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Alexander Zholents recognized with 2023 Dieter Möhl Award

2023-12-18
Zholents was honored for his work on the theory of optical stochastic cooling. Alexander Zholents, a senior physicist at the U.S. Department of Energy’s (DOE) Argonne National Laboratory and distinguished fellow in the Accelerator Systems division is one of the recipients of this year’s Dieter Möhl Award. The award is presented by CERN, the European laboratory for particle physics. It is in tribute to the late Dieter Möhl, a pioneer in the realm of particle beam cooling. The awards celebrate both early career and lifetime achievements in the field of beam cooling and its applications. “I am deeply honored to receive this award,” said Zholents. ​“The ...

Unraveling predisposition in bilateral Wilms tumor

Unraveling predisposition in bilateral Wilms tumor
2023-12-18
(Memphis, Tenn.—December 18, 2023) Children with bilateral Wilms tumor have a tumor in each of their kidneys — a condition that strongly suggests an underlying genetic or epigenetic predisposition driving the disease. Scientists at St. Jude Children’s Research Hospital gathered a large cohort of bilateral Wilms tumor samples and conducted analyses to assess which factors contribute to predisposition comprehensively. The work has implications for counseling patient families, guiding treatment decisions and informing the design of future clinical trials. The study was published today in Nature Communications.   Having tumors in ...

Feelings of impatience evolve over time, study says

2023-12-18
A new study answers a timely question: What is the hardest part of waiting? Consumers do plenty of it—online, in line, in traffic, or for deliveries. And now we know it’s the final phase that’s most problematic for them.  In this season of joyful—and not-so-joyful—anticipation, the research has deep implications for marketers and psychological insights for us all, says Annabelle Roberts, coauthor and assistant professor of marketing at the University of Texas McCombs School of Business. The paper shows: It’s better for companies to communicate possible delays early in the wait;  It’s better for ...

Little bacterium may make big impact on rare-earth processing

2023-12-18
ITHACA, N.Y. - A tiny, hard-working bacterium – which weighs one-trillionth of a gram – may soon have a large influence on processing rare earth elements in an eco-friendly way. In a new study, Cornell University scientists show that genetically engineering this bacterium could improve the efficiency for the purification of elements found in smartphones, computers, electric cars and wind turbines, and could even boost global economic supply chains. Vibrio natriegens, the bacterium, offers a sustainable ...

AI generates proteins with exceptional binding strengths

AI generates proteins with exceptional binding strengths
2023-12-18
A new study Dec. 18 in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring. Scientists at the Institute for Protein Design at the University of Washington School of Medicine used software to create protein molecules that bind with exceptionally high affinity and specificity to a variety of challenging biomarkers, including human hormones. Notably, the scientists achieved the highest interaction strength ever reported between a computer-generated biomolecule and its target. Senior author David Baker, professor of biochemistry at UW Medicine, ...

Artificial intelligence can predict events in people's lives

Artificial intelligence can predict events in peoples lives
2023-12-18
Artificial intelligence developed to model written language can be utilized to predict events in people's lives. A research project from DTU, University of Copenhagen, ITU, and Northeastern University in the US shows that if you use large amounts of data about people's lives and train so-called 'transformer models', which (like ChatGPT) are used to process language, they can systematically organize the data and predict what will happen in a person's life and even estimate the time of death. In a new scientific article, 'Using Sequences of Life-events to Predict Human Lives', published ...

Einstein receives $10.9 million grant to validate remote cognitive testing for Alzheimer’s and other dementias

Einstein receives $10.9 million grant to validate remote cognitive testing for Alzheimer’s and other dementias
2023-12-18
December 18, 2023—(BRONX NY)—Neurologists often diagnose Alzheimer’s disease after evaluating patients during lengthy, in-person office visits. This poses a significant challenge for many groups, particularly people with limited access to specialized care, including people from historically marginalized groups and people living in rural areas. Albert Einstein College of Medicine has received a five-year, $10.9 million grant from the National Institutes of Health (NIH) to study whether remote neuropsychological testing can substitute for in-person office visits when assessing whether people have Alzheimer’s disease or other dementias. “In-person ...

The antibiotic resistance war (video)

The antibiotic resistance war (video)
2023-12-18
WASHINGTON, Dec. 18, 2023 — There’s a microscopic battle happening right before our eyes, involving the critical issue of antibiotic resistance. Witness the historical development of antibiotics, from penicillin's accidental discovery to the ongoing battle against superbugs. https://www.youtube.com/watch?v=OCR5wFWSGlA Reactions is a video series produced by the American Chemical Society and PBS Digital Studios. Subscribe to Reactions at http://bit.ly/ACSReactions and follow us on Twitter @ACSReactions. The American Chemical Society (ACS) is ...

