PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

1 person of 1,900 met AHA's definition of ideal heart health, says University of Pittsburgh study

2011-02-20
(Press-News.org) PITTSBURGH, Feb. 18 – Only one out of more than 1,900 people evaluated met the American Heart Association (AHA) definition of ideal cardiovascular health, according to a new study led by researchers at the University of Pittsburgh School of Medicine. Their findings were recently published online in Circulation.

Ideal cardiovascular health is the combination of these seven factors: nonsmoking, a body mass index less than 25, goal-level physical activity and healthy diet, untreated cholesterol below 200, blood pressure below 120/80 and fasting blood sugar below 100, explained senior investigator and cardiologist Steven Reis, M.D., associate vice chancellor for clinical research at Pitt.

"Of all the people we assessed, only one out of 1,900 could claim ideal heart health," said Dr. Reis. "This tells us that the current prevalence of heart health is extremely low, and that we have a great challenge ahead of us to attain the AHA's aim of a 20 percent improvement in cardiovascular health rates by 2020."

As part of the Heart Strategies Concentrating on Risk Evaluation (Heart SCORE) study, the researchers evaluated 1,933 people ages 45 to 75 in Allegheny County with surveys, physical exams and blood tests. Less than 10 percent met five or more criteria; 2 percent met the four heart-healthy behaviors; and 1.4 percent met all three heart-healthy factors. After adjustment for age, sex and income level, blacks had 82 percent lower odds than whites of meeting five or more criteria.

A multipronged approach, including change at the individual level, the social and physical environment, policy and access to care, will be needed to help people not only avoid heart disease, but also attain heart health, Dr. Reis said.

"Many of our study participants were overweight or obese, and that likely had a powerful influence on the other behaviors and factors," he noted. "Our next step is to analyze additional data to confirm this and, based on the results, try to develop a multifaceted approach to improve health. That could include identifying predictors of success or failure at adhering to the guidelines."

###

The team includes Claudia Bambs, M.D., M.Sc., Pontificia Universidad Cato´lica de Chile, Santiago, Chile; Kevin E. Kip, Ph.D., University of South Florida, Tampa; Andrea Dinga, M.Ed., R.D., L.D.N., Suresh R. Mulukutla, M.D., and Aryan N. Aiyer, M.D., University of Pittsburgh School of Medicine.

The study was funded by the National Institutes of Health and the Pennsylvania Department of Health.

About the University of Pittsburgh School of Medicine

As one of the nation's leading academic centers for biomedical research, the University of Pittsburgh School of Medicine integrates advanced technology with basic science across a broad range of disciplines in a continuous quest to harness the power of new knowledge and improve the human condition. Driven mainly by the School of Medicine and its affiliates, Pitt has ranked among the top 10 recipients of funding from the National Institutes of Health since 1997 and now ranks fifth in the nation, according to NIH data for 2008 (the most recent year for which the data are final).

Likewise, the School of Medicine is equally committed to advancing the quality and strength of its medical and graduate education programs, for which it is recognized as an innovative leader, and to training highly skilled, compassionate clinicians and creative scientists well-equipped to engage in world-class research. The School of Medicine is the academic partner of UPMC, which has collaborated with the University to raise the standard of medical excellence in Pittsburgh and to position health care as a driving force behind the region's economy. For more information about the School of Medicine, see www.medschool.pitt.edu

END



ELSE PRESS RELEASES FROM THIS DATE:

Anti-aging hormone Klotho may prevent complications

2011-02-20
DALLAS – Feb. 17, 2011 – Low levels of the anti-aging hormone Klotho may serve as an early warning sign of the presence of kidney disease and its deadly cardiovascular complications, according to findings by UT Southwestern Medical Center researchers. Using mice, investigators found that soft-tissue calcification, a common and serious side effect of chronic kidney disease (CKD), improves when Klotho hormone levels are restored. The study is available online in the Journal of the American Society of Nephrology. The essential Klotho protein, which is produced by the kidneys, ...

