Plant genomics has come a long way since Cold Spring Harbor Laboratory (CSHL) helped sequence the first plant genome. But engineering the perfect crop is still, in many ways, a game of chance. Making the same DNA mutation in two different plants doesn’t always give us the crop traits we want. The question is why not? CSHL plant biologists just dug up a reason. CSHL Professor and HHMI Investigator Zachary Lippman and his team discovered that tomato and Arabidopsis thaliana plants can use very different regulatory systems to control the same exact ...

1. Using data science techniques, a NIMS–Tohoku University research team has discovered that different thermal conductivities exhibited by an amorphous material with the same composition are attributable to the sizes of atomic rings in its atomic structure. This is one of the first studies demonstrating that the structural features of amorphous materials can be correlated with their physical properties. 2. It is already feasible to synthesize amorphous materials with the same compositions but different thermal conductivities. However, the structural factors responsible for differences in thermal conductivity had yet to be identified due to a lack of appropriate analytical ...

Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators. They have conducted the first whole genome sequencing analysis of male breast cancer, which looked at the complete DNA landscape of tumor samples from 10 patients. This is an important step in viewing breast cancer in men, which represents less than 1 percent of all breast cancer cases each year, as a unique disease. Though most research has focused on women with breast cancer, the incidence in men has increased at a much faster rate than in women over the last 40 years. Also, ...

According to the CDC, the suicide rate among young people ages 10‒24 increased 62% from 2007 through 2021. The CDC’s Youth Risk Behavior Summary reports that in 2021, 22% of high school students seriously considered attempting suicide during the year and 18% made a suicide plan. These statistics indicate a mental health crisis facing our youth. How can we identify children in crisis? Who is being missed? The Brain & Behavior Research Foundation (BBRF) is hosting a free webinar, “Detection of Suicide-Related Emergencies Among ...

Madhavi Venkatesan, PhD, Editor-in-Chief of the peer-reviewed journal Sustainability and Climate Change and founder of Sustainable Practices, has been named USA TODAY Woman of the Year for the state of Massachusetts in recognition of her outstanding efforts to eliminate single-use plastic bottles across Cape Cod and the Islands. With economics and sustainability at the forefront, Venkatesan established Sustainable Practices in 2016, aiming to address pressing environmental issues through innovative solutions. Since then, she and her nonprofit team have spearheaded ...

In the predawn hours of Sept. 5, 2021, engineers achieved a major milestone in the labs of MIT’s Plasma Science and Fusion Center (PSFC), when a new type of magnet, made from high-temperature superconducting material, achieved a world-record magnetic field strength of 20 tesla for a large-scale magnet. That’s the intensity needed to build a fusion power plant that is expected to produce a net output of power and potentially usher in an era of virtually limitless power production. The test was immediately declared ...

A vaccine against Zika virus is safe and effective when administered both before and during pregnancy, according to new research published in npj Vaccines. The purified, inactivated Zika vaccine (ZPIV) candidate, developed by Walter Reed Army Institute of Research (WRAIR), is being evaluated in animal models at Texas Biomedical Research Institute (Texas Biomed) in collaboration with WRAIR and Trudeau Institute in New York. The vaccine candidate has previously been shown to effectively block prenatal Zika virus transmission when given to nonhuman primates ...

PROVIDENCE, R.I. [Brown University] — Childhood lead exposure, primarily from paint and water, is a significant health concern in the United States, but a new study has identified a surprising additional source of lead exposure that may disproportionately harm children: firearms. A team led by researchers at Brown University found an association between household firearm ownership and elevated lead levels in children’s blood in 44 states, even when controlling for other major lead exposure ...

The role of African women and young people engaged in agricultural service provision has been investigated in a new CABI-led study published in the CABI Agriculture and Bioscience journal. By combining a literature review with ongoing action research in Kenya, the scientists provide insights into the main characteristics, benefits, and shortfalls of business models for engaging women and young people in agricultural service provision in Africa. ‘Not a panacea to the challenges faced’ The findings show that the engagement of African women and young people in agricultural service provision is ‘not a panacea to the challenges they face’ such as limited ...

