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Endometrial cancer: New insights into a deadly disparity

2023-12-20
The numbers are stark and deeply troubling. Endometrial cancer — which develops in the lining of the uterus (womb) and is sometimes called uterine cancer — is on the rise in the U.S. In 1987, there were 35,000 cases annually. That number has nearly doubled in 2023 to more than 66,000 cases. Deaths from the disease have also grown alarmingly in the same period, from less than 3,000 to more than 13,000 in the U.S. every year. And the trend line is not getting better. “Endometrial cancer has been increasing at unprecedented levels over the past five years,” ...

Sanford Burnham Prebys continues unprecedented recruitment of early-career scientists

Sanford Burnham Prebys continues unprecedented recruitment of early-career scientists
2023-12-20
Continuing its rapid and dramatic recruitment of emerging, top-tier researchers, Sanford Burnham Prebys has hired two more highly regarded early-career scientists: Angela Liou, M.D., a specialist in pediatric oncology and hematology; and Xueqin Sherine Sun, Ph.D., a cancer biologist and genome engineer.   “With Drs. Liou and Sun, we have now hired eight superb young scientists and physicians in less than a year, an achievement that reflects the extraordinary challenges in biomedical research today and our ambitious plans ...

Research offers a reason why diversity in plant species causes higher farming yield, solving 'a bit of a mystery'

Research offers a reason why diversity in plant species causes higher farming yield, solving a bit of a mystery
2023-12-20
LAWRENCE — A study appearing in Nature Communications based on field and greenhouse experiments at the University of Kansas shows how a boost in agricultural yield comes from planting diverse crops rather than just one plant species: Soil pathogens harmful to plants have a harder time thriving. “It’s commonly observed that diverse plant communities can be more productive and stable over time,” said corresponding author James Bever, senior scientist with the Kansas Biological Survey & Center for Ecological Research and Foundation Distinguished Professor of Ecology & Evolutionary Biology at KU. ...

UM School of Medicine review highlights rise in psychiatric disorders linked to increased cannabis use

UM School of Medicine review highlights rise in psychiatric disorders linked to increased cannabis use
2023-12-20
The widespread use of cannabis (marijuana) and its increased potency are associated with a rise in cannabis-related psychiatric conditions, according to a new University of Maryland School of Medicine (UMSOM) review article that was recently published in the New England Journal of Medicine. It highlights the urgent need for doctors to screen for and treat patients who are experiencing symptoms of cannabis use disorder, which means they are experiencing significant problems from their use of the drug.   Nearly one in five Americans ages 12 and older used cannabis in 2021, according to the article, and more than 16 million met the criteria for ...

Immune system plays crucial step in creating blood stem cells

Immune system plays crucial step in creating blood stem cells
2023-12-20
AMES, Iowa – A microbial sensor that helps identify and fight bacterial infections also plays a key role in the development of blood stem cells, valuable new insight in the effort to create patient-derived blood stem cells that could eliminate the need for bone marrow transplants.  The discovery by a research team led by Raquel Espin Palazon, an assistant professor of genetics, development and cell biology at Iowa State University, was published last month in Nature Communications. It builds on prior ...

New grant gives South Carolina life sciences companies a chance to accelerate

New grant gives South Carolina life sciences companies a chance to accelerate
2023-12-19
The Medical University of South Carolina is one of nine leading research universities across six states partnering with Innosphere Ventures on its Regional Life Sciences Incubator. Innosphere Ventures is a Colorado-based life sciences incubator with proven methods for propelling startups to successful market entry. Funding from a $2 million three-year Build to Scale Venture Challenge grant from the U.S. Department of Commerce will create a regional incubator that will offer its partnering institutions and selected startups ...

Predicting prenatal care to improve pregnancy outcomes

2023-12-19
Socioeconomic factors, like education and location, can affect access to life-saving prenatal care services. Researchers at Boston Children’s Hospital are taking steps towards implementing strategies that improve access to prenatal care: estimating how many pregnant people attend the recommended number of visits and identifying pregnant people who are at high risk of failing to attend. This could help policymakers allocate resources to populations not getting enough prenatal care and could, in turn, improve health outcomes for mothers and babies. Led by Grace Chan, M.D., Ph.D., Attending Physician in the Intermediate Care Program at Boston ...

JMIR Medical Education accepted for MEDLINE indexing

2023-12-19
JMIR Publications is pleased to announce that JMIR Medical Education has passed the Scientific Quality Review for MEDLINE and has been accepted for inclusion in MEDLINE, which is the U.S. National Library of Medicine's premier bibliographic database. JMIR Medical Education was already indexed in PubMed. MEDLINE is a more selective subset of PubMed, consisting of the top 5,200 biomedical journals, and indexing in MEDLINE also means that articles are now also indexed with NLM Medical Subject Headings (MeSH terms) and other metadata. Selection for MEDLINE is a result of a thorough review ...

