INFORMATION:
Article reference: Yue Li, Zhiyi Chen and Shuping Ge, Sonoporation: Underlying Mechanisms and Applications in Cellular Regulation. BIO Integration, 2021, https://doi.org/10.15212/bioi-2020-0028
BIO Integration is fully open access journal which will allow for the rapid dissemination of multidisciplinary views driving the progress of modern medicine.
As part of its mandate to help bring interesting work and knowledge from around the world to a wider audience, BIOI will actively support authors through open access publishing and through waiving author fees in its first years. Also, publication support for authors whose first language is not English will be offered in areas such as manuscript development, English language editing and artwork assistance.
BIOI is now open for submissions; articles can be submitted online at:
https://mc04.manuscriptcentral.com/bioi
Please visit http://www.bio-integration.org to learn more about the journal.
Editorial Board: https://bio-integration.org/editorial-board/
Please visit http://www.bio-integration.org to learn more about the journal.
Editorial Board: https://bio-integration.org/editorial-board/
BIOI is available on the IngentaConnect platform and at the BIO Integration website .
Submissions may be made using ScholarOne .
There are no author submission or article processing fees.
Follow BIOI on Twitter @JournalBio; Facebook and LinkedIn .
ISSN 2712-0074
eISSN 2712-0082
Keywords: Microbubble, multidisciplinary, reprogramming, sonoporation, ultrasound END
Sonoporation: Underlying mechanisms and applications in cellular regulation
2021-02-09
(Press-News.org) Announcing a new article publication for BIO Integration journal. In this review article the authors Yue Li, Zhiyi Chen and Shuping Ge from First Affiliated Hospital of University of South China, Hengyang, China and Tower Health and Drexel University, Philadelphia, PA, USA summarize current state of the art applications of microbubble-cell interactions and sonoporation effects to cellular functions.
Ultrasound combined with microbubble-mediated sonoporation has been applied to enhance drug or gene intracellular delivery. Sonoporation leads to the formation of openings in the cell membrane, triggered by ultrasound-mediated oscillations and destruction of microbubbles. Multiple mechanisms are involved in the occurrence of sonoporation, including ultrasonic parameters, microbubbles size, and the distance of microbubbles to cells. Recent advances are beginning to extend applications through the assistance of contrast agents, which allow ultrasound to connect directly to cellular functions such as gene expression, cellular apoptosis, differentiation, and even epigenetic reprogramming.
ELSE PRESS RELEASES FROM THIS DATE:
Nanocarriers in the enhancement of therapeutic efficacy of natural drugs
2021-02-09
Announcing a new article publication for BIO Integration journal. In this review article the authors Xiuling Li, Shunung Liang, Chee Hwee Tan, Shuwen Cao, Xiaoding Xu, Phei Er Saw and Wei Tao from Sun Yat-sen University, Guangzhou, China, Guangzhou University of Chinese Medicine, Guangzhou, China and Center for Harvard Medical School, Boston, MA, USA discuss the potential benefits of four plants endogenous to China and the enhancement of their therapeutic efficacy by nanotechnology intervention.
Plant derived natural products have been used for the treatment of various human diseases long before the intervention of modern medicine. The basis of modern medicine is still inspired by traditional medicine and therapies. However, ...
Scientists urge for investment now in highly potent vaccines to prevent the next pandemic
2021-02-09
LA JOLLA, CA--As new COVID-19 variants begin to throw vaccine efficacy in question, two leading scientists are calling for health agencies to invest in the development of vaccines that would be broadly effective against many different variants and strains of potential pandemic viruses.
In a END ...
Scientists create flexible biocompatible cilia that can be controlled by a magnet
2021-02-09
Researchers at the University of Campinas's Chemistry Institute (IQ-UNICAMP) in the state of São Paulo, Brazil, have developed a template-free technique to fabricate cilia of different sizes that mimic biological functions and have multiple applications, from directing fluids in microchannels to loading material into a cell, for example. The highly flexible cilia are based on polymer-coated iron oxide nanoparticles, and their motion can be controlled by a magnet.
In nature, cilia are microscopic hairlike structures found in large numbers on the surface of certain cells, causing currents ...
