PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Identifying safer implant designs for total hip replacement

Study reveals key insights on the type of femoral stem that minimizes the risk of early postoperative femoral fracture

2025-10-28
(Press-News.org)

As populations continue to age, total hip replacement (THR) is becoming an increasingly common surgical procedure. Experts estimate that approximately one million THRs are performed each year worldwide. The surgery is often life-changing, as it can fully restore the function of the hip joint, reduce pain, and allow patients to walk and bear weight again. However, as with any major surgery, the procedure is not without risks, especially for older individuals with other health conditions.

 

A significant complication following THR is a femoral fracture—a break in the thigh bone near the artificial hip joint. This is currently the leading cause of reoperation or revision surgery after THR. Nearly half of these fractures occurred early, usually within the first 90 days following surgery. While surgeons have limited control over factors such as their patients’ age, health status, and lifestyle, one critical decision they can influence is the design of the artificial hip implant to use. But which type of hip implant is best at preventing early femoral fractures?

 

In this view, a research team led by Assistant Professor Rui Hirasawa from the Graduate School of Medicine at Chiba University, Japan, conducted a retrospective study comparing the two most widely used types of femoral stems in THR. Their work, published in Volume 107 of the Bone & Joint Journal on October 1, 2025, was co-authored by Dr. Kazuhiro Oinuma, Executive Director of Funabashi Orthopedic Hospital, and Dr. Yoko Miura, Director of the Joint Reconstruction Centre at Funabashi Orthopedic Hospital, as well as Lecturer Shigeo Hagiwara, Associate Professor Junichi Nakamura, and Professor Seiji Ohtori, from Chiba University.

 

The two types of femoral stems compared were collared fully hydroxyapatite (HA)-coated stems and flat-tapered wedge stems. The first type features a stabilizing ring or ‘collar’ at the top of the implant that rests on the patient’s bone, and a specialized coating called HA, designed to promote bone growth directly onto the implant for a secure fit. Meanwhile, flat-tapered stems rely purely on their wedge shape and tight fit within the bone canal of the femur to achieve initial stability; they do not have a stabilizing collar or HA coating. “Based on both our clinical impressions and reports in the literature indicating a lower incidence of post-THR femoral fractures with collared fully HA-coated stems, we were inspired to investigate whether these stems could indeed reduce the risk of these fractures,” explains Dr. Hirasawa.

 

The researchers gathered data from 4,511 THR procedures conducted by a single surgeon in a single medical center from 2009 to 2023. Here, the team used an advanced statistical technique called propensity score matching to produce two highly comparable groups of patients for better analysis. They ultimately matched 1,804 cases where collared HA-coated stems were used with 1,804 cases where flat-tapered wedge stems were used, based on factors such as age, sex, body mass index, and conditions like osteoarthritis. This approach helped minimize the impact of confounding variables.

 

The results revealed that early post-THR femoral fracture was significantly less frequent among patients with collared HA-coated femoral stems—only two cases of fracture were recorded in this group versus 13 in those with flat-tapered wedge stems. Hence, the researchers investigated each fracture in detail based on available clinical data.

 

Notably, while the use of collared HA-coated femoral stems was associated with fewer early postoperative femoral fractures, the study also found that the incidence of intraoperative femoral fractures was higher in this group compared to flat-tapered wedge stems. This highlights the importance of further research to optimize surgical techniques and patient selection when using collared HA-coated stems, in order to minimize intraoperative complications.

 

Overall, the findings of this study suggest that collared HA-coated stems may have inherent advantages over flat-tapered wedge stems, which surgeons should take into account when deciding which type of prosthetic hip to use or recommend. “Our results have the potential to directly improve patient safety and surgical outcomes in THR by helping surgeons make more informed implant selections, leading to fewer serious complications, faster functional recovery, and reduced need for reoperation,” remarks Dr. Hirasawa. “In the long term, this research may set a new global standard for femoral stem selection in hip replacement.”

 

To see more news from Chiba University, click here.

