Expectant management vs medication for patent ductus arteriosus in preterm infants

JAMA

2025-12-09

(Press-News.org) About The Study: In extremely preterm infants with a protocol-defined patent ductus arteriosus, death or bronchopulmonary dysplasia did not differ between the expectant management group and the active treatment group. Survival was substantially higher with expectant management.

Corresponding Author: To contact the corresponding author, Matthew M. Laughon, MD, MPH, email matt_laughon@med.unc.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2025.23330)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Media advisory: This study is being presented at the Hot Topics in Neonatology 45th Annual Conference.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.23330?guestAccessKey=fac49601-448f-4dfa-8fce-05a66f03f1c9&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=120925

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Expectant management vs medication for patent ductus arteriosus in preterm infants

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