A conservative dialysis strategy and kidney function recovery in dialysis-requiring acute kidney injury

JAMA

2025-11-07

(Press-News.org) About The Study: A conservative dialysis strategy in dialysis-requiring acute kidney injury resulted in a shorter time to and higher rates of recovery of kidney function in the unadjusted analysis. Given uncertainty regarding the estimated effect size, this approach should be tested in a larger study population.

Author Contact Information: The Corresponding Authors of the study are Kathleen D. Liu, MD, PhD, MAS, and Chi-yuan Hsu, MD, MSc. Suzanne Leigh, Senior Public Information Representative at UCSF, can assist with scheduling interviews. Suzanne can be reached at suzanne.leigh@ucsf.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2025.21530)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Media advisory: This study is being presented at the American Society of Nephrology Kidney Week 2025 meeting.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.21530?guestAccessKey=2de9e862-cd85-418f-81cc-fdf24f37a20a&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110725

END

ELSE PRESS RELEASES FROM THIS DATE:

More Americans, especially Black adults, are dying before they can access Medicare benefits

2025-11-07

PROVIDENCE, R.I. [Brown University] — For 60 years, Medicare has served as a social safety net. Workers pay into the system over their lifetimes with the expectation that they will be able to access affordable health care when they turn 65. But for a growing number of Americans, especially Black Americans, that expectation is going unfulfilled. That’s according to a new study led by researchers at Brown University and Harvard University, which found that a rising number of premature deaths prevent many Americans from reaching the age of Medicare ...

Death Valley plant reveals blueprint for building heat-resilient crops

2025-11-07

In California’s Death Valley, where summer temperatures regularly soar above 120 degrees Fahrenheit, life seems almost impossible. Yet among the cracked earth and blinding sunlight, one native plant not only survives — it thrives. That plant, Tidestromia oblongifolia, has helped Michigan State University scientists uncover how life can flourish in extreme heat, revealing a potential blueprint for engineering crops that can adapt to our changing climate. In a new paper published in Current Biology, Research Foundation Professor Seung Yon “Sue” Rhee and Research ...

Racial disparities in premature mortality and unrealized Medicare benefits across US states

2025-11-07

About The Study: Between 2012 and 2022, premature mortality among adults ages 18 to 64 in the U.S. increased by over 27%. During this period, racial disparities in premature mortality widened substantially, with Black individuals experiencing persistently higher and worsening rates compared with white individuals across most states. These results raise concerns about structural inequities within the Medicare entitlement and financing system. Despite contributing to Medicare throughout their working lives, Black individuals in the U.S. are less likely to ...

Heat- and cold-related mortality burden in the US from 2000 to 2020

2025-11-07

About The Study: In this case series, nonoptimal temperatures were critical environmental contributors associated with mortality burden, with differential vulnerability by geographic location, cause of death, and demographic factors. These findings highlight the need for urgent actions against temperature-related health burdens through tailored climate and public health strategies, considering the local context and demographic profiles. Corresponding Author: To contact the corresponding ...

Research hints at the potential of pain relief with CBD

2025-11-07

Reaching for CBD-infused lotion or oil may seem like a low-risk way to find pain relief, but little is actually known about the impact that CBD has on the nervous system. Over the past decade, the use of cannabis products for pain management has increased, in part because in 2018 Congress signed a law removing hemp from the federal Controlled Substances Act, thereby legalizing hemp-derived CBD. Today, it is most commonly found in oil form, as well as in lotions and cosmetics, and it is widely understood that CBD does not cause a ‘high’. However, what CBD does in the human body and brain is not well understood. Currently, the Food and Drug Administration ...

Dr. Johnson V. John appointed as a Standing Member of the NIH Musculoskeletal Tissue Engineering (MTE) Study Section

2025-11-07

Los Angeles, CA – November 7, 2025 - The Terasaki Institute proudly announces that Johnson V. John, Ph.D., Assistant Professor at the Institute, has been appointed as a standing member of the Musculoskeletal Tissue Engineering (MTE) Study Section within the Center for Scientific Review at the National Institutes of Health (NIH). His four-year term is scheduled to begin in November 2025. The MTE Study Section plays a central role in the NIH’s rigorous peer-review process, evaluating competitive research proposals focused on biomaterials, cellular and molecular strategies, and engineering approaches that drive ...

TCF/LEF transcription factors emerge as druggable targets in Wnt signaling, offering new hope for fibrosis and cancer therapies

2025-11-07

Researchers have unveiled the intricate molecular mechanisms governing TCF/LEF-mediated transcription in the canonical Wnt pathway, identifying these proteins as promising therapeutic targets for cancer and fibrotic diseases. The review, published in Current Molecular Pharmacology, systematically dissects how four mammalian TCF/LEF paralogs—TCF7, LEF1, TCF7L1, and TCF7L2—achieve functional specificity through modular domain architecture and extensive alternative splicing. "TCF/LEF proteins function as the final integrators of Wnt signals, converting β-catenin ...

New alloy design could power solid-state batteries that charge faster and last longer

2025-11-07

A team co-led by engineers at the University of California San Diego has developed a new design strategy for metal alloy negative electrodes that could significantly improve the performance and durability of next-generation solid-state batteries. The work could help advance the path toward practical, high-performance energy storage for electric vehicles. The team focused on negative electrodes made of lithium-aluminum alloy. They studied how lithium ions move through different phases of the material — a lithium-rich “beta” phase and ...

Discovery to display: FAU unveils the ‘Art of Science’ winners

2025-11-07

Science isn’t just a pursuit of knowledge – it’s a canvas of creativity where data, design and exploration converge to reveal the unexpected beauty woven into the very fabric of discovery. Each year, Florida Atlantic University’s Division of Research celebrates creativity with its “Art of Science” contest as research transcends the lab and field to become stunning works of visual expression. The competition invites FAU faculty, students and staff to showcase their research through photography and video, strengthening connections between science, art and the broader community. The Art of Science competition also highlights ...

Achieving electrocatalytic activity toward oxygen reduction reaction based on Ruddlesden-Popper type cathode catalyst for solid oxide fuel cells

2025-11-07

Solid Oxide Fuel Cells (SOFCs) are a new type of fuel cell that directly converts chemical energy into electrical energy and have attracted widespread attention in recent years. However, the slow oxygen reduction reaction (ORR) at the cathode is one of the main factors limiting the electrochemical performance of SOFCs. Ruddlesden-Popper (R-P) oxides have been extensively studied as cathode materials for SOFCs due to their high oxygen mobility and relatively good electrocatalytic activity. Their unique layered structure, characterized by alternating rock-salt layers and perovskite layers, allows them to maintain a large oxygen non-stoichiometry. ...

LAST 30 PRESS RELEASES:

Tracing the quick synthesis of an industrially important catalyst

New software sheds light on cancer’s hidden genetic networks

UT Health San Antonio awarded $3 million in CPRIT grants to bolster cancer research and prevention efforts in South Texas

Manhattan E. Charurat, Ph.D., MHS invested as the Homer and Martha Gudelsky Distinguished Professor in Medicine at the University of Maryland School of Medicine

Insilico Medicine’s Pharma.AI Q4 Winter Launch Recap: Revolutionizing drug discovery with cutting-edge AI innovations, accelerating the path to pharmaceutical superintelligence