(Press-News.org) Surgeon and Professor Michael Olausson was able to create a new connection with the aid of this blood vessel between the liver and the intestines, necessary to cure the girl. The girl is now in good health, and her prognosis is very good. The girl developed during her first year of life a blood clot in the blood vessel that leads blood from the intestines to the liver. This introduced the risk that she would experience life-threatening internal bleeding. The condition can be cured if it is possible to direct the blood along the correct path, back into the liver. In optimal cases, the surgery can be performed using blood vessels from other parts of the patient's body, but a liver transplant may be necessary if the surgery is unsuccessful due to a lack of sufficient blood vessels. A liver transplant will involve subsequent lifelong treatment with immunosuppressive drugs.
Blood vessels from a dead donor were used in the present case. The vessel was then chemically treated to remove all cells RNA and DNA. This left just the supporting tissue. Stem cells were then obtained from the girl's bone marrow and these were added to the supporting tissue. A new blood vessel grew in just under four weeks. This was used during the surgery in order to create the new connection between the liver and the intestines, necessary to cure the girl.
"We carried out the surgery over three months ago now, and the result was very good, with no serious complications. To our knowledge this is the first procedure of this type in the world, says Michael Olausson. The girl is in good health, and we believe that her prognosis is very good. Since the vessel was created with the girl's own stem cells, she does not need to take drugs to prevent rejection", says Michael Olausson at the Transplant Centre, Sahlgrenska University Hospital and professor at the Sahlgrenska Academy.
The procedure shows that it is possible to create new blood vessels from stem cells, using a previous blood vessel as a template. This can lead to the condition that the girl suffered from being treated more easily, and with less risk for the patient. The result of this operation may have implications not only for the condition the girl was suffering from, but also in a number of other fields of research.
"The next step is to intensify research into the recreation of other organs, and to develop methods that can be used for arteries. This can help, among others, patients who need dialysis and those needing surgery for the coronary arteries. It may also help those needing complete organs", says Michael Olausson, who adds:
"There may also be major financial benefits for the healthcare system, particularly if it proves possible to produce, for example, complete kidneys by this method, since the consumption of drugs will be dramatically reduced. For the patients, it means that the undesired effects of the drugs that must currently be used will be avoided."
INFORMATION:
Stem cell technology used in unique surgery
2011-05-10
[Attachments] See images for this press release:
ELSE PRESS RELEASES FROM THIS DATE:
Obesity creates wimpy rats
2011-05-10
Obesity appears to impair normal muscle function in rats, an observation that could have significant implications for humans, according to Penn State researchers.
"Our findings demonstrate that obesity involves more than accumulating excess fat and carrying excess weight," said Rudolf J. Schilder, American Physiological Society postdoctoral fellow in physiological genomics, Penn State College of Medicine. "We show that, during the development of obesity, skeletal muscles fail to adjust their molecular composition appropriately to the increasing body weight. Consequently, ...
Do you think liposuction will get rid of that fat forever?
2011-05-10
AURORA, Colo. (May 8, 2011) Liposuction has become one of the most popular plastic surgeries in the country. It has been around since 1974 and there are now more than 450,000 operations a year. But does the fat come back? A recent study by Teri L. Hernandez, PhD, RN and Robert H. Eckel, MD, at the University of Colorado School of Medicine have found that the fat eventually returns within one year, and is redistributed to other areas of the body, especially the upper abdomen. There was further redistribution around the shoulders and triceps of the arms.
"The fact ...
Parsley, celery carry crucial component for fight against breast cancer, MU researcher finds
2011-05-10
Parsley is usually used as a decorative accent to a scrumptious meal, but don't set it aside just yet. In a new study, a University of Missouri researcher has found that a compound in parsley and other plant products, including fruits and nuts, can stop certain breast cancer tumor cells from multiplying and growing. The study was published recently in Cancer Prevention Research.
