Parental diseases of despair and suicidal events in their children

JAMA Network Open

2025-09-12

(Press-News.org) About The Study: This cohort study found an association of parental diseases of despair (defined as a suicide attempt, alcohol-related disease, or substance use disorder) with youth suicidal events; this finding may be underlying the increase in adolescent suicidal behavior observed in the U.S. over the past 2 decades. Improved access to care for parents with diseases of despair and systematic screening and referral of their offspring could help to reduce the adolescent suicide rate.

Corresponding Author: To contact the corresponding author, David A. Brent, MD, email brentda@upmc.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.31442)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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Parental diseases of despair and suicidal events in their children

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