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Medicine 2026-01-21 1 min read

Antibiotic therapy for uncomplicated acute appendicitis

JAMA
About The Study: Among patients initially treated with antibiotics for uncomplicated acute appendicitis, the rate of recurrence and appendectomy at 10-year follow-up supports the use of antibiotics as an option for uncomplicated acute appendicitis in adult patients.

Corresponding Author: To contact the corresponding author, Paulina Salminen, MD, PhD, email paulina.salminen@varha.fi.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2025.25921)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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