The Redox Medicine Society (RMS) is pleased to announce the 26th International Conference of the Redox Medicine, taking place from June 27 to June 28, 2024, in Paris, France. Redox Medicine 2024 will gather the world’s leading experts in redox biology, signaling pathways, and their impact on medicine, promising to highlight the current and future state of Redox Medicine. The influence of redox processes, redox biology, and redox signaling pathways extends across a broad spectrum of physiological and pathological phenomena. A deeper comprehension of the cellular and molecular mechanisms driving these redox interactions is pivotal for the development of innovative ...

If you’ve driven the mostly flat stretch of I-25 in Colorado from Pueblo to Trinidad, you’ve seen them: the Spanish Peaks, twin mountains that soar into the sky out of nowhere, reaching altitudes of 13,628 and 12,701 feet above sea level. In a new study, geologists from the University of Colorado Boulder have laid out a timeline for the emergence of these majestic but isolated mountains. The team’s findings could bring scientists closer to answering one of the most enduring puzzles in Colorado geology: What made ...

Looking deeply into space and time, two teams using NASA’s James Webb Space Telescope have studied the exceptionally luminous galaxy GN-z11, which existed when our 13.8 billion-year-old universe was only about 430 million years old. Initially detected with NASA’s Hubble Space Telescope, this galaxy — one of the youngest and most distant ever observed  — is so bright that it is challenging scientists to understand why. Now, GN-z11 is giving up some of its secrets. Vigorous Black Hole Is Most Distant Ever Found A team studying ...

UNIVERSITY PARK, Pa. — Fat tissue holds the key to 3D printing layered living skin and potentially hair follicles, according to researchers who recently harnessed fat cells and supporting structures from clinically procured human tissue to precisely correct injuries in rats. The advancement could have implications for reconstructive facial surgery and even hair growth treatments for humans.  The team’s findings published today (March 1) in Bioactive Materials. The U.S. Patent and Trademark ...

Researchers at Cima Universidad de Navarra have discovered that a ribonucleic acid that does not contain information to make proteins (long non-coding RNA) plays a crucial role in signalling and repairing errors in DNA replication during cell division. This finding could lead to the development of new anti-tumour therapies. Scientists have identified an RNA that they named 'lncREST' (long non-coding RNA REplication STress) and uncovered its role in triggering an effective response to the stress induced by rapid cell division. "LncREST localises ...

FOR IMMEDIATE RELEASE   People with cancer have different amounts of a type of repetitive DNA — called Alu elements — than people without cancer. Now, machine learning can measure that from a blood draw. Researchers at the Johns Hopkins Kimmel Cancer Center have used this finding to improve a test that detects cancer early, validating and reproducing the results by starting with a sample size tenfold larger than typical of such types of studies. The research was published Jan. 24 in the journal Science Translational Medicine. Alu ...

As it trundles around an ancient lakebed on Mars, NASA’s Perseverance rover is assembling a one-of-a-kind rock collection. The car-sized explorer is methodically drilling into the Red Planet’s surface and pulling out cores of bedrock that it’s storing in sturdy titanium tubes. Scientists hope to one day return the tubes to Earth and analyze their contents for traces of embedded microbial life.  Since it touched down on the surface of Mars in 2021, the rover has filled 20 of its 43 tubes with cores of bedrock. Now, MIT geologists have remotely determined a crucial property of the rocks collected to date, which will help scientists answer key questions about the planet’s ...

URBANA, Ill. — When broiler chickens are busy fighting the parasitic infection coccidiosis, they can’t absorb nutrients efficiently or put energy toward growth. With consumer sentiment pitted against antimicrobials and other drugs, producers still have some options to ensure optimal growth during inevitable outbreaks. New research from the University of Illinois Urbana-Champaign suggests diet changes might help.  “Vaccines and anticoccidials are the traditional ways to prevent this disease. Nutrition can't replace all of the pharmaceuticals, but it can be supportive in providing care,” said senior study author Ryan Dilger, ...

