HSS research shows obesity is associated with worse flare symptoms and quality of life in people with early rheumatoid arthritis
2023-11-12
SAN DIEGO, CA, NOVEMBER 12, 2023 — A recent study from Hospital for Special Surgery (HSS) and others has found a correlation between obesity and more severe disease flare symptoms that negatively affect quality of life in patients with early rheumatoid arthritis (RA), a systemic, autoimmune, inflammatory disorder affecting multiple joints in the body. The study will be presented at ACR Convergence 2023, the annual meeting of the American College of Rheumatology.
RA is usually treated with a combination of medications to relieve swelling and pain while regulating the immune ...
Long-term blood pressure control after hypertensive pregnancy following physician-optimized self-management
2023-11-11
About The Study: Self-monitoring and physician-guided titration of antihypertensive medications was associated with lower blood pressure during the first nine months postpartum than usual postnatal outpatient care in this randomized clinical trial involving 220 participants in the United Kingdom.
Authors: Paul Leeson, Ph.D., of the University of Oxford in Oxford, United Kingdom, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2023.21523)
Editor’s ...
Cut salt, cut blood pressure
2023-11-11
· High blood pressure is the leading cause of morbidity and mortality
· Losing one teaspoon of salt a day results in systolic blood pressure decline comparable to effect achieved with drugs
· First study to show people already on blood pressure medication could further lower their blood pressure by reducing sodium
Chicago --- Nearly everyone can lower their blood pressure, even people currently on blood pressure-reducing drugs, by lowering their sodium intake, reports a new study from Northwestern Medicine, Vanderbilt University Medical Center and the University of Alabama at Birmingham.
“In the study, ...
Effect of dietary sodium on blood pressure
2023-11-11
About The Study: Dietary sodium reduction significantly lowered blood pressure in the majority of middle-aged to elderly adults in this study including 213 participants. The decline in blood pressure from a high- to low-sodium diet was independent of hypertension status and antihypertensive medication use, was generally consistent across subgroups, and did not result in excess adverse events.
Authors: Deepak K. Gupta, M.D., M.S.C.I., of the Vanderbilt University Medical Center in Nashville, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2023.23651)
Editor’s ...
Aspirin and hemocompatibility events with a left ventricular assist device in advanced heart failure
2023-11-11
About The Study: This randomized clinical trial found that in patients with advanced heart failure treated with a fully magnetically levitated left ventricular assist device, avoidance of aspirin as part of an antithrombotic regimen, which includes a vitamin K antagonist, is not inferior to a regimen containing aspirin, does not increase thromboembolism risk, and is associated with a reduction in bleeding events.
Authors: Mandeep R. Mehra, M.D., M.Sc., of Brigham and Women’s Hospital and Harvard Medical School in Boston, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link ...
New AHA Center for Telehealth™ will increase access to quality health care and improve delivery
2023-11-11
According to the American Medical Association, approximately 25% of all patients used telehealth services during the last year, exceeding the 5% who accessed their care this way before the pandemic.[1] The American Heart Association (AHA) Center for Telehealth, unveiled today, recognizes the critical role telehealth can play as a solution to close gaps in health care access, particularly in rural and underserved areas, and deliver quality care to populations that have little to no access to traditional ...
New study finds coronary calcium scores highly effective in identifying heart disease in people without any known risk factors
2023-11-11
While high cholesterol, high blood pressure, diabetes and smoking are well known heart disease risks, not everyone who has a heart attack has them. In fact, previous research has shown that 14% to 27% of heart attack patients have none of these risk factors.
Now, a new study from researchers at Intermountain Health in Salt Lake City finds that these patients had one thing in common: they all tended to have high levels of coronary calcium.
Results of the new Intermountain study show that scans that detect this kind of plaque buildup should be considered as ...
Understanding the stressed, depressed, adolescent brain
2023-11-11
WASHINGTON — Advanced brain imaging techniques reveal how adolescent brain development influences, and is influenced by, factors including chronic stress and mood disorders. The findings will be presented on Monday, November 13, 11:15 a.m. – 12:15 p.m. EST at Neuroscience 2023, the annual meeting of the Society for Neuroscience and the world’s largest source of emerging news about brain science and health.
Adolescence is a time of social, biological, and emotional changes, as well as continued brain development. Mental health among teenagers was already declining before the COVID-19 pandemic, according to data from the Centers for Disease Control ...
