Hebrew prayer book fills gap in Italian earthquake history
2023-11-01
The chance discovery of a note written in a 15th century Hebrew prayer book fills an important gap in the historical Italian earthquake record, offering a brief glimpse of a previously unknown earthquake affecting the Marche region in the central Apennines.
Paolo Galli, who found the note in the Apostolic Vatican Library while looking for contemporaneous accounts of another historic Italian earthquake, writes in Seismological Research Letters that the note “not only helps us partially fill a gap in the seismic history ...
UChicago chemists make breakthrough in drug discovery chemistry
2023-11-01
For years, if you asked the people working to create new pharmaceutical drugs what they wished for, at the top of their lists would be a way to easily replace a carbon atom with a nitrogen atom in a molecule.
But two studies from chemists at the University of Chicago, published in Science and Nature, offer two new methods to address this wish. The findings could make it easier to develop new drugs.
“This is the grand-challenge problem that I started my lab to try to solve,” said Mark Levin, ...
Docetaxel use associated with significant reduction in prostate cancer death in very poor prognostic group
2023-11-01
Men with high-grade prostate cancer and low prostate-specific antigen (PSA) levels have a poor prognosis. The question remains as to whether the chemotherapy drug docetaxel, which increases survival in metastatic prostate cancer, can improve the cure rate in these patients.
In a new study, investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, a meta-analysis of five prospective randomized clinical trials (RCTs) found that adding docetaxel to standard-of-care (SOC) treatment was associated with a 70% reduction in death from prostate cancer-specific ...
Pet ownership may contribute to health care barriers for people with HIV
2023-11-01
People living with HIV may face hard choices when balancing their own health needs with caring for a pet, a study led by a University of Florida College of Public Health and Health Professions researcher finds.
For the study, which appears in the journal PLOS ONE, 36% of people with HIV who own pets reported delaying health care, not seeking it or said they expect to do so in the future. Financial and other resource concerns, including not having access to pet sitting or boarding services, are among the leading factors that may contribute to health care barriers among pet owners ...
Test detects co-infection by novel species of parasite in severe cases of visceral leishmaniasis
2023-11-01
In recent years, physicians and scientists in parts of Brazil where visceral leishmaniasis (VL) is endemic have seen rising numbers of cases of co-infection by Leishmania infantum and Crithidia, also a protozoan but hitherto believed to be a mosquito parasite that cannot infect humans or other mammals. Accurate diagnosis is hindered by a lack of simple specific tests (more at: https://agencia.fapesp.br/42072 and https://agencia.fapesp.br/31581).
To accelerate and facilitate detection of the pathogens involved, supporting appropriate decisions regarding treatment, researchers at the Federal University of São Carlos (UFSCar) have developed a PCR test ...
Dr. Zainab Mahmoud to receive the 2023 Dr. Nanette K. Wenger Research Goes Red® Award
2023-11-01
DALLAS, Nov. 1, 2023 – The American Heart Association will present the 2023 Dr. Nanette K. Wenger Research Goes Red® Award to Zainab Mahmoud, M.D., M.Sc., of Washington University School of Medicine in St. Louis. This award will be presented during the opening session of the Association’s Scientific Sessions 2023 on Saturday, Nov. 11. The meeting, to be held in Philadelphia, Saturday, Nov. 11 through Monday, Nov. 13, is a premier global exchange of the latest scientific advancements, ...
Lepore chosen to lead Public Policy & Aging Report
2023-11-01
The Gerontological Society of America (GSA) — the nation’s largest interdisciplinary organization devoted to the field of aging — has named Michael Lepore, PhD, of the University of Massachusetts (UMass) Amherst as the next editor-in-chief of the journal Public Policy & Aging Report, effective January 2024.
“I am honored to serve as editor-in-chief of Public Policy & Aging Report, which for nearly 30 years has provided non-partisan analyses of aging-related policy issues,” Lepore said. “This venerable journal has been a mainstay of my training and professional ...
Dr. Mary McGrae McDermott to be awarded the 2023 Clinical Research Prize
2023-11-01
DALLAS, Nov. 1, 2023 — The American Heart Association will present the 2023 Clinical Research Prize to Mary McGrae McDermott, M.D., FAHA, of Northwestern University’s Feinberg School of Medicine in Chicago. The Clinical Research Prize is awarded annually to physicians or scientists who are advancing clinical science in support of the Association’s mission.
Dr. McDermott has dedicated her career to advancing medical knowledge of peripheral artery disease (PAD). She will be recognized during the presidential session on Sunday, Nov. 12, 2023 at the Association’s Scientific Sessions ...
Dr. Olugbenga Ogedegbe to receive the 2023 Population Health Research Prize
2023-11-01
DALLAS, Nov. 1, 2023 — The American Heart Association will present its 2023 Population Health Research Prize to Olugbenga “Gbenga” Ogedegbe, M.D., M.P.H., FAHA, of New York University’s Grossman School of Medicine. He will be recognized during the presidential session of the Association’s Scientific Sessions 2023 on Sunday, Nov. 12. The meeting will be held in Philadelphia, Saturday, Nov. 11 through Monday, Nov. 13 and is a premier global exchange of the latest scientific advancements, research and evidence-based clinical practice updates in cardiovascular science.
