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Texas A&M team develops polymers that can kill bacteria

2023-12-22
Antibiotic-resistant bacteria have become a rapidly growing threat to public health. Each year, they account for more than 2.8 million infections, according to the U.S. Centers for Disease Control and Prevention. Without new antibiotics, even common injuries and infections harbor the potential to become lethal. Scientists are now one step closer to eliminating that threat, thanks to a Texas A&M University-led collaboration that has developed a new family of polymers capable of killing bacteria without inducing antibiotic resistance by disrupting the membrane of these microorganisms. “The new polymers we synthesized could help fight antibiotic ...

How jellyfish regenerate functional tentacles in days

How jellyfish regenerate functional tentacles in days
2023-12-22
At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days — but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage. Jellyfish, along with other cnidarians such as corals and sea anemones, exhibit high regeneration abilities, but how they form the critical blastema has remained a mystery until now. A research team based in Japan has revealed that stem-like proliferative cells — which are actively growing and dividing but ...

Reindeer sleep while chewing their cud

Reindeer sleep while chewing their cud
2023-12-22
Researchers report December 22 in the journal Current Biology that the more time reindeer spend ruminating, the less time they spend in non-rapid eye movement (non-REM) sleep. EEG recordings revealed that reindeer’s brainwaves during rumination resemble the brain waves present during non-REM sleep, and these brainwave patterns suggest that the reindeer are more “rested” after ruminating. The researchers speculate that this multitasking might help reindeer get enough sleep during the summer months, when food is abundant ...

Trends in abdominoplasty: More outpatient surgery and concomitant liposuction

2023-12-22
Waltham — December 22, 2023 —   Abdominoplasty continues to be a safe and effective procedure, with more cases performed on an outpatient basis and increased use of concomitant liposuction, according to a new 16-year analysis in the January issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.   "Taking advantage of quality-improvement data submitted by US Board-certified plastic surgeons, our study provides new insight ...

Like kids in a candy store 

Like kids in a candy store 
2023-12-22
Kyoto, Japan – A non-prescription drug abuse crisis in Japan seems only one overdose away. The demand for a particular anti-cough drug has been rising, along with the social impact of its abuse due to its psychosomatic effects.  The ease of obtaining information online about how to acquire over-the-counter medications or OTCs for achieving overdose, however, does not appear to be the real problem. Now, a study by a team of researchers at Kyoto University suggests that reliable information about OTC abuse needs to be readily available and effectively disseminated.  "We ...

Robots versus humans: Which would children trust more when learning new information?

Robots versus humans: Which would children trust more when learning new information?
2023-12-22
In this digital age, children are exposed to overwhelming amounts of information online, some of it unverified and increasingly generated by non-human sources, such as AI-driven language models. As children grow older, the ability to assess a source’s reliability is an important skill in cultivating critical thinking. Children aged three to five years display selective trust based on the informant’s past accuracy when faced with both humans and robots, according to a study published in the journal Child Development titled, ‘Younger, not older, ...

AI tool aids in screening for nerve disorder

AI tool aids in screening for nerve disorder
2023-12-22
Researchers at the Indian Institute of Science (IISc), in collaboration with Aster-CMI Hospital, have developed an AI tool that can identify the median nerve in ultrasound videos and detect carpal tunnel syndrome (CTS). The study was published in IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.   CTS arises when the median nerve, which runs from the forearm into the hand, is compressed at the carpal tunnel part of the wrist, resulting in numbness, tingling or pain. It ...

Big impacts from small changes in cell

Big impacts from small changes in cell
2023-12-22
  Tiny things matter – for instance, one amino acid can completely alter the architecture of the cell. Researchers at the Universities of Göttingen and Warwick investigated the structure and mechanics of the main component of the cytoskeleton of the cell: a protein known as actin. Actin is found in all living cells where it has a range of important functions – from muscle contraction to cell signalling and cell shape. This protein comes in two different varieties termed “isoforms”, which are known as gamma actin and beta actin. The difference between the two proteins is ...

Jupiter was targeted by exoplanet hunter

Jupiter was targeted by exoplanet hunter
2023-12-22
For the first time, an instrument to find planets light years away was used on an object in the Solar System, in a study on Jupiter's winds. We find ourselves at a time when it has become almost commonplace to discover planets orbiting another star, with more than 5,000 already registered. The first distant worlds to incorporate this list were mainly giant planets, similar to but also very different in many ways from Jupiter and Saturn. Astrophysicists have already begun to obtain data on the atmospheres of exoplanets, but fundamental ...

