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Childhood factors associated with unnatural death through midadulthood

2024-02-23
About The Study: In this urban population-based cohort study of 2,180 participants, no modifiable risk factors of mortality at the level of the individual (e.g., depression or anxiety and substance use) or the family (e.g., household education level) were identified. However, the degree of neighborhood poverty in early childhood was significantly associated with death by unnatural causes (death due to unintentional injury, suicide, and homicide) in early adulthood, suggesting that economic policies are needed to advance health equity in relation to premature mortality.  Authors: Holly C. Wilcox, Ph.D., of the Johns Hopkins Bloomberg ...

Severe COVID-19 in vaccinated adults with hematologic cancers in the Veterans Health Administration

2024-02-23
About The Study: In this case-control study including 6,122 patients with hematologic cancers and SARS-CoV-2 infection, odds of severe COVID-19 remained high through mid-2022 despite vaccination, especially in patients requiring treatment.  Authors: Paul A. Monach, M.D., Ph.D., of the VA Boston Cooperative Studies Program in Boston, is the corresponding author.  To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jamanetworkopen.2024.0288) Editor’s Note: Please see the article for additional information, including other authors, author contributions ...

Recreational marijuana legalization and workplace injuries among younger workers

2024-02-23
About The Study: In this study, recreational marijuana laws that allow recreational marijuana sales were associated with a 10% increase in workplace injuries among individuals ages 20 to 34. The findings are consistent with the hypothesis that recreational marijuana impedes cognitive function and care among younger workers.  Authors: Joseph J. Sabia, Ph.D., of San Diego State University, is the corresponding author. To access the embargoed study: Visit our For The Media website at this ...

New study identifies 13 strategies for advancing racial and ethnic equity in the academic health sciences

2024-02-23
BOSTON - Amid continued debate over how to advance diversity and equity in higher education following the Supreme Court’s decision striking down affirmative action, researchers from Massachusetts General Hospital and Northeastern University today issued a “roadmap” of strategies to help academic health institutions maintain their commitments to racial and ethnic diversity among their students, staff, and faculty in academic health sciences. Their recommendations, published in JAMA Health Forum, outline 13 evidence-based strategies for increasing racial and ethnic equity in graduate-level health programs. “This ...

School focus on grades, test scores linked to violence against teachers

2024-02-23
COLUMBUS, Ohio – Violence against teachers is likely to be higher in schools that focus on grades and test scores than in schools that emphasize student learning, a new study has found. Researchers surveyed over 9,000 U.S. teachers shortly before and during the height of the COVID-19 pandemic about their perception of the instructional emphasis in their schools. Participants also reported whether they had been subjected to physical, verbal or property violence – by students, parents, colleagues and/or administrators. Results ...

Genetic signature may predict response to immunotherapy for non-small cell lung cancer

2024-02-23
A new study identified a set of 140 genes that may help predict enhanced disease-free survival in patients with non-small cell lung cancer (NSCLC) treated with a combination of immunotherapy and low-dose radiation. The results, published in Cell Reports Medicine on Feb. 23, suggested that this “gene signature” could be used to identify a subclass of lung tumors that is more likely to be eradicated by immunotherapies. Immunotherapy has saved countless lives but only 20 to 25 percent of patients respond to this treatment that activates a person’s ...

A study by the UMA and the University of California analyzes how lies affect economic decisions

A study by the UMA and the University of California analyzes how lies affect economic decisions
2024-02-23
Psychology and Economics come together in a recent line of research, led by Ismael Rodríguez-Lara, Professor at the University of Malaga, who studies how lies affect economic decisions. It is a study developed together with the Professor at the University of California (Santa Barbara, USA) Gary Charness, considered one of the most influential economists in the world within the experimental area, that has analyzed the way in which morality influences the degree of lying in certain economic situations. The results of this research have been published in the scientific journal Economics ...

Navigating the depths: Exploration in underwater navigation using acoustic beacons

Navigating the depths: Exploration in underwater navigation using acoustic beacons
2024-02-23
New exploration  in underwater navigation, a team from the Naval University of Engineering in Wuhan, China, has created novel algorithms that rectify inertial errors using sparse acoustic signals. This exploration offers novel method for the  issue of underwater navigation , where traditional satellite systems are ineffective due to their signals' inability to penetrate water effectively. The increasing demand for precise underwater Positioning, Navigation, and Timing (PNT) due to expanding marine exploration and activities highlights the limitations of traditional Global Satellite Navigation Systems (GNSS) ...

Shaping the future: A new technique for sorting micro-particles unveiled

Shaping the future: A new technique for sorting micro-particles unveiled
2024-02-23
Thanks to the rapid progress in tiny tech, we've been mainly using microfluidics to sort tiny particles by size. But now, there's a new way to sort them by shape, which could be a big deal for medical tests and chemistry. This study shows off a new method using sound waves to separate oddly shaped particles from round ones, without needing any labels. This breakthrough could lead to better ways to deliver drugs or diagnose diseases by offering a smarter approach to sort these tiny particles.  In the realm of microfluidics, separating micro-particles based solely on size has been the norm. However, distinguishing these particles ...