Dr. ...
Dr. Marc A. Pfeffer to be receive the 2023 Eugene Braunwald Academic Mentorship Award
2023-11-01
DALLAS, Nov. 1, 2023 — The American Heart Association will present its 2023 Eugene Braunwald Academic Mentorship Award to Marc A. Pfeffer, M.D., Ph.D., FAHA, of Harvard Medical School and Brigham and Women’s Hospital. The Eugene Braunwald Academic Mentorship Award will be recognized during the Presidential Session on Sunday, Nov. 12, 2023, at the Association’s Scientific Sessions 2023. The meeting, to be held in Philadelphia, Saturday, Nov. 11 through Monday, Nov. 13, is a premier global exchange of the latest scientific advancements, research and evidence-based clinical practice updates in cardiovascular science.
The Eugene Braunwald Academic ...
What happens when cats get fat? Scientists weigh in
2023-11-01
URBANA, Ill. – Cat owners want Kitty to be happy, but providing an abundance of food and snacks can have unintended consequences. Feline obesity is on the rise, impacting the health, longevity, and wellbeing of cats. A new study from the University of Illinois Urbana-Champaign looks at what happens in the digestive system and gut microbiota when cats eat too much.
“About 60% of cats in the U.S. are overweight, which can lead to health problems such as diabetes and chronic inflammation. While many studies have investigated feline weight loss, there has been little focus on the opposite process, ...
Dr. Marlene Rabinovitch to receive the 2023 Research Achievement Award
2023-11-01
DALLAS, Nov. 1, 2023 – The American Heart Association will present its 2023 Research Achievement Award to Marlene Rabinovitch, M.D., of Stanford University. The Research Achievement Award will be recognized during the Presidential Session on Sunday, Nov. 12, 2023, at the Association’s Scientific Sessions 2023. The meeting, to be held in Philadelphia, Saturday, Nov. 11 through Monday, Nov. 13, is a premier global exchange of the latest scientific advancements, research and evidence-based clinical practice updates in cardiovascular science.
Throughout her nearly 40-year career as a physician scientist, Dr. Rabinovitch’s research ...
Dr. Yibin Wang of Duke-NUS to receive the 2023 Basic Research Prize
2023-11-01
DALLAS, Nov. 1, 2023 — The American Heart Association will present its 2023 Basic Research Prize to Yibin Wang, Ph.D., FAHA, of Duke-NUS Medical School in Singapore and Duke University School of Medicine, Durham, NC. He will be recognized during the Presidential Session of the Association’s Scientific Sessions 2023 on Sunday, Nov. 12. The meeting, to be held in Philadelphia, Saturday, Nov. 11 through Monday, Nov. 13, is a premier global exchange of the latest scientific advancements, research and evidence-based clinical practice updates in cardiovascular science.
Dr. ...
NASA’s Sandra Irish wins 2023 Society of Women Engineers Award
2023-11-01
Sandra Irish, mechanical systems lead structures engineer for NASA’s James Webb Space Telescope, has been selected to receive the Society of Women Engineers (SWE) Resnik Challenger Medal Award for her visionary contributions to the development, testing, transport, and launch of NASA’s premier space telescope since 2006. The medal was awarded during the World’s Largest Conference for Women in Engineering and Technology or WE23, which took place Oct. 26-28 in Los Angeles.
As an engineer at NASA’s Goddard Space Flight Center in Greenbelt, Maryland, for over 40 years, Irish’s mechanical systems expertise has helped ...
From soft tissue to stiff leather: Understanding the role of paxillin in liver fibrosis
2023-11-01
Currently, the United States lacks FDA-approved treatments for liver fibrosis, highlighting the critical need to understand the cellular biology and pathways associated with this condition.
In a recent study led by Don Rockey, M.D., the director of the Digestive Disease Research Core Center, and Nour Hijazi, an M.D.-Ph.D. student at the Medical University of South Carolina, significant progress has been made in understanding a pathway contributing to liver fibrosis. Their findings, highlighting a potential novel therapeutic ...
UArizona researchers examine the relationship between loneliness and being alone
2023-11-01
In a world filled with endless connections and constant communication, the relationship between loneliness and aloneness is not always clear. Now, University of Arizona researchers have analyzed that relationship – and found that they are two different things that are not closely correlated.
People don't feel lonely until they spend three-quarters of their time alone, the study found. However, when their alone time goes beyond 75%, it becomes difficult for them to avoid feelings of loneliness.
Published in the Journal of Research in Personality in September, the study also ...
Does your neighborhood affect your care after a stroke?
