Despite awe-inspiring diversity, nearly every lifeform – from bacteria to blue whales – shares the same genetic code. How and when this code came about has been the subject of much scientific controversy.  Taking a fresh approach at an old problem, Sawsan Wehbi, a doctoral student in the Genetics Graduate Interdisciplinary Program at the University of Arizona, discovered strong evidence that the textbook version of how the universal genetic code evolved needs revision. Wehbi is the first author of a study published in the journal PNAS suggesting the order with which amino acids – the code's building blocks –  were recruited is at odds with ...

A program designed to prepare future teachers and K-12 students for a lifetime of innovation recently received a $572,890 boost from the National Science Foundation. The ChangeMaker K-12 program, designed by faculty from the University of Louisiana at Lafayette’s College of Education & Human Development, received a second round of grant funding to expand the teacher prep program to other universities. The new partners are the University of Louisiana Monroe, Louisiana Tech University and the University of Hawaii at Manoa. The project is led by Dr. Doug Williams, director of UL Lafayette’s Center for Innovative Learning and Assessment Technologies, along with Dr. Aimee Barber, ...

A team of researchers at USC and the University of Utah has received a $2.7 million grant from the National Institutes of Health to map out how an incurable eye disease affects the wiring that powers vision in the eye, in hopes of discovering ways to slow or prevent blindness. Retinitis pigmentosa (RP) is a progressive disease with four known stages that affects the retina, the area at the back of the eye where light is turned into electrical signals that the brain processes to produce sight. The research ...

AI will soon receive a dose of empathy with the goal of helping to match people with depression to their best-fit medication. A team led by Farrokh Alemi, a professor in the College of Public Health (CPH), and Kevin Lybarger, an assistant professor in the College of Engineering and Computing (CEC), received $1,049,998 in research funding from the Patient-Centered Outcomes Research Institute (PCORI) to continue their work on developing an AI system that helps patients find the right depression medications. With this funding support, Co-PIs Alemi and Lybarger will hone large language models (LLMs) to address known challenges in ...

CHAMPAIGN, Ill. — The Midwest played a central role in the growth of Black freedom movements in the 20th century. It was a key site for incubating and expanding the ideas of political activist Marcus Garvey, not only in the U.S., but globally, said University of Illinois Urbana-Champaign professor of African American studies and history Erik S. McDuffie. McDuffie examined the influence of Garvey and the importance of the Midwest in the growth of Black internationalism and radicalism in his new book, “The Second Battle for Africa: Garveyism, the U.S. Heartland and Global Black Freedom.” McDuffie ...

In most research labs, the scientists are on the same page about why they’re pursuing a research project. But the Rubin Lab at HHMI's Janelia Research Campus isn’t an ordinary research lab. The lab is examining how aggression affects vision in female fruit flies, but Janelia Senior Group Leader Gerry Rubin doesn’t care too much about the specific answer. Instead, he simply wants to see if the neuroscience research tools that he spent the last decade building are adequate to uncover the underlying mechanisms at play.    Postdoc Katie Schretter, on the other hand, is interested in understanding how neurons in the fly brain ...

HOUSTON, Dec. 12 2024 – A group of ambitious students from the University of Houston and Texas A&M University, identifying as the “Dream Team,” secured third place in the prestigious global Switch Competition. This annual virtual event, sponsored by the Switch Energy Alliance, challenges university students to develop innovative solutions for addressing energy poverty worldwide — a critical issue affecting millions. The team is comprised of Sarah Grace Kimberly and Pranjal Sheth, both senior finance majors at UH, and Nathan Hazlett, a finance graduate student at A&M who previously earned a bachelor’s degree in petroleum engineering. Competing ...

For experiments that require ultra-precise measurements and control over atoms — think two-photon atomic clocks, cold-atom interferometer sensors and quantum gates — lasers are the technology of choice, the more spectrally pure (emitting a single color/frequency), the better. Conventional lab-scale laser technology currently achieves this ultra low-noise, stable light via bulky, costly tabletop systems designed to generate, harness and emit photons within a narrow spectral range. But what if these atomic applications ...

