Indian adolescents are mostly starting their periods at an earlier age than 25 years ago

Temporary medical centers in Gaza known as "Medical Points" (MPs) treat an average of 117 people daily with only about 7 staff per MP, filling a critical role despite severe staffing and supply shortages (with insulin and cancer treatments unavailable in over 90% of cases, for instance).   Article URL: https://plos.io/4nn4PRX Article Title: Resilience amid chaos: The role of Gaza medical points Author Countries: Jordan, Palestine, United States Funding: The author(s) received no specific funding for this work. END ...

In an analysis by race, sex, age, and geography, alcohol-induced death rates in 2024 are nearly double those in 1999, with a sharp increase at the onset of the COVID-19 pandemic. Although rates are higher for men, the largest increase in alcohol-induced deaths over the full 25-year period occurred in females aged 25-34, according to a study published on September 17 by Dr. Tony Wong and colleagues at UCLA in the open-access journal PLOS Global Public Health. Alcohol-induced deaths have been increasing over the past two decades. Particularly concering are increases between 2019 ...

BUFFALO, N.Y. — People with substance use disorder who participate in recovery running programs have shown improved success in maintaining their sobriety and reducing their risk for relapse. Those observations led Panayotis Thanos, a University at Buffalo neuroscientist who studies the brain’s reward system, to try to figure out the brain mechanisms behind that phenomenon. In a new study published today in PLOS One, Thanos, PhD, senior research scientist in the Clinical and Research Institute on Addictions in the Jacobs School of Medicine and Biomedical Sciences at UB, and co-authors reveal that ...

Two healthcare workers get COVID-19 vaccinations on the same day. Both show strong antibody responses initially, but six months later one stays healthy while the other contracts the virus. A new study published in Science Translational Medicine could help explain this difference. Researchers tracked individuals’ antibody levels after vaccinations and identified four distinct patterns of immune response after the first booster vaccination. Notably, the group that started with the highest antibody levels but experienced a faster decline were infected earlier. People with lower blood levels of IgA(S) antibodies, ...

A newly developed molecule brings together two powerful immunotherapy strategies in one treatment. Researchers at the University of Basel and University Hospital Basel, Switzerland, have demonstrated that this fusion protein can both block the “do not attack” signal used by cancer cells and selectively activate tumor-fighting immune cells. This dual action could pave the way for more effective cancer therapies with fewer side effects. Back in the early 1980s, Linda Taylor, just 33 years old, was diagnosed with advanced skin cancer and faced a grim prognosis. Luckily, she met Dr. Stephen Rosenberg from the National Cancer Institute in Bethesda, Maryland, who treated ...

People with temporal lobe epilepsy in particular often wander around aimlessly and unconsciously after a seizure. Researchers at the University Hospital Bonn (UKB), the University of Bonn, and the German Center for Neurodegenerative Diseases (DZNE) have identified a neurobiological mechanism that could be responsible for this so-called post-ictal wandering and potentially other postictal symptoms. According to their hypothesis, epileptic seizures are not directly responsible for post-ictal symptoms, but rather seizure-associated depolarization waves, also known as spreading depolarization (SD). The results ...

Musical people find it easier to focus their attention on the right sounds in noisy environments. This is shown in a new study from Karolinska Institutet published in the journal Science Advances. The results suggest that music training can be used to sharpen attention and cognition. Being able to focus on a conversation in a room full of noise is a complex task for the brain. In a new study, researchers have investigated how music training affects the brain's ability to focus attention on specific sounds. The ...

Hydride ion (H⁻), with their low mass and high redox potential, are considered promising charge carriers for next-generation electrochemical devices. However, the lack of efficient electrolyte with fast hydride ion conductivity, thermal stability, and electrode compatibility has hindered their practical applications. In a study published in Nature, Prof. CHEN Ping’s group from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS) developed a novel core–shell hydride ion electrolyte, and constructed the first rechargeable hydride ion ...

CAMBRIDGE, MA -- A genome-editing technique known as prime editing holds potential for treating many diseases by transforming faulty genes into functional ones. However, the process carries a small chance of inserting errors that could be harmful. MIT researchers have now found a way to dramatically lower the error rate of prime editing, using modified versions of the proteins involved in the process. This advance could make it easier to develop gene therapy treatments for a variety of diseases, the researchers say. “This ...

A “teenaged” pachycephalosaur from Mongolia’s Gobi Desert may provide answers to lingering questions around the dinosaur group, according to new research published today in the journal Nature. The fossil represents a new species of pachycephalosaur and is both the oldest and most complete skeleton of this dinosaur group found to date. “Pachycephalosaurs are iconic dinosaurs, but they’re also rare and mysterious,” says Lindsay Zanno, associate research professor at North Carolina State University, head of paleontology at the North Carolina Museum of Natural Sciences and corresponding ...