UC Irvine advances stem cell research with $4 million CIRM grant for shared resources lab
2024-02-26
Irvine, Calif., Feb. 26, 2024 — The University of California, Irvine has received a five-year, $4 million grant from the California Institute for Regenerative Medicine to establish a shared resources lab in the Sue & Bill Gross Stem Cell Research Center. The facility will offer essential technologies and training for the development of novel in vitro stem cell-based modeling that will serve researchers across the campus and the state.
“Stem cells possess the potential to transform into particular cell types, offering promising avenues for rejuvenating and restoring tissues harmed by injury or affected ...
New discovery suggests significant glacial retreat in West Antarctica began in 1940s
2024-02-26
Among the vast expanse of Antarctica lies the Thwaites Glacier, the world’s widest glacier measuring about 80 miles on the western edge of the continent. Despite its size, the massive landform is losing about 50 billion tons of ice more than it is receiving in snowfall, which places it in a precarious position in respect to its stability.
Accelerating ice loss has been observed since the 1970s, but it is unclear when this significant melting initiated – until now. A new study published in the journal PNAS, led by researchers ...
Butterflies mimic each other’s flight behaviour to avoid predators
2024-02-26
Researchers have shown that inedible species of butterfly that mimic each others’ colour patterns have also evolved similar flight behaviours to warn predators and avoid being eaten.
It is well known that many inedible species of butterfly have evolved near identical colour patterns, which act as warning signals to predators so the butterflies avoid being eaten.
Researchers have now shown that these butterflies have not only evolved similar colour patterns, but that they have also evolved similar ...
What math tells us about social dilemmas
2024-02-26
Human coexistence depends on cooperation. Individuals have different motivations and reasons to collaborate, resulting in social dilemmas, such as the well-known prisoner's dilemma. Scientists from the Chatterjee group at the Institute of Science and Technology Austria (ISTA) now present a new mathematical principle that helps to understand the cooperation of individuals with different characteristics. The results, published in PNAS, can be applied to economics or behavioral studies.
A group of neighbors shares a driveway. Following a heavy snowstorm, the entire driveway is covered in snow, requiring clearance for daily activities. ...
Protecting fish doesn’t have to mean neglecting people, study concludes
2024-02-26
BEAUFORT, N.C. –With fish stocks declining globally, more than 190 countries recently made a commitment to protect about a third of the world’s oceans within “Marine Protected Areas,” or MPAs by the year 2030. But these designated areas of the ocean where fishing is either regulated or outright banned can come at a huge cost to some coastal communities, according to a new analysis.
To help prepare for the expansion of MPAs, an international team of researchers from Duke University, Florida State ...
What will it take for China to reach carbon neutrality by 2060?
2024-02-26
To become carbon neutral by 2060, as mandated by President Xi Jinping, China will have to build eight to 10 times more wind and solar power installations than existed in 2022. Reaching carbon neutrality will also require major construction of transmission lines.
China land use policies will also have to be more coordinated and focused on a nation-wide scale rather than be left to ad hoc decisions by local governments. That’s because 80% of solar power and 55% of wind power will have to be built within 100 miles of major population centers.
These are the conclusions of a new study from ...
A new theoretical development clarifies water's electronic structure
2024-02-26
There is no doubt that water is significant. Without it, life would never have begun, let alone continue today – not to mention its role in the environment itself, with oceans covering over 70% of Earth.
But despite its ubiquity, liquid water features some electronic intricacies that have long puzzled scientists in chemistry, physics, and technology. For example, the electron affinity, i.e. the energy stabilization undergone by a free electron when captured by water, has remained poorly characterized from an experimental ...
Live music emotionally moves us more than streamed music
2024-02-26
How does listening to live music affect the emotional center of our brain? A study carried out at the University of Zurich has found that live performances trigger a stronger emotional response than listening to music from a device. Concerts connect performers with their audience, which may also have to with evolutionary factors.
Music can have a strong effect on our emotions. Studies have shown that listening to recorded music stimulates emotional and imaginative processes in our brain. But what happens when we listen to music in a live setting, for example at a music festival, at the opera or a folk concert? ...
Detroit research team to develop novel strategies to identify genetic contributions to cancer risk and overcome barriers to genetic testing for African Americans
2024-02-26
DETROIT – A team of researchers from Wayne State University and the Barbara Ann Karmanos Cancer Institute has received a five-year, $9.6 million grant from the National Cancer Institute of the National Institutes of Health for the study “Genetic Variation in Cancer Risk and Outcomes in African Americans.” This is a Program Project Grant that includes three large studies. The team will work to improve the identification and clinical management of hereditary and multiple primary cancers in African Americans, a population that is currently underrepresented in genetic research.
According to Ann Schwartz, Ph.D., principal investigator of the project, professor and ...