Mixed-dimensional transistors enable high-performance multifunctional electronic devices

Mixed-dimensional transistors enable high-performance multifunctional electronic devices
2024-02-23
Downscaling of electronic devices, such as transistors, has reached a plateau, posing challenges for semiconductor fabrication. However, a research team led by materials scientists from City University of Hong Kong (CityUHK) recently discovered a new strategy for developing highly versatile electronics with outstanding performance, using transistors made of mixed-dimensional nanowires and nanoflakes. This innovation paves the way for simplified chip circuit design, offering versatility and low power dissipation in future electronics. In recent decades, as ...

Biomolecular condensates – regulatory hubs for plant iron supply

Biomolecular condensates – regulatory hubs for plant iron supply
2024-02-23
Iron is a micronutrient for plants. Biologists from the Institute of Botany at Heinrich Heine University Düsseldorf (HHU) describe in a study, which has now been published in the Journal of Cell Biology, that regulatory proteins for iron uptake behave particularly dynamically in the cell nucleus when the cells are exposed to blue light – an important signal for plant growth. They found that the initially homogeneously distributed proteins relocated together into “biomolecular condensates” in the cell nucleus shortly after this exposure. Both iron deficiencies and excesses are problematic for plants. They ...

PolyU researchers introduce biomineralization as a sustainable strategy against microbial corrosion in marine concrete

PolyU researchers introduce biomineralization as a sustainable strategy against microbial corrosion in marine concrete
2024-02-23
Microbially induced corrosion (MIC) is a prevalent issue in marine environments, leading to structural damages such as cracking in concrete infrastructure. This corrosion poses a persistent challenge, significantly reducing the lifespan of marine structures and resulting in substantial economic losses. In response to the need for an effective solution to combat the marine corrosion on concrete, researchers of the Hong Kong Polytechnic University have developed a biomineralization approach to protect marine concrete from MIC.   Prof. ...

Genes affect your blood pressure from early childhood

2024-02-23
Certain genes associated with hypertension affect blood pressure from early in life, and they increase the risk of cardiovascular disease as you get older.  However, you can do something about it. “We are talking about really small differences, so small that they may fall within what is considered normal blood pressure. The problem is that they tend to last your whole life,” says PhD Candidate Karsten Øvretveit at the Norwegian University of Science and Technology's (NTNU) Department of ...

Streams connected to groundwater show improved detoxification and microbial diversity

2024-02-23
Washington, D.C. — Feb. 23, 2024 —Streams with ample connections to shallow groundwater flowpaths have greater microbial diversity and are more effective at preventing toxic forms of metals—often products of upstream mining—from entering and being transported downstream. These streams are also better at detoxifying those metals already present. The research is published this week in Applied and Environmental Microbiology, a journal of the American Society for Microbiology. Under favorable conditions, the zone lining a stream channel stores nutrients and oxygen that meet nutritional and respiratory needs of local invertebrates and fish. That ...

Almodóvar receives NIH grant to study pulmonary hypertension in HIV patients

Almodóvar receives NIH grant to study pulmonary hypertension in HIV patients
2024-02-23
Across the globe, more than 39 million people are living with the Human Immunodeficiency Virus (HIV), the virus that causes AIDS, including more than 1.3 million new HIV diagnoses last year. The majority of those afflicted — approximately 76% — have access to antiviral therapy that allows them to live with HIV as a chronic disease. Sharilyn Almodóvar, Ph.D., from the Department of Immunology and Molecular Microbiology at the Texas Tech University Health Sciences Center (TTUHSC) School of Medicine and the TTUHSC Graduate School of Biomedical Sciences, said that even with the widespread ...

SK bioscience’s typhoid conjugate vaccine achieves WHO prequalification

2024-02-23
WHO PQ paves the way for public procurement of SKYTyphoid™ by UN organizations Addition of new vaccine will diversify, expand TCV supply amid expected growing demand   February 23, 2024, SEOUL, Korea – SK bioscience and the International Vaccine Institute (IVI) announced today that the typhoid conjugate vaccine developed by SK bioscience with technology transfer from IVI has achieved the World Health Organization prequalification (PQ), which paves the way for public procurement of the vaccine by UN organizations and gives a boost to the global TCV supply.   WHO PQ certifies the safety, efficacy, and GMP of a vaccine by evaluating its manufacturing ...

The American College of Medical Genetics and Genomics (ACMG) releases points to consider statement on the safety and efficacy of polygenic risk score assessment for embryo selection

2024-02-23
Should we be using polygenic risk score assessment for embryo selection? Providing in-depth analysis, the Social, Ethical and Legal Issues Committee of the American College of Medical Genetics and Genomics (ACMG) has released a new Points to Consider statement to assist healthcare professionals and patients in understanding the safety and utility of preimplantation genetic testing for polygenic disorders (PGT-P) as a clinical service. “Clinical Utility of Polygenic Risk Scores for Embryo Selection: A Points to Consider Statement of the American College of Medical Genetics and Genomics (ACMG)” was published in the College’s flagship journal, Genetics ...

