Smoking cessation after initial treatment failure with varenicline or nicotine replacement

JAMA

2024-05-02

(Press-News.org) About The Study: For individuals who smoked but did not achieve abstinence after treatment with varenicline, increasing the dosage enhanced abstinence versus continuing, whereas for nonabstainers initially treated with combined nicotine replacement therapy, a dosage increase or switch to varenicline enhanced abstinence and may be viable rescue strategies.

Authors: Paul M. Cinciripini, Ph.D., of the University of Texas MD Anderson Cancer Center in Houston, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2024.4183)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.4183?guestAccessKey=214ecd8c-5bb9-4da2-93b8-7c1512337be9&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050224

END

ELSE PRESS RELEASES FROM THIS DATE:

How the brain’s arousal center helps control visual attention too

2024-05-02

The locus coeruleus (LC) is a small region of the brainstem that produces norepinephrine, a chemical with powerful effects on arousal and wakefulness which plays an important role in the body’s response to stress or panic. Now, research from the University of Chicago shows it plays a specific role in visual sensory processing as well. In a new study published in Neuron, neuroscientists artificially increased neuronal activity in the LC by briefly shining light on genetically modified neurons. They saw that this manipulation selectively enhanced performance in non-human primates performing a visual attention task, underscoring the crucial role that attention plays in sensory ...

Increasing doses of varenicline or nicotine replacement helps persistent smokers quit

2024-05-02

HOUSTON ― For most smokers, quitting on the first attempt is likely to be unsuccessful, but a new study from The University of Texas MD Anderson Cancer Center found patients were more likely to quit if their cessation regimen was altered and doses were increased. Researchers also found that varenicline, a cessation medication, was more effective than combined nicotine replacement therapy (CNRT), such as patches or lozenges. The study, published today in JAMA, revealed smokers who failed to quit with varenicline in the trial’s first phase were seven times more likely to quit by the end of the second phase if varenicline ...

Artificial intelligence yields promising results for advancing coronary angiography

2024-05-02

Long Beach, Calif. – May 2, 2024 – New insights from the AI-ENCODE study showed artificial intelligence (AI) successfully allowed the automated extraction of key functional and physiological data from routine angiograms. The late-breaking results were presented today at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions. Coronary angiography is a widely used diagnostic procedure for identifying coronary artery disease (CAD), performed in over one million patients annually in the United States. Currently, data extracted from coronary angiograms are confined to detecting blockages in the coronary arteries. However, AI technology ...

Non-fasting pre-procedural strategy for cardiac catheterization significantly improved patient well-being and satisfaction

2024-05-02

Long Beach, Calif. – May 2, 2024 – New data from the CALORI Cardiac Catheterization trial shows significant improvement in patient well-being and satisfaction without compromising safety after implementation of a liberal non-fasting strategy prior to a cardiac catheterization procedures. The late-breaking results were presented today at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions. More than one million cardiac catheterizations are performed each year in the U.S. to diagnose heart problems. The risk of complications ...

Gene therapy treatment increasing body’s signal for new blood vessel growth shows promise

2024-05-02

Long Beach, Calif. – May 2, 2024 – Final 12-month data from the EXACT trial demonstrates safety and efficacy results for a vascular endothelial growth factor (VEGF) gene therapy treatment for patients who have advanced coronary artery disease (CAD). The late-breaking results were presented today at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions. CAD, also known as coronary heart disease or ischemic heart disease, affects about 20.5 million U.S. adults – making it the most common type of heart disease in the ...

Novel score system accurately identifies lesions reducing risk of PCI complications

2024-05-02

Long Beach, Calif. – May 2, 2024 – New data demonstrated that a left main (LM) bifurcation-specific novel scoring system (LM V-RESOLVE), based on three simple baseline angiographic findings, could help to rapidly discriminate lesions at risk of side branch (SB) occlusion during LM bifurcation percutaneous coronary intervention (PCI) – reducing risk during the procedure. The results from the prospective trial were presented today as late-breaking science at the Society for Cardiovascular Angiography & Interventions (SCAI) ...

Women need better treatments for bacterial vaginosis

2024-05-02

BALTIMORE, May 2, 2024: Bacterial Vaginosis (BV) affects about one-quarter of reproductive-age women and is linked to adverse health outcomes, such as increased HIV risk. Yet for decades, BV treatment in the United States has largely relied on antibiotics, and BV recurrence is common following antibiotic therapy. Now, two European clinical trials have shown limited success with a different type of medication used to treat BV called dequalinium chloride (DQC). DQC—an antiseptic—has been in use for several decades in countries throughout Europe as an alternative treatment for BV. It is not currently approved by the U.S. ...

Webb telescope probably didn’t find life on an exoplanet — yet

2024-05-02

Recent reports of NASA’s James Webb Space Telescope finding signs of life on a distant planet understandably sparked excitement. A new study challenges this finding, but also outlines how the telescope might verify the presence of the life-produced gas. The UC Riverside study, published in the Astrophysical Journal Letters, may be a disappointment to extraterrestrial enthusiasts but does not rule out the near-future possibility of discovery. In 2023 there were tantalizing reports of a biosignature gas in the atmosphere of planet K2-18b, ...

Radial arterial access found superior to femoral access in percutaneous coronary intervention

2024-05-02

Long Beach, Calif. – May 2, 2024 – New data demonstrate the superiority of radial arterial access compared to femoral arterial access for coronary interventions. Findings showed radial access was associated with lower rates of in-hospital mortality, major access bleeding, and other major vascular complications compared with femoral access. The late-breaking results were presented today at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions. Historically, femoral arterial access, through the groin, for percutaneous coronary intervention (PCI) was the standard. Radial access, or ...

Money on their minds: Health-related costs top older adults’ concerns for people their age, poll finds

2024-05-02

From medical and dental care to medications, insurance and nursing homes, health-related costs weigh heavily on the minds of older Americans of all backgrounds, a new poll suggests. Asked to rate their level of concern about 26 different health-related topics for people over 50 in their community, five of the six issues that the most people cited as very concerning involved health costs. The sixth – financial scams and fraud – also had to do with money. Those same six topics rose to the top no matter what ...

Smoking cessation after initial treatment failure with varenicline or nicotine replacement

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: