ANN ARBOR, Mich.---Strategies for preventing the spread of whooping cough---on the rise in the United States and several other countries in recent years---should take into account how often people in different age groups interact, research at the University of Michigan suggests. The findings appear in the Nov. 12 issue of the journal Science. Thanks to widespread childhood vaccination, whooping cough (pertussis) once seemed to be under control. But the illness, which in infants causes violent, gasping coughing spells, has made a comeback in some developed countries ...

Boston, Mass. - While it has become clear in recent years that susceptibility to pain has a strong inherited component, very little is known about actual "pain genes" and how they work. In the November 12th issue of Cell, researchers at Children's Hospital Boston and their collaborators report on a novel human pain gene. People with minor variations in this gene showed clear differences in susceptibility to acute heat pain and chronic back pain. Corroborating mouse studies give some clues as to how the gene controls pain sensitivity. The gene was uncovered in a genome-wide ...

Controlling and modulating the flow of light is essential in today's telecommunications-based society. Professor Tobias Kippenberg and his team in EPFL's Laboratory of Photonics and Quantum Measurements have discovered a novel way to couple light and vibrations. Using this discovery, they built a device in which a beam of light traveling through an optical microresonator could be controlled by a second, stronger light beam. The device thus acts like an optical transistor, in which one light beam influences the intensity of another. Their optical microresonator has two ...

Individuals who suffer from severe acne are at an increased risk of attempting suicide, according to a paper published on bmj.com today. The study also finds that an additional risk may be present during and up to one year after treatment with isotretinoin, a commonly prescribed drug for severe acne. However, the authors stress that this additional risk is most likely due to the acne itself, rather than the drug treatment. Isotretinoin (commonly marketed as Roaccutane, Accutane, Amnesteem, Claravis, Clarus or Decutan) has been used to treat severe acne since the 1980s. ...

New research has revealed up to 16,000 endangered turtles are being caught each year by villagers in just one region of Madagascar, despite a government ban. Researchers from the University of Exeter and Blue Ventures Conservation say the figure, thought to be a conservative estimate, is the first direct assessment of turtle exploitation on the island. The study highlights the extent of small-scale fishing, traditionally very difficult to monitor, and could be vital in finding a way to sustainably manage turtle fishing in the region. Dr Annette Broderick, from the ...

"The biggest surprise to me was that we could rescue the autistic phenotype [in the human cells] to something close to normal," said Alysson Muotri of the University of California San Diego. The researchers made the discovery by first transforming adult cells taken from patients with Rett Syndrome into induced pluripotent stem cells (iPS cells) using an established cocktail. iPS cells look and act very much like embryonic stem cells. Those stem cells were able to form functional neurons in cell culture. However, neurons derived from Rett Syndrome patients exhibited ...

They show that one of those genes in particular has a long evolutionary history, as evidenced by the fact that it plays a role in pain sensing in flies, mice and humans. At least in mice, the newly described gene is also linked to a condition known in humans as synesthesia, in which one sensory experience triggers the perception of another sense. "We found lots of new genes and pathways that have never been implicated in pain before," said Josef Penninger of the Institute of Molecular Biotechnology of the Austrian Academy of Sciences. "From a helicopter view, this ...

Night-time violence among young Spaniards is becoming ever more common, according to a research study carried out by the European Institute of Studies on Prevention. The study shows that 5.2% of young people carry weapons when they go out at night, 11.6% have been attacked or threatened, and 23% have got into a fight at some time. "Reports about young people being attacked or injured in fights when they go out at night are becoming increasingly common", Amador Calafat, lead author of the study and a researcher at the European Institute of Studies on Prevention (IREFREA), ...

An international team led by the Forest Technology Centre of Catalonia has carried out the first large-scale study of the threats facing freshwater fish in the Mediterranean basin. Invasive species, along with over-exploitation of water resources, are the most important pressures, and those that expose fish to the greatest risk of extinction. "The continental fish of the Mediterranean basin are one of the most threatened biological groups in the world", Miguel Clavero, lead author of the study and a researcher from the Landscape Ecology Group of the Forest Technology ...

