Prescribing patterns of potentially inappropriate central nervous system-active medications in older adults

JAMA

2026-01-12

(Press-News.org) About The Study: Despite decades of guidelines cautioning against their use, many older adults receive potentially inappropriate central nervous system-active medications. Patients with cognitive impairment were more likely than those with normal cognition to receive such medications.

Corresponding Author: To contact the corresponding author, John N. Mafi, MD, MPH, email jmafi@mednet.ucla.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2025.23697)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Prescribing patterns of potentially inappropriate central nervous system-active medications in older adults

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