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Socialization for success: Two recent studies expand our understanding of how early social housing helps dairy calves thrive

2023-12-19
Philadelphia, December 19, 2023 – Dairy industry professionals continuously work to ensure the highest possible welfare for dairy calves, including fine-tuning their housing to improve overall health, well-being, and performance. Two new studies in JDS Communications are illuminating our understanding of paired housing in the critical newborn and pre-weaned stages of dairy lives by showing that housing designed to facilitate early socialization can build behavior skills, shape calf personalities, and ultimately, set up animals ...

Sirtuin 6 activation rescues the age-related decline in DNA damage repair in chondrocytes

Sirtuin 6 activation rescues the age-related decline in DNA damage repair in chondrocytes
2023-12-19
“[...] the biological mechanisms linking aging and osteoarthritis prevalence remain largely unknown.” BUFFALO, NY- December 19, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, “Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes.” While advanced age is widely recognized as the greatest risk factor for osteoarthritis (OA), the biological mechanisms behind this connection remain unclear. Previous work has ...

Innovative optical technique for simultaneously producing and shaping gigahertz burst pulses

Innovative optical technique for simultaneously producing and shaping gigahertz burst pulses
2023-12-19
The generation and manipulation of high-repetition pulses hold great promise across various applications, including high-speed photography, laser processing, and acoustic wave generation. Gigahertz (GHz) burst pulses, with intervals ranging from ~0.01 to ~10 nanoseconds, are particularly valued for visualizing ultrafast phenomena and improving laser processing efficiency. While methods for producing GHz burst pulses exist, challenges persist, such as low throughput of pulse energy, poor tunability of pulse intervals, and the complexity ...

3D material found to break down antidepressant that contaminates water bodies worldwide

2023-12-19
An article published in the Chemical Engineering Journal describes a strategy to produce a material based on zinc oxide (ZnO) capable of degrading sertraline, an antidepressant that has been detected, like other drugs, in groundwater worldwide and is considered an emerging pollutant. This kind of substance has certain physicochemical properties that hinder removal by conventional wastewater treatment methods. The research was supported by FAPESP and conducted in Brazil by scientists at the Center for Development of Functional Materials (CDMF), the Brazilian ...

High Performance Computing Center of the University of Stuttgart and Hewlett Packard Enterprise to build exascale supercomputer

High Performance Computing Center of the University of Stuttgart and Hewlett Packard Enterprise to build exascale supercomputer
2023-12-19
The University of Stuttgart and Hewlett Packard Enterprise (HPE) have announced an agreement to build two new supercomputers at the High-Performance Computing Center of the University of Stuttgart (HLRS). In the first stage, a transitional supercomputer, called Hunter, will begin operation in 2025. This will be followed in 2027 with the installation of Herder, an exascale system that will provide a significant expansion of Germany’s high-performance computing (HPC) capabilities. Hunter and Herder will offer researchers ...

Gentle x-ray imaging of small living specimens

Gentle x-ray imaging of small living specimens
2023-12-19
X-ray imaging visualizes hidden structures and processes in living cells and organisms. The radiation that consists of highly energy-rich electromagnetic waves, however, has an ionizing effect and may damage the genetic material. This limits the possible observation period. While conventional X-ray images of soft tissue are of low contrast, phase contrast methods produce far better image contrasts at a reduced radiation dose. With higher resolution, however, gentle imaging becomes increasingly difficult, as a higher dose is required. Moreover, ...

Pushing compressed sensing to real-time edge applications

2023-12-19
Recently, a research team led by Prof. Sun Zhong at Peking University reported an analog hardware solution for real-time compressed sensing recovery, which has been published as an article titled "In-memory analog solution of compressed sensing recovery in one step" in Science Advances. In this work, a design based on a resistive memory (also known as memristor) array for performing instantaneous matrix-matrix-vector multiplication (MMVM) is first introduced. Based on this module, then an analog matrix computing circuit that solves compressed sensing (CS) recovery in one step (within few microseconds) is disclosed.  CS ...

The science behind snowflakes

The science behind snowflakes
2023-12-19
Tim Garrett has devoted his scientific career to characterizing snowflakes, the protean particles of ice that form in clouds and dramatically change as they fall to Earth. Now the University of Utah atmospheric scientist is unlocking the mystery of how snowflakes move in response to air turbulence that accompanies snowfall using novel instrumentation developed on campus. And after analyzing more than half a million snowflakes, what his team has discovered has left him astonished. Rather than something incomprehensibly complicated, predicting how snowflakes move proved to be surprisingly ...