The brain’s response to a changing environment
2023-11-11
WASHINGTON — Changes in a person’s environment can have long-term, significant effects on the brain, whether it’s the inhalation of wildfire smoke or the experience of childhood trauma. The findings will be presented on Tuesday, November 14, 11:15 a.m. – 12:15 p.m. at Neuroscience 2023, the annual meeting of the Society for Neuroscience and the world’s largest source of emerging news about brain science and health.
The environment plays an important role in a person’s brain health and cognitive function. Previous research has established that both one’s physical and social environment effect the brain and nervous system. Next, researchers ...
The AI edge: How new tools are advancing neuroscience
2023-11-11
WASHINGTON — Using machine learning, researchers are able to use data from the brain to glean deeper insights and apply this new knowledge in clinical settings. The findings will be presented on Monday, November 13, 2–3 p.m. EST at Neuroscience 2023, the annual meeting of the Society for Neuroscience and the world’s largest source of emerging news about brain science and health.
Machine learning is a branch of artificial intelligence (AI) that centers on enabling computers to analyze data in increasingly complex ...
Advances in predicting Alzheimer’s disease
2023-11-11
WASHINGTON — Researchers are making strides toward understanding and detecting Alzheimer’s disease in its earliest stages, when interventions may be most effective at slowing the progress of the disease. The findings will be presented on Sunday, November 12, 11:30 a.m. – 12:30 p.m. EST at Neuroscience 2023, the annual meeting of the Society for Neuroscience and the world’s largest source of emerging news about brain science and health.
Alzheimer’s disease (AD) is a neurodegenerative ...
The biological blueprint for depression and its cognitive effects
2023-11-11
WASHINGTON — In studies that examine the depressed brain, researchers were able to identify specific genes, molecules, brain regions, and cognitive features that are associated with the disorder. The findings will be presented on Monday, November 13, 10–11 a.m. EST at Neuroscience 2023, the annual meeting of the Society for Neuroscience and the world’s largest source of emerging news about brain science and health.
More than 8% of adults in the United States suffer from severe depression, and the percentage is higher ...
Unraveling anxiety: The roles of virtual reality, companionship, and infantile amnesia
2023-11-11
WASHINGTON — Innovative experimental approaches with human participants and animal models point to the effects of fear and stress on the brain — and suggest ways to ameliorate these impacts. The findings will be presented on Monday, November 13, 12:45–1:45 p.m. at Neuroscience 2023, the annual meeting of the Society for Neuroscience and the world’s largest source of emerging news about brain science and health.
Fear and anxiety are normal, healthy emotional responses to some stimuli; however, there ...
Exploring psychedelics: Understanding variability in treatment responses
2023-11-11
WASHINGTON — Psychedelic compounds such as psilocybin, a substance found in various mushroom species, are garnering more research support as novel treatments for psychiatric disorders, but questions remain concerning who they may help the most. The findings will be presented on Tuesday, November 14, 1–2 p.m. at Neuroscience 2023, the annual meeting of the Society for Neuroscience and the world’s largest source of emerging news about brain science and health.
Psychiatric disorders, including phobias, post-traumatic stress disorder (PTSD), depression, and substance use disorder, represent a major public health issue. Current behavioral and pharmacological ...
Scientific strength through diverse datasets
2023-11-11
Research which considers the diversity of normal and diseased human populations is contributing to more resilient hypotheses regarding complex neuroscience processes, such as human brain development, autism spectrum disorders, and Alzheimer's disease. Several interwoven examples will be discussed on Sunday, November 12, 2–3 p.m. at Neuroscience 2023, the annual meeting of the Society for Neuroscience and the world’s largest source of emerging news about brain science and health.
Considering the full spectrum of human variability — including gender, sex, race, ethnicity, and neurodiversity — is benefiting neuroscience at both the basic and translational ...
The sleep debt epidemic: Memory problems and sex-specific effects
2023-11-11
WASHINGTON — Researchers have a better understanding of sleep disruption — particularly in the realm of sex-specific differences and cellular dysfunction — and are developing new research to study the interplay between sleep and memory. The findings will be presented on Tuesday, November 14, 10–11 a.m. EST at Neuroscience 2023, the annual meeting of the Society for Neuroscience and the world’s largest source of emerging news about brain science and health.
Approximately one out of every three adults in the United States report not getting enough sleep. Despite years of research into sleep and memory, neuroscientists still do not ...
Different transfusion approaches for helping heart attack patients who develop anemia recover led to similar 30-day outcomes
2023-11-11
For immediate release on Nov. 11, 2023 at 10:10 a.m. E.T.
A National Institutes of Health-supported study found that the type of transfusion approach used to support adults who developed anemia after a heart attack did not make a significant difference in their likelihood of having another heart attack or dying within 30 days. Participants in the trial were randomized to receive a red blood cell transfusion when their red blood cell counts were in a prespecified range of moderate anemia, which is considered a liberal approach, or when it was more severe, ...