Can current smartphone technology tell you when a pandemic might come calling?
2021-02-09
Photoplethysmography (PPG) is a simple optical technique used to detect volumetric changes in peripheral blood circulation. It's used in smart watches, for example, to monitor pulse and heart rate, but PPG biosensors are also found in millions of smartphones, but without any current clinical applications.
In a study published online in the February 2021 issue of Chest, researchers at University of California San Diego School of Medicine, with industry collaborators, found that already embedded PPG in smartphones, in tandem with application software, could be used for remote clinical pulse oximetry to manage chronic cardiopulmonary disease and perhaps initial treatment and monitoring of persons affected in respiratory viral pandemics, such as COVID-19.
"Pulse oximetry monitoring ...
Design and deployment of COVID-19 technology responses and finding ways to make things
2021-02-09
As governments try to mitigate the spread of COVID-19, many are turning to contact tracing, including apps that track your location and electronic check-in QR codes. But with that technology come questions of personal safety, privacy, trust, control and collective action. So what can be done to improve these large-scale technological system roll-outs without infringing on a citizen's right to privacy?
"These systems are logging your physical social network," said Katina Michael, an Arizona State University professor at the School for the Future of Innovation in Society in the College of Global Futures and the School of Computing, Informatics and Decision Systems Engineering in the Ira A. Fulton Schools of Engineering. "The physical has become more ...
Shining a light on the true value of solar power
2021-02-09
Beyond the environmental benefits and lower electric bills, it turns out installing solar panels on your house actually benefits your whole community. Value estimations for grid-tied photovoltaic systems prove solar panels are beneficial for utility companies and consumers alike.
For years some utility companies have worried that solar panels drive up electric costs for people without panels. Joshua Pearce, Richard Witte Endowed Professor of Materials Science and Engineering and professor of electrical and computer engineering at Michigan Technological University, has shown the opposite is true -- grid-tied solar photovoltaic (PV) owners are actually subsidizing their non-PV ...
Super-Earth atmospheres probed at Sandia's Z machine
2021-02-09
ALBUQUERQUE, N.M. -- The huge forces generated by the Z machine at Sandia National Laboratories are being used to replicate the gravitational pressures on so-called "super-Earths" to determine which might maintain atmospheres that could support life.
Astronomers believe that super-Earths -- collections of rocks up to eight times larger than Earth -- exist in the millions in our galaxy. "The question before us is whether any of these super planets are actually Earthlike, with active geological processes, atmospheres and magnetic fields," said Sandia physicist Joshua Townsend.
The current ...
Low carbon transport at sea: Ferries voyage optimization in the Adriatic
2021-02-09
Energy efficiency or carbon intensity (defined as CO2 emissions per transport work, ed.) is a possible point of convergence between the International Maritime Organization (IMO) and EU regulations to cut GHG emissions and decarbonize shipping. Short term measures to increase energy efficiency and achieve carbon intensity savings include voyage optimization.
A new study led by the CMCC Foundation, realized in the framework of the Interreg Italy-Croatia END ...
Racism and anti-gay discrimination heighten risk for arrest and incarceration
2021-02-09
New research by Morgan Philbin, PhD, at Columbia University Mailman School of Public Health and colleagues looks at why Black young men who have sex with men (YMSM) are disproportionately subject to high rates of arrest and incarceration. They find that perceived racial discrimination, sexual orientation discrimination, and HIV-status discrimination are all associated with risk for criminal justice involvement in this population.
The research appears in the journal Stigma and Health.
Various studies have shown that Black men are imprisoned at nearly seven times the rate of white men; sexual minority young adults are nearly three times more likely to report being criminally sanctioned compared to their heterosexual ...
A study presents an algorithm that automates electrocardiogram recordings
2021-02-09
An electrocardiogram (ECG) is an examination that records the electrical activity of the heart during the cardiac cycle. It is non-invasive and usually involves placing electrodes on the subject's skin. It is a most indicated type of examination when there is suspected heart disease and also in routine preventive health check-ups.
The cardiac cycle entails the emptying of blood from the atria to the ventricles ("P" wave, red in the image), the contraction of the ventricles to propel blood to the different tissues and organs of the body ("QRS" wave, green in the image), and ...