 

About Assistant Professor Rui Hirasawa from Chiba University

Dr. Rui Hirasawa is an Assistant Professor at the Department of Orthopedic Surgery of the Graduate School of Medicine, Chiba University, Japan. His research focuses on conditions such as hip and knee osteoarthritis, osteonecrosis of the femoral head, and rheumatoid arthritis. Specifically, he aims to elucidate the role of the immune system in osteoarthritis and translate this knowledge into better treatments. He is a member of several professional societies, including the Japanese Society of Immunology, the Japanese Society of Artificial Joints, and the Japanese Society of Orthopedic Surgery, among others.

END



ELSE PRESS RELEASES FROM THIS DATE:

Study reveals clinical frailty scale as a quick predictor of patient risk after heart failure administration

2025-10-28
Frailty is closely linked to adverse outcomes in older adults, particularly those with heart failure. Numerous epidemiologic studies show that frailty has important prognostic value in this population, underscoring the need for routine assessment. At the same time, the concept of frailty has expanded beyond the physical domain to include cognitive and other dimensions, making comprehensive evaluation increasingly complex and less feasible in everyday practice. The Clinical Frailty Scale (CFS) offers a practical alternative: a 9-point, bedside, visually assessed tool that can be completed in minutes. However, key questions remain—how closely ...

Game-changing heat shield to revolutionize aerospace manufacturing with long-life engines

2025-10-28
Aerospace industry has undergone tremendous developments over the last century, with materials science engineers playing a significant role in this transformation. It is well known that as the operating temperature of metallic materials increases, the speed of aircraft can be enhanced and fuel consumption can be reduced. Therefore, research on high-temperature materials has been directly linked to the improvement of aircraft performance and has been actively conducted worldwide since the 1940s. For more than 80 years, Ni-based alloys have been the primary materials used for high-temperature applications. To enable their use at even higher temperatures, ...

Pusan National University researchers show how AI can help in fashion trend prediction

2025-10-28
Fashion trend forecasting helps companies predict which clothes will be popular in upcoming seasons. Traditionally, this has relied on experts’ intuition, experience and creativity. More recently, big-data analysis has been incorporated, offering deeper insights into consumer behavior. However, such methods pose technical barriers and remain out of reach for fashion students or small brands. Recent developments in artificial intelligence (AI) can balance the scales. Large language models (LLMs) like ChatGPT have made big data analysis readily available to the public.  LLMs draw ...

Sinking Indian megacities pose 'alarming' building damage risks

2025-10-28
Sinking land is quietly destabilizing urban infrastructure in India’s largest cities, putting thousands of buildings and millions of people at risk, according to Virginia Tech scientists. Groundwater overuse is a critical driver of the problem, said Susanna Werth, assistant professor of geosciences who co-authored the paper published Oct. 28 in Nature Sustainability. “When cities pump more water from aquifers than nature can replenish, the ground quite literally sinks,” Werth said. “Our study shows that this overexploitation ...

Cul-de-sac effect: Why Mediterranean regions are becoming more prone to extreme floods in a changing climate

2025-10-28
Key Messages In May 2023, devastating floods hit Emilia-Romagna, causing deaths, displacement, and estimated damages of €8.5 billion. Cul-de-sac effect: The CMCC research team described for the first time how a specific configuration of mountain topography and circulation patterns trapped moisture coming from the Adriatic, while a stationary cyclone fueled prolonged rains that lasted for several days over the same area, leading to extreme flooding. From the analysis of the Emilia-Romagna case, the ...

Now in 3D, maps begin to bring exoplanets into focus

2025-10-28
ITHACA, N.Y. – Astronomers have generated the first three-dimensional map of a planet orbiting another star, revealing an atmosphere with distinct temperature zones – one so scorching that it breaks down water vapor, a team co-led by a Cornell expert reports in new research. The temperature map of WASP-18b – a gas giant known as an “ultra-hot Jupiter,” located 400 light years from Earth – is the first applying a technique called 3D eclipse mapping, or spectroscopic eclipse mapping. The effort builds on a 2D model that members of the same team published in 2023, which demonstrated eclipse mapping’s potential ...

