About The Study: This systematic review and meta-analysis found inverse associations and a dose-response association between fluoride measurements in urine and drinking water and children’s IQ across the large multi-country epidemiological literature. There were limited data and uncertainty in the dose-response association between fluoride exposure and children’s IQ when fluoride exposure was estimated by drinking water alone at concentrations less than 1.5 mg/L. These findings may inform future comprehensive public health risk-benefit assessments of fluoride exposures. Corresponding ...

About The Study: This cross-sectional study’s analysis underscores a public health crisis of substance use disorder. The prevalence of substance use disorder surged during the COVID-19 pandemic, yet the receipt of treatment declined initially as health care services were disrupted. Treatment rates began to recover in 2022, likely due to reopened treatment programs and increased telehealth use. Corresponding Author: To contact the corresponding author, Milap C. Nahata, PharmD, MS, email nahata.1@osu.edu. To access ...

Embargoed for release: Monday, Jan. 6, 2025, 11:00 AM ET Key points: Less than 0.1% of U.S. adolescents were transgender and gender diverse (TGD) and prescribed puberty blockers or gender-affirming hormones in a study of private insurance claims representing 5.1 million patients ages eight to 17. No TGD patients under age 12 received hormones. According to the researchers, the findings counter a growing concern among policymakers that gender-affirming care is frequently over-prescribed to children. Boston, MA—Puberty blockers and gender-affirming hormones are rarely prescribed to U.S. transgender and gender diverse (TGD) adolescents, according to a new study from researchers ...

About The Study: This longitudinal cohort study suggests that early-life infection burden may continue throughout childhood and is associated with later antibiotic treatments independent of social and environmental risk factors. These findings are important for prognosis and follow-up of children experiencing a high burden of common infections in early life.  Corresponding Author: To contact the corresponding author, Nicklas Brustad, MD, PhD, email nicklas.brustad@dbac.dk. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.53284) Editor’s ...

Key Takeaways: A new study in JAMA Internal Medicine led by the Harvard Pilgrim Health Care Institute examined whether doxycycline post-exposure prophylaxis (doxyPEP) was associated with declines in bacterial sexually transmitted infections in routine care. The study represents the largest cohort of doxyPEP recipients reported globally to date. Findings showed doxyPEP was associated with a 79% reduction in chlamydia, 80% reduction in syphilis, and 12% reduction in gonorrhea. Boston, MA — A new study has found that rates of chlamydia and syphilis plummet among people prescribed doxycycline for sexually transmitted ...

Billions of years ago, in the frigid outer reaches of our solar system, two icy worlds collided. Rather than destroying each other in a cosmic catastrophe, they spun together like a celestial snowman, finally separating while remaining forever linked in orbit. This is how Pluto and its largest moon, Charon, originated, according to a new University of Arizona study that challenges decades of scientific assumptions. A study led by Adeene Denton, a NASA postdoctoral fellow who conducted the research at the U of A Lunar and Planetary Laboratory, has revealed this unexpected "kiss and capture" mechanism, which could help scientists better ...

Introducing Annotatability—a powerful new framework to address a major challenge in biological research by examining how artificial neural networks learn to label genomic data. Genomic datasets often contain vast amounts of annotated samples, but many of these samples are annotated either incorrectly or ambiguously. Borrowing from recent advances in the fields of natural language processing and computer vision, the team used artificial neural networks (ANNs) in a non-conventional way: instead of merely using the ANNs to make predictions, the group inspected the difficulty with which they learned to label ...

Tropical forests, often referred to as the "lungs of the Earth," are essential for sustaining life on our planet. They provide clean air, water, and unparalleled biodiversity. While deforestation due to slash-and-burn agriculture, mining, and logging remains the most recognized threat, less visible but equally dangerous forces are at work. A new study reveals that nutrient enrichment – driven by human activities such as agriculture and fossil fuel combustion – poses a significant risk to the delicate dynamics of tropical forests. The research, conducted by an international team of scientists ...

