PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Mirvie announces completion of enrollment of 10,000 person landmark research study for pregnancy health

Study with leading physician-scientists will provide unprecedented insights into the underlying biology of pregnancy to identify those most at risk for adverse pregnancy complications that affect 1 in 5 pregnancies

2023-11-14
(Press-News.org) South San Francisco, CA (November 14, 2023) – Mirvie, a company pioneering the prediction of life-threatening pregnancy complications months in advance, today announced the completion of enrollment of its landmark 10,000 person research study for pregnancy health, in collaboration with leading experts in obstetrics and maternal-fetal medicine.

“This monumental effort represents a new chapter for pregnancy health,” said Maneesh Jain, CEO and co-founder of Mirvie. “Today, we face a massive crisis in maternal health, and innovative solutions are desperately needed. The audacious scale of this generalizable study – involving over 10,000 individuals – creates the largest and richest biobank of pregnancy transcriptomes ever to exist.”

Led by internationally renowned experts in pregnancy health, the U.S.-based study seeks to understand how RNA messages found in expectant mothers’ blood can predict life-threatening pregnancy complications. One area of study relates to cell-free RNA’s prediction of preeclampsia months in advance, a leading cause of pregnancy-related morbidity and mortality which impacts an estimated 1 in 12 pregnancies in the U.S. Mirvie has included numerous study sites across the country, prioritizing geographically and racially diverse enrollment to ensure that this study represents the communities at greatest risk for adverse pregnancy outcomes. In addition to academic sites, the study includes community hospitals and direct-to-participant enrollment across 1,222 unique zip codes throughout the U.S.

“The geographical and racial diversity represented in our study is one of its greatest strengths,” said Dr. Joseph Biggio, maternal-fetal medicine specialist, system chair and service line leader of Women’s Services of Ochsner Health in Louisiana, and principal investigator of the study at Ochsner Health in Louisiana. “With pregnancy complications disproportionately affecting communities of color, we are committed to increasing inclusion in research for individuals who have historically been underrepresented and underserved.”

Dr. Cynthia Gyamfi-Bannerman, maternal-fetal medicine specialist at UC San Diego Health and professor and chair of the Department of Obstetrics, Gynecology, and Reproductive Sciences at University of California San Diego School of Medicine added, “This study will offer a vast data set in pregnancy health – including comprehensive clinical information and paired biospecimens – that may change the way we identify those at risk, and ultimately, how we improve care for adverse pregnancy complications.”

To learn more about the study, please visit https://clinicaltrials.gov/study/NCT06074601?cond=Preeclampsia&term=Mirvie,%20Miracle%20of%20Life&rank=1.

Mirvie is continuing a similar study in sub-Saharan Africa with support from the Bill and Melinda Gates Foundation, who awarded the company a $4.6 million grant earlier this year.

About The Mirvie RNA Platform

The proprietary Mirvie RNA platform combines revolutionary analysis of tens of thousands of RNA messages from the baby, the placenta and the mom, with machine learning. The platform opens a new window into pregnancy health for expecting parents to act and their doctors to intervene before unexpected complications become a crisis. It enables proactive, personalized and preventive pregnancy care for the well-being of expecting parents and babies. Mirvie is conducting ongoing clinical research to validate existing peer-reviewed evidence, to enhance the Mirvie RNA platform performance, and to improve the understanding of other pregnancy complications.

About Mirvie

‍Mirvie is shaping the future of pregnancy health by providing women, expecting parents and their doctors with an early detection window to intervene before unexpected pregnancy complications become a crisis. One in five pregnancies is impacted by complications that lead to lifelong health consequences for expecting parents and babies. The proprietary Mirvie RNA platform uses a simple blood test to reveal vital information about a pregnancy’s unique biology and detect complications months before they occur. The idea for Mirvie was sparked by the personal experience of one of the founders whose daughter was born prematurely. Mirvie’s team of world-class scientists and entrepreneurs have brought to market category-first, non-invasive tests in both women’s health and in early cancer detection, used by millions today. Founded in 2018, Mirvie has raised more than $90 million in early-stage financing from top-tier investors, including Decheng Capital, Foresite Capital, General Catalyst, GV, Khosla Ventures, and Mayfield. Mirvie is based in South San Francisco, California. To learn more about Mirvie, please visit www.mirvie.com.

