Intravenous Vitamin C for patients hospitalized with COVID-19

JAMA

2023-10-25

(Press-News.org) About The Study: In hospitalized patients with COVID-19, vitamin C had low probability of improving the primary composite outcome of organ support–free days and hospital survival in two harmonized randomized clinical trials.

Authors: Neill K. J. Adhikari, M.D.C.M., M.Sc., of the Sunnybrook Health Sciences Centre in Toronto, and Francois Lamontagne, M.D., M.Sc., of the Universite de Sherbrooke in Sherbrooke, Canada, are the corresponding authors.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2023.21407)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Media advisory: This study is being released to coincide with presentation at the European Society of Intensive Care Medicine Lives 2023 36th Annual Congress.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2023.21407?guestAccessKey=0ae1da3d-e149-40f9-84fc-0645baaf9e4a&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102523

END

ELSE PRESS RELEASES FROM THIS DATE:

Sigh ventilation in patients with trauma

2023-10-25

About The Study: In a randomized clinical trial including 524 trauma patients receiving mechanical ventilation with risk factors for developing acute respiratory distress syndrome, the addition of sigh breaths did not significantly increase ventilator-free days. Prespecified secondary outcome data suggest that sighs are well-tolerated and may improve clinical outcomes. Authors: Richard K. Albert, M.D., of the University of Colorado, Denver, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2023.21739) Editor’s Note: Please see the ...

Landiolol and organ failure in patients with septic shock

2023-10-25

About The Study: The results of this randomized clinical trial involving 126 patients do not support the use of the very short-acting beta-blocker landiolol for managing patients with tachycardia treated with norepinephrine for established septic shock. Authors: Tony Whitehouse, M.D., of Queen Elizabeth Hospital in Birmingham, United Kingdom, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2023.20134) Editor’s Note: Please ...

Convalescent plasma reduces mortality by 10% in COVID-19 patients in acute respiratory distress and on artificial respiratory assistance

2023-10-25

This is the conclusion of a multicentre study conducted by the University Hospital of Liège (CHU of Liège) in collaboration with 17 hospital intensive care departments in Belgium during the Covid-19 phases between October 2020 and March 2022. This is the first study to look specifically at the effect of administering convalescent plasma to these patients whose vital prognosis is severely compromised. It confirms the value of this method for inducing passive immunisation in these patients. The results are published in the leading medical journal The New England Journal of Medicine. In a study published in The New ...

The changing face of gun ownership in the United States

2023-10-25

Learning how to shoot a handgun at a Las Vegas gun convention had never been on Jennifer Hubbert’s bucket list. But last fall, the professor of anthropology and Asian studies found herself doing just that. “Given my research, it felt like something I needed to do,” she says. Hubbert is currently exploring a novel question regarding gun culture in the United States: “What does it mean to be a liberal gun owner?” The National Endowment for the Humanities (NEH) has recently awarded Hubbert with a grant to support her research and book project: Gun Culture 4.0: Understanding the New Demographics of ...

Dr. Anthony Fauci to be awarded 2024 Inamori Ethics Prize by Inamori International Center for Ethics and Excellence

2023-10-25

CLEVELAND, OH—The Inamori International Center for Ethics and Excellence at Case Western Reserve University will award Dr. Anthony Fauci, a physician, immunologist, and infectious disease expert, with the 2024 Inamori Ethics Prize. “Dr. Fauci has cared not only for the nation’s health, but also the health of the world,” said Case Western Reserve President Eric W. Kaler. “As a scientist, research leader and public health advisor, his contributions to scientific discovery have truly improved lives. His leadership through one of the most challenging times in history—the COVID-19 pandemic—serves ...

New study: Pig welfare outweighs climate concerns for consumers

2023-10-25

Pork production is a societal concern on several fronts: antibiotics use, infectious disease, poor animal welfare and climate and environmental pressures. Even though the beef, coffee and chocolate industries are each major climate culprits, the world's total consumption of pork emits hundreds of millions of tons of CO2 every year. But are you willing to fork over extra cash for a more climate-friendly pork roast? Or, are there other considerations that would increase your willingness to pay more? And if so, how much of a premium would you be willing to pay? Researchers from the University of Copenhagen’s Department of Food and Resource Economics investigated ...

Researchers induce brain activation using infrared light-controlled drugs

2023-10-25

Studying the brain remains one of the most challenging endeavors in neuroscience. Researchers have explored various methods for live imaging and stimulation of deep brain activity. One such method is multiphoton excitation using pulsed infrared (IR) light. This type of light is weakly absorbed by tissues and can penetrate through the bone and deep into organs like the brain. However, it has its limitations to produce focused images and to control cellular activity with precision. To overcome this, scientists have been exploring three-photon excitation with ultrafast pulsed IR light, to achieve ...

People with severe mental illness at 50 per cent higher risk of death following COVID-19 infection

2023-10-25

New research from King’s College London has found that in the UK people with severe mental illness were at increased risk of death from all causes following COVID-19 infection compared to those without severe mental illness. Published in the British Journal of Psychiatry, the study investigated the extent to which having severe mental illness, which includes schizophrenia and psychosis, increased the risk of death during the first two waves of the COVID-19 pandemic. Researchers at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) and ESRC Centre for Society and Mental Health analysed data from over 660,000 ...

Closing digital skills gap could spur global economic growth by $11.5 trillion

2023-10-25

This significant lack of expertise means firms are not fully embracing the automation revolution, costing businesses valuable time and money. Intelligent Automation: Bridging the Gap between Business and Academia delves into how companies and universities can use intelligent automation to address the challenges preventing the workforce from prospering amid the Fourth Industrial Revolution. (NEW YORK – October 16, 2023) The economic benefits of intelligent automation are vast, potentially totaling trillions of dollars in economic growth, according to research in a new book. Businesses and organizations ...

Our favorite bittersweet symphonies may help us deal better with physical pain

2023-10-25

Research has shown that music might be a drug-free way to lower humans’ pain perception. This decreased sensitivity to pain – also known as hypoalgesia – can occur when pain stimuli are disrupted between their point of input and where they are recognized as pain by the conscious mind. In a new study, researchers in Canada have examined what type of music helps to dampen pain perception. “In our study, we show that favorite music chosen by study participants has a much larger effect on acute thermal pain reduction than unfamiliar relaxing music” said Darius Valevicius, a doctoral student at the Université ...

LAST 30 PRESS RELEASES:

How rice plants tell head from toe during early growth

Scientists design solar-responsive biochar that accelerates environmental cleanup

Construction of a localized immune niche via supramolecular hydrogel vaccine to elicit durable and enhanced immunity against infectious diseases

Deep learning-based discovery of tetrahydrocarbazoles as broad-spectrum antitumor agents and click-activated strategy for targeted cancer therapy

DHL-11, a novel prieurianin-type limonoid isolated from Munronia henryi, targeting IMPDH2 to inhibit triple-negative breast cancer

Discovery of SARS-CoV-2 PLpro inhibitors and RIPK1 inhibitors with synergistic antiviral efficacy in a mouse COVID-19 model

Neg-entropy is the true drug target for chronic diseases

Oxygen-boosted dual-section microneedle patch for enhanced drug penetration and improved photodynamic and anti-inflammatory therapy in psoriasis

Around the world, children’s cooperative behaviors and norms converge toward community-specific norms in middle childhood, Boston College researchers report