After four years of conducting intensive calculations in the supercomputer MareNostrum at the Barcelona Supercomputing Center, scientists headed by Modesto Orozco at the Institute for Research in Biomedicine (IRB Barcelona) have presented the world's largest data base on protein motions. Called MoDEL, this new database holds more than 1,700 proteins and is partially accessible through Internet to researchers worldwide. MoDEL has been developed to study the basic biology of proteins and to accelerate and facilitate the design of new pharmaceutical agents. "Nowadays we ...

Now that the 2010 election is over, here is something to consider for the 2012 race: If you want to fatten your company's profits, contribute to a political campaign. A study by two College of Business Administration professors at the University of Tennessee, Knoxville, found that when firms engage in corporate political activities, such as lobbying and making campaign contributions, they enjoy about 20 percent higher performance. The study, by Russell Crook and David Woehr, along with Sean Lux of the University of South Florida, entitled "Mixing Business with Politics: ...

Both the bully and the victim's individual characteristics, rather than the wider social environment, explain why bullying occurs, according to Swedish teenagers. The new study, by Dr. Robert Thornberg and Sven Knutsen from Linköping University in Sweden, also shows that 42 percent of teenagers blamed the victim for the bullying. The study is published online in Springer's journal, Child & Youth Care Forum. In one of the rare studies investigating young people's views on why bullying takes place in school, Thornberg and Knutsen explored how teenagers explain bullying ...

Electronic components are getting smaller and smaller, with microelectronic components gradually being replaced by nanoelectronic ones. On nanoscale dimensions, silicon, which is at the present stage the most commonly used material in semiconductor technology, reaches however a limit, preventing further miniaturization and technological progress. New electronic materials are therefore in great demand. Due to its outstanding electronic properties, graphene, a two-dimensional carbon network, is considered as a possible replacement. However, several obstacles must be overcome ...

Fear arises in the almond-shaped brain structure known as the amygdala. It is the amygdala which processes the strange noise, shadowy figure or scary face and not only triggers palpitations or nausea but can also cause us to flee or freeze. That much has long been known about the function of this part of the brain. What remains largely unclear, however, is precisely how fear develops, and which of the countless neurons in the amygdaloid region are involved in this process. But finding answers to these questions is vital for those who wish to improve the quality of life ...

Spanish and American researchers have conducted a mineralogical and chemical analysis to ascertain the origin of "terra rossa" soil in the Mediterranean. The results of the study reveal that mineral dust from the African regions of the Sahara and Sahel, which emit between 600 and 700 tonnes of dust a year, brought about the reddish soil in Mediterranean regions such as Mallorca and Sardinia between 12,000 and 25,000 years ago. "The first hint of the relationship between African dust and certain soils in the region of the Mediterranean is their reddish or reddish-brown ...

MAYWOOD, Ill. -- Alcohol does much more harm to the body than just damaging the liver. Drinking also can weaken the immune system, slow healing, impair bone formation, increase the risk of HIV transmission and hinder recovery from burns, trauma, bleeding and surgery. Researchers released the latest findings on such negative effects of alcohol during a meeting Nov. 19 of the Alcohol and Immunology Research Interest Group, held at Loyola University Medical Center. At Loyola, about 50 faculty members, technicians, post-doctoral fellows and students are conducting alcohol ...

DURHAM, N.C. -- Leaks from carbon dioxide injected deep underground to help fight climate change could bubble up into drinking water aquifers near the surface, driving up levels of contaminants in the water tenfold or more in some places, according to a study by Duke University scientists. Based on a year-long analysis of core samples from four drinking water aquifers, "We found the potential for contamination is real, but there are ways to avoid or reduce the risk," says Robert B. Jackson, Nicholas Professor of Global Environmental Change and professor of biology at ...

