Outcome predictive performance of admission chest radiographs in COVID-19 patients
2021 ARRS Virtual Annual Meeting research finds in the setting of high pretest probability of COVID-19 infection or with quick turnaround of rapid RT-PCR COVID-19 test, chest x-ray scoring can predict patient outcomes
2021-04-15
(Press-News.org) Leesburg, VA, April 15, 2021--A Scientific E-Poster to be presented at the 2021 ARRS Virtual Annual Meeting found that in the setting of a high pretest probability of COVID-19 infection or with a quick turnaround of the rapid real-time reverse transcriptase-polymerase chain reaction (RT-PCR) COVID-19 test, a chest x-ray (CXR) scoring system may be used prospectively to predict patient outcomes.
"We developed an accurate and reliable tool for classifying COVID-19 severity, which can be used both at the attending chest radiologist and junior resident level. This study identifies the laboratory, clinical and radiographic data that predict important patient outcomes such as death, intubation, and the need for chronic renal replacement therapy (CRRT)," wrote first author Russell Reeves of Thomas Jefferson University in Philadelphia, PA.
Reeves and colleagues identified patients with nucleic acid-confirmed COVID-19 admitted to an urban multicenter health system from March 16 to April 13, 2020. Three cardiothoracic radiologists and three diagnostic radiology residents then independently scored their admission CXRs, based on extent and severity of COVID-19 pneumonia. Demographic variables, clinical characteristics, and admission laboratory values were collected, while interrater reliability among attending, resident, and the combined group of graders was assessed.
Of the 240 patients (142 males, 98 females; median age, 65 years) who met the inclusion criteria, interrater reliability for CXR scoring was high (mean, 0.686) among the attending, residents, and combination of graders. Furthermore, there was no difference in outcomes across gender, race, ethnicity, or those with either a history of lung cancer or chronic obstructive pulmonary disease. Although CXR severity proved an independent predictor of death (p < 0.001), CXR severity was a non-independent predictor of CRRT (p = 0.007) and intubation (p < 0.001) but not extracorporeal membrane oxygenation.
"These findings are supported by prior work, validating the utility of CXR for patient prognostication, while adding new insight into COVID-19 infection during the initial presentation," the authors of this ARRS Annual Meeting E-Poster concluded.
INFORMATION:
Select press passes are still available for the ARRS 2021 All-Virtual Annual Meeting: https://www.arrs.org/AM21
Founded in 1900, the American Roentgen Ray Society (ARRS) is the first and oldest radiological society in North America, dedicated to the advancement of medicine through the profession of radiology and its allied sciences. An international forum for progress in medical imaging since the discovery of the x-ray, ARRS maintains its mission of improving health through a community committed to advancing knowledge and skills with an annual scientific meeting, monthly publication of the peer-reviewed American Journal of Roentgenology (AJR), quarterly issues of InPractice magazine, AJR Live Webinars and Podcasts, topical symposia, print and online educational materials, as well as awarding scholarships via The Roentgen Fund®.
[Attachments] See images for this press release:
ELSE PRESS RELEASES FROM THIS DATE:
2021-04-15
Scientists of Tomsk Polytechnic University has conducted research on the 35ClO2 isotope and developed a mathematical model and software, which allow predicting characteristics by 10 folds more accurate than already known results. The research work was conducted by a research team of Russian, German and Swiss scientists. The research findings are published in the Physical Chemistry Chemical Physics (IF: 3,4; Q1) academic journal and listed as one of the best articles.
The ClO2 molecule is extremely important for medicine and biophysics, as well as for the Earth atmosphere. It is used in medicine for disinfection and ...
2021-04-15
A study published this week in The Lancet Public Health examines how we can use our income assistance systems to address drug use and drug-related harm.
The study, led by University of British Columbia (UBC) medical sociologist Dr. Lindsey Richardson and conducted at the British Columbia Centre on Substance Use (BCCSU), tests whether varying the timing and frequency of income assistance payments can mitigate drug-related harms linked to the existing once-monthly payment schedule that is common across North America and Europe. Monthly synchronized income assistance payments have long been linked to considerable and costly increases in drug use and resulting harm, including overdose, hospital admission, treatment interruption and emergency service calls.
The study finds that varying when ...
