Glucagon-like peptide 1 receptor agonist use and vertebral fracture risk in type 2 diabetes

JAMA Surgery

2025-12-10

(Press-News.org) About The Study: In this cohort of patients with type 2 diabetes, glucagon-like peptide 1 receptor agonist (GLP-1 RA) use was associated with significantly lower risks of vertebral compression fractures and related surgical interventions compared with nonuse, suggesting bone protective benefits of GLP-1 RAs.

Corresponding Author: To contact the corresponding author, Yu Chang, MD, email yuchang111235@gmail.com.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamasurg.2025.5372)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Glucagon-like peptide 1 receptor agonist use and vertebral fracture risk in type 2 diabetes

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