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Deep learning for phase recovery

Deep learning for phase recovery
2024-01-03
Light, as an electromagnetic field, has two essential components: amplitude and phase. However, optical detectors, usually relying on photon-to-electron conversion (such as charge-coupled device sensors and the human eye), cannot capture the phase of the light field because of their limited sampling frequency. Fortunately, as the light field propagates, the phase delay also causes changes in the amplitude distribution; therefore, we can record the amplitude of the propagated light field and then calculate the corresponding phase, called phase recovery. Some common phase ...

Chicken whisperers: humans crack the clucking code

2024-01-03
A University of Queensland-led study has found humans can tell if chickens are excited or displeased, just by the sound of their clucks.   Professor Joerg Henning from UQ’s School of Veterinary Science said researchers investigated whether humans could correctly identify the context of calls or clucking sounds made by domestic chickens, the most commonly farmed species in the world. “In this study, we used recordings of chickens vocalising in all different scenarios from a previous experiment,” ...

Newly discovered genetic mutation protects against Parkinson’s disease and offers hope for new therapies

2024-01-03
A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson’s disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis School of Gerontology study. The variant, located in a mitochondrial microprotein dubbed SHLP2, was found to be highly protective against Parkinson’s disease; individuals with this mutation are half as likely to develop the disease as those who do not carry it. The variant form of the protein is relatively rare and is found primarily in people of European descent. The findings appear on January 3, 2024, in the journal Molecular Psychiatry. First ...

First dive survey of Lake Tahoe’s lakebed finds high amounts of plastic and other litter

2024-01-03
Plastic litter is a growing problem around the world, and new research shows that the bottom of Lake Tahoe is no exception. In one of the first studies to utilize scuba divers to collect litter from a lakebed, 673 plastic items were counted from just a small fraction of the lake.   In the study, published in the November issue of the journal Applied Spectroscopy, researchers from DRI and the UC Davis Tahoe Environmental Research Center teamed up with the nonprofit Clean Up the Lake to take a close look at the litter. First, ...

Study on extremely preterm infants provides important healthcare knowledge

2024-01-03
Infants born extremely prematurely need to get enrichment as an addition to breast milk. But does it make any difference whether the enrichment is made from breast milk or cow’s milk when it comes to the risk of severe complications in children? This has been investigated by a large clinical study led from Linköping, Sweden. Infants born extremely prematurely, between weeks 22 and 27 of pregnancy, are among the most vulnerable patients in healthcare. The risk of serious complications is very high. Almost one in four extremely premature babies die before the age of one. There is strong research support for giving breast ...

New research shows “Juvenile T. rex” fossils are a distinct species of small tyrannosaur

New research shows “Juvenile T. rex” fossils are a distinct species of small tyrannosaur
2024-01-03
A new analysis of fossils believed to be juveniles of T. rex now shows they were adults of a small tyrannosaur, with narrower jaws, longer legs, and bigger arms than T. rex. The species, Nanotyrannus lancensis, was first named decades ago but later reinterpreted as a young T. rex. The first skull of Nanotyrannus was found in Montana in 1942, but for decades, paleontologists have gone back and forth on whether it was a separate species, or simply a juvenile of the much larger T. rex. Dr Nick Longrich, from the Milner Centre for Evolution at the University ...

Using electricity, scientists find promising new method of boosting chemical reactions

2024-01-02
As the world moves away from gas towards electricity as a greener power source, the to-do list goes beyond cars. The vast global manufacturing network that makes everything from our batteries to our fertilizers needs to flip the switch, too. A study from UChicago chemists found a way to use electricity to boost a type of chemical reaction often used in synthesizing new candidates for pharmaceutical drugs. Published Jan. 2 in Nature Catalysis, the research is an advance in the field of electrochemistry and shows a path forward to designing ...

Combine mindfulness with exercise for mental health boost in 2024 – study

2024-01-02
For people looking to start 2024 with a new routine to feel fitter and happier, a new study from the University of Bath suggests that combining mindfulness with exercise could be your key to success. A study, published in the academic journal Mental Health and Physical Activity, suggests that life changes which combine both physical activity and mindfulness are most effective at lifting mood and improving health and wellbeing. Both physical activity and mindfulness practice have well established psychological benefits. However, ...

New AI tool brings precision pathology for cancer and beyond into quicker, sharper focus

2024-01-02
A new artificial intelligence tool that interprets medical images with unprecedented clarity does so in a way that could allow time-strapped clinicians to dedicate their attention to critical aspects of disease diagnosis and image interpretation. The tool, called iStar (Inferring Super-Resolution Tissue Architecture), was developed by researchers at the Perelman School of Medicine at the University of Pennsylvania, who believe they can help clinicians diagnose and better treat cancers that might otherwise go undetected. The imaging technique provides both highly detailed views of individual cells and a broader look of the ...

