over Sidra,” resulted in a greater willingness to donate to the crisis, according to a study on the research published in New Media & Society.
Liberal participants in the study reported high levels of sympathy and ...
Holographic displays offer a glimpse into an immersive future
2024-04-24
Setting the stage for a new era of immersive displays, researchers are one step closer to mixing the real and virtual worlds in an ordinary pair of eyeglasses using high-definition 3D holographic images, according to a study led by Princeton University researchers.
Holographic images have real depth because they are three dimensional, whereas monitors merely simulate depth on a 2D screen. Because we see in three dimensions, holographic images could be integrated seamlessly into our normal view of the everyday world.
The result is a virtual and augmented reality display that has the potential to be truly immersive, the kind where you can move your head ...
Novel Au-BiFeO3 nanostructures for efficient and sustainable degradation of pollutants
2024-04-24
The need for sustainable and environment-friendly solutions has accelerated the global demand for green and renewable technologies. In this regard, semiconductor photocatalysts have emerged as an attractive solution, owing to their potential in mitigating pollutants and harnessing solar energy efficiently. Photocatalysts are materials that initiate chemical reactions when exposed to light. Despite their progress, commonly used photocatalysts suffer from reduced photocatalytic activity and a narrow operation range within the visible ...
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