COVID-19 infection causes teen’s vocal cord paralysis in first-of-its-kind case

2023-12-19
Physician-researchers from Mass Eye and Ear, a member of Mass General Brigham, report the first pediatric case of bilateral vocal cord paralysis after COVID-19 (SARS-CoV-2) infection. The patient, an otherwise healthy 15-year-old female, came to the emergency department at Massachusetts General Hospital with symptoms of respiratory distress nine days after diagnosis with SARS-CoV-2 infection. Examination with an endoscope revealed bilateral vocal cord paralysis, which is an immobility of both vocal cords found in the larynx or voice box. The researchers concluded that this paralysis was likely a downstream ...

Vervet monkeys follow different social “norms” and respond to “peer pressure,” new long-term study shows

Vervet monkeys follow different social “norms” and respond to “peer pressure,” new long-term study shows
2023-12-19
People living in different communities follow different social customs or norms. In some places, for instance, it might be standard practice to greet each person you see on the street, while in others that simply isn’t done. In some cases, such differences may even vary from one neighborhood to the next. Now researchers reporting in the journal iScience on December 19 have found similarly varied social traditions and styles among neighboring groups of vervet monkeys. “We report the existence of behavioral traditions of social customs in vervet ...

Would you like to groom me?

2023-12-19
Researchers at UNIL’s Department of Ecology and Evolution reveal the existence of social traditions in vervet monkeys. This work was published in iScience on December 19, 2023. British tits have learned from each other how to pierce the lids of milk bottles left on doorsteps. On the island of Koshima, Japanese macaques started washing sweet potatoes to rid them of sand. The animal realm is full of examples of traditions linked to food, tool use or hunting techniques that have spread within specific communities. However, few traditions of social nature, i.e. how individuals interact with each other, have been described. A ...

Snowflakes swirling in turbulent air as they fall through a laser light sheet. Credit: Singh et al.

Snowflakes swirling in turbulent air as they fall through a laser light sheet. Credit: Singh et al.
2023-12-19
WASHINGTON, Dec. 19, 2023 – A winter wonderland calls to mind piles of fluffy, glistening snow. But to reach the ground, snowflakes are swept into the turbulent atmosphere, swirling through the air instead of plummeting directly to the ground. The path of precipitation is complex but important to more than just skiers assessing the potential powder on their alpine vacation or school children hoping for a snow day. Determining snowflake fall speed is crucial for predicting weather patterns and measuring climate ...

Clinicians could be fooled by biased AI, despite explanations

2023-12-19
AI models in health care are a double-edged sword, with models improving diagnostic decisions for some demographics, but worsening decisions for others when the model has absorbed biased medical data. Given the very real life and death risks of clinical decision-making, researchers and policymakers are taking steps to ensure AI models are safe, secure and trustworthy—and that their use will lead to improved outcomes. The U.S. Food and Drug Administration has oversight of software powered by AI and machine learning used in health care and has issued guidance for developers. This includes a call to ensure the ...

Measuring the impact of AI in the diagnosis of hospitalized patients

2023-12-19
About The Study: Although standard artificial intelligence (AI) models improve diagnostic accuracy, systematically biased AI models reduced diagnostic accuracy, and commonly used image-based AI model explanations did not mitigate this harmful effect in this multicenter randomized clinical vignette survey study involving hospitalist physicians, nurse practitioners, and physician assistants from 13 states.  Authors: Michael W. Sjoding, M.D., of the University of Michigan Medical School, and Jenna Wiens, Ph.D., of the University of Michigan, Ann Arbor, are the corresponding authors. To ...

Disparities in preoperative goals of care documentation in veterans

2023-12-19
About The Study: In this study of 13,000 patients, few patients undergoing surgical procedures completed preoperative life-sustaining treatment documentation, with disparities in documentation rates based on race, ethnicity, rurality of patient residence, history of mental health disability, and access to high-volume facilities within a Veterans Affairs cohort. Authors: Adela Wu, M.D., of the U.S. Department of Veterans Affairs, in Palo Alto, California is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi: ...

Screening for social determinants of health during primary care and emergency department encounters

2023-12-19
About The Study: This study found that patients screened in the emergency department (ED) were more likely to screen positive for Social Determinants of Health (SDOH) needs, which is not surprising given utilization patterns. Patients with SDOH needs have limited health care access and are more likely to use the ED than primary care. Although primary care–based screening found lower SDOH needs relative to the ED, primary care may be better optimized to follow and ultimately address SDOH needs. Authors: Stacie ...

Study uncovers major hidden human-driven bird extinctions

Study uncovers major hidden human-driven bird extinctions
2023-12-19
Humans have wiped out around 1,400 bird species – twice as many as previously thought – with major implications for the ongoing biodiversity crisis, a new study has found. Many of the world’s islands were previously untouched paradises, but the arrival of people to places like Hawaii, Tonga and the Azores led, over time, to far-reaching impacts including deforestation, overhunting and the introduction of invasive species. Consequently, bird species were wiped out. While the demise of many birds since the 1500s has been recorded, our knowledge of the fate of species before this relies on fossils, ...

