PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Comorbidities increase risk of mortality in COPD patients

2012-05-04
(Press-News.org) Comorbidities are common among patients with chronic obstructive pulmonary disease (COPD), and a number of these comorbidities are independently associated with an increased mortality risk, according to a new study.

"We followed 1,664 COPD patients recruited from five pulmonary clinics in the United States and Spain for a median of 51 months," said lead author Miguel Divo, MD, a physician in the Pulmonary and Critical Division at Brigham and Women's Hospital and Instructor in Medicine at Harvard Medical School. "Among the 79 comorbidites we observed in these patients, 12 were significantly and independently associated with an increased risk of death."

The 12 comorbidities with the strongest association with an increased risk for death were lung cancer, pancreatic cancer, esophageal cancer, breast cancer, pulmonary fibrosis, atrial fibrillation/flutter, congestive heart failure, coronary artery disease, gastric/duodenal ulcers, liver cirrhosis, diabetes with neuropathy and anxiety.

"We used these 12 comorbidities to develop a new comorbidity risk index (the COPD specific CO-morbidity Test, or COTE)," Dr. Divo said. "After adjustment for age, gender, race, and BODE (Body Mass Index; FEV1; Dyspnea and Exercise capacity) index, an increased COTE index was a significant predictor of death in our cohort of COPD patients."

The findings were published online ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

The average number of comorbidities per subject in the cohort overall was 6.0 (±3.5), and the average number of comorbidities was significantly higher among non-survivors (6.5 ±3.8) compared with survivors (5.8 ±3.3).

"These easily identifiable comorbidities could be screened by health care providers caring for COPD patients, as there may be effective interventions that may help decrease the risk of death," Dr. Divo said.

The study had some limitations. The proportion of women included in the study (11 percent) was low. Some patients were excluded at baseline because of comorbidities that might cause early death, including a recent myocardial infarction, severe congestive heart failure, and untreated cancer. Finally, patients were recruited from specialty clinics, and so might not represent all COPD patients.

"In this study we have confirmed earlier observations that patients with COPD frequently suffer from comorbidities, and have shown that 12 specific comorbidities are associated with an increased mortality risk in these patients," Dr. Divo concluded. "The simple comorbidity risk index we developed based on these 12 comorbidities complements the BODE index and can be used to help predict an increased risk of death in COPD patients in both clinical and research settings."

INFORMATION:

About the American Journal of Respiratory and Critical Care Medicine:

With an impact factor of 10.191, the AJRRCM is a peer-reviewed journal published by the American Thoracic Society. It aims to publish the most innovative science and the highest quality reviews, practice guidelines and statements in the pulmonary, critical care and sleep-related fields.

Founded in 1905, the American Thoracic Society is the world's leading medical association dedicated to advancing pulmonary, critical care and sleep medicine. The Society's 15,000 members prevent and fight respiratory disease around the globe through research, education, patient care and advocacy.

END



ELSE PRESS RELEASES FROM THIS DATE:

Beehive extract shows potential as prostate cancer treatment

2012-05-04
An over-the-counter natural remedy derived from honeybee hives arrests the growth of prostate cancer cells and tumors in mice, according to a new paper from researchers at the University of Chicago Medicine. Caffeic acid phenethyl ester, or CAPE, is a compound isolated from honeybee hive propolis, the resin used by bees to patch up holes in hives. Propolis has been used for centuries as a natural remedy for conditions ranging from sore throats and allergies to burns and cancer. But the compound has not gained acceptance in the clinic due to scientific questions about ...

Brand-new Animated PowerPoint Templates

Brand-new Animated PowerPoint Templates
2012-05-04
Impress your audience with new Animated PowerPoint Templates! SmileTemplates.com create ready-made templates for help create presentation within 30 minutes. Templates available for category such us: business concepts, medical, technology, education, etc. Prove to all, that you are leaders, market conquerors! Use Animated PowerPoint Template and achieve the success! Give your presentation the "WOW" factor PowerPoint templates that will make your presentation look impressive and stunning. Simply include your texts, images and contents into already pre-designed ...

Networking Events At Hilton Hotel Teaches Business Owners How To Sell To Hotel Guests

2012-05-02
YouDeserveToBePampered.com has teamed up with the Digital Ad Portal to produce Networking @ The Hilton Vaughan, a monthly networking event for business owners and marketing professionals who wish to "mingle" with small to large business owners who have made the leap and are investing in "place based marketing" and social media solutions. According to O'Neil McLean, President, Digital Ad Portal, "We bring leaders into a room, discuss the trends driving the industry—and introduce you to best practices for growing your business and brand." In ...

Trichologists Finding Dandruff Solution From Scalpure

2012-05-02
Dandruff is a scalp issue that effects millions of men and women around the World. The most recognized form of treatment for dandruff is medicated shampoo that can be found at mass retail locations. While these treatments can be effective, often people look for natural solutions to problems like dandruff. Scalpure is a company that makes the scalp the focus when developing and manufacturing products. The Scalpure Pure Rejuvenation Mask is a product that is getting rave reviews from trichologists and stylists because of how much it is helping their clients with scalp issues ...

DirectAvenue will be sponsoring Response Expo 2012

2012-05-02
DirectAvenue, which specializes in short form direct response television advertising (DRTV), has chosen to express their commitment to education and collaboration within the direct marketing industry by sponsoring Response Expo 2012. DirectAvenue's logo will be featured on water bottles provided throughout the event. In anticipation of the event, President, CEO and Founder Scott Kowalchek stated: "DirectAvenue looks forward to being a sponsor of the Response Expo again this year. It will be great to listen and learn from this year's Keynote Speaker John Foley, a ...

