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Can taking antibiotics combat the gut bacteria that contribute to the pathogenesis of COVID-19?

2024-03-20
(Press-News.org) New research indicates that antibiotics can effectively target bacteria in the gut that harbor the virus that causes COVID-19 and produce toxin-like peptides that contribute to COVID-19-related symptoms. In the study, which involved 211 participants and was published in the Journal of Medical Virology, individuals who received early antibiotic treatment after having COVID-19 recovered more quickly than those who did not receive antibiotics.

The authors had already evaluated the efficacy of certain antibiotics in SARS-CoV-2-infected bacterial cultures in vitro, and this new study demonstrates promising results with the use of the combination of 2 antibiotics (amoxicillin and rifaximin) within the first 3 days.

Furthermore, a significant number of patients who received antibiotics within the first 3 days and for a duration of 7 days during the acute phase of COVID-19 did not develop long COVID.

"Our findings suggest that antibiotics should be considered in acute infection and Long COVID. The study also lays the foundation for additional vaccine strategies," said co–corresponding author Marina Piscopo, PhD, of the University of Naples Federico, in Italy.

URL upon publication: https://onlinelibrary.wiley.com/doi/10.1002/jmv.29507

 

Additional Information
NOTE: The information contained in this release is protected by copyright. Please include journal attribution in all coverage. For more information or to obtain a PDF of any study, please contact: Sara Henning-Stout, newsroom@wiley.com.

About the Journal
Journal of Medical Virology is a clinical virology journal publishing original scientific papers on fundamental and applied research concerning viruses affecting humans. We welcome reports describing the characterization, diagnosis, epidemiology, immunology and pathogenesis of human viral infections and diseases. Basic studies on virus morphology, genetics, replication and host-cell interactions are also accepted.

About Wiley
Wiley is a knowledge company and a global leader in research, publishing, and knowledge solutions. Dedicated to the creation and application of knowledge, Wiley serves the world’s researchers, learners, innovators, and leaders, helping them achieve their goals and solve the world's most important challenges. For more than two centuries, Wiley has been delivering on its timeless mission to unlock human potential. Visit us at Wiley.com. Follow us on Facebook, Twitter, LinkedIn and Instagram.

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[Press-News.org] Can taking antibiotics combat the gut bacteria that contribute to the pathogenesis of COVID-19?