2021-04-15
Tokyo, Japan - A team of scientists led by the Institute of Biomaterials and Bioengineering at Tokyo Medical and Dental University (TMDU) have created novel molecules that prevent human immunodeficiency virus (HIV) particles from attacking immune cells. This is accomplished by injecting compounds mimicking the protein the virus usually uses to enter the cells. This work may lead to new treatments for HIV that may be more effective at stopping the proliferation of the virus with fewer side effects.
HIV is a very dangerous pathogen because it attacks the very immune cells, including T helper cells, that are needed for the body to fight back. An HIV particle first ...
2021-04-15
Researchers from Kumamoto University (Japan) have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating pathological conditions like reduced kidney function, glomerular damage, inflammation and fibrosis. Metformin's mechanism is different from existing therapeutics which only treat symptoms, such as the blood pressure drug losartan, so the researchers believe that a combination of these medications at low dose will be highly beneficial.
CKD (chronic kidney disease) ...
2021-04-15
It is often said that before air travel our skies were bluer yet how, in the 21st century, could we ever know what light and colors were like one hundred years ago? Recently, a group of researchers from EPFL's Audiovisual Communications Laboratory, in the School of Computer and Communication Sciences (IC), had a unique opportunity to try to find out.
Normally hidden treasures locked away in the vaults of a handful of museums, the researchers were offered access to some of the original photographic plates and images of the scientist and inventor Gabriel Lippmann, who won the 1908 Nobel Prize in physics for his method of reproducing colors in photography.
In a paper just published in the Proceedings of the National ...
2021-04-15
Research led by the University of Kent's Durrell Institute of Conservation and Ecology (DICE) has found that the personification of animals in recent wildlife documentaries leads to significant misinformation and creates problems for public understanding of wider conservation.
In a research paper published by People and Nature, Professor Keith Somerville (DICE), Dr Amy Dickman, Dr Paul Johnson (both from the Wildlife Conservation Research Unit, University of Oxford), and Professor Adam Hart (University of Gloucestershire) argue that the portrayal of charismatic animals in nature films, while ...
2021-04-15
"This enables us to contrast the subjective perception of stress with an objective measurement method and compare the two," explains Nina Minkley. Contrary to expectations, it turned out that the effort invested in the task does not increase with its difficulty, nor does the stress level. The study was featured in the journal Frontiers in Education on 12. April 2021.
Simple questionnaire surveys criticised
To date, the stress experience of students has mostly been surveyed with questionnaires. But this approach has been criticised, because many factors have an effect on one's own perception that have nothing to do with the task. "For example, women often report higher stress levels ...
2021-04-15
Almost half a century ago the creators of Star Wars imagined a life-sustaining planet, Tatooine, orbiting a pair of stars. Now, 44 years later, scientists have found new evidence that that five known systems with multiple stars, Kepler-34, -35, -38, -64 and -413, are possible candidates for supporting life. A newly developed mathematical framework allowed researchers at New York University Abu Dhabi and the University of Washington to show that those systems -- between 2764 and 5933 light years from Earth, in the constellations Lyra and Cygnus -- support a permanent "Habitable Zone", a region around stars in which liquid water could ...
2021-04-15
Honey is humankind's oldest sweetener - and for thousands of years it was also the only one. Indirect clues about the significance of bees and bee products are provided by prehistoric petroglyphs on various continents, created between 8,000 and 40,000 years ago. Ancient Egyptian reliefs indicate the practice of beekeeping as early as 2600 year BCE. But for sub-Saharan Africa, direct archaeological evidence has been lacking until now. The analysis of the chemical residues of food in potsherds has fundamentally altered the picture. Archaeologists at Goethe University in cooperation with chemists at the University ...
2021-04-15
The advent and increased availability of 3D printing is leading to more customizable parts at lower costs across a spectrum of applications, from wearable smart devices to autonomous vehicles. Now, a research team based at Tohoku University has 3D printed the first proton exchange membrane, a critical component of batteries, electrochemical capacitors and fuel cells. The achievement also brings the possibility of custom solid-state energy devices closer to reality, according to the researchers.
The results were published on March 29 in ACS Applied Energy Materials, a journal of the American Chemical Society.
"Energy storage devices whose shapes can be tailored enable entirely new possibilities for applications related, for example, to smart wearable, electronic medical ...
LAST 30 PRESS RELEASES:
[Press-News.org] Outcome predictive performance of admission chest radiographs in COVID-19 patients
2021 ARRS Virtual Annual Meeting research finds in the setting of high pretest probability of COVID-19 infection or with quick turnaround of rapid RT-PCR COVID-19 test, chest x-ray scoring can predict patient outcomes