Manuka Beeswax Candles by Honeymark

2012-05-02
Paraffin candles are the most commonly burned candles but they are also the most dangerous to our health. Paraffin is an inexpensive sludge waste product that is derived from petroleum. It is bleached then texturized with carcinogenic substances. Once burned, paraffin candles release toxins into the air that are known as carcinogens. These toxins are then inhaled by anyone in the same room and linger in the areas that they are burned in. In addition, their soot leaves a residue on walls, discoloring fabrics and ceilings. In fact, soot from paraffin candles contain many ...

GoldKey USB Security Tokens Provide Advanced Authentication for FBI Mandate

2012-05-02
GoldKey Security Corporation announced today that GoldKey USB Security Tokens have passed the FBI vetting process to provide Advanced Authentication as part of the CJIS Security Policy compliance strategy for the City of Marysville, WA, Police Department. The recent Criminal Justice Information Services (CJIS) Security Policy has mandated the use of Advanced Authentication for all law enforcement personnel accessing CJIS, a computerized information system that is part of the FBI's National Crime Information Center. CJIS is utilized by state, local, and federal law enforcement ...

Hoag Orthopedic Institute's Dr. James Caillouette Honored With Founders' Award from California Orthopedic Association

2012-05-02
The California Orthopedic Association has honored Dr. James T. Caillouette, Surgeon in Chief at Hoag Orthopedic Institute in Irvine, with the association's prestigious 2012 Founders' Award, an honor given once a year to an individual who has exemplified the group's high standards for leadership in the field of orthopedics. Among the numerous accomplishments credited to Dr. Caillouette by the association was his leadership in the merger of two state-of-the-art surgical centers and other entities into Hoag Orthopedic Institute, one of only a few such health care models ...

Two Independent Hip Hop Producers From Brooklyn 11223 Utilize Breakthrough Technology That Enables Rappers Across The Globe To Download Beats Instantly

2012-05-02
Lucky Lukie and Andie Starz of Cash Castle Productions founded in 2010 have adopted a lightning fast digital delivery system to download beats to their customers' email. The breakthrough technology is fully automated and makes browsing and selecting beats a user-friendly experience. When a client downloads an instrumental, they receive the license and download link instantly. The variety of Hip Hop beats in their online catalog is high-octane fuel for beat seekers. The sound of this producer duo has a grainy analog vibe, as if they recorded on that good ole Ampex ...

Indiana Criminal Practice Rules, Courtroom Quick Reference Now Available From Summit Legal Publishing

2012-05-02
Indiana Criminal Practice Rules, Courtroom Quick Reference joins a growing lineup of legal reference materials for Indiana practitioners, including Indiana Court Rules 2012. This book is the newest edition to Summit Legal Publishing's Courtroom Quick Reference series. Combining the full text of the Indiana Evidence Rules, Indiana Criminal Procedure Rules, Federal Evidence Rules, restyled in December 2011, and Federal Criminal Procedure Rules, this edition is an invaluable tool for criminal attorneys in Indiana practicing in both state and federal courts. All material in ...

LAST 30 PRESS RELEASES:

No strong evidence for alternative autism treatments, study finds

New self-assembling material could be the key to recyclable EV batteries

An ancient signpost: Minute fossils tell big story about arthropod evolution

Predictable structures in music synchronises blood pressure the most, and could be used to create personalized music-based cardiovascular therapies  

New systematic review and meta-analysis shows an association between shingles vaccination and lower risk of heart attack and stroke 

Food for thought: Using food delivery services to provide rapid cardiac arrest response and potentially save lives

College drinking linked to poor academics, mental health for those around the drinker: Study

Nearly 80% of whale sharks in this marine tourism hotspot have human-caused scars

Spider uses trapped fireflies as glowing bait to attract more prey

How AI can build bridges between nations, if diplomats use it wisely

80% of Americans don’t know early-stage prostate cancer often has no symptoms

Researchers engineer ureter tissue from stem cells, paving way for transplantable kidneys

Strong, evidence-based leadership at CDC essential in wake of director’s exit, says SHEA

Birdwatching tourism is booming. Some countries are benefiting, while others are left behind

High protein or Trp diet increases the risk of cancer-associated venous thromboembolism

Risk of a second cancer after early breast cancer is low

Genetic key to why immune responses differ between men and women

Discovery could lead to new treatments for life-threatening allergic reactions

CRF announces TCT 2025 late-breaking clinical trials and science

Ancient DNA reveals farming spread through migration, locals slow to adopt it

Researchers turn mouse scalp transparent to image brain development

New research reveals longevity gains slowing, life expectancy of 100 unlikely

Wheat that makes its own fertilizer

Certain communities of pond plants may increase greenhouse gases

Hormone therapy type matters for memory performance after menopause

Stroke risk highest among Native Hawaiian, Pacific Islander people

Scientists reveal warped protoplanetary discs, reshaping ideas about how planets form

Be it feast or famine, orangutans adapt with flexible diets

Insomnia patients report better sleep when taking cannabis-based medical products

Intrusive distracting thoughts may be associated with anxiety and linked to lower well-being, and occur more often when alone than in company

[Press-News.org] Comorbidities increase risk of mortality in COPD patients