A malaria drug treatment could save babies’ lives
2023-12-19
Wars, drought, displacement, and instability are causing a dramatic increase in the number of pregnant and breastfeeding women around the world who suffer from malnutrition. Without access to sufficient nutrients in the womb, babies born to these women are more likely to die due to complications like pre-term birth, low birth weight, and susceptibility to diseases like malaria. To try to reduce the risk of malarial infection, the WHO recommends that pregnant women in low-income countries be treated with a combination of the antimalarial drugs sulfadoxine and pyrimethamine ...
Engineered human heart tissue shows Stanford Medicine researchers the mechanics of tachycardia
2023-12-19
Heart rates are easier to monitor today than ever before. Thanks to smartwatches that can sense a pulse, all it takes is a quick flip of the wrist to check your heart. But monitoring the cells responsible for heart rate is much more challenging — and it’s encouraged researchers to invent new ways to analyze them.
Joseph Wu, M.D., Ph.D., director of the Stanford Cardiovascular Institute and professor of medicine and of radiology, has devised a new stem cell-derived model of heart tissue ...
Molecular jackhammers’ ‘good vibrations’ eradicate cancer cells
2023-12-19
The Beach Boys’ iconic hit single “Good Vibrations” takes on a whole new layer of meaning thanks to a recent discovery by Rice University scientists and collaborators, who have uncovered a way to destroy cancer cells by using the ability of some molecules to vibrate strongly when stimulated by light.
The researchers found that the atoms of a small dye molecule used for medical imaging can vibrate in unison ⎯ forming what is known as a plasmon ⎯ when stimulated by near-infrared light, causing the cell membrane of cancerous cells to rupture. ...
Nearly 30% of caregivers for severe stroke survivors experience psychological distress
2023-12-19
Stroke is an abrupt, devastating disease that instantly changes a person’s life and has the potentially to cause lasting disability or death. However, the condition also has profound effects on the patient’s loved ones — who are often called to make difficult decisions quickly.
A new study led by Michigan Medicine finds that nearly 30% of caregivers of severe stroke patients experience high levels of anxiety, depression or post-traumatic stress during the first year after the patient leaves the hospital.
The results are published in Neurology.
“As physicians, we usually concentrate on our ...
MSU research suggests pandas are active posters on ‘social media’
2023-12-19
MSU has a satellite uplink/LTN TV studio and Comrex line for radio interviews upon request.
Images
Pandas, long portrayed as solitary creatures, do hang with family and friends — and they’re big users of “social media.” Scent-marking trees serve as a panda version of Facebook.
An article in the international journal Ursus paints a new lifestyle picture of the beloved bears in China’s Wolong National Nature Reserve, a life that’s shielded from human eyes because they’re shy, rare and live in densely forested, remote areas. No one really knows how pandas hang, but a new study indicates pandas are around others more than previously thought. ...
UTHSC, Vanderbilt University receive $2.4 million grant to promote diversity in speech-language pathologists for high-need children
2023-12-19
The Department of Audiology and Speech Pathology at the University of Tennessee Health Science Center and the Department of Hearing and Speech Sciences at Vanderbilt University have secured a $2,399,454 grant to fund a five-year project to address the need for diversity in highly trained professionals in speech-language pathology.
The project, known as Project PAL (Preparing Academic Leaders in Speech-Language Pathology to Teach, Conduct Research, and Engage in Professional Service to Improve Outcomes for Children with High Need Communication Disorders), ...
American University receives $5.7 million from NSF to bridge research and policy, address real-world challenges
2023-12-19
American University won a $5.7 million cooperative research agreement from the U.S. National Science Foundation’s Accelerating Research Translation program. The award will help AU foster greater use of evidence in the public and private sectors by producing new knowledge on best practices in research translation, training scholars in the effective conduct of research translation, and supporting the dissemination of research findings that have the potential to benefit society.
The ART program ...
UTRF Innovation Awards celebrate UTHSC researchers
2023-12-19
The University of Tennessee Research Foundation (UTRF) celebrated the researchers whose achievements are making life better locally, nationally, and globally at its annual Innovation Awards ceremony, held December 14 at the Mooney Library at the University of Tennessee Health Science Center (UTHSC) in Memphis.
The Innovation Awards recognize researchers from all over the UT System who partner with UTRF to bring their innovations to market. “Turning research into practical, sustainable solutions calls for resilience, adaptability, and market savvy. Let's collectively celebrate the foundational research successes that made ...
Groundbreaking hip-focused physical therapy reduces low back pain
2023-12-19
When the University of Delaware’s Gregory Hicks started his research career two decades ago, he was one of only a few people in the United States studying chronic low back pain in people over 60 years old.
