Early intervention by infectious diseases specialists saves lives, reduces costs

(Press-News.org) WASHINGTON, Sept. 26, 2013 – In a first-of-its-kind study to evaluate the impact of a medical specialty on patient outcomes, researchers found that hospitalized patients with severe infections such as meningitis and Clostridium difficile (C. diff.) are significantly less likely to die if they receive care from an infectious diseases specialist. The study, which analyzed nearly 130,000 Medicare patient cases, is now available online and will be published in the December 15 issue of Clinical Infectious Diseases.

According to the data, researchers at Avalere Health and the Infectious Diseases Society of America (IDSA) found that patients treated by infectious diseases (ID) specialists are 9 percent less likely to die in the hospital and 12 percent less likely to die after discharge. When an ID physician is consulted, patients experience an average 3.7 percent fewer days in an intensive care unit. The study also found that consultation with an ID specialist reduces the likelihood patients will be readmitted to the hospital within 30 days.

"Infectious diseases are the second leading cause of death worldwide. In an age where healthcare-acquired infections are linked to payment penalties and bundled payments leave little room for error, the impact of ID physicians is more critical than ever in providing high quality care," said Steven K. Schmitt, MD, FIDSA, chair of the IDSA's Clinical Affairs Committee, an ID physician at Cleveland Clinic and lead author of the study. "As the 'detectives' of the medical world, ID specialists have additional years of training and possess the expertise to quickly identify and treat potentially life-threatening infections."

In the study, researchers looked at a sample of Medicare patients who were hospitalized between Jan. 1, 2008 and Dec. 31, 2009 and had at least one of 11 serious but commonly treated infections: bacteremia, C. diff., central line associated bloodstream infections (CLABSI), bacterial endocarditis, human immunodeficiency virus (HIV)/opportunistic infections, meningitis, osteomyelitis, prosthetic joint infections, septic arthritis, septic shock, and vascular device infections. Matching patient characteristics, researchers compared the outcomes of 61,680 cases in which a hospitalized patient saw an ID specialist to 65,192 cases that did not involve an ID specialist.

The benefits of ID consultation are more pronounced when patients are seen earlier, researchers note. Patients seen by an ID physician within two days of being admitted to the hospital are 6 percent less likely to be readmitted to the hospital within 30 days of discharge compared to patients seen by an ID physician after the first two days. These patients also have an average 3.8 percent fewer days in the hospital, and their total Medicare costs are nearly 6.2 percent lower in the 30 days after discharge from the hospital.

"These findings are in line with healthcare reform efforts being implemented through the Affordable Care Act, which shows that including ID specialists in up-front care of patients provides better outcomes at lower costs," said Daniel McQuillen, MD, FIDSA, a member of the Infectious Diseases Society of America, ID physician at Lahey Hospital & Medical Center and study author. "Further, the association of ID specialist involvement with reduced readmission rates suggests an important role for the ID physician in transitions of care from the hospital to the community."

### About Infectious Diseases Specialists Infectious diseases specialists are physicians who have completed residency training in a specialty such as internal medicine or pediatrics and have undergone at least two to three years of additional, specialized training in infectious diseases. ID specialists play a critical role in the diagnosis, treatment and prevention of infections by collecting the patient's history; conducting a physical examination; selecting appropriate diagnostic testing; and managing appropriate antibiotic choice, duration of therapy, route of delivery, and adverse drug reactions. An estimated 7,500 board certified ID specialists are practicing in the United States today, which has grown from fewer than 1,000 physicians in the early 1980s.

ID specialists are commonly called upon in major public health crises, including outbreaks of emerging infectious diseases, to educate the public, define treatment, and help halt the spread of rapidly communicable illnesses.

Diseases that used to have high morbidity and mortality rates, such as polio, smallpox, measles, influenza, mumps, and rubella, have been significantly curtailed or eradicated thanks to traditional ID strategies of surveillance and immunization. The demand for ID specialists is increasing as the need for specialized care to treat, prevent and study HIV, viral hepatitis, influenza, antibiotic resistant infections, and the list of ever-evolving microbes that cause human diseases continues to grow.

A Centers for Disease Control and Prevention (CDC) report issued last week underscored the threat posed by antibiotic resistant infections, which are often managed by ID specialists. The report revealed that C. diff. alone accounts for more than 250,000 infections and at least 14,000 deaths per year. Given ID specialists' crucial role in the development and implementation of antimicrobial stewardship and infection programs, noted by CDC as essential to effectively combating this crisis, it's clear they are an important part of combating the spread of deadly antibiotic resistant infections.

Note: For a copy of the article, "Infectious Diseases Specialty Intervention is Associated with Decreased Mortality and Lower Healthcare Costs," to be published in the December 15 print issue of Clinical Infectious Diseases, please contact Jerica Pitts at (312) 558-1770 or jpitts@pcipr.com. Research for this study was funded by the Infectious Diseases Society of America (IDSA).

AT A GLANCE A study of nearly 130,000 cases of hospitalized Medicare patients treated for one of 11 common infections compared outcomes of those treated by an ID specialist to those who were not.

Hospitalized patients with severe infections are 12 percent less likely to die within 30 days if they receive care from an ID specialist.

The benefits are more pronounced when patients are seen by an ID specialist within two days of admission, minimizing hospital readmissions and lowering medical costs by 6 percent.

About IDSA The Infectious Diseases Society of America (IDSA) is an organization of physicians, scientists, and other health care professionals dedicated to promoting health through excellence in infectious diseases research, education, prevention, and patient care. The Society, which has more than 10,000 members, was founded in 1963 and is based in Arlington, VA. For more information, see http://www.idsociety.org.

About Avalere Health Avalere Health is an advisory services company whose core purpose is to create innovative solutions to complex healthcare problems. Based in Washington, DC, the firm delivers research, analysis, insight, and strategy for leaders in healthcare business and policy. Avalere's experts span 170 staff drawn from the federal government (e.g., CMS, OMB, CBO, and the Congress), Fortune 500 healthcare companies, top consultancies, and nonprofits. The firm offers deep substance in areas ranging from healthcare coverage and financing to the changing role of evidence in healthcare decision-making. For more information, visit avalerehealth.net. Follow Avalere Health on Twitter @avalerehealth.