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Accreditation with commendation awarded to the American College of Chest Physicians

2024-02-29
Glenview, IL– The American College of Chest Physicians® (CHEST) has received accreditation with commendation from the Accreditation Council for Continuing Medical Education (ACCME) and reaccreditation from the Society for Simulation in Healthcare (SSH). This achievement grants CHEST reaccreditation through November 2029 and places the organization in the highest tier of all continuing medical education (CME) providers, including some of the nation’s most prestigious medical schools and professional medical societies. “Receiving reaccreditation with commendation from the ACCME is a real testament to the education team at CHEST including both internal ...

Hahn awarded CZI grant to monitor, manipulate proteins important in nervous system function, neurological disease

Hahn awarded CZI grant to monitor, manipulate proteins important in nervous system function, neurological disease
2024-02-29
CHAPEL HILL, N.C. – The Chan Zuckerberg Initiative (CZI) announced four multi-year Exploratory Cell Networks grants for researchers exploring the frontiers of genomics, cell biology, and synthetic biology by developing new measurement technologies. The projects will be bringing together regional labs in California, the Mid-Atlantic, and the Research Triangle. Klaus Hahn, PhD, the Ronald G. Thurman Distinguished Professor of Pharmacology and member of the UNC Lineberger Comprehensive Cancer Center, will be co-leading a ...

All-light communication network bridges space, air and sea for seamless connectivity

All-light communication network bridges space, air and sea for seamless connectivity
2024-02-29
WASHINGTON — Researchers have developed an all-light communication network that enables seamless connectivity across space, air and underwater environments. The new network design combines different types of light sources to ensure connectivity no matter the environment. “In today’s world, data transmission is critical for communication, navigation, emergency response, research and commercial activities,” said research team leader Yongjin Wang from Nanjing University of Posts and Telecommunications and ...

Parents, wealth, race drive girls’ chances to play sports

2024-02-29
COLUMBUS, Ohio – The likelihood that a girl will participate in high school sports in the United States is driven not so much by individual choice, new research suggests. Instead, decisions made by parents, the wealth of one’s family and community, and racial dynamics matter.   By combining interviews with elite college athletes and analysis of data on over 4,000 high school girls, researchers found that socioeconomic status – of families and the school districts in which they live ...

Study sheds light on how neurotransmitter receptors transport calcium, a process linked with origins of neurological disease

2024-02-29
A new study from a team of McGill University and Vanderbilt University researchers is shedding light on our understanding of the molecular origins of some forms of autism and intellectual disability. For the first time, researchers were able to successfully capture atomic resolution images of the fast-moving ionotropic glutamate receptor (iGluR) as it transports calcium. iGluRs and their ability to transport calcium are vitally important for many brain functions such as vision or other information coming from sensory organs. Calcium also brings about changes in the signalling capacity of iGluRs ...

Artificial intelligence reveals prostate cancer is not just one disease

2024-02-29
Artificial Intelligence has helped scientists reveal a new form of aggressive prostate cancer which could revolutionise how the disease is diagnosed and treated in the future.  A Cancer Research UK-funded study published today, 29 February 2024, reveals that prostate cancer, which affects one in eight men in their lifetime, includes two different subtypes termed evotypes.  The discovery was made by an international team led by the University of Oxford, and the University of Manchester, who applied AI (artificial intelligence) on data from DNA to identify two different subtypes affecting the prostate.   The team hope their findings could save thousands ...

New type of stem cells contains potential for knee cartilage regeneration in arthritic mice

New type of stem cells contains potential for knee cartilage regeneration in arthritic mice
2024-02-29
Osteoarthritis (OA) is a debilitating joint disease which affects over 500 million people worldwide, with trends increasing as populations age. OA is caused by progressive, irreversible degeneration of joint cartilage, leading to pain, swelling and immobility in the affected joint. Current therapies focus on symptom relief but cannot restore degenerated cartilage. A potentially alternative treatment is the regeneration of cartilage from stem cells. Importantly, not all types of stem cells can make cartilage and earlier clinical trials with mesenchymal stem or stromal cells (MSCs) obtained did not convincingly show that MSCs make new cartilage when given to OA patients. In search for the ...

Becoming human: An ancient genome perspective

Becoming human: An ancient genome perspective
2024-02-29
Writing a commentary in the 50th anniversary issue of Cell, FU Qiaomei and E. Andrew Bennett, both of the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences, explored the contribution of paleogenomics to our understanding of the evolution of modern humans. Given her numerous contributions to the field of human evolution through the analysis of both archaic and early modern human genomes, Prof. FU was invited by the journal Cell to write a commentary reviewing what we have learned about the evolution ...

Extreme weather events tied to increased mortality and emergency department activity

2024-02-29
Climate change is increasing the frequency and intensity of severe weather events, which may particularly endanger vulnerable populations such as the elderly. Researchers from Mass General Brigham and colleagues examined how weather disasters between 2011 and 2016 influenced healthcare delivery and mortality among Medicare beneficiaries in affected counties, finding that one week after major weather events, emergency department (ED) use and mortality remained elevated by 1.22% and 1.4%, respectively, from pre-disaster ...