2023-11-01
EMBARGOED FOR RELEASE UNTIL 4 P.M. ET, WEDNESDAY, NOVEMBER 1, 2023
MINNEAPOLIS – People who live in neighborhoods with lower socioeconomic status are less likely to receive clot-busting medications or undergo clot-removing procedures after they have a stroke than people who live in neighborhoods with higher socioeconomic status, according to a study published in the November 1, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
“These treatments can greatly reduce death and ...
Parkinson disease and normal aging
2023-11-01
“Our principal component analyses showed a significant relationship between centro-cingulate cholinergic afferent changes and age in our Parkinson disease subjects.”
BUFFALO, NY- November 1, 2023 – A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, “Cholinergic centro-cingulate network in Parkinson disease and normal aging.”
In their new perspective, researchers Nicolaas I. Bohnen, Sygrid van der ...
Harold Hwang awarded 2024 McGroddy Prize for discovering exotic new materials
2023-11-01
The marvels of modern technology – computers that fit in your hand, internet-connected refrigerators, and self-driving cars – are only possible thanks to the magic of materials like silicon. Likewise, the sci-fi gadgets of tomorrow will spring from the exotic new materials scientists are discovering today.
Harold Hwang, a physicist at the Department of Energy's SLAC National Accelerator Laboratory and Stanford University, has brought this future closer by sandwiching carefully crafted materials together and seeing what happens where they touch. His experimentation has uncovered a host of compounds with surprising ...
University of Cincinnati study: Strawberry consumption may reduce dementia risk for middle-aged individuals
2023-11-01
New research from the University of Cincinnati found that daily strawberry consumption could help reduce the risk of dementia for certain middle-aged populations.
The research was recently published in the journal Nutrients.
Research background
In 2022, UC’s Robert Krikorian, PhD, and his team published research that found adding blueberries to the daily diets of certain middle-aged populations may lower the chances of developing late-life dementia. He said the current research into strawberries is an extension to the blueberry research.
“Both strawberries and blueberries contain antioxidants called anthocyanins, ...
November issues of American Psychiatric Association journals cover new insights in psychotic disorders, barriers to addiction treatment, bipolar disorder treatment, and more
2023-11-01
WASHINGTON, D.C., Nov. 1, 2023 — The latest issues of three American Psychiatric Association journals, The American Journal of Psychiatry, Psychiatric Services and Focus, are now available online.
The November issue of The American Journal of Psychiatry provides insights into psychotic disorders, such as the altered neurodevelopment and early symptom presentation associated with the risk of developing schizophrenia; racial and ethnic disparities in diagnosis of psychotic episodes; and predictors of first psychotic episodes and its treatment. Highlights include:
A Functional Connectome-Based Neural Signature ...
Markey Cancer Center study provides valuable insights into drivers of cancer risk
2023-11-01
LEXINGTON, Ky. (Oct. 31, 2023) — As people age, the DNA in their cells begins to accumulate genetic mutations. Mosaic chromosomal alterations (mCAs), a category of mutations acquired in blood cells, are linked with a 10-fold increased risk of developing blood cancer.
mCAs hold promise as a tool to identify people at high risk of developing certain cancers and diseases, but they have not yet been studied among a large, diverse cohort of people – a critical step required before such testing can be developed.
University of Kentucky Markey Cancer Center researcher Yasminka A. Jakubek, ...
New NIH research looks at life satisfaction in pandemic-era teens with mental health histories
2023-11-01
Collaborative ECHO Cohort research led by Phillip Sherlock, PhD; Maxwell Mansolf, PhD; and Courtney Blackwell, PhD of Northwestern University investigates the COVID-19 pandemic’s impacts on adolescents’ mental health. The findings suggest that some teens with a history of depression, anxiety, autism, and ADHD experienced more severe impacts than those without. This research, titled “Life Satisfaction for Adolescents with Developmental and Behavioral Disabilities during the COVID-19 Pandemic,” is published in Pediatric Research.
Although researchers ...
Giant dinosaur carcasses might have been important food sources for Jurassic predators
2023-11-01
Carnivorous dinosaurs might have evolved to take advantage of giant carcasses, according to a study published November 1, 2023 in the open-access journal PLOS ONE by Cameron Pahl and Luis Ruedas of Portland State University, Oregon and colleagues.
Carnivorous dinosaurs lived in ecosystems rich with both living and dead prey. The authors hypothesize that giant carcasses, like those of sauropod dinosaurs, might have provided a major source of food for large carnivores. To test this hypothesis, the researchers created an agent-based model, a simplified virtual simulation of a dinosaur ecosystem. This model was based on the ancient fauna of the Jurassic-aged ...
Game performance of immigrant NBA players might suffer in context of far-right political support
2023-11-01
During the 2020-2021 season of the National Basketball Association (NBA), which took place during Donald Trump’s failed bid at re-election, immigrant players for teams in regions with stronger far-right political sentiments were more likely to make game errors—highlighting the possible detrimental effects of such views on immigrant workplace performance. Benjamin Korman and Florian Kunze of the University of Konstanz, Germany, present these findings in the open-access journal PLOS ONE on November 1.
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