TUCSON, Arizona — The results of a clinical trial led by researchers at the University of Arizona Health Sciences and published in the Journal of Clinical Oncology showed that chemotherapy combining three different types of drugs did not improve overall survival for patients with advanced stage, inoperable biliary tract cancers. “Biliary tract cancer is comparatively rare, but it’s aggressive and spreads fast. Our accrual of more than 450 patients in a little more than two years really shows there is a need for new ways to help people with biliary tract cancer,” ...

PHILADELPHIA (January 16, 2025) – A new Health Affairs Health Policy Brief highlights the detrimental impact of recent state and federal policies that restrict discussions of “divisive concepts,” including structural racism. It warns that these policies undermine efforts to address health inequities and improve population health. “By limiting discussions of structural racism, these policies ignore the historical and environmental factors that shape health outcomes,” said co-author Derek Griffith, PhD,  the Risa Lavizzo-Mourey ...

NYU Tandon, collaborating institutions and industry partners have been awarded nearly $10 million to develop next generation communications technology.   The project, dubbed SALSA (Spectrally Agile Large-Scale Arrays), is funded by the U.S. Department of Commerce's National Telecommunications and Information Administration (NTIA) to advance U.S. leadership in open, secure communications infrastructure. SALSA aims to create advanced wireless systems that operate in the "upper mid-band" spectrum — a region of frequencies relatively ...

In a recently published paper, NASA scientists use nearly 20 years of observations to show that the global water cycle is shifting in unprecedented ways. The majority of those shifts are driven by activities such as agriculture and could have impacts on ecosystems and water management, especially in certain regions. “We established with data assimilation that human intervention in the global water cycle is more significant than we thought,” said Sujay Kumar, a research scientist at NASA’s Goddard Space Flight Center in Greenbelt, Maryland, and a co-author ...

Leo P, a small galaxy and a distant neighbor of the Milky Way, is lighting the way for astronomers to better understand star formation and how a galaxy grows. In a study published in the Astrophysical Journal, a team of researchers led by Kristen McQuinn, a scientist at the Space Telescope Science Institute and an associate professor in the Department of Physics and Astronomy at the Rutgers University-New Brunswick School of Arts and Sciences, has reported finding that Leo P “reignited,” reactivating during a significant period on the timeline of the universe, producing stars when many other small galaxies didn’t.  By ...

A team of astronomers led by University of Arizona researcher Catherine Fielder has obtained the most detailed images of a small galaxy and its surroundings, revealing features typically associated with much larger galaxies. The observations provide a rare, elusive glimpse into how small galaxies form and evolve, suggesting that the mechanisms fueling galaxy growth may be more universal than previously thought. Fielder presented the findings at the 245th meeting of the American Astronomical Society in National Harbor, Maryland, during a press briefing ...

Carbon capture, or the isolation and removal of carbon dioxide from the atmosphere during industrial processes like cement mixing or steel production, is widely regarded as a key component of fighting climate change. Existing carbon capture technologies, such as amine scrubbing, are hard to deploy because they require significant energy to operate and involve corrosive compounds.  As a promising alternative, researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed carbon capture systems that use molecules called ...

The University of Rochester’s Laboratory for Laser Energetics (LLE) has been awarded a $2.25 million grant over three years from the US Department of Energy’s Office of Fusion Energy Sciences. This funding establishes the Inertial Fusion Energy Science and Technology Accelerated Research (IFE-STAR) ecosystem that brings together academia, national laboratories, and the private sector to develop a clean, safe, and virtually limitless energy source, built on US leadership in inertial fusion. Inertial ...

For the first time ever, a complex sense of touch for individuals living with spinal cord injuries is a step closer to reality. A new study published in Science, paves the way for complex touch sensation through brain stimulation, whilst using an extracorporeal bionic limb, that is attached to a chair or wheelchair. The researchers, who are all part of the US-based Cortical Bionics Research Group, have discovered a unique method for encoding natural touch sensations of the hand via specific microstimulation patterns in implantable electrodes in the brain. This allows individuals with spinal cord injuries ...