Age-related alterations in the oscillatory dynamics serving verbal working memory processing

Age-related alterations in the oscillatory dynamics serving verbal working memory processing
2024-01-02
“[...] we discuss the implications of these novel findings on our understanding of how healthy aging affects verbal working memory processing.” BUFFALO, NY- January 2, 2024 – A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 24, entitled, “Age-related alterations in the oscillatory dynamics serving verbal working memory processing.” Working memory (WM) is a foundational cognitive function involving the temporary storage of information. Unfortunately, WM ...

Is oxygen the cosmic key to alien technology?

Is oxygen the cosmic key to alien technology?
2024-01-02
In the quest to understand the potential for life beyond Earth, researchers are widening their search to encompass not only biological markers, but also technological ones. While astrobiologists have long recognized the importance of oxygen for life as we know it, oxygen could also be a key to unlocking advanced technology on a planetary scale. In a new study published in Nature Astronomy, Adam Frank, the Helen F. and Fred H. Gowen Professor of Physics and Astronomy at the University ...

How tomato plants use their roots to ration water during drought

How tomato plants use their roots to ration water during drought
2024-01-02
Plants have to be flexible to survive environmental changes, and the adaptive methods they deploy must often be as changeable as the shifts in climate and condition to which they adapt. To cope with drought, plant roots produce a water-repellent polymer called suberin that blocks water from flowing up towards the leaves, where it would quickly evaporate. Without suberin, the resulting water loss would be like leaving the tap running. In some plants, suberin is produced by endodermal cells that line the vessels inside the roots. But in others, like tomatoes, suberin is produced in exodermal cells that sit just below ...

Targeted household cleaning can reduce toxic chemicals post-wildfire, Portland State research shows

2024-01-02
After the last embers of a campfire dim, the musky smell of smoke remains. Whiffs of that distinct smokey smell may serve as a pleasant reminder of the evening prior, but in the wake of a wildfire, that smell comes with ongoing health risks. Wildfire smoke is certainly more pervasive than a small campfire, and the remnants can linger for days, weeks and months inside homes and businesses. New research from Portland State’s Elliott Gall, associate professor in Mechanical and Materials Engineering, examined how long harmful chemicals found in wildfire smoke can persist and the ...

New method illuminates druggable sites on proteins

New method illuminates druggable sites on proteins
2024-01-02
LA JOLLA, CA—Identifying new ways to target proteins involved in human diseases is a priority for many researchers around the world. However, discovering how to alter the function of these proteins can be difficult, especially in live cells. Now, scientists from Scripps Research have developed a new method to examine how proteins interact with drug-like small molecules in human cells—revealing critical information about how to potentially target them therapeutically. The strategy, published in Nature Chemical Biology on January 2, 2024, uses a combination of chemistry and analytical techniques to reveal the specific places where proteins and small molecules bind ...

RSV vaccines would greatly reduce illness if implemented like flu shots

2024-01-02
Respiratory syncytial virus (RSV) vaccines recently approved for people 60 and older would dramatically reduce the disease’s significant burden of illness and death in the United States if they were widely adopted like annual influenza vaccines, a new study has found. A high level of RSV vaccination would not only potentially reduce millions of dollars in annual outpatient and hospitalization costs but would also produce an economy of scale with individual shots being delivered at a relatively modest cost of between $117 and $245 per dose, the study said. The vaccines are currently covered by most private insurers without ...

Ga-68 FAPI PET improves detection and staging of pancreatic cancer

Ga-68 FAPI PET improves detection and staging of pancreatic cancer
2024-01-02
Reston, VA—PET imaging with 68Ga-FAPI can more effectively detect and stage pancreatic cancer as compared with 18F-FDG imaging or contrast-enhanced CT, according to new research published in the December issue of The Journal of Nuclear Medicine. In a head-to-head study, 68Ga-FAPI detected more pancreatic tumors on a per-lesion, per-patient, or per-region basis and led to major and minor changes to clinical management of patients. In addition to enhancing precise detection of pancreatic cancer, 68Ga-FAPI ...

Understanding climate mobilities: New study examines perspectives from South Florida practitioners

Understanding climate mobilities: New study examines perspectives from South Florida practitioners
2024-01-02
Understanding Climate Mobilities: New study examines perspectives from South Florida practitioners As climate change continues to impact people across South Florida, the need for adaptive responses becomes increasingly important. A recent study led by researchers at the University of Miami Rosenstiel School of Marine, Atmospheric, and Earth Science, assessed the perspectives of 76 diverse South Florida climate adaptation professionals. The study titled, “Practitioner perspectives on climate mobilities in South Florida” was published in the December issue of the Journal Oxford Open Climate Change, and explores the expectations and concerns of practitioners from the ...