Vaping can increase susceptibility to infection by SARS-CoV-2
2024-02-26
RIVERSIDE, Calif. -- Vapers are susceptible to infection by SARS-CoV-2, the virus that spreads COVID-19 and continues to infect people around the world, a University of California, Riverside, study has found.
The liquid used in electronic cigarettes, called e-liquid, typically contains nicotine, propylene glycol, vegetable glycerin, and flavor chemicals. The researchers found propylene glycol/vegetable glycerin alone or along with nicotine enhanced COVID-19 infection through different mechanisms.
Study results appear in the American Journal of Physiology.
The researchers ...
Dissecting the roles for excitatory and inhibitory neurons in STXBP1 encephalopathy
2024-02-26
A recent study from Baylor College of Medicine and Texas Children’s Hospital has discovered inhibitory and excitatory neurons play distinct roles in the pathogenesis of STXBP1 encephalopathy, one of the top five causes of pediatric epilepsies and among the most frequent causes of neurodevelopmental disorders. This early-onset disorder is caused by spontaneous mutations in the syntaxin-binding protein 1 (STXBP1) gene. While STXBP1 gene variants impair both excitatory and inhibitory neurotransmission, this study led by Dr. Mingshan Xue, associate professor at Baylor and principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan ...
Boston College biologist awarded $2.5-million NIH grant to explore the role of viral insulins and potential applications to cancers
2024-02-26
Chestnut Hill, Mass (2/26/2024) – Boston College Assistant Professor of Biology Emrah Altindis has been awarded a five-year, $2.5-million grant from the National Institutes of Health to study viral insulins and mechanisms related to IGF-1 receptor protein inhibition and its potential applications in cancer treatment.
Altindis said he and the researchers in his lab will use the grant to learn more about how to use specific viral insulins – particularly insulin-like growth factor-1 (IGF-1) – to inhibit IGF-1 receptor action, which is increased in a range ...
New clinical practice guideline provides evidence-based recommendations for immunotherapy for inhalant allergy
2024-02-26
ALEXANDRIA, VA —The American Academy of Otolaryngology–Head and Neck Surgery Foundation published the Clinical Practice Guideline: Immunotherapy for Inhalant Allergy today in Otolaryngology–Head and Neck Surgery. This clinical practice guideline identifies quality improvement opportunities and provides clinicians trustworthy, evidence-based recommendations on the management of inhalant allergies with immunotherapy, supporting them to provide enhanced care to patients aged 5 years and older who are experiencing symptoms from inhalant allergies.
“More ...
SFU-led research team designs a cutting-edge protein lawnmower
2024-02-26
An SFU-led collaboration has designed the first synthetic protein-based motor which harnesses biological reactions to fuel and propel itself.
“Imagine if a Roomba could be powered only by the dirt it picks up,” says SFU Physics professor Nancy Forde, one of the authors of the study.
The team’s paper, led by SFU Physics PhD graduate Chapin Korosec and published today in Nature Communications, describes a protein-based molecular motor called “The Lawnmower,” which has been designed to cut a lawn of peptide “grass.” ...
Metal in glitter impairs aquatic plant growth, study shows
2024-02-26
Glitter is used in a wide array of colors and shapes in apparel, footwear, cosmetics, makeup, handbags, festive decorations, arts and crafts, and jewelry, among many other applications. During the Carnival holidays, hundreds of thousands of Brazilians cover parts of their bodies with it while dancing in the streets. Its brilliance is dazzling but it is considered an emerging pollutant by many scientists: like other microplastics (small plastic pieces less than 5 mm long), it is not filtered by wastewater treatment plants and ends up in rivers and the sea, interfering with aquatic life in various ways.
A study conducted at the Federal University of ...
Scientists assemble a richer picture of the plight and resilience of the foothill yellow-legged frog
2024-02-26
(Santa Barbara, Calif.) — Up to only a few inches in length, with a lemon-hued belly, the foothill yellow-legged frog may seem unassuming. But its range once stretched from central Oregon to Baja California. In 2023, it was listed under the federal Endangered Species Act. Its rapidly decreasing range is due in part to a fungal pathogen called Batrachochytrium dendrobatidis, or Bd, that has devastated amphibians around the world.
A team of researchers, including UC Santa Barbara’s Andrea Adams, has conducted the most comprehensive study to date ...
Neuropsychiatric symptoms predict which patients with mild cognitive impairment develop Alzheimer’s disease.
2024-02-26
As the years add up, it's common to notice slight changes in our ability to remember and think. Older people who have more marked changes than their peers can be diagnosed with mild cognitive impairment (MCI). Currently, we can’t easily predict which of these patients will develop Alzheimer’s disease and which will not.
“It's hard to predict which patients will have a more rapid progression and receive a diagnosis of dementia,” said Maria Vittoria Spampinato, M.D., division director of Neuroradiology at the Medical University of South Carolina.
“It’s important ...