Researchers develop an ultrasound probe capable of imaging an entire organ in 4D

2025-10-28
For the first time, a team of Inserm researchers from the Physics for Medicine Institute (Inserm/ESPCI Paris-PSL/CNRS) has succeeded in mapping the blood flow of an entire organ in animals (heart, kidney and liver) with great precision, in four dimensions: 3D + time. This new imaging technique, when applied to humans, could both improve our understanding of the circulatory system (veins, arteries, vessels and lymphatic system) and facilitate the diagnosis of certain blood circulation-related diseases. These results are published ...

Oxygen deprivation heightens risk of illness by changing genes

2025-10-28
Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body’s ability to fight infection, new research shows.  Scientists found that oxygen deprivation – known as hypoxia – changes the genetic material of immune cells called neutrophils, reducing their capacity to destroy harmful microbes.  The team discovered that low oxygen appears to leave a lasting mark on the bone marrow cells that produce neutrophils, meaning the impact can persist after oxygen ...

Missing nutrient in breast milk may explain health challenges in children of women with HIV

2025-10-28
A new UCLA study reveals that breast milk from women living with HIV contains significantly lower levels of tryptophan, an essential amino acid likely important for infant immune function, growth, and brain development. This discovery may help explain why children born to women living with HIV experience higher rates of illness and developmental challenges, even when the children themselves are not infected with the virus. The study appears in Nature Communications. Why it matters Approximately 1.3 million children are born to women living with HIV annually worldwide. Even with effective antiretroviral therapy that prevents HIV transmission, these children who ...

Custom-designed receptors boost cancer-fighting T cells

2025-10-28
Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), have revolutionized cancer treatment. But while they’ve delivered impressive results against certain blood cancers, they’ve struggled to make an impact in solid tumors, such as those in the breast, lung, and prostate. The tumor microenvironment is the problem A major problem is the tumor microenvironment (TME), which is a mix of cells and molecules ...

LAST 30 PRESS RELEASES:

New open-source American College of Lifestyle Medicine program brings culinary skills and nutrition education into medicine

AI tool identifies women at high risk of interval breast cancer

USF study: AI and citizen science reveal potential first detection of invasive malaria mosquito in Madagascar

American Pediatric Society honors Dr. Bruce D. Gelb with 2026 APS John Howland Award

Leveraging COVID-19 lessons to prepare for the next pandemic

Mount Sinai awarded $4.5M BD2 grant to advance research on the biology of bipolar disorder

Global initiative to demonstrate operational excellence in Nigeria for metastatic colorectal cancer patients

AI produces shallower knowledge than web search

New study shows global decline in parental trust in childhood vaccines after COVID-19, contributing to increased measles outbreaks

BD² awards $18 million in grants to advance research on the biology of bipolar disorder

Opt-out organ donation policies might reduce organ supply

Message from the oldest-living dogs to dogs and men: Gonad function fights frailty

Distinct brain features in football players may tell who is at risk of long-term traumatic disease

Identifying safer implant designs for total hip replacement

Study reveals clinical frailty scale as a quick predictor of patient risk after heart failure administration

Game-changing heat shield to revolutionize aerospace manufacturing with long-life engines

Pusan National University researchers show how AI can help in fashion trend prediction

Sinking Indian megacities pose 'alarming' building damage risks

Cul-de-sac effect: Why Mediterranean regions are becoming more prone to extreme floods in a changing climate

Now in 3D, maps begin to bring exoplanets into focus

Researchers develop an ultrasound probe capable of imaging an entire organ in 4D

Oxygen deprivation heightens risk of illness by changing genes

Missing nutrient in breast milk may explain health challenges in children of women with HIV

Custom-designed receptors boost cancer-fighting T cells

Polar bears act as crucial providers for Arctic species

Body clocks matter for heart health

Crystal-free mechanoluminescence illuminates new possibilities for next-generation materials

Scientists develop an efficient method of producing proteins from E. coli

AAAS announces addition of Cancer Communications to Science Partner Journal Program

Systematic review reveals psilocybin reduces obsessive-compulsive behaviors across clinical and preclinical evidence

[Press-News.org] Identifying safer implant designs for total hip replacement
Study reveals key insights on the type of femoral stem that minimizes the risk of early postoperative femoral fracture