PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Inner ear stem cells hold promise for restoring hearing

Inner ear stem cells hold promise for restoring hearing
2014-06-20
(Press-News.org) New Rochelle, NY, June 20, 2014—Spiral ganglion cells are essential for hearing and their irreversible degeneration in the inner ear is common in most types of hearing loss. Adult spiral ganglion cells are not able to regenerate. However, new evidence in a mouse model shows that spiral ganglion stem cells present in the inner ear are capable of self-renewal and can be grown and induced to differentiate into mature spiral ganglion cells as well as neurons and glial cells, as described in an article in BioResearch Open Access, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the BioResearch Open Access website.

Marc Diensthuber and coauthors from Goethe-University (Frankfurt, Germany), Justus-Liebig University (Giessen, Germany), Harvard Medical School and Massachusetts Eye and Ear Infirmary (Boston, MA), and Harvard University and MIT (Cambridge, MA), conclude that the self-renewing properties demonstrated by spiral ganglion stem cells make them a promising source of replacement cells for therapies designed to regenerate the neural structures of the inner ear in the article "Spiral Ganglion Stem Cells Can Be Propagated and Differentiated Into Neurons and Glia."

"These findings are particularly interesting as they show that spiral ganglion stem cells can be propagated in vitro," says BioResearch Open Access Editor Jane Taylor, PhD, MRC Centre for Regenerative Medicine, University of Edinburgh, Scotland. "These cells are normally poorly regenerated in the mammalian ear."

INFORMATION: About the Journal BioResearch Open Access is a bimonthly peer-reviewed open access journal led by Editor-in-Chief Robert Lanza, MD, Chief Scientific Officer, Advanced Cell Technology, Inc. and Editor Jane Taylor, PhD. The Journal provides a new rapid-publication forum for a broad range of scientific topics including molecular and cellular biology, tissue engineering and biomaterials, bioengineering, regenerative medicine, stem cells, gene therapy, systems biology, genetics, biochemistry, virology, microbiology, and neuroscience. All articles are published within 4 weeks of acceptance and are fully open access and posted on PubMed Central. All journal content is available on the BioResearch Open Access website.

About the Publisher Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many areas of science and biomedical research, including DNA and Cell Biology, Tissue Engineering, Stem Cells and Development, Human Gene Therapy, HGT Methods, and HGT Clinical Development, and AIDS Research and Human Retroviruses. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website (http://www.liebertpub.com).

Mary Ann Liebert, Inc.
140 Huguenot St., New Rochelle, NY 10801-5215
Phone: (914) 740-2100
(800) M-LIEBERT
Fax: (914) 740-2101
http://www.liebertpub.com

[Attachments] See images for this press release:
Inner ear stem cells hold promise for restoring hearing

ELSE PRESS RELEASES FROM THIS DATE:

Miriam Hospital researchers analyze AUDs, sexual behavior among South African men

2014-06-20
PROVIDENCE, R.I. – In a study of South African men who drink alcohol in informal drinking environments or "shebeens," researchers from The Miriam Hospital have found a high prevalence of Alcohol Use Disorder (AUD) that directly correlates to unprotected sex. Findings support the need for interventions targeting both alcohol and HIV-risk behaviors among South African men who drink alcohol in alcohol-serving venues. The study and its findings are published in the July issue of Drug and Alcohol Dependence. Lori A. Scott-Sheldon, Ph.D., lead author and researcher at The ...

Researchers find gene critical for development of brain motor center

2014-06-20
Ottawa – June 20, 2014 – In a report published today in Nature Communications, an Ottawa-led team of researchers describe the role of a specific gene, called Snf2h, in the development of the cerebellum. Snf2h is required for the proper development of a healthy cerebellum, a master control centre in the brain for balance, fine motor control and complex physical movements. Athletes and artists perform their extraordinary feats relying on the cerebellum. As well, the cerebellum is critical for the everyday tasks and activities that we perform, such as walking, eating and ...

New study explains how organs coordinate their development with the whole body

2014-06-20
This news release is available in Portuguese. This news release is available in Portuguese. A research group led by Christen Mirth at Instituto Gulbenkian de Ciência (Portugal) uncovered that the development of wings in fruit flies does not progress synchronously with the organism's development. Instead, it is coordinated with the whole body only at distinct 'milestones'. This study, published in the latest issue of the scientific journal PLOS Genetics*, helps explain how an organism facing environmental and physiological perturbations retains the ability to build ...

Greedy CEOs bad for business

Greedy CEOs bad for business
2014-06-20
Yes, Virginia, there is greed. Greedy managers. Corporate greed. Greedy behavior. In fact, a web database search shows you can find such phrases in the business press over 18,000 times, confirming the subject's popularity in everyday media. But you need not fear greed, Virginia, because believe it or not, you can moderate it. In a forthcoming article in the top-ranked Journal of Management, new research by University of Delaware assistant professor Katalin Takacs Haynes examines the effects of greed on shareholder wealth and looks at whether various contextual factors, ...

Children's Research Institute finds key to identifying, enriching mesenchymal stem cells

Childrens Research Institute finds key to identifying, enriching mesenchymal stem cells
2014-06-20
DALLAS – June 20, 2014 – The Children's Medical Center Research Institute at UT Southwestern (CRI) has identified a biomarker that enables researchers to accurately characterize the properties and function of mesenchymal stem cells (MSCs) in the body. MSCs are the focus of nearly 200 active clinical trials registered with the National Institutes of Health, targeting conditions such as bone fractures, cartilage injury, degenerative disc disease, and osteoarthritis. The finding, published in the journal Cell Stem Cell on June 19, significantly advances the field of MSC ...