How disordered proteins spread from cell to cell, potentially spreading disease

How disordered proteins spread from cell to cell, potentially spreading disease
2011-02-20
One bad apple is all it takes to spoil the barrel. And one misfolded protein may be all that's necessary to corrupt other proteins, forming large aggregations linked to several incurable neurodegenerative diseases such as Huntington's, Parkinson's and Alzheimer's. Stanford biology Professor Ron Kopito has shown that the mutant, misfolded protein responsible for Huntington's disease can move from cell to cell, recruiting normal proteins and forming aggregations in each cell it visits. Knowing that this protein spends part of its time outside cells "opens up the possibility ...

A better way to diagnose pneumonia

2011-02-20
Researchers from the Georgia Institute of Technology have created a new sampling device that could prevent thousands of people worldwide from dying of pneumonia each year. Called PneumoniaCheck, the device created at Georgia Tech is a solution to the problem of diagnosing pneumonia, which is a major initiative of the U.S. Centers for Disease Control and Prevention (CDC). Pneumonia, an inflammation of the lungs, kills about 2.4 million people each year. The problem is particularly devastating in Africa, Southeast Asia and the Eastern Mediterranean, where a child dies ...

New model for probing antidepressant actions

2011-02-20
The most widely prescribed antidepressants – medicines such as Prozac, Lexapro and Paxil – work by blocking the serotonin transporter, a brain protein that normally clears away the mood-regulating chemical serotonin. Or so the current thinking goes. That theory about how selective serotonin reuptake inhibitors (SSRIs) work can now be put to the test with a new mouse model developed by neuroscientists at Vanderbilt University. These mice, described in the online edition of the Proceedings of the National Academy of Sciences (PNAS), express a serotonin transporter that ...

Enhancing nuclear security: Training and international collaboration

2011-02-20
While a world free of nuclear weapons remains a goal for governments around the world, nuclear security constitutes a major challenge for the 21st century, as recognised at the 2010 nuclear security summit in Washington. Citizens are generally aware of international efforts to prevent the proliferation of nuclear weapons, but they are often unaware of nuclear security research and the important role science in this field. A new European nuclear security training centre and enhanced international collaboration are good examples. A recent survey on the EU´s radiological ...

Turning to nature for inspiration

2011-02-20
To build the next generation of sensors – with applications ranging from medical devices to robotics to new consumer goods – Chang Liu looks to biology. Liu, professor of mechanical engineering and electrical engineering and computer science at Northwestern University's McCormick School of Engineering and Applied Science, is using insights from nature as inspiration for both touch and flow sensors — areas that currently lack good sensors for recording and communicating the senses. Liu will discuss his research in a symposium at the annual meeting of the American Association ...

Plant breeding is being transformed by advances in genomics and computing

2011-02-20
The arrival of affordable, high throughput DNA sequencing, coupled with improved bioinformatics and statistical analyses is bringing about major advances in the field of molecular plant breeding. Multidisciplinary breeding programs on the world's major crop plants are able to investigate genome-wide variations in DNA sequences and link them to the inheritance of highly complex traits controlled by many genes, such as hybrid vigor. Furthermore, there has been a step-change in speed and cost-effectiveness. What previously took six generations to achieve can now be done in ...

AAAS Symposium: New research facilitates scientific knowledge transfer

2011-02-20
NEW YORK, February 4, 2011 –– A defining feature of a scientific discovery is replication by others. In today's age of computational science, this means higher standards of communication of discoveries — making available the data that generated the results along with the published research paper. Doing this makes the technology behind the finding widely accessible, facilitating re-use and verification of results. Tools and approaches to facilitate such knowledge transfer will be discussed at a symposium titled The Digitization of Science: Reproducibility and Interdisciplinary ...