A novel field experiment in Austria reveals that compounding climate conditions – namely drought, warming, and elevated atmospheric carbon dioxide (CO2 ) – could fundamentally reshape how water moves through soils in temperate grasslands. The findings provide new insights into post-drought soil water flow, in particular. Soil water, though a minuscule fraction of Earth's total water resources, plays a critical role in sustaining terrestrial life on Earth by regulating biogeochemical cycles, surface energy balance, and plant productivity. Soils also govern ...

Severe droughts are becoming hotter, longer, and increasingly devastating to ecosystems as climate change accelerates, according to a new study, which reports that temperate grasslands, including in parts of the United States, are facing the worst effects. The findings provide a global quantitative understanding of multiyear droughts (MYDs) – prolonged events lasting years or decades – and offer a benchmark for understanding their global trends and impacts. As droughts become more frequent ...

Seven Australopithecus specimens uncovered at the Sterkfontein fossil site in South Africa were herbivorous hominins who did not eat substantial amounts of meat, according to a new study by Tina Lüdecke and colleagues. Lüdecke et al. analyzed organic nitrogen and carbonate carbon isotopes extracted from tooth enamel in the fossil specimens to determine the hominin diets. Some researchers have hypothesized that the incorporation of animal-based foods in early hominin diets led to increased brain size, smaller gut size ...

Guided by a multimodal generative language model called ESM3, Thomas Hayes and colleagues generated and synthesized a previously unknown bright fluorescent protein, with a genetic sequence so different from known fluorescent proteins that the researchers say its creation is equivalent to ESM3 simulating 500 million years of biological evolution. The model could provide a new way to “search” the space of protein possibilities with an eye to better understanding how naturally evolved proteins work, as well as developing novel proteins for uses in medicine, environmental remediation, and a host of other applications. ESM3 can reason over protein ...

You can probably complete an amazing number of tasks with your hands without looking at them. But if you put on gloves that muffle your sense of touch, many of those simple tasks become frustrating. Take away proprioception — your ability to sense your body’s relative position and movement — and you might even end up breaking an object or injuring yourself. “Most people don’t realize how often they rely on touch instead of vision — typing, walking, picking up a flimsy cup of water,” said Charles Greenspon, PhD, a neuroscientist at the University of Chicago. “If you can’t feel, you have ...

EVANSTON, Il. --- In a remarkable feat of chemistry, a Northwestern University-led research team has developed the first two-dimensional (2D) mechanically interlocked material. Resembling the interlocking links in chainmail, the nanoscale material exhibits exceptional flexibility and strength. With further work, it holds promise for use in high-performance, light-weight body armor and other uses that demand lightweight, flexible and tough materials. Publishing on Friday (Jan. 17) in the journal ...

Increasingly common since 1980, persistent multi-year droughts will continue to advance with the warming climate, warns a study from the Swiss Federal Institute for Forest, Snow, and Landscape Research (WSL), with Professor Francesca Pellicciotti from the Institute of Science and Technology Austria (ISTA) participating. This publicly available forty-year global quantitative inventory, now published in Science, seeks to inform policy regarding the environmental impact of human-induced climate change. It also detected previously ‘overlooked’ events. Fifteen years of a persistent, devastating megadrought—the longest lasting in a thousand years—have nearly dried out ...

When we think about the immune system, we usually associate it with fighting infections. However, a study published in Science by the Champalimaud Foundation reveals a surprising new role. During periods of low energy—such as intermittent fasting or exercise—immune cells step in to regulate blood sugar levels, acting as the “postman” in a previously unknown three-way conversation between the nervous, immune and hormonal systems. These findings open up new approaches for managing conditions like diabetes, obesity, and cancer. Rethinking the Immune ...