Transfusing more blood may benefit patients who have had heart attack and have anemia
2023-11-11
An international clinical trial led by physician Jeffrey L. Carson, distinguished professor of medicine at Rutgers Robert Wood Johnson Medical School, found that a liberal blood transfusion given to patients who have had a heart attack and have anemia may reduce the risk of a reoccurrence and improve survival rates. The results of the trial, Myocardium Infarction and Transfusion (MINT), were published today in the New England Journal of Medicine. Maria Mori Brooks, professor of epidemiology and biostatistics at the University of Pittsburgh School of Public Health, co-first authored the study.
“Transfusion threshold trials are important to help physicians inform decisions that provide ...
Natural language processing for adjudication of heart failure in a multicenter clinical trial
2023-11-11
About The Study: This secondary analysis of a randomized clinical trial validated a natural language processing model developed within a single healthcare system to identify heart failure hospitalizations. Further study is needed to determine whether natural language processing will improve the efficiency of future multicenter clinical trials by identifying clinical events at scale.
Authors: Scott D. Solomon, M.D., of Brigham and Women’s Hospital in Boston, is the corresponding author.
To access the embargoed study: ...
International clinical trial finds that semaglutide reduced cardiovascular events by 20% in adults with overweight or obesity who don’t have diabetes
2023-11-11
Cleveland: Findings from a multi-center, international clinical trial reported by a Cleveland Clinic physician show that semaglutide reduced cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease who do not have diabetes.
Semaglutide is primarily prescribed for adults with type 2 diabetes but is also approved for chronic weight management in adults with obesity or overweight and have at least one other health issue. In the trial, patients treated with semaglutide lost an average of 9.4% of their body weight and experienced improvements in other risk factors for cardiovascular disease.
Results ...
Key clues to DNA repair mechanism might lead to new cancer treatments
2023-11-11
Tokyo, Japan – Researchers from Tokyo Metropolitan University have identified key factors in the mechanism behind DNA repair in our bodies. For the first time, they showed that the “proofreading” portion of the DNA replicating enzyme polymerase epsilon ensured safe termination of replication at damaged portions of the DNA strand, ultimately saving DNA from severe damage. This new knowledge arms scientists with ways to make anti-cancer drugs more effective, and new diagnostic methods.
Our DNA is under attack. Every day, around 55,000 single-strand breaks (SSBs) appear in the strands making up DNA helices ...
Do pets make you happier? MSU study shows they didn’t during the pandemic
2023-11-10
MSU has a satellite uplink/LTN TV studio and Comrex line for radio interviews upon request.
There is a general understanding that pets have a positive impact on one’s well-being. A new study by Michigan State University found that although pet owners reported pets improving their lives, there was not a reliable association between pet ownership and well-being during the COVID-19 pandemic.
The study, published in the Personality and Social Psychology Bulletin, assessed 767 people over three times in May 2020. The researchers took a mixed-method ...
Want higher graduation rates? New study shows public spending on families is key
2023-11-10
MSU has a satellite uplink/LTN TV studio and Comrex line for radio interviews upon request.
A new study, conducted in collaboration between researchers at Michigan State University and Central Michigan University, found that public spending on social safety net programs and on education spending each independently impact high school graduation rates, which are a key predictor of health and well-being later in life.
The study, published in the Journal of Adolescent Health, tested whether public financing for education and social safety net programs that aim to help ...
MSU researcher solves sperm mystery, providing insight on infertility
2023-11-10
MSU has a satellite uplink/LTN TV studio and Comrex line for radio interviews upon request.
Video and Images
Michigan State University researchers have solved the mystery of a poorly understood sperm structure called the cytoplasmic droplet, or CD. The CD is an expanded cytoplasm — watery, gel-like cell contents enclosed by cell membrane — found close to the head, at the neck of the sperm, in all mammals, including humans. This new genetic model is the first of its kind.
Despite ...
Are consumers ready for robots to show up at their doorstep?
2023-11-10
With Amazon aiming to make 10,000 deliveries with drones in Europe this year and Walmart planning to expand its drone delivery services to an additional 60,000 homes this year in the states, companies are investing more research and development funding into drone delivery, But are consumers ready to accept this change as the new normal?
Northwestern University’s Mobility and Behavior Lab, led by Amanda Stathopoulos, an associate professor of civil and environmental engineering, wanted to know if consumers were ready for robots to replace delivery drivers, in the form ...
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