National trends in pediatric deaths from fentanyl

JAMA Pediatrics

2023-05-08

(Press-News.org) About The Study: Mirroring trends seen among adults, pediatric deaths from fentanyl began to increase substantially in 2013, resulting in a more than 30-fold increase in mortality between 2013 and 2021. A surge that began in 2018 has led to a nearly 3-fold increase in deaths among older adolescents and a nearly 6-fold increase among children younger than 5 years. Across age groups, annual deaths peaked in 2020 and 2021, suggesting that the COVID-19 pandemic exacerbated this public health crisis.

Authors: Julie R. Gaither, Ph.D., M.P.H., R.N., of the Yale School of Medicine in New Haven, Connecticut, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamapediatrics.2023.0793)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2023.0793?guestAccessKey=c5601bcd-c204-4bbc-898f-98a0c8402abd&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050823

END

ELSE PRESS RELEASES FROM THIS DATE:

Ransomware attack associated with disruptions at adjacent emergency departments

2023-05-08

About The Study: This study found that hospitals adjacent to health care delivery organizations affected by ransomware attacks may see increases in patient census and may experience resource constraints affecting time-sensitive care for conditions such as acute stroke. These findings suggest that targeted hospital cyberattacks may be associated with disruptions of health care delivery at nontargeted hospitals within a community and should be considered a regional disaster. Authors: Christian Dameff, M.D., M.S., of the University of California, San Diego, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link ...

Air pollution from oil and gas production responsible for $77 billion in annual US health damages, contributes to thousands of early deaths, childhood asthma cases nationwide

2023-05-08

These health impacts affected communities in states with high oil and gas production, as well as states with limited or no gas activity, underlining the need for comprehensive regulatory action to protect Americans from the pollutants generated by this sector. Despite global efforts to transition from fossil fuels to clean energy, oil and gas (O&G) production is nearing record levels in the United States, posing concern among health experts about what this O&G growth means for air quality and human health. While ...

A sharp increase in the price of the gout drug colchicine led to lower use and poorer disease control, UCLA research suggests

2023-05-08

FINDINGS Due to a policy decision in 2010 by the U.S. Food and Drug Administration (FDA), the price of a prescription for the therapeutic gout drug colchicine increased nearly 16-fold from $11.25 in 2009 to $190.49 in 2011. Out-of-pocket costs for patients who took the drug jumped more than four-fold from $7.37 to $39.49 over the same period. Use of colchicine dropped 17% during this time and 27% over the following decade. Patients turned to alternative medications for gout such as allopurinol and corticosteroids. However, disease ...

An unprecedented view of gene regulation

2023-05-08

CAMBRIDGE, MA -- Much of the human genome is made of regulatory regions that control which genes are expressed at a given time within a cell. Those regulatory elements can be located near a target gene or up to 2 million base pairs away from the target. To enable those interactions, the genome loops itself in a 3D structure that brings distant regions close together. Using a new technique, MIT researchers have shown that they can map these interactions with 100 times higher resolution than has previously been possible. “Using this method, we generate the highest-resolution maps of the 3D genome that have ever been generated, and what we see are a lot of interactions between ...

AI helps create better, simpler hepatitis, COVID-19 tests

2023-05-08

Going beyond pregnancy and COVID-19, the world could someday soon come to rely on at-home tests for many diseases thanks in part to AI-fueled improvements. University of Florida scientists have used artificial intelligence tools to simplify a test that works for both hepatitis C and SARS-CoV-2, the virus that causes COVID-19. The simplified test happens in one small test tube in just a few minutes. With further refinement, it could come to doctor’s offices soon and, one day, even home tests that are as easy as a pregnancy test. “We are trying to build a home-based test that is as reliable as a lab-based test,” said Piyush ...

Leaky-wave metasurfaces: A perfect interface between free-space and integrated optical systems

2023-05-08

New York, NY—May 8, 2023—Researchers at Columbia Engineering have developed a new class of integrated photonic devices--“leaky-wave metasurfaces”--that can convert light initially confined in an optical waveguide to an arbitrary optical pattern in free space. These devices are the first to demonstrate simultaneous control of all four optical degrees of freedom, namely, amplitude, phase, polarization ellipticity, and polarization orientation--a world record. Because the devices are so thin, transparent, and compatible with photonic integrated circuits ...

AI predicts future pancreatic cancer

2023-05-08

An artificial intelligence tool has successfully identified people at the highest risk for pancreatic cancer up to three years before diagnosis using solely the patients’ medical records, according to new research led by investigators at Harvard Medical School and the University of Copenhagen, in collaboration with VA Boston Healthcare System, Dana-Farber Cancer Institute, and the Harvard T.H. Chan School of Public Health. The findings, published May 8 in Nature Medicine, suggest that AI-based population screening could be valuable in finding those at elevated risk for the disease and could expedite the diagnosis of a condition ...

Tiny microbes could brew big benefits for green biomanufacturing

2023-05-08

A research team led by Lawrence Berkeley National Laboratory (Berkeley Lab) and UC Berkeley has engineered bacteria to produce new-to-nature carbon products that could provide a powerful route to sustainable biochemicals. The advance – which was recently announced in the journal Nature – uses bacteria to combine natural enzymatic reactions with a new-to-nature reaction called the “carbene transfer reaction.” This work could also one day help reduce industrial emissions because it offers sustainable ...

Human Brain Project: Study presents large brain-like neural networks for AI

2023-05-08

In a new study in Nature Machine Intelligence*, researchers Bojian Yin and Sander Bohté from the HBP partner Dutch National Research Institute for Mathematics and Computer Science (CWI) demonstrate a significant step towards artificial intelligence that can be used in local devices like smartphones and in VR-like applications, while protecting privacy. They show how brain-like neurons combined with novel learning methods enable training fast and energy-efficient spiking neural networks on a large scale. Potential applications range from wearable AI to speech recognition and Augmented Reality. While modern artificial neural ...

Detailed image of the human retina

2023-05-08

What cell types are found in which human tissue, and where? Which genes are active in the individual cells, and which proteins are found there? Answers to these questions and more are to be provided by a specialised atlas – in particular how the different tissues form during embryonic development and what causes diseases. In creating this atlas, researchers aim to map not only tissue directly isolated from humans, but also structures called organoids. These are three-dimensional clumps of tissue that are cultivated in the laboratory and develop in a way similar ...

Consensus on the management of liver injury associated with targeted drugs and immune checkpoint inhibitors for hepatocellular carcinoma (version 2024)

National trends in pediatric deaths from fentanyl

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: