Long COVID and recovery among US adults

JAMA Network Open

2026-03-02

(Press-News.org) About The Study: In 2024, 8.3% of U.S. adults—an estimated 21.3 million—reported ever having long COVID (LC), among whom nearly 6 in 10 reported recovery, consistent with RECOVER initiative findings showing similar LC prevalence in 2023 and 2024 and longitudinal Veterans Affairs data demonstrating declining LC prevalence. Yet many adults, particularly those 35 years or older, continue to experience lasting symptoms. With no LC treatment demonstrating clear efficacy, greater investment in understanding biological mechanisms, including immunotypic differences between those who recover and those who do not, may provide insights into pathways of persistence and potential targets for intervention.

Corresponding Author: To contact the corresponding author, Harlan M. Krumholz, MD, SM, email harlan.krumholz@yale.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2026.0374)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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Long COVID and recovery among US adults

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