Bottlenecks and beehives: how an invasive bee colony defied genetic expectations

Bottlenecks and beehives: how an invasive bee colony defied genetic expectations
2024-02-29
For more than a decade, invasive Asian honeybees have defied evolutionary expectations and established a thriving population in North Queensland, much to the annoyance of the honey industry and biosecurity officials. Research published today in Current Biology has shown the species, Apis cerana, has overcome what is known as a genetic bottleneck to grow from a single swarm into a population of more than 10,000 colonies over a 10,000 square kilometre area – which is about the size of Greater Sydney. Co-lead author Dr Rosalyn Gloag from the University of Sydney School of Life and Environmental Sciences said: “Our study of this bee population shows that some species can ...

Climate: 2023 – 24 El Niño likely to cause record-breaking average temperatures in some areas

2024-02-29
Several areas of the globe — including the Bay of Bengal, the Philippines, and the Caribbean Sea — are likely to experience record-breaking average surface air temperatures in the year period up to June 2024 as a result of the ongoing El Niño phenomenon. The modelling results, published in Scientific Reports, also suggest that there is an estimated 90 percent chance of record-breaking global mean surface temperatures occurring over the same period under a moderate or strong El Niño scenario. The El Niño-Southern Oscillation, centred ...

Disparities in patient portal use among adults with chronic conditions

2024-02-29
About The Study: This study of 536 participants identified changes in patient portal use over time and highlighted populations that had lower access to health information. The COVID-19 pandemic was associated with an increase in portal use. Sociodemographic disparities by sex and age were reduced, although disparities by health literacy widened. A brief validated health literacy measure may serve as a useful digital literacy screening tool to identify patients who need further support.  Authors: Esther Yoon, Ph.D., M.P.H., M.S., of Northwestern University in Chicago, is the corresponding ...

Factors associated with racial and ethnic disparities in locally advanced rectal cancer outcomes

2024-02-29
About The Study: The findings of this study of 34,500 patients suggest that racial and ethnic disparities in locally advanced rectal cancer treatment outcomes may be multifactorial, with an independent association with non-Hispanic Black race, suggesting unidentified biological variables or social determinants of health that warrant exploration.  Authors: Sanjeevani Arora, Ph.D., and Shannon M. Lynch, Ph.D., M.P.H., of the Fox Chase Cancer Center in Philadelphia, are the corresponding authors.  To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jamanetworkopen.2024.0044) Editor’s ...

CZI announces multi-institutional collaborations for tech to better understand cells

2024-02-29
Today, the Chan Zuckerberg Initiative (CZI) announced four multi-year grants that will bring together regional labs in California, the Mid-Atlantic, and the Research Triangle in North Carolina to explore the frontiers of genomics, cell biology, and synthetic biology by developing new measurement technologies. These projects will focus on developing technologies to engineer cell and tissue models, exploring cellular responses to genetic and environmental stressors, understanding RNA's role in metabolism, and more.  “To unravel the mysteries of the cell, we need new technologies, and the Exploratory Cell Networks grants support early-stage ...

Researchers uncover key therapeutic target involved in diabetic atherosclerosis

2024-02-29
Diabetes accelerates the development of atherosclerosis, increasing the incidence of cardiovascular events. In atherosclerosis, immune cells called macrophages release molecules such as chemokines and cytokines, causing inflammation and leading to arterial plaque formation. However, significant gaps persist in understanding the exact molecular mechanisms controlling this increased inflammatory response in individuals with diabetes. In a new, preclinical study, researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, identified a long non-coding RNA (lncRNA) sequence that could help them unravel the ...

Scripps Research scientists reveal how first cells could have formed on Earth

Scripps Research scientists reveal how first cells could have formed on Earth
2024-02-29
LA JOLLA, CA—Roughly 4 billion years ago, Earth was developing conditions suitable for life. Origin-of-life scientists often wonder if the type of chemistry found on the early Earth was similar to what life requires today. They know that spherical collections of fats, called protocells, were the precursor to cells during this emergence of life. But how did simple protocells first arise and diversify to eventually lead to life on Earth? Now, Scripps Research scientists have discovered one plausible pathway for how protocells may have first formed and chemically ...

EcoFABs could lead to better bioenergy crops

EcoFABs could lead to better bioenergy crops
2024-02-29
– By Will Ferguson A greater understanding of how plants and microbes work together to store vast amounts of atmospheric carbon in the soil will help in the design of better bioenergy crops for the fight against climate change.  Deciphering the mechanics of this mutually beneficial relationship is challenging, however, as conditions in nature are extremely difficult for scientists to replicate in the laboratory. To address this challenge, researchers at Lawrence Berkeley National Laboratory (Berkeley Lab) created fabricated ecosystems or EcoFABs.  In a new paper in Science Advances, they ...

