PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Inner ear hair cell regeneration: A look from the past to the future

2013-09-12
(Press-News.org) Since Moffat and Ramsden for the first time discovered the possibility of the auditory system in humans in 1977, over the last two decades, great progress has been made in physiopathological research on neurosensory hearing loss. Jørgensen and Mathiesen were the first authors to note the capacity for regeneration of the normal vestibular epithelium in adult Australian parrots. Later, Roberson et al studied the normal vestibular epithelium of 12-day-old white Leghorn chicks using tritiated thymidine and bromodeoxyuridine. Francisco Santaolalla and colleagues from Basurto University Hospital, Spain review literatures on theory and clinical application of inner ear sensory hair cell regeneration. This review, published in the Neural Regeneration Research (Vol. 8, No. 24, 2013), the use of stem cells, gene therapy and neurotrophic factors has important role in regeneration of inner ear hair cells. Cochlear gene therapy has been successfully used in the treatment of neurosensory hearing loss and other inner ear disorders. Greatest progress will be achieved, in the near future, in the regeneration of hair cells after use of atonal homolog 1 gene delivered by viral vectors and this may become the best clinical treatment method of certain types of hearing loss.

### Article: " Inner ear hair cell regeneration: a look from the past to the future," by Francisco Santaolalla1, 2, Carlos Salvador1, Agustín Martínez2, Jose María Sánchez2, Ana Sánchez del Rey2 (1 Department of Otorhinolaryngology, Basurto University Hospital, Bilbao, Bizkaia, Spain; 2 Department of Dermatology, Ophthalmology and Otorhinolaryngology, School of Medicine, University of the Basque Country (UPV/EHU), Bilbao, Bizkaia, Spain)

Santaolalla F, Salvador C, Martínez A, Sánchez JM, Sánchez del Rey A. Inner ear hair cell regeneration: a look from the past to the future. Neural Regen Res. 2013;8(24):2284-2289.

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
http://www.nrronline.org/ Full text: http://www.sjzsyj.org/CN/article/downloadArticleFile.do?attachType=PDF&id=701


ELSE PRESS RELEASES FROM THIS DATE:

Researchers hit virtual heads to make safer games

2013-09-12
PULLMAN, Wash. – Two nearly identical softballs, both approved for league play, can have dramatically different effects when smacked into a player's head. Those are the findings from a study conducted by Professor Lloyd Smith in the School of Mechanical and Materials Engineering and project engineer Derek Nevins that they will present at the Asia Pacific Congress on Sports Technology later this month in Hong Kong. Their work was published in the journal, Procedia Engineering. Smith's group developed a unique model of a softball that they electronically throw at a virtual ...

The efficient choice among combustion engines

2013-09-12
Researchers at ETH Zurich have developed an internal combustion engine that emits less than half the CO2 compared to a regular engine without compromising performance. This corresponds to fuel consumption of less than 2.4l per 100km. This natural gas-diesel hybrid engine is based on a system of sophisticated control engineering. The global energy markets are changing. New extraction methods are tapping into oilfields and natural gas deposits that have been inaccessible until now. The US, for example, is able to cover up to 83% of its total energy needs today; the government ...

Delaying climate policy would triple short-term mitigation costs

2013-09-12
Higher costs would in turn increase the threshold for decision-makers to start the transition to a low-carbon economy. Thus, to keep climate targets within reach it seems to be most relevant to not further postpone mitigation, the researchers conclude. "The transitional economic repercussions that would result if the switch towards a climate-friendly economy is delayed, are comparable to the costs of the financial crisis the world just experienced," lead-author Gunnar Luderer says. The later climate policy implementation starts, the faster – hence the more expensive – ...

Pulsating dust cloud dynamics modeled

2013-09-12
The birth of stars is an event that eludes intuitive understanding. It is the collapse of dense molecular clouds under their own weight that offers the best sites of star formation. Now, Pralay Kumar Karmakar from the Department of Physics at Tezpur University, Assam province, India, and his colleague have proposed a new model for investigating molecular cloud fluctuations at sites of star formation and thus are able to study their pulsational dynamics, in a paper published in EPJ D. Dust molecular clouds are a type of astrophysical plasmas, which are composed of a primordial ...

More than just type 1 or type 2: DiMelli study points to different forms of diabetes

2013-09-12
The DiMelli (Diabetes Mellitus Incidence Cohort Registry) study examines the frequency and characteristics of diabetes phenotypes in children and young adults below the age of 20. The study was commissioned to investigate the increasing incidence of diabetes mellitus, particularly in childhood and early adulthood. The project is funded by the German Center for Diabetes Research (DZD). Bioprobe measurements were performed centrally by the Central Medical Laboratory (LMZ) at the Helmholtz Zentrum München (HMGU) so as to guarantee the high quality and comparability of laboratory ...