IOM: Effectiveness of PTSD treatments provided by DOD & VA unknown

2014-06-20
WASHINGTON -- The U.S. Department of Defense and U.S. Department of Veterans Affairs should track the outcomes of treatment for post-traumatic stress disorder (PTSD) provided to service members and veterans and develop a coordinated and comprehensive strategy to do so, says a new congressionally mandated report from the Institute of Medicine. Without tracking outcomes, neither DOD nor VA knows whether it is providing effective or adequate PTSD care, for which they spent $294 million and more than $3 billion, respectively, in 2012. The report is the second of a two-phase ...

Researchers identify mitochondrial mutation linked to congenital myasthenic syndrome

2014-06-20
Amsterdam, NL, 20 June 2014 – Although significant progress has been made over the last 25 years to identify genetic abnormalities associated with congenital myasthenic syndromes (CMS), many patients remain genetically undiagnosed. A report in the inaugural issue of the Journal of Neuromuscular Diseases identifies a gene defect in mitochondria, specifically the citrate carrier SLC25A1, that may underlie deficits in neuromuscular transmission seen in two siblings. "While mitochondrial gene defects can cause a myriad of neurological disorders including myopathies and neuropathies, ...

Molecule regulates production of antibacterial agent used by immune cells

2014-06-20
Researchers have discovered how a protein molecule in immune cells promotes the production of nitric oxide, a potent weapon in the cells' arsenal to defend the body from bacterial attack. The protein may offer a target for reining in the inflammatory response, which must be able to fight infection without damaging tissue. The study was published in the Journal of Innate Immunity. NFATc3 is one of several related protein molecules known to play a role in regulating genes in the T and B cells of the immune system. Ravi Ranjan, research scientist at the University of Illinois ...

Benefits of PTSD treatment going unmeasured, says Institute of Medicine Report

Benefits of PTSD treatment going unmeasured, says Institute of Medicine Report
2014-06-20
VIDEO: IOM report out today demonstrates that the VA and US Department of Defense do not measure the effectiveness of treatment of post-traumatic stress disorder. Columbia University Mailman School of Public... Click here for more information. June 20, 2014 -- A report from the Institute of Medicine (IOM) finds that the U.S. Department of Defense (DOD) and U.S. Department of Veterans Affairs (VA) do not measure the effectiveness of treatment of post-traumatic stress disorder ...

New research reveals that emperor penguins are more willing to relocate

New research reveals that emperor penguins are more willing to relocate
2014-06-20
A new study led by the University of Minnesota offers new insights on the long-term future of emperor penguins by showing that the penguins may be behaving in ways that allow them to adapt to their changing environment better than we expected. Researchers have long thought that emperor penguins were philopatric, which means they would return to the same location to nest each year. The new research study used satellite images to show that penguins may not be faithful to previous nesting locations. Researchers involved in the new study found six instances in just three ...

LAST 30 PRESS RELEASES:

Call for papers: 14th Asia-Pacific Conference on Transportation and the Environment (APTE 2025)

A novel disturbance rejection optimal guidance method for enhancing precision landing performance of reusable rockets

New scan method unveils lung function secrets

Searching for hidden medieval stories from the island of the Sagas

Breakthrough study reveals bumetanide treatment restores early social communication in fragile X syndrome mouse model

Neuroscience leader reveals oxytocin's crucial role beyond the 'love hormone' label

Twelve questions to ask your doctor for better brain health in the new year

Microelectronics Science Research Centers to lead charge on next-generation designs and prototypes

Study identifies genetic cause for yellow nail syndrome

New drug to prevent migraine may start working right away

Good news for people with MS: COVID-19 infection not tied to worsening symptoms

Department of Energy announces $179 million for Microelectronics Science Research Centers

Human-related activities continue to threaten global climate and productivity

Public shows greater acceptance of RSV vaccine as vaccine hesitancy appears to have plateaued

Unraveling the power and influence of language

Gene editing tool reduces Alzheimer’s plaque precursor in mice

TNF inhibitors prevent complications in kids with Crohn's disease, recommended as first-line therapies

Twisted Edison: Bright, elliptically polarized incandescent light

Structural cell protein also directly regulates gene transcription

Breaking boundaries: Researchers isolate quantum coherence in classical light systems

Brain map clarifies neuronal connectivity behind motor function

Researchers find compromised indoor air in homes following Marshall Fire

Months after Colorado's Marshall Fire, residents of surviving homes reported health symptoms, poor air quality

Identification of chemical constituents and blood-absorbed components of Shenqi Fuzheng extract based on UPLC-triple-TOF/MS technology

'Glass fences' hinder Japanese female faculty in international research, study finds

Vector winds forecast by numerical weather prediction models still in need of optimization

New research identifies key cellular mechanism driving Alzheimer’s disease

Trends in buprenorphine dispensing among adolescents and young adults in the US

Emergency department physicians vary widely in their likelihood of hospitalizing a patient, even within the same facility

Firearm and motor vehicle pediatric deaths— intersections of age, sex, race, and ethnicity

[Press-News.org] Inner ear stem cells hold promise for restoring hearing