Pandemic lessons: Insights into how mobility restrictions affect healthcare costs

Pandemic lessons: Insights into how mobility restrictions affect healthcare costs
2023-12-22
Osaka, Japan - As the world grappled with lockdowns and restrictions brought by the COVID-19 pandemic, researchers at Osaka Metropolitan University conducted an extensive study to elucidate the link between changes in human mobility and the impact on medical costs associated with lifestyle-related diseases. Dr. Haruka Kato and Professor Atsushi Takizawa of the Graduate School of Human Life and Ecology at Osaka Metropolitan University were concerned by the negative health effects resulting from the restriction of ...

Controlling thermoelectric conversion in magnetic materials by magnetization direction

Controlling thermoelectric conversion in magnetic materials by magnetization direction
2023-12-22
1. NIMS has succeeded in directly observing the "anisotropic magneto-Thomson effect," a phenomenon in which the heat absorption/release proportional to an applied temperature difference and charge current (i.e., Thomson effect) changes anisotropically depending on the magnetization direction in magnetic materials. This research is expected to lead to further development of basic physics and materials science related to the fusion area of thermoelectrics and spintronics, as well as to development of new functionalities to control thermal energy with magnetism. 2. The Thomson effect has long been known as one of the fundamental ...

Stinky, bitter, and painful: A novel insect repellent attacks multiple sensory pathways

Stinky, bitter, and painful: A novel insect repellent attacks multiple sensory pathways
2023-12-22
Okazaki, Japan – crop damage in agriculture and the transmission of vector-borne diseases by insect pests have become worldwide threat nowadays. Chemical treatments such as insecticides and repellents have been a major strategy against insect pests for centuries. Due to limited understanding of mechanisms of insect avoidance behavior, however, development of insect repellents has been delayed. To discover compounds that effectively repel insect pests, it is important to focus on key molecules associated with sensory, particularly aversive, responses. In this study, researchers ...

Microglia act as a “facilitator and stabilizer” for anesthesia

Microglia act as a “facilitator and stabilizer” for anesthesia
2023-12-22
Though it may be a surprise to the millions of people who undergo general anesthesia every year for medical procedures, the biological mechanism for how different anesthetics block consciousness is still not fully understood. However, researchers may be one step closer after uncovering the way small immune cells in the brain called microglia are impacted by general anesthesia. The research was presented in a paper published in eLife on 22/Dec/2023. “We found that microglia play an important role in regulating the body’s response to general anesthesia. ...

3D-printed flat-bone-mimetic bioceramic scaffolds for cranial restoration

3D-printed flat-bone-mimetic bioceramic scaffolds for cranial restoration
2023-12-22
The cranial bone in the human body performs very important functions, such as protecting the brain and enabling the passage of the cranial nerves that are essential to physiological functioning. Critical-sized cranial defects can disrupt both the physical and psychological well-being of patients. Restoration of critical-sized cranial defects by cranioplasty is challenging for reconstructive surgeons, who prefer to use autologous bone grafts. The acquisition of autologous bone requires additional surgeries concomitant with risks such as free flap loss, infection, deep venous thrombosis, and nerve injury. These limitations necessitate the development ...

TTUHSC's Reddy elected fellow by the National Academy of Inventors

TTUHSCs Reddy elected fellow by the National Academy of Inventors
2023-12-22
P. Hemachandra Reddy, Ph.D., a professor in the Texas Tech University Health Sciences Center (TTUHSC) School of Medicine’s Department of Internal Medicine who has researched healthy aging, dementia and other neurodegenerative diseases for more than 20 years, recently was named to the 2023 class of Fellows for the National Academy of Inventors (NAI). The NAI is a member organization comprised of U.S. and international universities and governmental and nonprofit research institutes with more than 4,600 individual inventor members and fellows spanning more than 300 institutions worldwide. ...

Light colour is less important for the internal clock than originally thought

2023-12-22
Vision is a complex process. The visual perception of the environment is created by a combination of different wavelengths of light, which are decoded as colours and brightness in the brain. Photoreceptors in the retina first convert the light into electrical impulses: with sufficient light, the cones enable sharp, detailed, and coloured vision. Rods only contribute to vision in low light conditions allowing for different shades of grey to be distinguished but leaving vision much less precise. The electrical nerve impulses are finally transmitted to ganglion cells in the retina and then via the optic nerve to the visual cortex in the ...

Scientists develop ‘flying dragon’ robot to fight fires from a distance

Scientists develop ‘flying dragon’ robot to fight fires from a distance
2023-12-22
Imagine a flying dragon that doesn’t spout fire, but instead extinguishes it with blasts of water. Thanks to a team of Japanese researchers, this new kind of beast may soon be recruited to firefighter teams around the world, to help put out fires that are too dangerous for their human teammates to approach. The blueprint of this novel firefighter robot, called the Dragon Firefighter, has now been published in Frontiers in Robotics and AI. And as it has been published as Open Science, roboticists around the world may freely ...