A new analysis published in the journal Science reveals that overfishing has caused populations of chondrichthyan fishes – sharks, rays, and chimaeras – to decline by more than 50 per cent since 1970. To determine the consequences, a team of researchers developed an aquatic Red List Index (RLI) which shows that the risk of extinction for chondrichthyan has increased by 19 per cent. The study also highlights that the overfishing of the largest species in nearshore and pelagic habitats could eliminate up to 22 per cent of ...

Clinicians who completed an American College of Lifestyle Medicine (ACLM) course introducing the foundations of lifestyle medicine and food as medicine reported significant improvements in their knowledge and confidence, as well as increases in how often they practice lifestyle medicine with patients, a research study found. The findings are important because, while lifestyle behavior changes are often the optimal treatment option in clinical practice guidelines for noncommunicable chronic diseases, many clinicians cite their lack of knowledge and training in lifestyle behavior interventions as a barrier. A growing body of evidence supports the ...

An international team of scientists headed by Dr. Lukas Bruder, junior research group leader at the Institute of Physics, University of Freiburg, has succeeded in producing and directly controlling hybrid electron-photon quantum states in helium atoms. To this end, they generated specially prepared, highly intense extreme ultraviolet light pulses using the FERMI free electron laser in Trieste, Italy. The researchers achieved control of the hybrid quantum states using a new laser pulse-shaping technique. Their results have ...

It’s a question that has puzzled thinkers for centuries: Are we humans alone in our pursuit of fairness and the frustration we feel when others get what we want? In recent years, evolutionary psychologists have suggested that we’re not all that special. Animals, from corvids to capuchin monkeys, express what humans might recognize as jealousy when, for example, they are passed over for a sought-after snack. Many argue this is evidence we are not alone in our aversion toward unfairness.  But new research from the University of California, Berkeley, makes the case that humans might be unique after all.  Using data from ...

Researchers at University of California San Diego and collaborating institutions have shed light on the ways that social risks, such as housing or food insecurity, pose barriers to routine cancer screenings. The study, published in JNCI Cancer Spectrum, found that patients experiencing social risks were less likely to receive orders for cancer screenings and even less likely to complete screenings when ordered. The study also found that patients experiencing social risks had higher rates of primary care ...

Editors of academic journals hold an influential position in their field. They have decision-making power over which authors and papers get published, set journal policy, and help shape the trajectory of their discipline. It is also a role in which women are frequently underrepresented. Assistant professor of accounting Sebastian Tideman-Frappart and several colleagues set out to fill a knowledge gap about this issue in the field of management science by tracking gender diversity in world-leading management journals over time. The resulting article – co-authored by Brooke Gazdag, associate professor of management at Kühne Logistics University; Jamie Gloor, assistant professor ...

In a breakthrough study published this week in The Journal of Physiology, researchers at the Marine Mammal Research Program (MMRP) at the University of Hawaiʻi at Manoa's Hawaiʻi Institute of Marine Biology (HIMB) demystify the energetic cost of humpback pregnancy and shed light on the unique vulnerabilities of migratory humpback mothers-to-be. With an arsenal of tools that range from cutting-edge technology to historical whaling records, the research was done in close partnership with Alaska ...

In a Policy Forum, scientists discuss lifeforms composed of mirror-image biological molecules – also known as “mirror life” – and say creation of such lifeforms, which could evade immune mechanisms and predators, warrants careful consideration. The hallmark of mirror organisms is reversed chirality – a feature that would render them resistant to normal forms of biological degradation, making them useful for applications like long-lasting therapies. While these organisms haven’t yet been observed in nature, and the capability to create them is likely at least ...