Fast-forward to today, the research on back pain has ramped up, yet studies of older adults with the problem are still sparse.
“Unfortunately, the societal attitude is that older people don’t warrant the same level of care that younger people do when it comes to musculoskeletal problems,” said Hicks, Distinguished Professor of Health Sciences at UD. “But I don’t believe that for a ...
Researchers report detailed analysis of heart injury caused by yellow fever virus
2023-12-19
To fill gaps in knowledge of yellow fever (YF), a group of researchers in Brazil affiliated with the Department of Pathology at the University of São Paulo’s Medical School (FM-USP), Hospital das Clínicas (HC, the hospital complex run by FM-USP), the Heart Institute (InCor, linked to HC) and Emílio Ribas Institute of Infectious Diseases (IIER) decided to study the pathogenesis of YF-associated heart injury.
The team was led by Fernando Rabioglio Giugni, a cardiologist, and Amaro Nunes Duarte-Neto, an infectious disease specialist and pathologist; both work at FM-USP.
“There’s still no specific treatment for yellow fever. Patients receive ...
David Kaplan named fellow of the National Academy of Inventors
2023-12-19
David Kaplan, the Stern Family Endowed Professor of Engineering, has been named a fellow of the National Academy of Inventors (NAI). Election as an academy fellow is the highest professional distinction awarded solely to inventors. The NAI was founded to recognize and encourage inventors with U.S. patents and enhance the visibility of academic technology and innovation.
As a member of the Class of 2023, Kaplan will be honored at the NAI’s annual meeting on June 18, 2024 in Raleigh, North ...
Research spotlight: Structural analysis and inhibition of human LINE-1 ORF2 protein reveals novel adaptations and functions
2023-12-19
Martin Taylor, MD, PhD, a physician investigator in the Department of Pathology at Massachusetts General Hospital and an instructor in Pathology at Harvard Medical School, is the lead corresponding author of a new study in Nature, Structural Analysis and Inhibition of Human LINE-1 ORF2 Protein Reveals Novel Adaptations and Functions.
What Question Were You Investigating?
About a fifth of the human genome is half a million copies of a transposon, a virus-like element known as LINE-1 (L1). L1 was ignored as “junk DNA” for years but is increasingly recognized to contribute to the pathology of autoimmunity, ...
Assisted reproductive technologies not associated with body mass index in children, except when using frozen embryos – according to new Danish study
2023-12-19
Assisted reproductive technologies not associated with body mass index in children, except when using frozen embryos – according to new Danish study
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In your coverage, please use this URL to provide access to the freely available paper in PLOS Medicine: http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1004324
Article Title: Overweight or obesity in children born after assisted reproductive technologies in Denmark: A population-based cohort study
Author Countries: ...
Novel approach emerging for rescuing limbs at risk
2023-12-19
Across the United States, about 2 million people are living with an amputation and another 185,000 amputations occur every year, according to the Amputee Coalition, a Washington DC-based support group. About 54% of these lost limbs were caused by vascular disease, including diabetes and peripheral arterial disease (PAD).
And as more people are diagnosed with diabetes, in the US and worldwide, the number of amputations keeps rising.
Now, experts at Cincinnati Children’s in collaboration with colleagues from Kanazawa University in Japan, have uncovered a new way to prompt blood vessel ...
Socialization for success: Two recent studies expand our understanding of how early social housing helps dairy calves thrive
2023-12-19
Philadelphia, December 19, 2023 – Dairy industry professionals continuously work to ensure the highest possible welfare for dairy calves, including fine-tuning their housing to improve overall health, well-being, and performance. Two new studies in JDS Communications are illuminating our understanding of paired housing in the critical newborn and pre-weaned stages of dairy lives by showing that housing designed to facilitate early socialization can build behavior skills, shape calf personalities, and ultimately, set up animals ...
Sirtuin 6 activation rescues the age-related decline in DNA damage repair in chondrocytes
2023-12-19
“[...] the biological mechanisms linking aging and osteoarthritis prevalence remain largely unknown.”
BUFFALO, NY- December 19, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, “Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes.”
While advanced age is widely recognized as the greatest risk factor for osteoarthritis (OA), the biological mechanisms behind this connection remain unclear. Previous work has ...
Innovative optical technique for simultaneously producing and shaping gigahertz burst pulses
2023-12-19
The generation and manipulation of high-repetition pulses hold great promise across various applications, including high-speed photography, laser processing, and acoustic wave generation. Gigahertz (GHz) burst pulses, with intervals ranging from ~0.01 to ~10 nanoseconds, are particularly valued for visualizing ultrafast phenomena and improving laser processing efficiency.