March 4, 2024- New York City neighborhoods with disrupted community connections, due to traffic, roads, and transport infrastructure, are experiencing an increase in traffic collisions. This increase is seen both in total collisions and for those in which pedestrians or cyclists are injured or killed, according to a new study from Columbia University Mailman School of Public Health. The findings are reported in the journal Environment International. “Despite recent remarkable progress, road safety remains an urgent urban issue in New York and other U.S. cities. It is important to understand how the spatial configuration of the city enhances ...

EDMONTON — A University of Alberta research team has uncovered a new class of drugs with the potential to prevent or treat infections in a future viral outbreak. In the paper, published this week in Nature, the team reports that SARS-CoV-2 — the virus that causes COVID-19 — activates a pathway in cells that stops the production of peroxisomes and interferon, key parts of the normal immune response. The team successfully tested a new class of antiviral drugs that stimulate interferon production to reverse that effect. Tom ...

Switzerland plans to reduce its net carbon emissions to zero by no later than 2050. To achieve this, it will need to drastically reduce its greenhouse gas emissions. In its climate strategy, the Swiss government acknowledges that some of these emissions, particularly in agriculture and industry, are difficult or impossible to avoid. Swiss climate policy therefore envisages actively removing 5 million tonnes of CO2 from the air and permanently storing it underground. By way of comparison, the Intergovernmental ...

(Santa Barbara, Calif.) — You’d probably walk past a chiton without even seeing it. These creatures often look like nothing more than another speck of seaweed on the crusty intertidal rocks. But it sees you. At least, if it’s one of the species with eyes dotting its platemail shell. A team of scientists — led by Rebecca Varney at UC Santa Barbara’s Department of Ecology, Evolution, and Marine Biology (EEMB) — discovered that some of these tough mollusks sport the most recently evolved eyes with a lens. What’s more, the ...

CLEVELAND—Oral cancers and precancerous mouth lesions are considered especially difficult to diagnose early and accurately. For one, biopsies are expensive, invasive, stressful for the patient and can lead to complications. They’re also not feasible if repeated screenings of the same lesion are required. But a team of researchers, led by a clinician scientist at the Case Western Reserve University School of Dental Medicine, has discovered a noninvasive, low-cost test to detect oral cancer, monitor precancerous lesions and determine when a biopsy is warranted. Their findings, published ...

A  New Jersey Gun Violence Research Center study is the first to provide nationally representative data on gun use, storage and violence within Black and American Indian/Alaskan Native (AIAN) families. Both Black and native communities have seen increasingly elevated rates of gun violence victimization, including homicide and suicide, according to the Centers for Disease Control and Prevention. In recent years, minorities have become more represented among new firearm owners. Despite this, research on firearm access, storage and use has focused on samples of white adults. This prevents understanding the access Black and native individuals have to firearms, whether they are stored ...

A new cellphone app developed by physician-scientists at UPMC and the University of Pittsburgh, which uses artificial intelligence (AI) to accurately diagnose ear infections, or acute otitis media (AOM), could help decrease unnecessary antibiotic use in young children, according to new research published today in JAMA Pediatrics. AOM is one of the most common childhood infections for which antibiotics are prescribed but can be difficult to discern from other ear conditions without intensive training. The new AI tool, which makes a diagnosis by assessing ...

About The Study: This study found a negative association between screen time and measures of parent-child talk when children are 12 to 36 months of age. For every additional minute of screen time, children heard fewer adult words, spoke fewer vocalizations, and engaged in fewer back-and-forth interactions. Interventions aiming to promote early use of language should include support to manage screen time.  Authors: Mary E. Brushe, Ph.D., of the University of Western Australia in Adelaide, South Australia, Australia, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2023.6790) Editor’s ...