PolyU researchers introduce biomineralisation as a sustainable strategy against microbial corrosion in marine concrete

PolyU researchers introduce biomineralisation as a sustainable strategy against microbial corrosion in marine concrete
2024-02-23
Microbially induced corrosion (MIC) is a prevalent issue in marine environments, leading to structural damages such as cracking in concrete infrastructure. This corrosion poses a persistent challenge, significantly reducing the lifespan of marine structures and resulting in substantial economic losses. In response to the need for an effective solution to combat the marine corrosion on concrete, researchers of the Hong Kong Polytechnic University have developed a biomineralization approach to protect marine concrete from MIC.   Prof. ...

UBC Okanagan researchers look to the past to improve construction sustainability

UBC Okanagan researchers look to the past to improve construction sustainability
2024-02-23
Researchers at UBC Okanagan are revisiting old building practices—the use of by-products and cast-offs—as a way to improve building materials and sustainability of the trade. A technique known as rammed earth construction uses materials that are alternatives to cement and are often more readily available in the environment. One such alternative is wood fly ash, a by-product of pulp mills and coal-fired power plants, explains Dr. Sumi Siddiqua, with UBC Okanagan’s School of Engineering. Industry has been trying to find a use for materials like fly ash ...

New study identifies potential gene targets for management of cassava whitefly, key vector of viral diseases threatening African food security

New study identifies potential gene targets for management of cassava whitefly, key vector of viral diseases threatening African food security
2024-02-23
Whiteflies, particularly the African cassava whitefly (Bemisia tabaci, SSA1-SG1), pose a significant threat to agricultural productivity in Sub-Saharan Africa by transmitting viruses that cause cassava brown streak disease and cassava mosaic virus disease. In a new study published in PeerJ Life & Environment, Dr. Tadeo Kaweesi and his team at the National Agricultural Research Organization identify potential gene targets that could revolutionize the management of this devastating pest and prove vital for food security in the region.   In the article ("In silico prediction of candidate gene targets ...

Twin, the new robotic exoskeleton for lower limbs

Twin, the new robotic exoskeleton for lower limbs
2024-02-23
Milan (Italy), 23 February 2024 – TWIN is the name of the new robotic exoskeleton for lower limbs, designed and developed by Rehab Technologies IIT – INAIL, the joint laboratory between the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) and the Prosthetic Center of INAIL (the prosthetic unit of the National Institute for Insurance against Accidents at Work), which will allow patients to wear it more easily. Presented today in Milan during a press conference held at the Museum of Science and Technology, TWIN was demonstrated ...

Mass shooting lockdown drills help schoolchildren feel safer, US study suggests

2024-02-23
Lockdown drills, practiced to help prepare children for shooting incidents at school, make those who have been exposed to violence feel safer – a new study of thousands of students in the US indicates.    The finding, reported in a new peer-reviewed paper published in the Journal of School Violence, contradicts claims that the drills traumatize children, without making them feel safer.    Ensuring that students feel safe – and are safe – in schools is essential for them to learn and thrive, explains ...

Wake-up call for us all to establish regular healthy sleeping patterns

Wake-up call for us all to establish regular healthy sleeping patterns
2024-02-23
t’s official. Getting the recommended 7-9 hours of sleep a night is currently out of reach for almost one-third of the population as Flinders University experts found 31% of adults had average sleep durations outside the recommended range. The global study of thousands of adults published in Sleep Health found only 15% of people slept the recommended 7-9 hours for five or more nights per week – and among those who did achieve an average of 7-9 hours per night over the nine month monitoring period, about 40% ...

Using mussels and silkworm cocoons to stop organ bleeding

Using mussels and silkworm cocoons to stop organ bleeding
2024-02-23
In recent news, there has been a case where a patient experienced pain due to a surgical procedure involving sutures, resulting in the unintended presence of gauze within the patient's body. Gauze is typically employed to control bleeding during medical interventions, aiding in hemostasis. However, when inadvertently left in the body, it can lead to inflammation and infection. Addressing this issue, recent research has been published by researchers focusing on a hemostatic agent derived from mussels and silkworm cocoons. This hemostatic agent has garnered attention in the academic community due to its efficacy in clotting blood and its safety within ...

New research reveals how cancer hijacks immune cells to promote tumour growth

2024-02-23
A new research study led by A*STAR.Singapore Immunology Network (A*STAR.SIgN) has found that neutrophils—one of the most abundant white blood cells in our body—change drastically in certain cancers, adopting a new function whereby they promote tumour growth. By carefully studying neutrophils as soon as they enter the tumour, scientists from A*STAR.SIgN also uncovered ways to accurately differentiate tumour-promoting neutrophils from normal neutrophils present in the rest of the body. Neutrophils play important and irreplaceable roles in fighting infections, ...
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