Digital Science announces Catalyst Grant winners, supporting AI-based innovations to benefit research

Digital Science announces Catalyst Grant winners, supporting AI-based innovations to benefit research
2024-02-29
Digital Science has awarded two new Catalyst Grants of £25,000 each to innovative AI-based technology ideas aimed at advancing global research. The winners will use the funding to develop their ideas, which include using AI to alleviate the burden on researchers of applying for research funding, and to predict research impact. The winning applications from Digital Science’s 2023 Catalyst Grant round announced today are: Atom – Tomer du Sautoy (co-founder and CEO) and Hamilton Evans (co-founder and ...

Targeting seed microbes to improve seed resilience

Targeting seed microbes to improve seed resilience
2024-02-29
Fonio (Digitaria exilis), a type of millet, is the oldest indigenous crop in West Africa and one of the fastest maturing cereals. Despite its low yield, the combination of quick maturation and drought tolerance and its ability to thrive in poor soils make it a useful model for understanding how cereals can adapt to future climate change conditions. Nutritionally, fonio is comparable to other millets, says KAUST researcher Naheed Tabassum, but yields are much lower than the major cereal crops rice, maize and wheat. Tabassum believes fonio could complement staple crops amid climate change and desertification ...

Astronomers discover heavy elements after bright gamma-ray burst from neutron star merger

Astronomers discover heavy elements after bright gamma-ray burst from neutron star merger
2024-02-29
An international team of astronomers — including Clemson University astrophysicist Dieter Hartmann — obtained observational evidence for the creation of rare heavy elements in the aftermath of a cataclysmic explosion triggered by the merger of two neutron stars. The massive explosion unleashed a gamma-ray burst, GRB230307A, the second brightest in 50 years of observations and about 1,000 times brighter than a typical gamma-ray burst. GRB230307A was first detected by NASA’s Fermi Gamma-Ray Space Telescope on March 7, 2023. Using multiple space- and ground-based ...

USTC reveals molecular mechanism of transmembrane bilirubin transport by human ABCC2 transporter

USTC reveals molecular mechanism of transmembrane bilirubin transport by human ABCC2 transporter
2024-02-29
The metabolic process of bilirubin has been a focus in medical research since the abnormal accumulation of bilirubin has been found to be associated with a variety of diseases. Bilirubin is a substance produced by the breakdown of aging or damaged red blood cells, and its effective removal is essential for human health.  A research team led by Prof. CHEN Yuxing and Prof. ZHOU Congzhao from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences has revealed the three-dimensional structure and working mechanism of the human bilirubin transporter ABCC2. The study was published ...

USTC realizes durable CO2 conversion in proton-exchange membrane system

USTC realizes durable CO2 conversion in proton-exchange membrane system
2024-02-29
The metabolic process of bilirubin has been a focus in medical research since the abnormal accumulation of bilirubin has been found to be associated with a variety of diseases. Bilirubin is a substance produced by the breakdown of aging or damaged red blood cells, and its effective removal is essential for human health.  A research team led by Prof. CHEN Yuxing and Prof. ZHOU Congzhao from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences has revealed ...

A new plant’s name that tells a story

A new plant’s name that tells a story
2024-02-29
A new species and genus of fairy lantern, tiny glass-like white plants that feed on fungi, has been discovered in Japan. In the country renowned for its extensive flora research, the discovery of a new plant genus is extremely rare and has not occurred in almost 100 years. Fairy lanterns, or Thismiaceae as they are known to botany, are very unusual plants found mainly in tropical but also in subtropical and temperate regions. First of all, they are not green and do not engage in photosynthesis, but rather feed on fungal mycelia in the ground. As a consequence, they are often hidden under fallen leaves and only for a brief period produce above-ground flowers that look like glasswork. The ...

Noteworthy studies to be presented at the 2024 Multidisciplinary Head & Neck Cancers Symposium

2024-02-29
PHOENIX, February 29, 2024 — Research on patient-centered treatment of head and neck cancers will be presented at the 2024 Multidisciplinary Head and Neck Cancers Symposium, which takes place in Phoenix and online today through March 2. Media registration is available via our press kit, and general registration is available via the meeting website. Seven high-impact studies recommended by symposium leadership for media are noted below. All abstracts are available online. Experts are available to provide outside commentary and perspective on research at the meeting; ...

Turbocharging CRISPR to understand how the immune system fights cancer

2024-02-29
Over the past two decades, the immune system has attracted increasing attention for its role in fighting cancer. As researchers have learned more and more about the cancer-immune system interplay, several antitumor immunotherapies have become FDA-approved and are now regularly used to treat multiple cancer types. Yet despite these advances, much remains unknown about how the immune system fights cancer — and about immunity in general, said Martin LaFleur, a postdoctoral fellow in the laboratory of Arlene ...
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