Recovery potential in patients after cardiac arrest who die after limitations or withdrawal of life support.

JAMA Network Open

2025-03-25

(Press-News.org) About The Study: In this cohort study of comatose patients resuscitated from cardiac arrest, most who died after withdrawal of life-sustaining therapy were considered by experts to have had recovery potential. These findings suggest that novel solutions to avoiding deaths based on biased prognostication or incomplete information are needed.

Corresponding Author: To contact the corresponding author, Jonathan Elmer, MD, MS, email elmerjp@upmc.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.1714)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.1714?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=032525

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

LGBTQ+ inclusive policies, nurse job outcomes, and quality of care in hospitals.

2025-03-25

About The Study: Nurses in hospitals with high lesbian, gay, bisexual, transgender, queer or questioning, and other sexual and gender minority (LGBTQ+) inclusion reported more favorable job outcomes and care quality in this cross-sectional study. Hospitals should understand that implementing LGBTQ+ inclusive policies goes beyond compliance or diversity; it is essential for improving the work climate, enhancing staff well-being, and optimizing care delivery. Corresponding Author: To contact the corresponding author, Hyunmin Yu, PhD, email hyuy@nursing.upenn.edu. To access the embargoed study: Visit our For The Media ...

C. diff uses toxic compound to fuel growth advantage

2025-03-25

The pathogen C. diff — the most common cause of health care-associated infectious diarrhea — can use a compound that kills the human gut’s resident microbes to survive and grow, giving it a competitive advantage in the infected gut. A team led by investigators at Vanderbilt University Medical Center has discovered how C. diff (Clostridioides difficile) converts the poisonous compound 4-thiouracil, which could come from foods like broccoli, into a usable nutrient. Their findings, published March 25 in the journal Cell Host & Microbe, increase ...

Nation of Lifesavers™ takes CPR education to Japan

2025-03-25

DALLAS, March 25, 2025 — Understanding how to properly respond in a cardiac emergency when seconds matter is critical to everyone, everywhere. That is why the American Heart Association, devoted to changing the future to a world of healthier lives for all, and its Nation of Lifesavers™ national ambassador and Buffalo Bills safety, Damar Hamlin, are expanding the Chasing M’s Foundation cardiopulmonary resuscitation (CPR) tour to Tokyo during March 27-30. This work is supporting the American Heart Association’s impact goal to improve survival rates of out-of-hospital cardiac arrest[1]. “Our national Nation ...

ACS study finds nearly four million pre-mature lung cancer deaths in U.S. averted and 76 million years of lives gained due to tobacco control

2025-03-25

New research led by American Cancer Society (ACS) researchers estimates more than 3.8 million lung cancer deaths were averted and a little over 76 million years of life gained in the United States during 1970-2022 due to substantial reductions in smoking prevalence driven by tobacco control. The study is published today in CA: A Cancer Journal for Clinicians. “The substantial estimated numbers of averted lung cancer deaths and person-years of life gained highlight the remarkable effect of progress ...

PCSK9 and APOA4: the dynamic duo in TMAO-induced cholesterol metabolism and cholelithiasis

2025-03-25

Background and Aims Cholesterol synthesis and gallstone formation are promoted by trimethylamine-N-oxide (TMAO), a derivative of trimethylamine, which is a metabolite of gut microbiota. However, the underlying mechanisms of TMAO-induced lithogenesis remain incompletely understood. This study aimed to explore the specific molecular mechanisms through which TMAO promotes gallstone formation. Methods Enzyme-linked immunosorbent assays were used to compare serum concentrations of TMAO, apolipoprotein A4 (APOA4), and ...

Gas injection setup in new fusion system is guided by public-private research

2025-03-25

When the plasma inside a fusion system starts to misbehave, it needs to be quickly cooled to prevent damage to the device. Researchers at Commonwealth Fusion Systems believe the best bet is a massive gas injection: essentially, a well-timed, rapid blast of cooling gas inside their fusion system, which is known as SPARC. But how many gas valves does it take to quickly tame a plasma that is hotter than the sun? The team has to strike the perfect balance: with too few valves, some parts of SPARC might overheat. With too many, valuable space inside the ...

Offering paid time off dramatically cuts odds of employees quitting their jobs

2025-03-25

About 4.5 million workers in the United States quit their jobs in 2022, continuing a trend that began after the 2007 Great Recession. Despite better labor conditions and the pandemic’s decline, many adults are still less willing to return to work compared to previous recessions, making it harder for companies to attract and retain top talent. Moreover, voluntary turnover – when an employee quits their job as opposed to being fired or laid off – costs U.S. businesses more than $1 trillion each year. Beyond recruitment and training expenses, turnover disrupts operations, damages customer relationships, and often leads to further departures. Replacing an employee ...

City of Hope opens phase 1 clinical trial aiming to one day transform rectal cancer into a disease treatable with radiation therapy to avoid potential long-term side effects of surgery

2025-03-25

LOS ANGELES — City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, has opened a phase 1 trial seeking to one day transform rectal cancer from a mostly radiation-resistant disease to one that can be cured using radiation and chemotherapy. “Many cancers are cured through radiation therapy alone or radiation in combination with chemotherapy, including — but not limited to — prostate, head and ...

Maternal deaths from cardiovascular causes on the rise in U.S.

2025-03-25

The rate of maternal mortality related to cardiovascular causes more than doubled between 1999 and 2022 in the United States, according to a study being presented at the American College of Cardiology’s Annual Scientific Session (ACC.25). The finding is concerning, especially as the U.S. has the highest overall rate of maternal mortality among all developed countries, researchers said. Since cardiovascular problems are a leading cause of death around the time of pregnancy and childbirth, the new findings shed light on the drivers behind recent trends and draw attention to particularly high rates of mortality seen among ...

New evidence links microplastics with chronic disease

2025-03-25

Tiny fragments of plastic have become ubiquitous in our environment and our bodies. Higher exposure to these microplastics, which can be inadvertently consumed or inhaled, is associated with a heightened prevalence of chronic noncommunicable diseases, according to new research being presented at the American College of Cardiology’s Annual Scientific Session (ACC.25). Researchers said the new findings add to a small but growing body of evidence that microplastic pollution represents an emerging health threat. In terms of its relationship with stroke risk, for example, microplastics concentration ...

National Foundation for Cancer Research CEO Sujuan Ba Named One of OncoDaily’s 100 Most Influential Oncology CEOs of 2025

Caring Cross and Boston Children’s Hospital collaborate to expand access to gene therapy for sickle cell disease and beta thalassemia

Mount Sinai review maps the path forward for cancer vaccines, highlighting promise of personalized and combination approaches

Illinois study: How a potential antibiotics ban could affect apple growers

UC Irvine and Jefferson Health researchers find differences between two causes of heart valve narrowing

[Press-News.org] Recovery potential in patients after cardiac arrest who die after limitations or withdrawal of life support.
JAMA Network Open

Recovery potential in patients after cardiac arrest who die after limitations or withdrawal of life support.

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: