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Gut bacteria of malnourished children benefit from key elements in therapeutic food

2023-12-14
A clinical trial reported in 2021 and conducted by a team of researchers from Washington University School of Medicine in St. Louis and the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh, showed that a newly designed therapeutic food aimed at repairing malnourished children’s underdeveloped gut microbiomes was superior to a widely used standard therapeutic food. Now, another study from the same research team at Washington University School of Medicine has identified key, naturally occurring biochemical components of this new therapeutic food and the important bacterial strains that process these ...

Gayle Benson makes historic donation for new home for Ochsner Children’s Hospital

Gayle Benson makes historic donation for new home for Ochsner Children’s Hospital
2023-12-14
NEW ORLEANS, La. – Ochsner Health announces plans for The Gayle and Tom Benson Ochsner Children’s Hospital, made possible through a transformational gift from Mrs. Gayle Benson.   “We are proud to unveil much-anticipated plans for a new home for Louisiana’s No. 1 ranked children’s hospital,” said Pete November, CEO, Ochsner Health. “Ochsner is deeply grateful for Mrs. Benson and her unparalleled act of generosity, which will significantly impact the lives of countless families throughout Louisiana and the Gulf South. This facility will enable us to care for more children, retain and attract top pediatric physicians ...

Enzymes can’t tell artificial DNA from the real thing

Enzymes can’t tell artificial DNA from the real thing
2023-12-14
The genetic alphabet contains just four letters, referring to the four nucleotides, the biochemical building blocks that comprise all DNA. Scientists have long wondered whether it’s possible to add more letters to this alphabet by creating brand-new nucleotides in the lab, but the utility of this innovation depends on whether or not cells can actually recognize and use artificial nucleotides to make proteins. Now, researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego have ...

Decline in smoking in England has stalled since pandemic

2023-12-14
A decades-long decline in smoking prevalence in England has nearly ground to a halt since the start of the pandemic, according to a new study led by UCL researchers. The study, funded by Cancer Research UK and published in the journal BMC Medicine, looked at survey responses from 101,960 adults between June 2017 and August 2022. Before the Covid-19 pandemic, from June 2017 to February 2020, smoking prevalence fell by 5.2% a year, but this rate of decline slowed to 0.3% during the pandemic (from April 2020 to August 2022), the study ...

3G microbial cell factories: achieving sustainable goals with engineered microorganisms

3G microbial cell factories: achieving sustainable goals with engineered microorganisms
2023-12-14
Fossil fuels are at the heart of most human activities, contributing to the increase in greenhouse gas emissions and the ever-rising atmospheric carbon dioxide (CO2) levels. CO2 levels are projected to increase exponentially in future, resulting in severe environmental and ecological impacts. A beacon of hope amidst this chaos are eco-friendly alternatives to fossil fuels. Green energy sources can be developed using advanced biotechnological techniques. One such intervention is the use of biorefineries or microbial cell factories, that convert biomass (organic matter like plants and solid waste) into energy and valuable by-products. The first (1G) ...

Using deep learning to identify teens most in need of mental health support

Using deep learning to identify teens most in need of mental health support
2023-12-14
The personal yet global struggle with mental health may be more visible now than ever before. Yet many people still find it difficult to access the support they need. In Japan, suicide is sadly the leading cause of death for young people. Researchers, including from the University of Tokyo, have carried out a six-year study to better understand the myriad of factors which can impact adolescent mental health. After surveying 2,344 adolescents and their caregivers, and using computer-based deep learning to process the results, they were able to identify five categories which the young people could be grouped into. Nearly 40% of those involved were ...

The Lancet Psychiatry: Mental health care and research must directly confront systemic racism to improve the health and lives of Black Americans

2023-12-14
Improving the mental health and wellness of Black Americans requires acknowledging and confronting systemic racism underlying the US political, social, and healthcare systems that create and maintain racial inequality in every aspect of life for Black people in the USA.  The new Series of three papers on Black mental health in the USA, plus an essay from Black Americans with lived experience, published inThe Lancet Psychiatry journal, outlines the overwhelming evidence for the role racism plays in producing, maintaining, and amplifying mental health disparities for Black Americans. Against this background, the authors call for a comprehensive analysis of the conditions and systems in ...

Alarm over lax oversight of weight loss drug ads that could harm patients

2023-12-14
UK organisations responsible for protecting the public from prescription-only drug adverts are putting patients at risk from the harms of weight loss drugs by not enforcing the law, reveals an investigation published by The BMJ today. Legal responsibility for regulating adverts for medicines in the UK rests with the Medicines and Healthcare products Regulatory Agency (MHRA) on behalf of health ministers. But there is also a system of self-regulation with a number of bodies operating their own codes of practice, including the Advertising Standards Authority (ASA). But The BMJ has found that the MHRA has not issued a single sanction for prescription drugs in the last ...