Landfill gas, a mixture of gases produced when garbage breaks down within landfills, contains unwanted traces of siloxane compounds, which are chemical structures containing silicon and oxygen bonds and are found in various products like cosmetics and cleaning agents. These compounds can damage the equipment used to generate energy from landfill gas. In new research published in Environmental Progress & Sustainable Energy, investigators have identified low-cost adsorbents for siloxane removal from landfill gas. The research highlights the potential of ...

Weill Cornell Medicine has received a five-year, $2.3 million grant from the Centers for Disease Control and Prevention to improve equitable access to care, quality of life and survival outcomes for young people with all stages of breast cancer. The grant will enable Weill Cornell Medicine to enhance care coordination for patients and caregivers to optimize support of physical, mental, emotional, social and spiritual needs, while offering culturally relevant resources and targeted interventions. The initiative ...

BINGHAMTON, N.Y. -- Have you ever noticed a swath of similar business news stories about a particular topic during a Google search, all of them appearing to be reported by different news outlets? Why might a story on a news site in New York be so similar to one from a site in, for example, Wisconsin? It’s likely because the same media company owns them — and it’s become more commonplace nationwide as news outlets grapple with dwindling resources. A new study co-authored by Flora Sun, assistant professor of accounting at Binghamton University’s School of Management, ...

Imagine you’re at a dinner party, but you can’t smell the food cooking or hear the dinner bell. Sounds like a dream, right? What if it wasn’t? “When we experience the world and interact with people, we use all our senses,” Cold Spring Harbor Laboratory Professor Stephen Shea says. “That’s true for animals and humans.” However, that’s not always the case in developmental disorders like autism. These conditions can affect how the brain processes incoming information, making it difficult to interpret the social cues that drive conversations, dates, and other ...

2024 was another year of record-breaking temperatures, driving the global water cycle to new climate extremes and contributing to ferocious floods and crippling droughts, a new report led by The Australian National University (ANU) shows.  The 2024 Global Water Monitor Report, involving an international team of researchers and led by ANU Professor Albert van Dijk, found rising temperatures are changing the way water moves around the planet, “wreaking havoc” on the water cycle.  “Rising ...

COLUMBUS, Ohio – A new study used acoustic sensors that detect the sound of gunfire to show how often children in one Chicago neighborhood are exposed to gunshots while walking to and from school.   Results showed that nearly two-thirds of schools in the Englewood neighborhood of Chicago had at least one gun incident within 400 meters (about one-quarter mile) of where children were walking home during the 2021-22 school year.   These findings suggest a need to redefine federal definitions of school gun violence to include indirect forms of violence that take place near schools, not only on school grounds, in order to more appropriately ...

Since the 1950s, scientists have used radio waves to uncover the molecular “fingerprints” of unknown materials, aiding in tasks as varied as scanning the human body with MRI machines and detecting explosives at airports. These methods, however, rely on signals averaged from trillions of atoms, making it impossible to detect tiny variations between individual molecules. Such limitations hinder applications in fields like protein research, where small differences in shape control functionality and can determine the difference between health and disease. Sub-Atomic Insights Now, engineers at the University of Pennsylvania ...

In recent years treatment with powerful biologic and targeted synthetic therapies has changed the landscape for arthritis, but currently finding the right treatment for each person is a matter of trial and error. Only a proportion of patients with inflammatory arthritis respond to each expensive therapy, which results in unnecessary treatment and a long and often frustrating journey for patients, not to mention significant cost to the NHS. University of Birmingham researchers have just been awarded £3.5 million funding from Johnson & Johnson to investigate ...

By Rachel Tompa, Ph.D Your blood is a delicate mixture. Researchers and clinicians often use blood to learn what’s going on inside our bodies, in part because siphoning off a tube of blood is easier and less painful than taking biopsies of an internal organ.  But in some cases, it turns out that blood can be very different outside our bodies. When it comes to certain emerging research techniques, the clock starts ticking as soon as your blood hits the tube. As little as six to eight hours later, some aspects of your blood’s ...