 

 

END


ELSE PRESS RELEASES FROM THIS DATE:

Study finds strongest evidence yet for local sources of cosmic ray electrons

Study finds strongest evidence yet for local sources of cosmic ray electrons
2023-11-14
A new study using data from the CALorimetric Electron Telescope (CALET) instrument on the International Space Station has found evidence for nearby, young sources of cosmic ray electrons, contributing to a greater understanding of how the galaxy functions as a whole.  The study included more than seven million data points representing particles arriving at CALET’s detector since 2015, and CALET’s ability to detect electrons at the highest energies is unique. As a result, the data includes more electrons at high energies than any previous work. That makes the statistical analysis of the data more robust and lends support to the conclusion that there are one or more local ...

Special Issue of Criminology & Public Policy examines cybercrime and cybersecurity

2023-11-14
Cybercrime—computer hacking, social engineering, intellectual property theft, electronic fraud, online interpersonal violence, identity theft, and Internet-facilitated sexual victimization—is a leading threat to national security, with millions of victims in both the United States and around the world, and billions of dollars being spent to combat it. Criminology and related disciplines are just beginning to understand cybercrime and how best to deter and prevent it—or at least reduce its harms. ...

Special issue of Medicare Care supports the need to study economic impacts on patient outcomes

2023-11-14
November 14, 2023 — A special supplemental issue of Medical Care, sponsored by the Assistant Secretary for Planning and Evaluation (ASPE) in the U.S. Department of Health and Human Services, supports the growing recognition that economic factors often affect health outcomes, patient decision-making, and equity in health care. Medical Care, the official journal of the Medical Care Section of the American Public Health Association, is published in the Lippincott portfolio by Wolters Kluwer.  The scope of patient-centered outcomes research (PCOR) was expanded to include economic outcomes in the 2019 reauthorization ...

Alcohol consumption and epigenetic age acceleration across human adulthood

Alcohol consumption and epigenetic age acceleration across human adulthood
2023-11-14
“Our findings may help to understand the role of alcohol-associated biological aging in the development of age-related diseases such as CVD and cancer.” BUFFALO, NY- November 14, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, “Alcohol consumption and epigenetic age acceleration across human adulthood.” The alcohol-associated biological aging remains to be studied across adulthood. In their new study, ...

How one lab at MSK is working to harness the power of the immune system against cancer

How one lab at MSK is working to harness the power of the immune system against cancer
2023-11-14
Investigator Ming Li, PhD, has dedicated his career to understanding the intricate workings of the immune system — both in general and for the critical role it plays in cancer. Study by study, his lab at Memorial Sloan Kettering Cancer Center (MSK) is sharing new insights into the molecular and cellular mechanisms involved in immune regulation — a type of knowledge-building that scientists call “basic science” or “discovery science.” But Dr. Li is equally focused ...

University of Kentucky researcher helps solve 60-year mystery inside heart, publishes in Nature

University of Kentucky researcher helps solve 60-year mystery inside heart, publishes in Nature
2023-11-14
LEXINGTON, Ky. (Nov. 14, 2023) — One University of Kentucky researcher has helped solve a 60-year-old mystery about one of the body’s most vital organs: The heart. Kenneth S. Campbell, Ph.D., the director of translational research in the Division of Cardiovascular Medicine in the UK College of Medicine, helped map out an important part of the heart on a molecular level. The study titled “Cryo-EM structure of the human cardiac myosin filament” was published online in the prestigious journal Nature earlier this month. The heart is made up of billions of cells. Each cell contains thousands ...

Melting ice falling snow: Sea ice declines enhance snowfall over West Antarctica

2023-11-14
UNIVERSITY PARK, Pa. — As the world continues to warm, Antarctica is losing ice at an increasing pace, but the loss of sea ice may lead to more snowfall over the ice sheets, partially offsetting contributions to sea level rise, according to Penn State scientists. The researchers analyzed the impacts of decreased sea ice in the Amundsen Sea in West Antarctica and found the ice-free ocean surface leads to more moisture in the atmosphere and heavier snowfalls on the ice sheet, the team reported in the journal Geophysical Research Letters. While the additional snowfall is not enough to offset the impacts of melting ice, including it in climate ...