As its 2024 Breakthrough of The Year, Science has named the development of lenacapavir – a promising new injectable drug that prevents HIV infection. The award also recognizes related work surrounding gaining a new understanding of the structure and function of HIV’s capsid protein. Despite decades of advancements, HIV continues to infect more than a million people annually, with a vaccine remaining elusive. However, a new injectable drug, lenacapavir, offers hope by providing six ...

The 2014-2016 Pacific marine heatwave wiped out more than half – roughly 4 million – of Alaska’s common murre (Uria aalge) seabirds, representing the largest documented vertebrate die-off linked to warming oceans, according to a new study. “Although research on the impacts of global warming on marine birds has clearly suggested major shifts in species’ ranges and abundance, documented changes have been gradual (years to decades),” write the authors. “To our knowledge, this study is the first to show that climate impacts can be swift (1 ...

A genomic study encompassing more than 300 genomes spanning the last 50,000 years has revealed how a single wave of Neandertal gene flow into early modern humans left an indelible mark on human evolution. Among other findings, the study reports that modern humans acquired several Neanderthal genes that ended up being advantageous to our lineage, including those involved in skin pigmentation, immune response, and metabolism. To date, sequencing of Neanderthal and Denisovan genomes has revealed substantial gene flow between these archaic hominins ...

There is no question that the Sun is a temperamental star, as alone this year’s unusually strong solar storms prove. Some of them led to remarkable auroras even at low latitudes. But can our star become even more furious? Evidence of the most violent solar “tantrums” can be found in prehistoric tree trunks and in samples of millennia-old glacial ice. However, from these indirect sources, the frequency of superflares cannot be determined. And direct measurements of the amount of radiation reaching the Earth from the Sun have only been available since the ...

A new analysis of DNA from ancient modern humans (Homo sapiens) in Europe and Asia has determined, more precisely than ever, the time period during which Neanderthals interbred with modern humans, starting about 50,500 years ago and lasting about 7,000 years — until Neanderthals began to disappear. That interbreeding left Eurasians with many genes inherited from our Neanderthal ancestors, which in total make up between 1% and 2% of our genomes today. The genome-based estimate is consistent with archeological evidence that modern humans and Neanderthals lived side-by-side in Eurasia for between 6,000 and 7,000 years. The analysis, which involved present-day human genomes ...

The study of ancient DNA has greatly advanced our knowledge of human evolution, including the discovery of gene flow from Neandertals into the common ancestors of modern humans. Neandertals and modern humans diverged about 500,000 years ago, with Neandertals living in Eurasia for the past 300,000 years. Then, sometime around 40,000 to 60,000 years ago, modern human groups left Africa and spread across Eurasia, encountering Neandertals along the way. As a result, most non-Africans harbor one to two percent ...

LA JOLLA (December 12, 2024)—The decision between scrambled eggs or an apple for breakfast probably won’t make or break your day. However, for your cells, a decision between similar microscopic nutrients could determine their entire identity. If and how nutrient preference impacts cell identity has been a longstanding mystery for scientists—until a team of Salk Institute immunologists revealed a novel framework for the complicated relationship between nutrition and cell identity. The answers came while the researchers ...

After modern humans left Africa, they met and interbred with Neandertals, resulting in around two to three percent Neandertal DNA that can be found in the genomes of all people outside Africa today. However, little is known about the genetics of these first pioneers in Europe and the timing of the Neandertal admixture with non-Africans. A key site in Europe is Zlatý kůň in Czechia, where a complete skull from a single individual who lived around 45,000 years ago was discovered and previously ...

Viruses that infect and kill bacteria, called phages, hold promise as new treatment types for dangerous infections, including strains that have become resistant to antibiotics. Yet, virologists know little about how phages persist in the populations of bacterial cells they infect, hampering the development of phage therapies. Published online December 13 in the journal Science, a new study offers the first evidence that a single bacterial species, the host of a phage, can maintain a diverse community of competing phage species. Led by researchers at NYU Grossman ...