Codeine could increase users' sensitivity to pain

2013-09-12
Using large and frequent doses of the pain-killer codeine may actually produce heightened sensitivity to pain, without the same level of relief offered by morphine, according to new research from the University of Adelaide. Researchers in the Discipline of Pharmacology have conducted what is believed to be the world's first experimental study comparing the pain relieving and pain worsening effects of both codeine and morphine. The University's Professor Paul Rolan, who is also a headache specialist at the Royal Adelaide Hospital, says codeine has been widely used as ...

Dogs' behavior could help to design social robots

2013-09-12
Designers of social robots, take note. Bring your dog to the lab next time you test a prototype, and watch how your pet interacts with it. You might just learn a thing or two that could help you fine-tune future designs. So says Gabriella Lakatos of the Hungarian Academy of Science and Eötvös Loránd University, lead author of a study¹ published in Springer's journal Animal Cognition that found that man's best friend reacts sociably to robots that behave socially towards them, even if the devices look nothing like a human. This animal behavior study tested the reaction ...

Study explores complex physical oceanography in East China Sea

2013-09-12
Just days before a team of researchers from Woods Hole Oceanographic Institution (WHOI) and National Taiwan University set out to conduct fieldwork in the East China Sea, Typhoon Morakot—one of the most destructive storms ever to hit Taiwan—made landfall on the island, causing widespread damage and drastically altering the flow of water along the nearby continental shelf. The typhoon, which struck in Aug. 2009, caused catastrophic damage in Taiwan, killing several hundred people and dropping up to 2 meters of rain in just 5 days in the mountains. In their work to understand ...

Uros people of Peru and Bolivia found to have distinctive genetic ancestries

2013-09-12
RESEARCH CONCLUSIONS: New genetic research led by the Genographic Project consortium shows a distinctive ancestry for the Uros populations of Peru and Bolivia that predates the arrival of the Spanish conquistadores and may date back to the earliest settlement of the Altiplano, or high plain, of the central Andes some 3,700 years ago. Despite the fact that the Uros today share many lineages with the surrounding Andean populations, they have maintained their own divergent genetic ancestry. WHO ARE THE UROS?: The Uros are a self-identified ethnic group, about 2,000 ...

Women have higher rate of spontaneous clearance of hepatitis C virus

2013-09-12
A study of patients infected with acute hepatitis C virus (HCV) infection found that women had higher rates of spontaneous viral clearance—undetectable levels of the virus without initiating drug therapy. Findings published in Hepatology, a journal of the American Association for the Study of Liver Diseases, indicate that the gene IL28B (rs12979860) and HCV genotype 1 are also independent predictors of spontaneous HCV clearance. In 2011, there were 1,229 cases of acute HCV reported to the Centers for Disease Control and Infection (CDC), which represents a 44% increase ...

LAST 30 PRESS RELEASES:

Reality check: making indoor smartphone-based augmented reality work

Overthinking what you said? It’s your ‘lizard brain’ talking to newer, advanced parts of your brain

Black men — including transit workers — are targets for aggression on public transportation, study shows

Troubling spike in severe pregnancy-related complications for all ages in Illinois

Alcohol use identified by UTHealth Houston researchers as most common predictor of escalated cannabis vaping among youths in Texas

Need a landing pad for helicopter parenting? Frame tasks as learning

New MUSC Hollings Cancer Center research shows how Golgi stress affects T-cells' tumor-fighting ability

#16to365: New resources for year-round activism to end gender-based violence and strengthen bodily autonomy for all

Earliest fish-trapping facility in Central America discovered in Maya lowlands

São Paulo to host School on Disordered Systems

New insights into sleep uncover key mechanisms related to cognitive function

USC announces strategic collaboration with Autobahn Labs to accelerate drug discovery

Detroit health professionals urge the community to act and address the dangers of antimicrobial resistance

3D-printing advance mitigates three defects simultaneously for failure-free metal parts 

Ancient hot water on Mars points to habitable past: Curtin study

In Patagonia, more snow could protect glaciers from melt — but only if we curb greenhouse gas emissions soon

Simplicity is key to understanding and achieving goals

Caste differentiation in ants

Nutrition that aligns with guidelines during pregnancy may be associated with better infant growth outcomes, NIH study finds

New technology points to unexpected uses for snoRNA

Racial and ethnic variation in survival in early-onset colorectal cancer

Disparities by race and urbanicity in online health care facility reviews

Exploring factors affecting workers' acquisition of exercise habits using machine learning approaches

Nano-patterned copper oxide sensor for ultra-low hydrogen detection

Maintaining bridge safer; Digital sensing-based monitoring system

A novel approach for the composition design of high-entropy fluorite oxides with low thermal conductivity

A groundbreaking new approach to treating chronic abdominal pain

ECOG-ACRIN appoints seven researchers to scientific committee leadership positions

New model of neuronal circuit provides insight on eye movement

Cooking up a breakthrough: Penn engineers refine lipid nanoparticles for better mRNA therapies

[Press-News.org] Inner ear hair cell regeneration: A look from the past to the future