Post-meal insulin surge not a villain, says new research

2023-12-14
Researchers at Sinai Health have unearthed vital information about the relationship between insulin levels after eating and long-term heart and metabolic health. The research upends the notion that insulin surge following food intake is a bad thing. On the contrary – it could be an indicator of good health to come. Led by Dr. Ravi Retnakaran, Clinician-Scientist at the Lunenfeld-Tanenbaum Research Institute, part of Sinai Health, the study set out to explore how insulin levels after meals impact cardiometabolic health. While past ...

Body dissatisfaction linked with depression risk in children

2023-12-14
Body dissatisfaction at age 11 is linked to increased risk of depression by age 14, finds a new longitudinal study led by UCL researchers. The findings, published in The Lancet Psychiatry, show that body image concerns explain a large proportion of an association between body mass index (BMI) and depression in children, particularly in girls. The study, supported by Wellcome, involved 13,135 participants of the Millennium Cohort Study, a UCL-led nationally representative birth cohort study of people born between 2000 and 2002. The researchers found that high BMI at age seven was linked with increased depressive symptoms (which can include low mood, loss of pleasure ...

Study explores accuracy of computerized ADHD test

2023-12-14
A new study cautions against using the QbTest as a standalone diagnostic or screening tool for ADHD. Rather, the study authors highlight the intended use of the QbTest as a component of a full clinical assessment, since it could help clinicians reach faster diagnostic decisions and reduce waiting lists. Researchers from the Universities of Southampton, Nottingham, Cardiff, and King’s College London explored the accuracy and clinical utility of a widely used computerised test for Attention-deficit/hyperactivity disorder (ADHD), called the QbTest. They found that, when used on its own, QbTest is not good enough ...

Researcher says men should abstain from drinking at least three months prior to conceiving

2023-12-14
Researchers at Texas A&M University have already shown that paternal drinking habits prior to conception can have a negative effect on fetal development — with semen from men who regularly consume alcohol impacting placenta development, fetal alcohol syndrome (FAS)-associated brain and facial defects, and even IVF outcomes. In an article published this month in Andrology, the lab of Dr. Michael Golding has now demonstrated that it takes much longer than previously believed, longer than a month, for the effects of alcohol consumption to leave the father’s ...

Was the earthquake induced or natural? New study tests frameworks to answer the question

2023-12-14
Using questionnaires created to determine whether a particular earthquake is natural or induced by human activity, a panel of experts concluded that the November 2022 magnitude 5.2 Peace River earthquake sequence in Alberta, Canada was likely to be induced. The case study published in Seismological Research Letters was a serendipitous test of two recent questionnaire-based frameworks established to distinguish natural and induced earthquakes, the latter of which are mostly caused by hydraulic fracturing or injected water disposal wells associated with oil and gas recovery. The Peace River ...

Making probiotics more widely applicable through ‘CRISPR’ engineering

Making probiotics more widely applicable through ‘CRISPR’ engineering
2023-12-14
Humans can benefit significantly from symbiotic relationships with probiotics—live bacteria and microorganisms that influence the gut microbiota. When consumed in appropriate amounts, probiotics can promote gut health, support the immune system, and enhance metabolism. Probiotics, widely regarded as a treasure in the field of microbiology, are currently finding new applications in medicine, animal care, and the food industry. However, it is often challenging to use probiotics in their existing form, owing to varying effects ...

Decoding the ‘chassis effect”: host physiology emerges as key predictor

Decoding the ‘chassis effect”: host physiology emerges as key predictor
2023-12-14
Synthetic biology is a growing discipline of science that involves redesigning naturally occurring organisms to express new, useful attributes.  These engineered organisms can be used to address issues unresolved by conventional methods.   Broad-host-range (BHR) synthetic biology is an emerging domain that aims to expand the pool of model hosts or ‘chassis,’ by utilizing the rich diversity of the naturally evolving microbial world. The chassis provides a platform for the expression of ...

Texas A&M researcher says men should abstain from drinking at least three months prior to conceiving

Texas A&M researcher says men should abstain from drinking at least three months prior to conceiving
2023-12-13
By Courtney Price, Texas A&M University School of Veterinary Medicine & Biomedical Sciences Researchers at Texas A&M University have already shown that paternal drinking habits prior to conception can have a negative effect on fetal development — with semen from men who regularly consume alcohol impacting placenta development, fetal alcohol syndrome (FAS)-associated brain and facial defects, and even IVF outcomes. In an article published this month in Andrology, ...

CUNY SPH partners with UNFPA on campaign to end gender-based violence

2023-12-13
New York, NY | December 13, 2023 – The CUNY Graduate School of Public Health and Health Policy (CUNY SPH) has partnered with the United Nations Population Fund (UNFPA) on the 16 Days of Activism against Gender-Based Violence campaign, an initiative to bring global awareness to the widespread issue of gender-based violence, a pervasive public health threat. The 16 Days campaign was launched in 1991 at the first Women’s Global Leadership Institute held by the Center for Global Women’s Leadership (CGWL), with the goal of raising awareness ...