Study: From NYC to DC and beyond, cities on the East Coast are sinking

Study: From NYC to DC and beyond, cities on the East Coast are sinking
2024-01-02
Major cities on the U.S. Atlantic coast are sinking, in some cases as much as 5 millimeters per year – a decline at the ocean’s edge that well outpaces global sea level rise, confirms new research from Virginia Tech and the U.S. Geological Survey. Particularly hard hit population centers such as New York City and Long Island, Baltimore, and Virginia Beach and Norfolk are seeing areas of rapid “subsidence,” or sinking land, alongside more slowly sinking or relatively stable ground, increasing the risk to roadways, runways, building foundations, rail ...

New PET tracer noninvasively identifies cancer gene mutation, allows for more precise diagnosis and therapy

New PET tracer noninvasively identifies cancer gene mutation, allows for more precise diagnosis and therapy
2024-01-02
Reston, VA—A novel PET imaging tracer has been proven to safely and effectively detect a common cancer gene mutation that is an important molecular marker for tumor-targeted therapy. By identifying this mutation early, physicians can tailor treatment plans for patients to achieve the best results. This research was published in the December issue of The Journal of Nuclear Medicine. Kirsten rat sarcoma (KRAS) is a commonly mutated oncogene that is present in approximately 20-70 percent of cancer cases. Patients with KRAS mutations usually respond poorly to standard therapies. As such, the National Comprehensive ...

Evolution might stop humans from solving climate change, says new study

Evolution might stop humans from solving climate change, says new study
2024-01-02
Central features of human evolution may stop our species from resolving global environmental problems like climate change, says a new study led by the University of Maine. Humans have come to dominate the planet with tools and systems to exploit natural resources that were refined over thousands of years through the process of cultural adaptation to the environment. University of Maine evolutionary biologist Tim Waring wanted to know how this process of cultural adaptation to the environment might influence the goal of solving global environmental problems. ...

January issues of APA journals cover antidepressant outcomes, disparities in school-based support, civil commitment hearings, and more

2024-01-02
WASHINGTON, D.C., Jan 2, 2024 — The latest issues of three American Psychiatric Association journals, The American Journal of Psychiatry, Psychiatric Services and The American Journal of Psychotherapy are now available online.   The January issue of The American Journal of Psychiatry features studies focusing on improving clinical outcomes and informing new interventions. Highlights include: Predicting Acute Changes in Suicidal Ideation and Planning: A Longitudinal Study of Symptom Mediators and the Role of the Menstrual ...

Memory, brain function, and behavior: exploring the intricate connection through fear memories

Memory, brain function, and behavior: exploring the intricate connection through fear memories
2024-01-02
In a world grappling with the complexities of mental health conditions like anxiety, depression, and PTSD, new research from Boston University neuroscientist Dr. Steve Ramirez and collaborators offers a unique perspective. The study, recently published in the Journal of Neuroscience, delves into the intricate relationship between fear memories, brain function, and behavioral responses. Dr. Ramirez, along with his co-authors Kaitlyn Dorst, Ryan Senne, Anh Diep, Antje de Boer, Rebecca Suthard, Heloise ...

Demystifying a key receptor in substance use and neuropsychiatric disorders

Demystifying a key receptor in substance use and neuropsychiatric disorders
2024-01-02
New York, NY (January 2, 2024)—Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication asenapine, a possible therapeutic target for substance use and neuropsychiatric disorders. This discovery may pave the way for the development of improved medications targeting the same pathway. Their findings, detailed in the January 2 online issue of Nature Communications https://doi.org/10.1038/s41467-023-44601-4, show that a brain protein known as the TAAR1 receptor, a drug target known to regulate dopamine signaling in key reward pathways in the brain, differs ...

Elusive cytonemes guide neural development, provide signaling ‘express route’

Elusive cytonemes guide neural development, provide signaling ‘express route’
2024-01-02
St. Jude Children’s Research Hospital scientists found that cytonemes (thin, long, hair-like projections on cells) are important during neural development. Cytonemes connect cells communicating across vast distances but are difficult to capture with microscopy in developing vertebrate tissues. The researchers are the first to find a way to visualize how cytonemes transport signaling molecules during mammalian nervous system development. The findings were published in Cell.  “We showed cytonemes are a direct express route for signal transport,” said corresponding author ...

Pioneering study indicates a potential treatment for corneal endothelial disease, reducing the need for corneal transplants

Pioneering study indicates a potential treatment for corneal endothelial disease, reducing the need for corneal transplants
2024-01-02
Philadelphia, January 2, 2024 – Findings from a pioneering study in The American Journal of Pathology, published by Elsevier, reveal that administration of the neuropeptide α-melanocyte–stimulating hormone (α-MSH) promotes corneal healing and restores normal eye function to an otherwise degenerating and diseased cornea by providing protection against cell death and promoting cell regeneration. Due to a lack of currently available medical therapy, patients suffering from corneal endothelial disease, ...
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