AI's memory-forming mechanism found to be strikingly similar to that of the brain

AIs memory-forming mechanism found to be strikingly similar to that of the brain
2023-12-18
An interdisciplinary team consisting of researchers from the Center for Cognition and Sociality and the Data Science Group within the Institute for Basic Science (IBS) revealed a striking similarity between the memory processing of artificial intelligence (AI) models and the hippocampus of the human brain. This new finding provides a novel perspective on memory consolidation, which is a process that transforms short-term memories into long-term ones, in AI systems. In the race towards developing ...

15th annual horizon scan identifies 15 most pressing issues for conservation, including invertebrate decline and changing marine ecosystems

15th annual horizon scan identifies 15 most pressing issues for conservation, including invertebrate decline and changing marine ecosystems
2023-12-18
Since 2009, the Cambridge Conservation Initiative has coordinated an annual horizon scan, a well-established method for predicting which threats, changes, and technologies will have the biggest impact on biological conservation in the following year. This year, the 15th horizon scan included 31 scientists, practitioners, and policymakers who developed a list of 96 issues, which they eventually narrowed down to the fifteen most novel and impactful. Their findings, publishing in the journal Trends in Evolution & Ecology ...

Toothbrushing tied to lower rates of pneumonia among hospitalized patients

2023-12-18
Toothbrushing also associated with lower rates of ICU mortality, shorter duration of mechanical ventilation, and shorter ICU length of stay  Researchers say toothbrushing could be a cheap but effective way to help lower rates of hospital-acquired pneumonia  Researchers have found an inexpensive tool that may help reduce rates of pneumonia for hospitalized patients—and it comes with bristles on one end. A new study by investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, and Harvard Pilgrim Health Care Institute ...

Ecosystem benefits to humanity expected to decline by 9% by 2100

Ecosystem benefits to humanity expected to decline by 9% by 2100
2023-12-18
As climate change redistributes terrestrial ecosystems across the globe, the world’s natural capital is expected to decrease, causing a 9% loss of ecosystem services by 2100. That’s according to a study of natural capital published today in the journal Nature led by scientists at the University of California, Davis, and Scripps Institution of Oceanography at UC San Diego. Breathable air, clean water, healthy forests and biodiversity all contribute to people’s well-being in ways that ...

Public benefit programs and differential associations with child maltreatment by race and ethnicity

2023-12-18
About The Study: The results of this study raise concerns that benefit programs may add relative advantages for white children compared with Black and Hispanic children and contribute to racial and ethnic disparities in child protective services investigations. States’ eligibility criteria and distribution practices should be examined to promote equitable effects on adverse child outcomes.  Authors: Henry T. Puls, M.D., of Children’s Mercy Kansas City, is the corresponding author. To access the embargoed study: Visit our For The Media website ...

Association between daily toothbrushing and hospital-acquired pneumonia

2023-12-18
About The Study: The findings of this systematic review and meta-analysis of 15 randomized clinical trials with an effective population size of 2,786 patients suggest that daily tooth brushing may be associated with significantly lower rates of hospital-acquired pneumonia, particularly in patients receiving mechanical ventilation, lower rates of intensive care unit (ICU) mortality, shorter duration of mechanical ventilation, and shorter ICU length of stay. Policies and programs encouraging more widespread and consistent toothbrushing ...

Secret vulnerabilities of cancer’s ‘death star’ revealed

Secret vulnerabilities of cancer’s ‘death star’ revealed
2023-12-18
Researchers at the Centre for Genomic Regulation in Barcelona, Spain, and the Wellcome Sanger Institute near Cambridge, UK, have comprehensively identified the allosteric control sites found in the protein KRAS. These are highly sought after targets for drug development, representing secret vulnerabilities which can be exploited to control the effects of one of the most important causes of cancer. The study presents the first complete control map for any protein and is published today (18 December) in the journal Nature.  KRAS ...

Toronto study identifies new concepts for GLP-1 action in the brain, the 2023 Science magazine breakthrough of the year

Toronto study identifies new concepts for GLP-1 action in the brain, the 2023 Science magazine breakthrough of the year
2023-12-18
Research pioneer Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named 2023 breakthrough of the year by the Science Magazine. Not only have millions of people with type 2 diabetes benefitted from GLP-1 agonists, but the drugs also produced wide-ranging health benefits beyond weight loss in two recent patient trials. For years, GLP-1 agonists have been known to have a fortuitous side effect of improving metabolic health, but how this is regulated in the body remains unclear. Now Dr. ...

Coral atoll islands may outpace sea-level rise with local ecological restoration, scientists say

2023-12-18
Ecological restoration may save coral atoll islands from the rising seas of climate change, according to an international team of scientists, conservationists, and an indigenous leader.   While global carbon emission reduction is imperative, local measures could be the key to the islands outpacing sea levels, they argue today in the journal Trends in Ecology & Evolution.   “Far from being doomed, in their natural state most coral atoll islands could adapt to sea level rise”, says Dr Sebastian Steibl from the University of Auckland ...

