Philadelphia, December 9, 2024 – Researchers from Children’s Hospital of Philadelphia (CHOP) found that transmission of rotavirus vaccine strains in a neonatal intensive care unit (NICU) is rare and without clinical consequences, strongly suggesting that giving the rotavirus vaccine to eligible infants during their hospitalization provides immune benefits that outweigh any risks. The findings, published today in the journal Pediatrics, could serve as the basis for a change in clinical practice. Rotavirus is a virus that infects the lining of the intestines and is typically ...

New guidelines on the diagnosis and management of premature ovarian insufficiency (POI) –  developed by the Centre for Research Excellence in Women’s Health in  Reproductive Life (CRE-WHiRL) at Monash University, and key international women’s health organisations with an international team of experts including women with lived experience – will be published today (TBC) simultaneously in three leading journals. POI is defined as loss of ovarian function before 40 years. This is much earlier than the usual age of menopause; occurring at an average age of 48-51 years in women globally. POI affects approximately 4 per cent ...

Parents who face the heartbreaking loss of their child should get a specific keyworker to support them through bereavement, wherever they are in the country, according to a set of recommendations informed by new research.   In an academic paper published in Archives of Disease in Childhood today, bereaved parents and academic experts from the University of Birmingham, University of Bristol and Birmingham Community Healthcare NHS Foundation Trust have outlined their recommendations for support that all bereaved parents ...

Bucking conventionality, boys in Norway are making early gains in reading English as a second language and even outperforming girls at age 10 and 13 – a new a study of more than one million students suggests. Publishing their findings in the peer-reviewed journal Assessment in Education: Principles, Policy & Practice, experts from the University of Oslo propose the perhaps unexpected results might be explained by online gaming and experiences with other digital technologies such as YouTube – with English being the language of the internet. “Our ...

Chronic pain is an acute and debilitating condition that affects millions of people worldwide. And while pain interventions are available, many people struggle without treatment at all.   Now new research from the University of South Australia shows that adopting a healthy diet can reduce the severity of chronic pain, presenting an easy and accessible way for sufferers to better manage their condition.   Exploring associations between body fat, diet, and pain, researchers found that a greater consumption of foods within the Australian Dietary Guidelines was directly associated with lower levels of body ...

MIAMI, FLORIDA (STRICTLY EMBARGOED UNTIL DEC. 8, 2024, AT 12 NOON EST) – Two clinical trials testing the antibody loncastuximab tesirine (Zynlonta) showed encouraging results in patients with high-risk forms of two blood cancers – follicular lymphoma and marginal zone lymphoma. The findings, led by physician-scientists at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, will be presented at the American Society of Hematology’s 2024 meeting in San Diego. One study, a phase 2 clinical trial led by Juan Alderuccio, M.D., ...

HONG KONG (8 December 2024)—A new vortex electric field with the potential to enhance future electronic, magnetic and optical devices has been observed by researchers from City University of Hong Kong (CityUHK) and local partners. The research, published in Science, is highly valuable as it can upgrade the operation of many devices, including strengthening memory stability and computing speed. With further research, the discovery of the vortex electric field can even later impact the fields of quantum computing, spintronics, and nanotechnology. “Previously, generating a vortex electric field required expensive thin film deposition techniques and complex procedures. However, our ...

Though he doesn’t remember it, Branden Baptiste had his first sickle cell crisis at age 2. Through elementary school, he was in and out of the hospital with pain episodes, not knowing why. As he got older, he learned he had sickle cell disease: His red blood cells were forming sickle shapes and getting stuck in his blood stream, preventing oxygen from reaching his tissues. “From age 12, things skyrocketed,” says Branden, now 20. “I was in the hospital every other month with crises.” He estimates he missed 60 days of school every year. In sixth grade, Branden had to have his left hip replaced ...