HOUSTON -- (Nov. 11, 2010) -- Future computers may run a little sweeter, thanks to a refinement in the manufacture of graphene at Rice University. Rice researchers have learned to make pristine sheets of graphene, the one-atom-thick form of carbon, from plain table sugar and other carbon-based substances. They do so in a one-step process at temperatures low enough to make graphene easy to manufacture. The lab of Rice chemist James Tour reported in the online version of the journal Nature this week that large-area, high-quality graphene can be grown from a number of ...

JUPITER, FL, November 9, 2010 – For Immediate Release – Scientists from the Florida campus of The Scripps Research Institute have identified for the first time a novel mechanism that regulates circadian rhythm, the master clock that controls the body's natural 24-hour physiological cycle. These new findings could provide a new target not only for jet lag, shift work, and sleep disturbances, but also for disorders that result from circadian rhythm disruption, including diabetes and obesity as well as some types of cancer. The study is published in the November 12, 2010 ...

WINSTON-SALEM, N.C. – Thursday, Nov. 11, 2010 – Arsenic, a toxic compound with a reputation as a good tool for committing homicide, has a significant positive effect on the survival of patients with acute promyelocytic leukemia (APL), when administered after standard initial treatment, according to a new, multi-center study led by a researcher at Wake Forest University Baptist Medical Center. While arsenic trioxide (As2O3) is known by clinicians to be a highly effective treatment for patients with relapsed APL, its benefit earlier in treatment, after first remission, ...

INDIANAPOLIS – Researchers report that a drug commonly used to treat diabetes may also retard the growth of fluid-filled cysts of the most common genetic disorder, polycystic kidney disease. PKD does not discriminate by gender or race and affects one in 1,000 adults worldwide. Researchers from the schools of Science and Medicine at Indiana University-Purdue University Indianapolis and colleagues from the Mayo Clinic report this month in the online peer-reviewed journal PPAR Research that pioglitazone appears to control the growth of PKD cysts. Using a rat model that ...

Montreal, November 11, 2010 – People affected by anxiety and depression should receive an additional cardiac test when undergoing diagnosis for potential heart problems, according to a new study from Concordia University, the Université du Québec à Montréal and the Montreal Heart Institute. As part of this study, published in the Journal of Cardiopulmonary Rehabilitation and Prevention, a large sample of patients received a traditional electrocardiogram (ECG), where they were connected to electrodes as they exercised on a treadmill. Patients also received a more complex ...

New research from the University of Warwick, to be presented at the World's largest supercomputing conference next week, pits China's new No. 1 supercomputer against alternative US designs. The work provides crucial new analysis that will benefit the battle plans of both sides, in an escalating war between two competing technologies. Professor Stephen Jarvis, Royal Society Industry Fellow at the University of Warwick's Department of Computer Science, will tell some of the 15,000 delegates in New Orleans next week, how general-purpose GPU (GPGPU) designs used in China's ...

BATON ROUGE – LSU's Sibel Bargu, along with her former graduate student Ana Garcia, from the Department of Oceanography and Coastal Sciences in LSU's School of the Coast & Environment, has discovered toxic algae in vast, remote regions of the open ocean for the first time. The recent findings were published in the Nov. 8 edition of one of the most prestigious scientific journals, the Proceedings of the National Academy of Sciences, or PNAS. Harmful algal blooms, or HABs, are reported as increasing both geographically and in frequency along populated coastlines. Bargu's ...

ANN ARBOR, Mich. — Provisions of new federal health care reforms will move the country toward a primary care medical home for patients, but the nation may not have enough primary care doctors to handle the workload, according to a study by the University of Michigan Health System. Still, the concept of shifting patients to a medical home could save time and money and allow specialists to focus on complex patient care, according to the study published online ahead of print in the journal Medical Care. "I don't think anyone would question that there are too few primary ...