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Black summer bushfires in Australia wiped $2.8 billion from tourism supply chain

Black summer bushfires in Australia wiped $2.8 billion from tourism supply chain
2024-01-31
A first of its kind study of the 2019-2020 ‘Black Summer’ bushfires in Australia has revealed that the tourism industry nationwide took an immediate hit of $2.8 billion in total output to its broader supply chains and almost 7300 jobs disappeared nationwide. The fires four years ago triggered widespread tourism shutdowns in many parts of the country in the lead up to the peak Christmas and New Year season, resulting in $1.7 billion direct losses to the tourism industry, which triggered the larger drop in supply chain output. “These results are an illustration of what can be expected in the future not only in Australia, but in other ...

Using computers to design proteins allows researchers to make tunable hydrogels that can form both inside and outside of cells

2024-01-31
When researchers want to study how COVID makes us sick, or what diseases such as Alzheimer's do to the body, one approach is to look at what's happening inside individual cells. Researchers sometimes grow the cells in a 3D scaffold called a "hydrogel." This network of proteins or molecules mimics the environment the cells would live in inside the body. New research led by the University of Washington demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. The team created these hydrogels from protein building blocks designed using a computer to form a specific structure. These hydrogels exhibited similar mechanical properties ...

BIPOC individuals bear greater post-COVID burdens

2024-01-31
A study study published today reports that BIPOC individuals who were infected with COVID-19 experienced greater negative aftereffects in health and work loss than did similarly infected white participants. Despite similar symptom prevalence, Hispanic participants compared to non-Hispanic participants and BIPOC participants compared to white participants had more negative impacts following a COVID-19 infection in terms of health status, activity level and missed work, the authors wrote.  The findings appeared in the journal Frontiers ...

Anchoring single Co sites on bipyridine-based CTF for photocatalytic oxygen evolution

Anchoring single Co sites on bipyridine-based CTF for photocatalytic oxygen evolution
2024-01-31
Photocatalytic water splitting using semiconductors is regarded as a promising technique for producing hydrogen fuel from solar energy. The oxygen evolution half reaction has proven to be the bottleneck for photocatalytic overall water splitting owing to the high energy barrier and the sluggish kinetics. It is a big challenge to develop efficient photocatalysts for the advancement of water oxidation. Similar to graphene carbon nitride, π-stacked covalent triazine frameworks (CTFs) have gained much attention in photocatalytic water splitting in recent years. The fully conjugated structure with the regular channels in the crystalline network will provide defined pathways for ...

AI-powered app can detect poison ivy

AI-powered app can detect poison ivy
2024-01-31
Poison ivy ranks among the most medically problematic plants. Up to 50 million people worldwide suffer annually from rashes caused by contact with the plant, a climbing, woody vine native to the United States, Canada, Mexico, Bermuda, the Western Bahamas and several areas in Asia. It’s found on farms, in woods, landscapes, fields, hiking trails and other open spaces. So, if you go to those places, you’re susceptible to irritation caused by poison ivy, which can lead to reactions that require medical attention. Worse, most people don’t know ...

Up to three daily servings of kimchi may lower men’s obesity risk

2024-01-31
Eating up to three daily servings of the Korean classic, kimchi, may lower men’s overall risk of obesity, while radish kimchi is linked to a lower prevalence of midriff bulge in both sexes, finds research published in the open access journal BMJ Open.   Kimchi is made by salting and fermenting vegetables with various flavourings and seasonings, such as onion, garlic, and fish sauce.  Cabbage and radish are usually the main vegetables used in kimchi, which contains few calories and is rich in dietary fibre, microbiome enhancing lactic acid bacteria, vitamins, and polyphenols. Previously published experimental studies ...

Increase in annual cardiorespiratory fitness by 3%+ linked to 35% lower prostate cancer risk

2024-01-31
An increase in annual cardiorespiratory fitness by 3% or more is linked to a 35% lower risk of developing, although not dying from, prostate cancer, suggests research published online in the British Journal of Sports Medicine.   The findings prompt the researchers to conclude that men should be encouraged to improve their level of fitness to help lower their chances of getting the disease. There are relatively few known risk factors for prostate cancer, note the researchers. And while there’s good evidence for the beneficial effects of physical activity on ...

High quality diet in early life may curb subsequent inflammatory bowel disease risk

2024-01-31
A high quality diet at the age of 1 may curb the subsequent risk of inflammatory bowel disease, suggests a large long term study, published online in the journal Gut. Plenty of fish and vegetables and minimal consumption of sugar-sweetened drinks at this age may be key to protection, the findings indicate. A linked editorial suggests that it may now be time for doctors to recommend a ‘preventive’ diet for infants, given the mounting evidence indicative of biological plausibility. Cases of inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, are increasing globally. Although there is no obvious ...

