Digital microsteps as scalable adjuncts for adults using GLP-1 receptor agonists

JAMA Network Open

2026-03-09

(Press-News.org) About The Study: In this randomized clinical trial, a low-cost digital intervention increased expectation to adopt health behaviors among adults using glucagon-like peptide-1 receptor agonists (GLP-1RAs), with effects persisting for 2 weeks. These findings suggest a potential role for the written microsteps intervention plus short video boosters as adjuncts to pharmacotherapy. Longer trials are warranted to determine whether the behavioral expectations stimulated by such interventions may lead to sustained behavior change.

Corresponding Author: To contact the corresponding author, Maya Adam, MD, PhD, email madam@stanford.edu.

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(doi:10.1001/jamanetworkopen.2026.0577)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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Digital microsteps as scalable adjuncts for adults using GLP-1 receptor agonists

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