Sunday sales reign supreme and other takeaways from review of farmers market transactions

2023-12-21
CORNELL UNIVERSITY MEDIA RELATIONS OFFICE FOR RELEASE: Dec. 21, 2023 Kaitlyn Serrao 607-882-1140 kms465@cornell.edu     ITHACA, N.Y. – Cornell researchers partnered with New York livestock farmers to analyze transactions at farmers markets, finding that sales were better on Sundays, early in the morning, and during certain months of the year. The study, which researchers believe is the first peer-reviewed analysis of customer-level transaction data at farmers markets, gives new insights into how farmers can make markets more profitable for them. The researchers and farmers used point-of-sale devices that record sales ...

Palliative care is underused for patients with malignant urinary obstruction

2023-12-21
Less than half of patients with malignant ureteral obstruction (MUO) – a serious complication of advanced cancer, with a poor prognosis – receive palliative care (PC) for their condition, reports a paper in the January issue of Urology Practice®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.  Hospice care can promote patient comfort while avoiding aggressive and invasive treatments for MUO patients nearing the end ...

JCEHP supplement aims to disrupt assumptions about continuing professional development

2023-12-21
December 7, 2023 —The Journal of Continuing Education in the Health Professions (JCEHP) has published a supplement, "Conceptual Advances in Continuing Professional Development in the Health Professions," in which scholars of continuing professional development (CPD) creatively examine prevailing assumptions and propose new theoretical frameworks and empirical insights. Publication of the supplemental issue is supported by the Society for Academic Continuing Medical Education (SACME). JCEHP, the official journal of the Alliance for Continuing Education in the Health Professions, ...

Researchers awarded $3 million to develop AI to better detect aggressive prostate cancer

2023-12-21
Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have received a five-year, $3 million grant from the National Cancer Institute to identify novel cancer biomarkers and develop AI that can detect and predict aggressive prostate cancer to help avoid unnecessary treatments and their associated negative side effects. Despite recent advancements, prostate cancer remains a common and serious health issue for men, and current methods of screening and risk assessment can often lead to overdiagnosis and overtreatment. About 90% of people diagnosed with prostate cancer receive treatment, even though ...

GPCR structure: Research reveals molecular origins of function for a key drug target

GPCR structure: Research reveals molecular origins of function for a key drug target
2023-12-21
Through an international collaboration, scientists at St. Jude Children’s Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand. They discovered precisely which amino acids control the key pharmacological properties of the ligand. The adrenaline receptor studied is a member of the G protein-coupled receptor (GPCR) family, and this family is the target of one-third of all Food and Drug Administration (FDA)-approved drugs. Thus, understanding how ...

Structures of Parkinson’s disease-linked proteins offer a framework for understanding how they work together

Structures of Parkinson’s disease-linked proteins offer a framework for understanding how they work together
2023-12-21
Scientists at St. Jude Children’s Research Hospital revealed the complex structure of two Parkinson’s disease-related proteins, both of which are implicated in late-onset cases. Leucine-rich repeat kinase 2 (LRRK2) is a protein kinase that modifies other proteins in a process called phosphorylation; Rab29, a member of the Rab GTPase family that regulates cellular trafficking, modulates the activity of LRRK2. How Rab29 and LRRK2 work synergistically to cause Parkinson’s disease remains ...

Male breast cancer diagnosis fuels groundbreaking treatment tool

Male breast cancer diagnosis fuels groundbreaking treatment tool
2023-12-21
Doctors diagnosed Christopher Gregg, Ph.D., member of the Nuclear Control of Cell Growth and Differentiation Program at Huntsman Cancer Institute at the University of Utah (the U) and neuroscientist and professor of neurobiology and human genetics at the U, with stage 4 metastatic breast cancer in 2018. At that point, he started thinking of ways to improve his treatment. “The core problem of metastatic cancer is it evolves,” says Gregg. “There may be a treatment that works today but eventually ...

NASA’s Hubble watches ‘spoke season’ on Saturn

NASA’s Hubble watches ‘spoke season’ on Saturn
2023-12-21
This photo of Saturn was taken by NASA's Hubble Space Telescope on October 22, 2023, when the ringed planet was approximately 850 million miles from Earth. Hubble's ultra-sharp vision reveals a phenomenon called ring spokes. Saturn's spokes are transient features that rotate along with the rings. Their ghostly appearance only persists for two or three rotations around Saturn. During active periods, freshly-formed spokes continuously add to the pattern. In 1981, NASA's Voyager 2 first photographed the ring spokes. NASA's Cassini orbiter also saw the spokes during its 13-year-long mission that ended in 2017. Hubble continues ...
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