Next government should declare a national health and care emergency

2024-01-31
The government in post after the election should declare a national health and care emergency, calling on all parts of society to help improve health, care, and wellbeing, say experts in the first report of The BMJ Commission on the Future of the NHS.   The new government should, in effect, relaunch the NHS with a renewed long term vision and plan, they argue. "The NHS has never seemed so embattled—and its core principle of ‘free to all at the point of use’ has never been so under threat,” said Kamran ...

Unprecedented success continues: 2023 employment gains for people with disabilities outshine those of counterparts without disabilities

Unprecedented success continues: 2023 employment gains for people with disabilities outshine those of counterparts without disabilities
2024-01-31
East Hanover, NJ – January 30, 2024 – Amidst the backdrop of a remarkable four-year streak of growth, the employment indicators for people with disabilities reached unprecedented milestones in 2023. This achievement stands in stark contrast to the experiences of people without disabilities who faced a more severe decline during the COVID-19 pandemic and a slower recovery, not surpassing their pre-pandemic employment levels until 2023. That’s according to the National Trends in Disability Employment (nTIDE) 2023 Year-End Special Edition, ...

Scientists pinpoint growth of brain’s cerebellum as key to evolution of bird flight

Scientists pinpoint growth of brain’s cerebellum as key to evolution of bird flight
2024-01-31
**EMBARGOED UNTIL 7:01 P.M. ET TUESDAY, JAN 30** Evolutionary biologists at Johns Hopkins Medicine report they have combined PET scans of modern pigeons along with studies of dinosaur fossils to help answer an enduring question in biology: How did the brains of birds evolve to enable them to fly? The answer, they say, appears to be an adaptive increase in the size of the cerebellum in some fossil vertebrates. The cerebellum is a brain region responsible for movement and motor control. The research findings are published in the Jan. 31 issue of the Proceedings of the Royal Society B. Scientists have long thought that the cerebellum should be important ...

Machine learning informs a new tool to guide treatment for acute decompensated heart failure

Machine learning informs a new tool to guide treatment for acute decompensated heart failure
2024-01-30
A recent study co-authored by Dr. Matthew Segar, a third-year cardiovascular disease fellow at The Texas Heart Institute and led by his research and residency mentor, University of Texas Southwestern Medical Center’s Dr. Ambarish Pandey, utilized a machine learning-based approach to identify, understand, and predict diuretic responsiveness in patients with acute decompensated heart failure (ADHF). The study “A Phenomapping Tool and Clinical Score to Identify Low Diuretic Efficiency in Acute Decompensated ...

Clear legal rules about the use of sperm and eggs in fertility treatment must remain to protect the vulnerable, study says

2024-01-30
  Clear legal rules outlining the use of the sperm and eggs of those who are incapacitated must remain in place to protect the vulnerable from being involved in fertility treatment without their consent, a new study says. There are strict laws in England and Wales involving the use of reproductive materials, but the research outlines how recent court cases have weakened this existing rigorous consent regime. It warns this could create a common law exception to informed consent, leaving the current law in a delicate position. The research says it is “not outside the realms of possibility” that some people may try to take ...

New interview with Eric Topol, MD, on the state of artificial intelligence in precision oncology

New interview with Eric Topol, MD, on the state of artificial intelligence in precision oncology
2024-01-30
An interview with Eric J. Topol, MD, a world-renowned cardiologist, best-selling author of several books on personalized medicine, and the founder and director of the Scripps Research Translational Institute in La Jolla, California, has been published. in the new peer-reviewed journal, AI in Precision Oncology. Dr. Topol is an advocate for using digital technologies and artificial intelligence in health care. click here to read the interview now. Douglas Flora, MD, Editor-in-Chief of AI in Precision Oncology, interviewed Dr. ...

Rotman School Professor named to Thinkers50 Radar Class

Rotman School Professor named to Thinkers50 Radar Class
2024-01-30
Rotman School Professor Named to Thinkers50 Radar Class Toronto – Maja Djikic, an associate professor of organizational behaviour and human resource management at the University of Toronto’s Rotman School of Management, has been named to the Thinkers50 Radar class for 2024. Announced every January, the Thinkers50 Radar identifies a cohort of 30 up-and-coming thinkers from around the world whose ideas have the potential to make an important impact on management thinking in the future. A personality psychologist specializing in adult development, Prof. Djikic is executive director of the Self-Development Lab at the Rotman School, which provides ...

Researchers find early symptoms of psychosis spectrum disorder in youth higher than expected

Researchers find early symptoms of psychosis spectrum disorder in youth higher than expected
2024-01-30
A new study co-led by Associate Professor Kristin Cleverley of the Lawrence Bloomberg Faculty of Nursing has found evidence that Psychosis Spectrum Symptoms (PSS) are often present in youth accessing mental health services. From a profile of the initial 417 youth aged 11-24 participating in the study, 50 per cent were shown to meet the threshold for Psychosis Spectrum Symptoms, a number Cleverley says was higher than expected, meaning there is a large number of children with these symptoms accessing mental health services. Cleverley, ...