Fish display distinct individual behaviours when swimming to find food

Fish display distinct individual behaviours when swimming to find food
2023-12-19
Fish from the same species can evolve their sense of smell and display individual foraging ‘personalities’ to successfully find food in different habitats, according to new research.   In the study, published today as a Reviewed Preprint in eLife, researchers developed a high-throughput behavioural assay to test spontaneous swimming and differences in the sense of smell of individual Mexican cavefish larvae. eLife editors described the work as important, presenting compelling evidence that the surface and cave morphs of the fish show different olfactory preferences and odour sensitivities, and that individual fish show substantial variability in their spontaneous ...

Protein allows poison dart frogs to accumulate toxins safely

Protein allows poison dart frogs to accumulate toxins safely
2023-12-19
Scientists have identified the protein that helps poison dart frogs safely accumulate their namesake toxins, according to a study published today in eLife. The findings solve a long-standing scientific mystery and may suggest potential therapeutic strategies for treating humans poisoned with similar molecules. Alkaloid compounds, such as caffeine, make coffee, tea and chocolate delicious and pleasant to consume, but can be harmful in large amounts. In humans, the liver can safely metabolise modest ...

Toxic chemicals found in oil spills and wildfire smoke detected in killer whales

2023-12-19
Toxic chemicals produced from oil emissions and wildfire smoke have been found in muscle and liver samples from Southern Resident killer whales and Bigg’s killer whales. A study published today in Scientific Reports is the first to find polycyclic aromatic hydrocarbons (PAHs) in orcas off the coast of B.C., as well as in utero transfer of the chemicals from mother to fetus. “Killer whales are iconic in the Pacific Northwest—important culturally, economically, ecologically and more. Because they are able to metabolically process PAHs, these are most likely recent exposures. Orcas are our canary in the coal ...

Schar school researchers to receive funding for nonprofit employment data project

2023-12-19
Schar School Researchers To Receive Funding For Nonprofit Employment Data Project  Alan Abramson, Professor, Government and Politics; Mirae Kim, Associate Professor, Nonprofit Studies; and Stefan Toepler, Professor, Nonprofit Studies, are set to receive funding for: "Nonprofit Employment Data Project."  The researchers will produce a comprehensive report on nonprofit employment in the United States, based on new data that is expected to be released by the U.S. Bureau of Labor Statistics (BLS) early in 2024. The researchers will also arrange for the transfer of the Nonprofit Works interactive database application, which is currently hosted by Johns ...

Nanoparticles with antibacterial action shorten duration of tuberculosis treatment

Nanoparticles with antibacterial action shorten duration of tuberculosis treatment
2023-12-19
A low-cost technology involving nanoparticles loaded with antibiotics and other antimicrobial compounds that can be used in multiple attacks on infections by the bacterium responsible for most cases of tuberculosis has been developed by researchers at São Paulo State University (UNESP) in Brazil and is reported in an article published in the journal Carbohydrate Polymers. Results of in vitro tests suggest it could be the basis for a treatment strategy to combat multidrug bacterial resistance. According ...

Marzougui & Kan developing crashworthy tangent end treatment for low-speed & curbed roadways

2023-12-19
Marzougui & Kan Developing Crashworthy Tangent End Treatment For Low-Speed & Curbed Roadways   Dhafer Marzougui, Associate Professor, Physics and Astronomy, and Cing-Dao Kan, Professor/Director, Center for Collision Safety and Analysis,  received $749,954 from the National Cooperative Highway Research Program for: "Development of a Crashworthy Tangent End Treatment for Low-Speed and Curbed Roadways."  This funding began in Nov. 2023 and will end in Nov. 2026.  ### About George Mason University George Mason University is Virginia's largest public research university. ...

A malaria drug treatment could save babies’ lives

2023-12-19
Wars, drought, displacement, and instability are causing a dramatic increase in the number of pregnant and breastfeeding women around the world who suffer from malnutrition. Without access to sufficient nutrients in the womb, babies born to these women are more likely to die due to complications like pre-term birth, low birth weight, and susceptibility to diseases like malaria. To try to reduce the risk of malarial infection, the WHO recommends that pregnant women in low-income countries be treated with a combination of the antimalarial drugs sulfadoxine and pyrimethamine ...

Engineered human heart tissue shows Stanford Medicine researchers the mechanics of tachycardia

2023-12-19
Heart rates are easier to monitor today than ever before. Thanks to smartwatches that can sense a pulse, all it takes is a quick flip of the wrist to check your heart. But monitoring the cells responsible for heart rate is much more challenging — and it’s encouraged researchers to invent new ways to analyze them. Joseph Wu, M.D., Ph.D., director of the Stanford Cardiovascular Institute and professor of medicine and of radiology, has devised a new stem cell-derived model of heart tissue ...

Molecular jackhammers’ ‘good vibrations’ eradicate cancer cells

Molecular jackhammers’ ‘good vibrations’ eradicate cancer cells
2023-12-19
The Beach Boys’ iconic hit single “Good Vibrations” takes on a whole new layer of meaning thanks to a recent discovery by Rice University scientists and collaborators, who have uncovered a way to destroy cancer cells by using the ability of some molecules to vibrate strongly when stimulated by light. The researchers found that the atoms of a small dye molecule used for medical imaging can vibrate in unison ⎯ forming what is known as a plasmon ⎯ when stimulated by near-infrared light, causing the cell membrane of cancerous cells to rupture. ...