SAN DIEGO – A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine’s Abramson Cancer Center. While the approach needs to be assessed in clinical trials, the early research, shared in a press briefing today at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition (Abstract 4), hints at a potentially cost-effective strategy to improve CAR T cell function and cancer-fighting abilities.    CAR T cell therapy is a ...

Today researchers at Memorial Sloan Kettering Cancer Center (MSK) reported results from the first ever clinical trial to show that a high fiber plant based dietary intervention may delay progression to multiple myeloma, a type of rare, incurable blood cancer affecting the bone marrow. The study enrolled 20 participants with a precancerous blood disorder and an elevated body mass index (BMI) at risk for developing multiple myeloma. They received 12 weeks of high fiber plant-based meals and 24 weeks of coaching. Two participants with progressing disease prior to study showed a significant improvement of their disease progression trajectory. Additionally, at one year ...

Just days before his fourth birthday, Santiago was diagnosed with B-cell acute lymphoblastic leukemia (B-ALL), the most common cancer in children.  He began chemotherapy the next day, and the outlook was promising – disease-free survival rates for B-ALL are among the highest for paediatric cancers, at 80 to 85 per cent. However, limited progress has been made over the last 15 years, and relapsed B-ALL remains a leading cause of cancer death among children.  Seeking to explore all options, Santiago’s parents enrolled him in a Children’s Oncology Group clinical trial led by scientists ...

Tokyo, Japan – Researchers from Tokyo Metropolitan University showed that agricultural land preserved around river confluences can help mitigate floods. They make a case for Eco-DRR, an approach that uses existing environmental resources to improve resilience against flooding. Statistical analysis showed that municipalities with agricultural land in areas with high water storage potential suffered fewer floods, with stronger correlation when agricultural land was situated near river confluences. The team hope their findings inform effective land usage.   Climate change has brought ...

In fields ranging from immunology and ecology to economics and thermodynamics, multi-scale complex systems are ubiquitous. They are also notoriously difficult to model. Conventional approaches take either a bottom-up or top-down approach. But in disturbed systems, such as a post-fire forest ecosystem or a society in a pandemic, these unidirectional models can’t capture the interactions between the small-scale behaviors and the system-level properties. SFI External Professor John Harte (UC Berkeley) and his collaborators have worked to resolve this challenge by building a hybrid method that links bottom-up behaviors and top-down causation in a single theory.  Harte et ...

Experts have used magnetic resonance imaging (MRI) to better understand the impact a gluten free diet has on people with coeliac disease, which could be the first step towards finding new ways of treating the condition. The MARCO study – MAgnetic Resonance Imaging in COliac disease – which is published in Clinical Gastroenterology and Hepatology (CGH), was led by experts from the School of Medicine at the University of Nottingham, alongside colleagues at the Quadram Institute. Coeliac disease is a chronic condition affecting around one person in every 100 in the general population. When people with coeliac ...

BIRMINGHAM, Ala. – BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research at the University of Alabama at Birmingham reveals new aspects of BKPyV replication, offering possible drug targets to protect transplanted kidneys.   To better understand BKPyV replication and ways to prevent it, researchers in the UAB  Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their findings contradict a long-held understanding of the molecular events required for BKPyV ...

Irvine, Calif., Dec. 6, 2024 — Recent decades have seen a rapid surge in damages and disruptions caused by flooding. In a commentary article published today in the American Geophysical Union journal Earth’s Future, researchers at the University of California, Irvine and the University of Bristol in the United Kingdom – the latter also executives of U.K. flood risk intelligence firm Fathom – call on scientists to more accurately model these risks and caution against overly dramatized reporting of future risks in the news media.   In the paper, the researchers urge the climate science community to turn ...

Amid all the changes in Earth’s climate, sea ice in the stormy Southern Ocean surrounding Antarctica was, for a long time, an odd exception. The maximum winter sea ice cover remained steady or even increased slightly from the late 1970s through 2015, despite rising global temperatures. That began to change in 2016. Several years of decline led to an all-time record low in 2023, more than five standard deviations below the average from the satellite record. The area of sea ice was 2.2 million square kilometers below the average from ...