Dangerous bee virus less deadly in at least one US forest, researchers find

2023-11-14
UNIVERSITY PARK, Pa. — This year’s cold and flu season is bringing good news for honey bees: Penn State researchers have found that the deadly deformed wing virus (DMV) may have evolved to be less deadly in at least one U.S. forest. The findings could have implications for preventing or treating the virus in managed colonies, researchers said. The study, which was recently published in the Proceedings of the Royal Society B, compared rates and severity of DWV in wild honey bees from ...

Using machine learning, existing fiber optic cables to track Pittsburgh hazards

2023-11-14
UNIVERSITY PARK, Pa. — Existing fiber optic cables used for high-speed internet and telecommunications, in combination with machine learning, may be able to help scientists track ground hazards in Pittsburgh. The National Science Foundation awarded a $937,000 grant to a team of Penn State and Carnegie Mellon University (CMU) researchers to further develop the low-cost monitoring approach. The effort, which is led by Tieyuan Zhu, associate professor of geosciences at Penn State, relies on prior research that shows hazards such as flooding, landslides, sinkholes and leaking pipes can be monitored at a fraction of the cost of existing methods. The distributed acoustic sensing ...

Downloading NASA’s dark matter data from above the clouds

Downloading NASA’s dark matter data from above the clouds
2023-11-14
Data from a NASA mission to map dark matter around galaxy clusters has been saved by a new recovery system designed by scientists at the University of Sydney. The system allowed the retrieval of gigabytes of information, even after communication failed and the balloon-based telescope was damaged in the landing process. In April, the Super Pressure Balloon Imaging Telescope (SuperBIT) was launched from Wānaka Airport, New Zealand, suspended under a helium-filled balloon the size of a sports stadium on top of the Earth’s ...

LAST 30 PRESS RELEASES:

Unlocking the mysteries of the human gut

High-quality nanodiamonds for bioimaging and quantum sensing applications

New clinical practice guideline on the process for diagnosing Alzheimer’s disease or a related form of cognitive impairment or dementia

Evolution of fast-growing fish-eating herring in the Baltic Sea

Cryptographic protocol enables secure data sharing in the floating wind energy sector

Can drinking coffee or tea help prevent head and neck cancer?

Development of a global innovative drug in eye drop form for treating dry age-related macular degeneration

Scientists unlock secrets behind flowering of the king of fruits

Texas A&M researchers illuminate the mysteries of icy ocean worlds

Prosthetic material could help reduce infections from intravenous catheters

Can the heart heal itself? New study says it can

Microscopic discovery in cancer cells could have a big impact

Rice researchers take ‘significant leap forward’ with quantum simulation of molecular electron transfer

Breakthrough new material brings affordable, sustainable future within grasp

How everyday activities inside your home can generate energy

Inequality weakens local governance and public satisfaction, study finds

Uncovering key molecular factors behind malaria’s deadliest strain

UC Davis researchers help decode the cause of aggressive breast cancer in women of color

Researchers discovered replication hubs for human norovirus

SNU researchers develop the world’s most sensitive flexible strain sensor

Tiny, wireless antennas use light to monitor cellular communication

Neutrality has played a pivotal, but under-examined, role in international relations, new research shows

Study reveals right whales live 130 years — or more

Researchers reveal how human eyelashes promote water drainage

Pollinators most vulnerable to rising global temperatures are flies, study shows

DFG to fund eight new research units

Modern AI systems have achieved Turing's vision, but not exactly how he hoped

Quantum walk computing unlocks new potential in quantum science and technology

Construction materials and household items are a part of a long-term carbon sink called the “technosphere”

First demonstration of quantum teleportation over busy Internet cables

[Press-News.org] Mirvie announces completion of enrollment of 10,000 person landmark research study for pregnancy health
Study with leading physician-scientists will provide unprecedented insights into the underlying biology of pregnancy to identify those most at risk for adverse pregnancy complications that affect 1 in 5 pregnancies