Nearly 30% of caregivers for severe stroke survivors experience psychological distress

2023-12-19
Stroke is an abrupt, devastating disease that instantly changes a person’s life and has the potentially to cause lasting disability or death. However, the condition also has profound effects on the patient’s loved ones — who are often called to make difficult decisions quickly. A new study led by Michigan Medicine finds that nearly 30% of caregivers of severe stroke patients experience high levels of anxiety, depression or post-traumatic stress during the first year after the patient leaves the hospital. The results are published in Neurology. “As physicians, we usually concentrate on our ...

MSU research suggests pandas are active posters on ‘social media’

2023-12-19
MSU has a satellite uplink/LTN TV studio and Comrex line for radio interviews upon request. Images   Pandas, long portrayed as solitary creatures, do hang with family and friends — and they’re big users of “social media.” Scent-marking trees serve as a panda version of Facebook. An article in the international journal Ursus paints a new lifestyle picture of the beloved bears in China’s Wolong National Nature Reserve, a life that’s shielded from human eyes because they’re shy, rare and live in densely forested, remote areas. No one really knows how pandas hang, but a new study indicates pandas are around others more than previously thought. ...

UTHSC, Vanderbilt University receive $2.4 million grant to promote diversity in speech-language pathologists for high-need children

UTHSC, Vanderbilt University receive $2.4 million grant to promote diversity in speech-language pathologists for high-need children
2023-12-19
The Department of Audiology and Speech Pathology at the University of Tennessee Health Science Center and the Department of Hearing and Speech Sciences at Vanderbilt University have secured a $2,399,454 grant to fund a five-year project to address the need for diversity in highly trained professionals in speech-language pathology. The project, known as Project PAL (Preparing Academic Leaders in Speech-Language Pathology to Teach, Conduct Research, and Engage in Professional Service to Improve Outcomes for Children with High Need Communication Disorders), ...

American University receives $5.7 million from NSF to bridge research and policy, address real-world challenges

2023-12-19
American University won a $5.7 million cooperative research agreement from the U.S. National Science Foundation’s Accelerating Research Translation program. The award will help AU foster greater use of evidence in the public and private sectors by producing new knowledge on best practices in research translation, training scholars in the effective conduct of research translation, and supporting the dissemination of research findings that have the potential to benefit society. The ART program ...

UTRF Innovation Awards celebrate UTHSC researchers

UTRF Innovation Awards celebrate UTHSC researchers
2023-12-19
The University of Tennessee Research Foundation (UTRF) celebrated the researchers whose achievements are making life better locally, nationally, and globally at its annual Innovation Awards ceremony, held December 14 at the Mooney Library at the University of Tennessee Health Science Center (UTHSC) in Memphis. The Innovation Awards recognize researchers from all over the UT System who partner with UTRF to bring their innovations to market. “Turning research into practical, sustainable solutions calls for resilience, adaptability, and market savvy. Let's collectively celebrate the foundational research successes that made ...

Groundbreaking hip-focused physical therapy reduces low back pain

Groundbreaking hip-focused physical therapy reduces low back pain
2023-12-19
When the University of Delaware’s Gregory Hicks started his research career two decades ago, he was one of only a few people in the United States studying chronic low back pain in people over 60 years old. Fast-forward to today, the research on back pain has ramped up, yet studies of older adults with the problem are still sparse. “Unfortunately, the societal attitude is that older people don’t warrant the same level of care that younger people do when it comes to musculoskeletal problems,” said Hicks, Distinguished Professor of Health Sciences at UD. “But I don’t believe that for a ...

Researchers report detailed analysis of heart injury caused by yellow fever virus

Researchers report detailed analysis of heart injury caused by yellow fever virus
2023-12-19
To fill gaps in knowledge of yellow fever (YF), a group of researchers in Brazil affiliated with the Department of Pathology at the University of São Paulo’s Medical School (FM-USP), Hospital das Clínicas (HC, the hospital complex run by FM-USP), the Heart Institute (InCor, linked to HC) and Emílio Ribas Institute of Infectious Diseases (IIER) decided to study the pathogenesis of YF-associated heart injury. The team was led by Fernando Rabioglio Giugni, a cardiologist, and Amaro Nunes Duarte-Neto, an infectious disease specialist and pathologist; both work at FM-USP.  “There’s still no specific treatment for yellow fever. Patients receive ...

David Kaplan named fellow of the National Academy of Inventors

David Kaplan named fellow of the National Academy of Inventors
2023-12-19
David Kaplan, the Stern Family Endowed Professor of Engineering, has been named a fellow of the National Academy of Inventors (NAI). Election as an academy fellow is the highest professional distinction awarded solely to inventors. The NAI was founded to recognize and encourage inventors with U.S. patents and enhance the visibility of academic technology and innovation. As a member of the Class of 2023, Kaplan will be honored at the NAI’s annual meeting on June 18, 2024 in Raleigh, North ...
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