Weight loss improves knee pain from common arthritic condition, study says

2011-02-20
SAN DIEGO, CA – Knee pain related to osteoarthritis (OA) is a common complaint among obese individuals and retired professional athletes, especially former NFL players, but researchers presenting their work at the American Orthopaedic Society for Sports Medicine's Specialty Day program (February 19th) say they have a simple solution: lose weight. "Our research on patients who were obese with early-onset knee osteoarthritis showed that those individuals who underwent isolated weight loss via bariatric surgery and lost an average of 57 pounds within the first six months ...

Misguided public perception on what Tommy John surgery can do apparent in new study

2011-02-20
SAN DIEGO, CA – Despite known risks and outcomes of the common elbow procedure known as Tommy John surgery, parents, coaches and players still have incorrect assumptions regarding player performance, say researchers presenting their study at the American Orthopaedic Society for Sports Medicine's Specialty Day in San Diego, CA (February 19th). "Despite the recognized risk of pitch type and amount of pitches, nearly a third of those we surveyed did not believe pitch counts were a risk factor for injury. Even more disturbing was that fact that a quarter of players and coaches ...

LAST 30 PRESS RELEASES:

Black youth, especially Black girls, use mental health services less than their White peers

Canada must protect youth from sports betting advertising

First-in-human trial shows promising results for DLL3-targeted antibody-drug conjugate SHR-4849 in relapsed small cell lung cancer

Ifinatamab deruxtecan demonstrates high response rate in previously treated extensive-stage small cell lung cancer: Phase 2 IDeate-Lung01 trial

Higher blood pressure in childhood linked to earlier death from heart disease in adulthood

AI helped older adults report accurate blood pressure readings at home

High blood pressure in childhood and premature cardiovascular disease mortality

Zidesamtinib shows durable responses in ROS1 TKI pre-treated NSCLC, including patients with CNS disease and ROS1 G2032R mutations

Crizotinib fails to improve disease-free survival in resected early-stage ALK+ NSCLC

Ivonescimab plus chemotherapy improves progression-free survival in patients with EGFR+ NSCLC following 3rd-generation EGFR-TKI therapy

FLAURA2 trial shows osimertinib plus chemotherapy improves overall survival in eGFR-mutated advanced NSCLC

Aumolertinib plus chemotherapy improves progression-free survival in NSCLC with EGFR and concomitant tumor suppressor genes: ACROSS 2 phase III study

New antibody-drug conjugate shows promising efficacy in EGFR-mutated NSCLC patients

Iza-Bren in combination with osimertinib shows 100% response rate in EGFR-mutated NSCLC, phase II study finds

COMPEL study shows continuing osimertinib treatment through progression with the addition of chemotherapy improves progression-free survival in EGFR-mutated NSCLC

CheckMate 77T: Nivolumab maintains quality of life and reduces symptom deterioration in resectable NSCLC

Study validates AI lung cancer risk model Sybil in predominantly Black population at urban safety-net hospital

New medication lowered hard-to-control high blood pressure in people with chronic kidney disease

Innovative oncolytic virus and immunotherapy combinations pave the way for advanced cancer treatment

New insights into energy metabolism and immune dynamics could transform head and neck cancer treatment

Pennington Biomedical’s Dr. Steven Heymsfield named LSU Boyd Professor – LSU’s highest faculty honor

Study prompts new theory of human-machine communication

New method calculates rate of gene expression to understand cell fate

Researchers quantify rate of essential evolutionary process in the ocean

Innovation Crossroads companies join forces, awarded U.S. Air Force contract

Using new blood biomarkers, USC researchers find Alzheimer’s disease trial eligibility differs among various populations

Pioneering advances in in vivo CAR T cell production

Natural medicines target tumor vascular microenvironment to inhibit cancer growth

Coral-inspired pill offers a new window into the hidden world of the gut

nTIDE September2025 Jobs Report: Employment for people with disabilities surpasses prior high

[Press-News.org] 1 person of 1,900 met AHA's definition of ideal heart health, says University of Pittsburgh study