VANCOUVER, Wash. – Some of the most productive apple regions in America are facing big challenges from a changing climate, according to a Washington State University study. Researchers analyzed over 40 years of climate conditions that impact the growth cycle of apple trees from bud break and flowering through fruit development, maturation and color development. While many growing areas are facing increased climate risks, the top three largest apple producing counties in the U.S. were among the most impacted: Yakima in Washington, Kent in Michigan and Wayne ...

An up-close look at how patients respond to the drug at different times and doses adds nuance to a recent finding that Paxlovid does not work for long Covid.   An extended course of Paxlovid appears to help some patients with long Covid, according to a case series by UC San Francisco researchers that suggests this treatment option holds promise for some of those struggling with debilitating symptoms.  These results are at odds with recent research that has failed to show the antiviral can alleviate persistent symptoms of the disease. The authors said more study is needed to find out which patients may benefit from the drug and how long it should be given. The ...

From photographs of decimated buildings to military and civilian casualty counts to narratives of suffering, news media bring information about foreign conflicts to American audiences. But does this coverage actually affect public opinion about whether and how the United States should be involved in a conflict? Does it influence what Americans think about the U.S. providing military, diplomatic, and economic aid to foreign nations? A new paper from researchers at the Annenberg Public Policy Center (APPC) of the University of Pennsylvania examines these questions and finds that media coverage of civilian casualties increases public support for U.S. involvement in conflicts by evoking empathy ...

In the Arctic, the old, multiyear ice is increasingly melting, dramatically reducing the frequency and size of pressure ridges. These ridges are created when ice floes press against each other and become stacked, and are a characteristic feature of Arctic sea ice, an obstacle for shipping, but also an essential component of the ecosystem. In a recently released study in the journal Nature Climate Change, experts from the Alfred Wegener Institute report on this trend and analyse observational data from three decades of aerial surveys. Satellite data from the last three decades documents the dramatic changes in Arctic sea ice due to climate change: the area covered in ice in summer ...

Annual health checkups regularly include urine tests that serve several purposes, including checking for symptoms of kidney disease. The presence of albumin in the urine is one indicator as is glomerular filtration rate. In diabetic nephropathy, albuminuria first appears, leading to excessive filtration and eventually a decrease in GFR. In the elderly, however, excessive filtration cannot be detected due to age-related GFR decline. To accurately assess GFR, Osaka Metropolitan University researchers have come up with ...

A new set of guidelines has been developed to assist with the diagnosis and expert management of serious blood cancers in pregnancy. About 12.5 pregnancies per 100,000 are affected by blood cancers such as acute leukaemia and aggressive lymphomas, and their incidence has been rising. Between 1994 and 2013, they increased by 2.7 per cent a year, due to factors including women having children later, improved diagnostic techniques, and increased health system engagement. An Australian working group has now published a new position statement in the latest edition of The Lancet Haematology, based on current evidence and expert consensus. It ...

Biologists at Indiana University Bloomington have shown that the surfaces of plant leaves are coated with a diverse array of RNA molecules. The finding suggests that the RNA present on the leaf surface may play a role in shaping the microbial communities that inhabit them, potentially influencing plant health and interactions within their environment, according to a new study. The study, Diverse plant RNAs coat Arabidopsis leaves and are distinct from apoplastic RNAs, was published Jan. 3, 2025 in the Proceedings of the National Academy of Sciences. The first authors are Lucía ...

Urban sprawl is not just unsightly. It could also be impeding intergenerational mobility for low-income residents and reinforcing racial inequality, according to a series of recent studies led by a University of Utah geographer. One analysis of tract-level Census data co-authored with a former economics graduate student in the U’s College of Social & Behavioral Science found that people who grew up in high-sprawl neighborhoods have less earning potential than those who grew in denser neighborhoods. “For adults, jobs are harder to access in more sprawling neighborhoods,” said Kelsey Carlston, now an assistant professor of economics at Gonzaga University. “If we ...