Pitt receives new grant to improve opioid use disorder treatment

Pitt receives new grant to improve opioid use disorder treatment
2024-01-30
PITTSBURGH – The University of Pittsburgh School of Pharmacy’s Program Evaluation and Research Unit (PERU) has received a five-year, $7.8 million grant from the National Institute on Drug Abuse to improve quality of care for patients with opioid use disorder across Pennsylvania.   The project will establish the Helping to End Addiction Long-term (HEALing) Measures Center at Pitt, which will focus on developing and implementing measurement-based care into 20 community opioid treatment programs across Pennsylvania with the goal of enhancing treatment ...

Researchers craft new way to make high-temperature superconductors – with a twist

2024-01-30
An international team that includes Rutgers University–New Brunswick scientists has developed a new method to make and manipulate a widely studied class of high-temperature superconductors. This technique should pave the way for the creation of unusual forms of superconductivity in previously unattainable materials. When cooled to a critical temperature, superconductors can conduct electricity without resistance or energy loss. These materials have intrigued physicists for decades because they can achieve a state of ...

Study suggests secret for getting teens to listen to unsolicited advice

2024-01-30
A new study may hold a secret for getting your teenager to listen to appreciate  your unsolicited advice. The University of California, Riverside, study, which included “emerging adults” — those in their late teens and early 20s — found teens will appreciate parents’ unsolicited advice, but only if the parent is supportive of their teens’ autonomy. Parents support autonomy by providing clear guidelines for limitations and rules that will be enforced. They ...

Tech inefficiencies, piles of (electronic) paperwork, and increased patient volume contribute to burnout of primary care physicians, study finds

2024-01-30
Burnout is an occupational phenomenon that results from chronic workplace stress, according to the World Health Organization. Burnout often includes emotional exhaustion, negative feelings or mental distance from one’s job, and a low sense of accomplishment at work. COVID-19 increased feelings of burnout in primary care physicians, and a new study, sought to understand primary care clinicians’ perspectives on burnout during the COVID-19 pandemic, the causes of burnout, and strategies to improve clinician well-being.  Inefficiencies of electronic health records systems and high levels of documentation contribute ...

XRCC1: A potential prognostic and immunological biomarker in low-grade gliomas

XRCC1: A potential prognostic and immunological biomarker in low-grade gliomas
2024-01-30
“We conducted a comprehensive investigation into the potential of XRCC1 as a valuable diagnostic and prognostic indicator in diverse cancer types.” BUFFALO, NY- January 30, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, “XRCC1: a potential prognostic and immunological biomarker in LGG based on systematic pan-cancer analysis.” X-ray repair cross-complementation ...

Functional bladder tissue regenerated using bone marrow cells

2024-01-30
Scientists from Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University succeeded in regenerating fully functional urinary bladder tissue in a long-term study utilizing a non-human primate model. This unique model initially created by the Sharma Research Group explores long term bladder tissue regeneration at both anatomical and physiological levels. The Group used a novel biodegradable scaffold seeded with stem and progenitor cells from the animal’s own bone marrow, which demonstrated a higher degree of success than intestinal segments ...

Tribal program takes addiction treatment on the road

2024-01-30
With the national opioid epidemic disproportionately affecting American Indians and Alaska Natives, a tribal confederation in Oregon decided to take matters into their own hands. The Confederated Tribes of Grand Ronde not only opened Oregon’s first tribally owned opioid treatment program in Salem in 2021, but a year later, the tribe also began what is believed to be the nation’s first tribally operated mobile medication unit. The mobile bus runs a daily circuit from the tribal reservation in Grand Ronde to McMinnville to Salem, seeing patients and dispensing medications directly to tribal members struggling with an opioid use disorder. The program appears ...

The emergence of successive SARS-CoV-2 variants of concern during 2020-22 created a need to understand the drivers of such growth

The emergence of successive SARS-CoV-2 variants of concern during 2020-22 created a need to understand the drivers of such growth
2024-01-30
The emergence of successive SARS-CoV-2 variants of concern during 2020-22 created a need to understand the drivers of such growth; this study uses a Bayesian model to reveal how a set of key covariates (the infecting variant, symptom status, age and number of prior exposures) affect viral kinetics at both individual and population levels   ##### In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology:   http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002463 Article Title: Combined analyses of ...

Mutations in the Cu-Zn superoxide dismutase 1 gene SOD1 can cause familial amyotrophic lateral sclerosis (fALS) in a process that involves dissociation of the SOD1 dimer

Mutations in the Cu-Zn superoxide dismutase 1 gene SOD1 can cause familial amyotrophic lateral sclerosis (fALS) in a process that involves dissociation of the SOD1 dimer
2024-01-30
Mutations in the Cu-Zn superoxide dismutase 1 gene SOD1 can cause familial amyotrophic lateral sclerosis (fALS) in a process that involves dissociation of the SOD1 dimer; this study shows that a novel cyclic thiosulfinate cross-linker has favorable drug-like properties and can stabilize the SOD1 dimer in vivo, with therapeutic implications for fALS ##### In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology: http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002462 Author ...
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