NIH researchers create genetic atlas detailing early stages of zebrafish development

NIH researchers create genetic atlas detailing early stages of zebrafish development
2023-12-18
Researchers at the National Institutes of Health have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types. These diverse cells become tissues and organs that form juvenile fish capable of swimming and looking for food. The findings are published in Developmental Cell. “Perhaps surprisingly, tiny zebrafish provide us with significant insight ...

Unleashing canine travel: Hospitality and tourism sector urged to adapt to dog-friendly travel demands

2023-12-18
Estimated to be worth USD 50.1 billion by 2030, a Surrey team of researchers has uncovered the potential of the growing dog-friendly travel market. The Covid-19 pandemic drove an increase in UK household dog ownership, creating a need for tourism providers to adapt to accommodate these four-legged family members.  The Surrey team set out to understand why people travel with their dogs, how they feel about it, and what challenges they face doing so.  Lori Hoy, PhD Researcher and lead author of the study at the University of Surrey, said:  "Some reports suggest that the UK dog population stands at 11 million, with 29% of UK adults having a dog in their ...

More parallel ‘traffic' observed in human brains than in animals

More parallel ‘traffic observed in human brains than in animals
2023-12-18
In a study comparing human brain communication networks with those of macaques and mice, EPFL researchers found that only the human brains transmitted information via multiple parallel pathways, yielding new insights into mammalian evolution. When describing brain communication networks, EPFL senior postdoctoral researcher Alessandra Griffa likes to use travel metaphors. Brain signals are sent from a source to a target, establishing a polysynaptic pathway that intersects multiple brain regions “like a road with many stops along the way.” She explains that structural brain ...

The role of oxidized tryptophan residues in repairing damaged photosystem II protein

The role of oxidized tryptophan residues in repairing damaged photosystem II protein
2023-12-18
Photosynthesis refers to the fundamental biological process of the conversion of light energy into chemical energy by chlorophyll (a green pigment) containing plants. This seemingly routine process in plants sustains all the biological life and activities on Earth. First reaction of photosynthesis occurs at a site called photosystem II (PSII), present on the thylakoid membrane in the chloroplast where light energy is transferred to chlorophyll molecules. PSII is made up of a complex group of proteins, including the D1 and D2 reaction center proteins. Light ...

Breaking the mold: Zarbio and Georgia State scientists unveil game-changing theory on Alzheimer's disease

Breaking the mold: Zarbio and Georgia State scientists unveil game-changing theory on Alzheimers disease
2023-12-18
Despite affecting millions worldwide, Alzheimer's disease (AD) has long lacked effective treatments due to a fundamental inadequacy of our understanding of its etiology and pathogenesis. The absence of an integrative theory connecting the molecular origins of AD with disturbances at the organelle and cell levels, changes in relevant biomarkers, and population-level prevalence has hindered progress. Even though most scientists only hope that an integrative theory of AD will emerge soon, scientists from Zarbio and Georgia State University discovered sufficient data to formulate a framework for such a theory. The molecular and cellular ...

Scientists collect aardvark poop to understand how the species is impacted by climate in Africa

Scientists collect aardvark poop to understand how the species is impacted by climate in Africa
2023-12-18
CORVALLIS, Ore. – In a first-of-its-kind study of aardvarks, Oregon State University researchers spent months in sub-Saharan Africa collecting poop from the animal and concluded that aridification of the landscape is isolating them, which they say could have implications for their long-term survival. “Everyone had heard of aardvarks and they are considered very ecologically important but there has been little study of them,” said Clint Epps, a wildlife biologist at Oregon State. “We wanted to see if we could collect enough data to begin to understand them.” In ...

Thalassemia screening in Thailand: Medical Sciences Dean advocates for elevated trust

Thalassemia screening in Thailand: Medical Sciences Dean advocates for elevated trust
2023-12-18
- Insights from Professor Sakorn Pornprasert, Dean, Faculty of Associated Medical Sciences at Chiang Mai University, on raising thalassemia awareness in Thailand. Thalassemia, a genetic disorder affecting hemoglobin production, poses a significant public health challenge in Thailand, with a high prevalence and substantial healthcare costs. According to Thailand's Ministry of Public Health, approximately 18-24 million or 30-40 percent of the Thai population carries the thalassemia gene. Professor Sakorn Pornprasert, Dean, Faculty of Associated Medical Sciences, Chiang Mai University, shared his views on BGI Genomics Global 2023 State of Thalassemia Awareness ...

Lung nodule program provides benefits patients ineligible for lung cancer screening

Lung nodule program provides benefits patients ineligible for lung cancer screening
2023-12-18
(Denver—December 18, 2023) – Adopting a lung nodule program (LNP) may increase the detection of early lung cancer for patients who are not eligible for lung cancer screening under existing age eligibility criteria, according to a study published in the Journal of Thoracic Oncology, an official journal of the International Association for the Study of Lung Cancer. LNPs are established to follow up on lung nodules that are frequently identified during routine imaging for reasons other than suspected lung cancer or lung cancer screening. The research was conducted by a team led by Dr. Raymond U. Osarogiagbon, MBBS, FACP, chief scientist ...
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