The trick to creating a better quantum sensor? Just give it a little squeeze. For the first time ever, scientists have used a technique called “quantum squeezing” to improve the gas sensing performance of devices known as optical frequency comb lasers. These ultra-precise sensors are like fingerprint scanners for molecules of gas. Scientists have used them to spot methane leaks in the air above oil and gas operations and signs of COVID-19 infections in breath samples from humans. Now, in a series of lab experiments, researchers have laid out a path for making those kinds of measurements even more sensitive and faster—doubling the speed of ...

New research co-led by the University of Maryland reveals that drought and increased temperatures in a CO2-rich climate can dramatically alter how grasslands use and move water. The study provides the first experimental demonstration of the potential impacts of climate change on water movement through grassland ecosystems, which make up nearly 40% of Earth’s land area and play a critical role in Earth’s water cycle. The study appears in the January 17, 2025, issue of the journal Science. “If we want to predict the effects of climate change ...

EMBARGO: THIST CONTENT IS UNDER EMBARGO UNTIL 2 PM U.S. EASTERN STANDARD TIME ON JANUARY 16, 2025. INTERESTED MEDIA MAY RECIVE A PREVIEW COPY OF THE JOURNAL ARTICLE IN ADVANCE OF THAT DATE OR CONDUCT INTERVIEWS, BUT THE INFORMATION MAY NOT BE PUBLISHED, BROADCAST, OR POSTED ONLINE UNTIL AFTER THE RELEASE WINDOW.  Researchers at Colorado State University and their partners have developed an adhesive polymer that is stronger than current commercially available options while also being biodegradable ...

The National Institute of Mental Health has awarded a significant grant of $1.5 million to Jianyang Du, PhD, of the University of Tennessee Health Science Center, for a research study aimed at uncovering the cellular and molecular mechanisms that lead to neurological disorders caused by long COVID-19. Dr. Du is an associate professor at the College of Medicine in the Department of Anatomy and Neurobiology. Colleen Jonsson, PhD, director of the UT Health Science Center Regional Biocontainment Laboratory and professor in the Department of Microbiology, is co-investigator on the grant, and Kun Li, PhD, assistant ...

A University of Massachusetts Amherst-Ernest Pharmaceuticals team of scientists has made “exciting,” patient-friendly advances in developing a non-toxic bacterial therapy, BacID, to deliver cancer-fighting drugs directly into tumors. This emerging technology holds promise for very safe and more effective treatment of cancers with high mortality rates, including liver, ovarian and metastatic breast cancer. Clinical trials with participating cancer patients are estimated to begin in 2027. “This is exciting because we now have all the critical pieces for getting an effective bacterial ...

Siblings share a unique bond built from shared memories, family rituals and the occasional argument. But ask almost anyone with a brother or sister and you’ll likely find a longstanding debate: who’s the favorite? New research from BYU sheds some light on that playful rivalry, revealing how parents might subtly show favoritism based on birth order, personality and gender. The study, conducted by BYU School of Family Life professor Alex Jensen, found that younger siblings generally receive more favorable ...

A mussel bed along Northern California’s Dillon Beach is as healthy and biodiverse as it was about 80 years ago, when two young students surveyed it shortly before Pearl Harbor was attacked and one was sent to fight in World War II.  Their unpublished, typewritten manuscript sat in the UC Davis Bodega Marine Laboratory’s library for years until UC Davis scientists found it and decided to resurvey the exact same mussel bed with the old paper’s meticulous photos and maps directing their way. The new findings, published in the journal Scientific Reports, document ...

ATLANTA, January 16, 2025 — The American Cancer Society (ACS) today released Cancer Statistics, 2025, the organization’s annual report on cancer facts and trends. The new findings show the cancer mortality rate declined by 34% from 1991 to 2022 in the United States, averting approximately 4.5 million deaths. However, this steady progress is jeopardized by increasing incidence for many cancer types, especially among women and younger adults, shifting the burden of disease. For example, incidence rates in women 50-64 years of age have surpassed those in ...