The A+ team tackles AI and quantum computing hardware

The A+ team tackles AI and quantum computing hardware
2023-12-13
NEWPORT NEWS, VA – Superconducting technologies are the lifeblood of the U.S. Department of Energy’s Thomas Jefferson National Accelerator Facility in its ongoing mission to probe the quarks and gluons inhabiting the quantum universe. Superconducting radiofrequency (SRF) technology, a core competency of Jefferson Lab, is used to accelerate the fundamental electron particles in the lab’s Continuous Electron Beam Accelerator Facility, enabling researchers from around the world to conduct cutting-edge experiments to study the fundamental building blocks of matter. With the investment from DOE’s Office ...

Can telehealth assessments identify infants more likely to be on the autism spectrum?

Can telehealth assessments identify infants more likely to be on the autism spectrum?
2023-12-13
Is it possible to identify infants more likely to be on the autism spectrum through telehealth assessments? The UC Davis MIND Institute’s Meagan Talbott, a professional researcher in the Department of Psychiatry and Behavioral Sciences, has received a $3.2 million grant to seek the answer to that question. The five-year grant is from the National Institute of Child Health and Human Development. Talbott is now recruiting for a national study of 120 infants, 6-12 months of age, who are showing delays or differences in their development. Parents might have questions about autism or other conditions, but ...

Virginia Tech researcher probes the potential for preventing and reversing age-related memory loss

Virginia Tech researcher probes the potential for preventing and reversing age-related memory loss
2023-12-13
About 40 percent of people over age 65 suffer some form of age-related memory loss, which puts them at higher risk for developing dementia and Alzheimer’s disease. However, there are currently no approved methods for preventing memory loss with age. Tim Jarome, associate professor of neurobiology in the Virginia Tech College of Agriculture and Life Sciences’ School of Animal Sciences is hoping to change that, aided by a $433,000 grant from the National Institute on Aging, which is part of the National Institutes of Health. Jarome and his research partner, Assistant Professor Sydney Trask of Purdue University’s Department ...

Mpox (monkeypox) vaccine triggers equally strong immune response in smaller than usual doses and in people with or without HIV

2023-12-13
Delivering the two-dose mpox vaccine, called JYNNEOS, in smaller than the usual FDA-approved doses, and by injection between layers of the skin rather than by the standard route under the skin, produced a detectable immune response, a new study shows. This also occurred regardless of whether people were living with or without HIV. Led by researchers at NYU Grossman School of Medicine, the study showed no significant difference in the strength of the immune response (as gauged by the amount of detectable IgG antibodies, immune proteins that help kill the mpox virus) between most of those who received their vaccine injections in small doses ...

Interactive screen use reduces sleep time in kids, researchers find

2023-12-13
UNIVERSITY PARK, Pa. — While screen time is generally known to affect sleep, new research suggests that interactive engagement, such as texting friends or playing video games, delays and reduces the time spent asleep to a greater extent than passive screen time, like watching television — especially for teens.   The research, which published today (Dec. 13) in the Journal of Adolescent Health, demonstrates that adolescents at age 15 who used screens to communicate with friends or play video games in the hour before bed took 30 minutes longer to fall asleep than if they had refrained from interactive screen time. But it wasn’t just interactive screen time ...

New study shows exercise can boost brain health

2023-12-13
Santa Monica, Calif. (Dec. 12, 2023) – A fascinating link between regular exercise and better brain health has been revealed, according to an international study that included a team of clinical researchers from Pacific Neuroscience Institute’s Brain Health Center, located at Providence Saint John’s Health Center.  The research, detailed in the paper "Exercise-Related Physical Activity Relates to Brain Volumes in 10,125 Individuals," was published this week in the Journal of Alzheimer’s Disease and shows being physically active is related to increased size of brain areas important ...

UNC researchers reveal prevalence of persistent symptoms in patients with microscopic colitis

UNC researchers reveal prevalence of persistent symptoms in patients with microscopic colitis
2023-12-13
It’s a hidden cause of diarrhea and the development of the disease is poorly understood. Multiple factors work against the diagnosis of microscopic colitis, an inflammatory digestive disease, because the symptom distress compared to patients with other causes of chronic diarrhea remains unknown. Now, a new study published in journal Gastro Hep Advances, shows patients may be unsure of a diagnosis based on their colonoscopy results, patients may not be prescribed the proper medications, and many patients may remain symptomatic one year after colonoscopy. The ...

Don't say vegan: Americans more likely to choose vegan food if labeled ‘healthy’ and ‘sustainable’

2023-12-13
There may be a simple way to convince meat eaters to consume vegan food, according to a new USC study: Don’t call the food “vegan.” Americans were far less likely to choose a gourmet gift basket without meat or dairy if it was labeled “vegan” or “plant-based,” according to a nationally representative survey of more than 7,500 U.S. adults. By contrast, labeling the basket “healthy” and/or “sustainable” roughly doubled the likelihood that Americans ...
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