In his study, Salman Hyder, the Zalk Endowed Professor in Tumor Angiogenesis and professor of biomedical sciences in the College of Veterinary Medicine and the Dalton Cardiovascular Research Center, ...
Attorneys at Coppola & Marlin, P.C. Named 2011 "Super Lawyers"
2011-05-10
The personal injury attorneys at Denver law firm Coppola & Marlin, P.C. have been prestigiously recognized for their outstanding accomplishments as lawyers. Colorado Super Lawyers named the law firm's partners Frank W. Coppola and William C. Marlin to their exclusive Super Lawyers list using a "rigorous, multiphase rating process" that includes peer evaluation. Only five percent of Colorado attorneys make the list.
Although the Denver personal injury attorneys graciously accept their place amongst the highest-ranking attorneys in Colorado for 2011, they ...
Researchers get new view of how water and sulfur dioxide mix
2011-05-10
EUGENE, Ore. -- (May 9, 2011) -- High in the sky, water in clouds can act as a temptress to lure airborne pollutants such as sulfur dioxide into reactive aqueous particulates. Although this behavior is not incorporated into today's climate-modeling scenarios, emerging research from the University of Oregon provides evidence that it should be.
The role of sulfur dioxide -- a pollutant of volcanic gasses and many combustion processes -- in acid rain is well known, but how sulfur dioxide reacts at the surface of aqueous particulates in the atmosphere to form acid rain is ...
An Overview of Apartment Complex Premises Liability in New York
2011-05-10
Premises liability is one of those legal phrases that can be intimidating, but simply put, it is the duty that New York law places upon property owners to keep their property reasonably safe. This duty can vary according to a variety of factors, often centering on the nature of the property and whether the visitor was invited onto it.
In New York City apartment complex accidents, there are a variety of situations where premises liability comes into play. There are many different ways to categorize premises liability accidents; in this article we will break them down ...
Atlanta Marketing Agency, ALR Marketing Solutions Unveils New Website
2011-05-10
ALR Marketing Solutions, a premier Atlanta marketing agency, is pleased to announce launch of their new web presence at www.ALRMarketingSolutions.com. The new site includes a more comprehensive overview of their services, including Atlanta PR, traditional and Internet Marketing solutions. In addition, the site features web design samples, Atlanta marketing articles, blog and sign-up for Free Marketing Solutions Consultations. Their online visitors can learn more about brand building, market research, PR campaign planning, search engine optimization (SEO), and Pay Per Click ...
Availability of local food key to improving food security
2011-05-10
COLUMBIA, Mo. – Most strategies to assist the hungry, including food banks and providing food stamps through the Supplemental Nutrition Assistance Program, are short-term, emergency solutions. Those who rely on these programs face daily shortages of fresh and healthy foods, which lead to poor diet choices, nutritional deficiencies and health problems. An expert at the University of Missouri says the production of sustainable, locally grown foods is key to providing long-term food security for communities.
"We have to recognize that access to food is a human right," says ...
Step in breakdown of HIV proteins essential to recognition, destruction of infected cells
2011-05-10
A key step in the processing of HIV within cells appears to affect how effectively the immune system's killer T cells can recognize and destroy infected cells. Researchers at the Ragon Institute of MGH, MIT and Harvard have found that – as HIV proteins are broken down within cells, a process that should lead to labeling infected cell for destruction by CD8 T cells – there is a great variability in the stability of resulting protein segments, variations that could significantly change how well cells are recognized by the immune system. Their report appears in the June ...
Supply of hospice services strongly associated with local area's median household income
2011-05-10
This release is available in Spanish.
Ann Arbor, Mich. — Wealth, population size, race and age associate with the supply of hospice care available in a county, according to a study published in the Journal of Pain and Symptom Management this month.
Local availability is an important predictor of use of hospice programs, which are end-of-life services that have been shown to improve pain control, maintain patients' independence and even extend life, says lead author Maria Silveira, M.D., M.P.H., of the Veterans Affairs Ann Arbor Healthcare System and assistant professor ...