While methods for producing GHz burst pulses exist, challenges persist, such as low throughput of pulse energy, poor tunability of pulse intervals, and the complexity ...
3D material found to break down antidepressant that contaminates water bodies worldwide
2023-12-19
An article published in the Chemical Engineering Journal describes a strategy to produce a material based on zinc oxide (ZnO) capable of degrading sertraline, an antidepressant that has been detected, like other drugs, in groundwater worldwide and is considered an emerging pollutant. This kind of substance has certain physicochemical properties that hinder removal by conventional wastewater treatment methods.
The research was supported by FAPESP and conducted in Brazil by scientists at the Center for Development of Functional Materials (CDMF), the Brazilian ...
High Performance Computing Center of the University of Stuttgart and Hewlett Packard Enterprise to build exascale supercomputer
2023-12-19
The University of Stuttgart and Hewlett Packard Enterprise (HPE) have announced an agreement to build two new supercomputers at the High-Performance Computing Center of the University of Stuttgart (HLRS).
In the first stage, a transitional supercomputer, called Hunter, will begin operation in 2025. This will be followed in 2027 with the installation of Herder, an exascale system that will provide a significant expansion of Germany’s high-performance computing (HPC) capabilities. Hunter and Herder will offer researchers ...
Gentle x-ray imaging of small living specimens
2023-12-19
X-ray imaging visualizes hidden structures and processes in living cells and organisms. The radiation that consists of highly energy-rich electromagnetic waves, however, has an ionizing effect and may damage the genetic material. This limits the possible observation period. While conventional X-ray images of soft tissue are of low contrast, phase contrast methods produce far better image contrasts at a reduced radiation dose. With higher resolution, however, gentle imaging becomes increasingly difficult, as a higher dose is required. Moreover, ...
Pushing compressed sensing to real-time edge applications
2023-12-19
Recently, a research team led by Prof. Sun Zhong at Peking University reported an analog hardware solution for real-time compressed sensing recovery, which has been published as an article titled "In-memory analog solution of compressed sensing recovery in one step" in Science Advances. In this work, a design based on a resistive memory (also known as memristor) array for performing instantaneous matrix-matrix-vector multiplication (MMVM) is first introduced. Based on this module, then an analog matrix computing circuit that solves compressed sensing (CS) recovery in one step (within few microseconds) is disclosed.
CS ...
The science behind snowflakes
2023-12-19
Tim Garrett has devoted his scientific career to characterizing snowflakes, the protean particles of ice that form in clouds and dramatically change as they fall to Earth.
Now the University of Utah atmospheric scientist is unlocking the mystery of how snowflakes move in response to air turbulence that accompanies snowfall using novel instrumentation developed on campus. And after analyzing more than half a million snowflakes, what his team has discovered has left him astonished.
Rather than something incomprehensibly complicated, predicting how snowflakes move proved to be surprisingly ...
COVID-19 infection causes teen’s vocal cord paralysis in first-of-its-kind case
2023-12-19
Physician-researchers from Mass Eye and Ear, a member of Mass General Brigham, report the first pediatric case of bilateral vocal cord paralysis after COVID-19 (SARS-CoV-2) infection. The patient, an otherwise healthy 15-year-old female, came to the emergency department at Massachusetts General Hospital with symptoms of respiratory distress nine days after diagnosis with SARS-CoV-2 infection. Examination with an endoscope revealed bilateral vocal cord paralysis, which is an immobility of both vocal cords found in the larynx or voice box. The researchers concluded that this paralysis was likely a downstream ...
Vervet monkeys follow different social “norms” and respond to “peer pressure,” new long-term study shows
2023-12-19
People living in different communities follow different social customs or norms. In some places, for instance, it might be standard practice to greet each person you see on the street, while in others that simply isn’t done. In some cases, such differences may even vary from one neighborhood to the next. Now researchers reporting in the journal iScience on December 19 have found similarly varied social traditions and styles among neighboring groups of vervet monkeys.
“We report the existence of behavioral traditions of social customs in vervet ...
Would you like to groom me?
2023-12-19
Researchers at UNIL’s Department of Ecology and Evolution reveal the existence of social traditions in vervet monkeys. This work was published in iScience on December 19, 2023.
British tits have learned from each other how to pierce the lids of milk bottles left on doorsteps. On the island of Koshima, Japanese macaques started washing sweet potatoes to rid them of sand. The animal realm is full of examples of traditions linked to food, tool use or hunting techniques that have spread within specific communities. However, few traditions of social nature, i.e. how individuals interact with each other, have been described.
A ...
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