Overdiagnosis of papillary thyroid cancer

JAMA Network Open

2026-02-24

(Press-News.org) About The Study: This study found that thyroid cancer overdiagnosis in the U.S. remains substantial, even after accounting for possible increases in true incidence. This finding suggests an opportunity to reduce unnecessary thyroid ultrasonography referrals, particularly for nonpalpable nodules, and to reduce unnecessary diagnoses and treatment-related harms without increasing mortality.

Corresponding Author: To contact the corresponding author, David O. Francis, MD, MS, email dofrancis@wisc.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.59852)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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Overdiagnosis of papillary thyroid cancer

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