Resurrecting niobium for quantum science
2024-02-26
For years, niobium was considered an underperformer when it came to superconducting qubits. Now scientists supported by Q-NEXT have found a way to engineer a high-performing niobium-based qubit and so take advantage of niobium’s superior qualities.
When it comes to quantum technology, niobium is making a comeback.
For the past 15 years, niobium has been sitting on the bench after experiencing a few mediocre at-bats as a core qubit material.
Qubits are the fundamental components of quantum devices. One qubit type relies on superconductivity to process information.
Touted for its superior qualities as a superconductor, niobium was always a promising ...
Long-term data reveals SARS-CoV-2 infection and vaccine-induced antibody responses are long-lasting
2024-02-26
A long-term analysis conducted by leading microbiologists at the Icahn School of Medicine at Mount Sinai reveals that antibody responses induced by COVID-19 vaccines are long-lasting. The study results, published online in the journal Immunity on February 22, challenge the idea that mRNA-based vaccine immunity wanes quickly.
The emergence of SARS-CoV-2, the virus that causes COVID-19, in late 2019 sparked the global pandemic that is now in its fifth year. Vaccines that were developed at record speed have saved millions of lives. However, the emergence of SARS-CoV-2 variants and waning immunity have decreased ...
Shaping the future of phage therapy: The 7th World Conference on Targeting Phage Therapy in Malta aims to transform clinical trials through translational research
2024-02-26
The 7th World Conference on Targeting Phage Therapy 2024, two-day event dedicated to advancing the field of phage research and therapy will be hosted at Corinthia Palace Malta on June 20-21.
Robert T. Schooley, M.D., Professor of Medicine at the University of California, San Diego, Co-Director of the Center for Innovative Phage Applications and Therapeutics, and member of the Executive Committee for the University of California Disaster Resilience Network, will introduce the messages and strategies behind phages therapy 2024.
His talk titled “Phage Therapeutics 2024: Essential Translational Research Components for ...
GZ17-6.02 with bexarotene kills mycosis fungoides cells
2024-02-26
“The present studies were performed to extend our knowledge of GZ17-6.02 biology from that known in solid tumor cell types such as prostate cancer cells to liquid tumor cell types, for example, mycosis fungoides.”
BUFFALO, NY- February 26, 2024 – A new research paper was published in Oncotarget's Volume 15 on February 8, 2024, entitled, “GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells.”
In this new study, researchers Michael R. Booth, Laurence Booth, Jane L. Roberts, Cameron West, and Paul Dent from Virginia Commonwealth University and Genzada Pharmaceuticals investigated the therapeutic agent GZ17-6.02, composed of curcumin, ...
University of Tennessee Health Science Center professor awarded $1.5m to study 'root causes' of disparity in breast cancer survival of Black women and white women
2024-02-26
Memphis, Tenn. (February 26, 2024) – Shelley White-Means, PhD, a professor of Health Economics in the Department of Interprofessional Education and the director of the Consortium for Health Education, Economic Empowerment and Research (CHEER) at UT Health Science Center, recently received a $1.5 million, four-year grant from the National Institute on Minority Health and Health Disparities to explore the root causes of the disparity in breast cancer survival of Black women compared to white women.
Dr. White-Means and a team will look beyond the social determinants of health to explore what she terms “the intersectionality of race, ...
Steering and accelerating electrons at the microchip scale
2024-02-26
Stanford researchers are getting closer to building a tiny electron accelerator based on “accelerator-on-a-chip” technology with broad potential applications in studying physics as well as medical and industrial uses.
The researchers have demonstrated that a silicon dielectric laser accelerator, or DLA, can now both speed up and confine electrons, creating a focused beam of high-energy electrons. “If the electrons were microscopic cars, it’s as if, for the first time, we’re steering and we have our foot on the gas,” said Payton Broaddus, PhD ’23 in electrical engineering and the lead author on a paper published on ...
City of Hope scientists devise novel strategy to seek and destroy leukemia stem cells
2024-02-26
FINDINGS
Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have devised an innovative approach to target and destroy hard-to-kill leukemia stem cells. The journal Blood published the preclinical findings today.
By overcoming challenges, such as drug resistance and treatment relapse common to patients with acute myeloid leukemia (AML), the therapy method could provide a less toxic and more effective approach for older and sicker patients who don’t quality for stem cell transplants — currently the only cure for AML available.
Type II interferon (IFNy), a substance produced by immune cells, disrupts ...
Laser-focused look at spinning electrons shatters world record for precision
2024-02-26
NEWPORT NEWS, VA – Scientists are getting a more detailed look than ever before at the electrons they use in precision experiments.
Nuclear physicists with the U.S. Department of Energy’s Thomas Jefferson National Accelerator Facility have shattered a nearly 30-year-old record for the measurement of parallel spin within an electron beam – or electron beam polarimetry, for short. The achievement sets the stage for high-profile experiments at Jefferson Lab that could open the door to new physics discoveries.
In a peer-reviewed ...
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