Promising new treatment for a common hereditary nerve disease

Promising new treatment for a common hereditary nerve disease
2023-12-19
Researchers from Tokyo Medical and Dental University (TMDU) develop a genome-editing technique that reduces disease-causing proteins and related issues in cells from a patient with Charcot–Marie–Tooth disease type 1A Tokyo, Japan – Scientific advances in the last century have changed our world significantly. For example, the world of genetics has opened doors to a myriad of possibilities: augmented human capabilities, cures for diseases, and even changes to the course of evolution. In a study published last month in Communications Medicine, researchers from Tokyo Medical and Dental University (TMDU) have unveiled a groundbreaking genome-editing technique. This ...

Moderation surpasses excess

Moderation surpasses excess
2023-12-19
Kyoto, Japan -- Down syndrome, a congenital disorder stemming from abnormal cell division and differentiation, is most common in newborns fated to neurodevelopmental delays and other health complications. The genetic defect causes the dysfunction of the protein kinase DYRK1A, which is encoded on chromosome 21 and is deeply associated with both Down syndrome and autism spectrum disorder. DYRK1A has attracted attention as a target molecule for treating various diseases, but specific cellular mechanisms regulating ...

Linking genes and brain circuitry in anxiety disorders

Linking genes and brain circuitry in anxiety disorders
2023-12-19
Kyoto, Japan – December 2023   Anxiety disorders (ADs) affect more than 280 million people worldwide, making them one of the most common mental health conditions. ADs have a genetic basis as seen from inheritance in families, and people with one subtype of AD tend to have another subtype, suggesting a shared genetic basis. Although the brain circuitry involved in ADs has been identified, its link with gene expression remains unclear. Two researchers at Kyoto University in Japan set out to uncover this link and found two gene clusters expressed in ...

A bacterial toolkit for colonizing plants

2023-12-19
Using a novel experimental approach, Max Planck researchers have discovered a core set of genes required by commensal bacteria to colonize their plant hosts. The findings may have broad relevance for understanding how bacteria establish successful host–commensal relationships. Plants are colonized by an enormous variety of microorganisms, including bacteria, archaea and fungi, that form complex communities, or microbiomes, on their roots and organs. Although invisible to the naked eye, the importance of these tiny inhabitants should not be underestimated. They play a crucial role in plant nutrition, influence the health of plants, strengthen their tolerance to stress factors such as ...

Study provides new insight into low social determinants of health screening rates

2023-12-19
A new study provides the latest data on the low rates for screening and documenting Social Determinants of Health (SDOH) in healthcare settings. SDOHs are a person's social, environmental and economic conditions highly correlated with their health outcomes. This includes unemployment, homelessness and illiteracy, among many other factors. Although SDOHs can contribute to a more comprehensive understanding of a patient's health and inform important policy changes, clinical offices fall short of tracking this information. To better understand ...

FlexTech: A new era in flexible electronics research

FlexTech: A new era in flexible electronics research
2023-12-19
On December 9, 2023, the 5th International Conference on Flexible Electronics (ICFE 2023) was held in Hangzhou, China. The international academic journal, FlexTech, was officially inaugurated at this conference. FlexTech is an initiative led by Tsinghua University, with academic support from the Laboratory of Flexible Electronics Technology Laboratory, Tsinghua University. This journal is co-published by Tsinghua University Press and John Wiley & Sons, Inc. The editorial board of FlexTech is under the distinguished leadership of Professor Xue ...

Why do people age differently?

2023-12-19
CLEVELAND—Throughout our lives, changes in our DNA, called genetic mutations, occur in every healthy cell of the human body—mutations which have long been thought to be an important reason why our bodies age. But it’s not known whether some people accumulate mutations at a faster or slower rate with age, and whether those differences might predict how long we live and the risk for aging-related diseases like cancer. With a $3.5 million research project grant from the National Institutes of Health (NIH), Jonathan Shoag, a surgeon-scientist at the Case Western Reserve University School of Medicine and urologic oncologist at ...

Ali Khademhosseini named as 2023 National Academy of Inventors Fellow

Ali Khademhosseini named as 2023 National Academy of Inventors Fellow
2023-12-19
(LOS ANGELES) – December 18, 2023 - The National Academy of Inventors (NAI) has named Ali Khademhosseini, Ph.D., Director and CEO of the Terasaki Institute for Biomedical Innovation (TIBI), as a 2023 National Academy of Inventors Fellow. This distinctive honor is the highest professional award that is exclusively bestowed upon inventors. The Academy has chosen to honor him for his achievements and contributions to the innovation ecosystem, which vastly influences science, society, and the global economy. Dr. Khademhosseini will be formally recognized at the NAI thirteenth annual meeting on June 18, 2024, where he will be presented with a medal by a senior official from the United States ...
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