Future farmers and leaders in agriculture need to understand and implement technologies that use artificial intelligence. A team of University of Tennessee Institute of Agriculture faculty are working toward creating new curriculum to train the next generation of agriculture students. Led by Hao Gan, assistant professor in the Department of Biosystems Engineering and Soil Science, the team won a four-year grant for $741,102 from the USDA’s National Institute of Food and Agriculture. The project, “Development of a Smart Agricultural Experiential Learning Program for Youth,” will create hands-on curriculum about using drones, ground robots, computer ...

Researchers have developed a novel device that couples magnetic fields and kirigami design principles to remotely control the movement of a flexible dimpled surface, allowing it to manipulate objects without actually grasping them – making it useful for lifting and moving items such as fragile objects, gels or liquids. The technology has potential for use in confined spaces, where robotic arms or similar tools aren’t an option. “We were trying to address two challenges here,” says Jie Yin, co-corresponding ...

Fukuoka, Japan – Researchers at Kyushu University have revealed how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer modeling, the researchers showed that the folding and movement of DNA, as well as the accumulation of certain proteins, changes depending on whether a gene is active or inactive. The study, published on December 6 in Science Advances, sheds insight into the complicated world of gene expression and could lead to new therapeutic techniques for diseases caused by improper regulation of gene expression. Gene expression is a fundamental process that occurs within ...

Many recent studies assume that elderly people are at particular risk of dying from extreme heat as the planet warms. A new study of mortality in Mexico turns this assumption on its head: it shows that 75% of heat-related deaths are occurring among people under 35―a large percentage of them ages 18 to 35, or the very group that one might expect to be most resistant to heat. “It’s a surprise. These are physiologically the most robust people in the population,” said study coauthor Jeffrey Shrader of the Center for Environmental Economics and Policy, an affiliate of Columbia University’s Climate School. “I would love to know ...

-With images-   A pioneering international study led by Professor Peter Vickers of Durham University introduces a novel methodology for rapidly assessing scientific consensus on a global scale.   This innovative approach offers the ability to collect real-time, representative data on scientists' opinions across fields, geographical locations, and over time – a breakthrough that could reshape policy-making and public understanding in fields from health sciences to climate change.   The study, conducted in June 2023, brought together a global network ...

“Our results have no clear or direct application right now. It’s basic research that lays the foundation for future technologies in quantum information and quantum computers. There’s enormous potential for completely new discoveries in many different research fields,” says Guilherme B Xavier, researcher in quantum communication at Linköping University, Sweden. But to understand what the researchers have shown, we need to start at the beginning.  That light can be both particles and waves is one of the most illogical – but at the same time fundamental – characteristics ...

The ocean naturally absorbs a quarter to a third of man-made CO2 emissions, but this process also leads to the acidification of seawater. By increasing the alkalinity of seawater through the addition of certain minerals (e.g., carbonates and silicates), the ocean can chemically bind more CO2 without further acidification. However, there is still little research on the environmental effects of Ocean Alkalinity Enhancement (OAE). Scientists from Prof. Ulf Riebesell´s group at GEOMAR Helmholtz Centre for Ocean Research Kiel, as ...

WASHINGTON, D.C. [December 6, 2024] — The National Comprehensive Cancer Network® (NCCN®)—a non-profit alliance of leading cancer centers—hosted a Patient Advocacy Summit in Washington, D.C., today. The annual event brings together leading experts to promote strategies and best practices for improving cancer care. This year’s summit focused on practice and policy solutions for sharing accurate, evidence-based health information with patients and caregivers. It featured a keynote address from W. Kimryn Rathmell, MD, PhD, MMHC, Director of the National Cancer Institute (NCI), along with panel discussions that included Robin Vanderpool, DrPH, Chief of the ...