PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

ICU stays for worst asthma drop 74 percent, review finds

Education, medication compliance cited in lower number of unit admissions

2012-05-11
(Press-News.org) SAN ANTONIO (May 10, 2012) — A review of 30 years of life-threatening asthma cases in a San Antonio intensive care unit found that annual ICU admissions for the condition have dropped 74 percent. The study, by UT Medicine San Antonio physicians who reviewed cases at University Hospital between 1980 and 2010, also showed intubation in the emergency department to help patients breathe did not result in longer hospital stays.

UT Medicine is the clinical practice of the School of Medicine at The University of Texas Health Science Center San Antonio.

Faculty studied inpatient care of status asthmaticus at University Hospital. Patients with this condition experience respiratory failure because their asthma is not responding to standard therapies.

To review status asthmaticus cases, the team extracted all notes and orders from an electronic medical record. This showed 227 patients were admitted to the medical intensive care unit with 280 episodes of status asthmaticus over the three decades. Encouragingly, the hospital analysis showed only one death — and it was of a different cause after the asthma improved.

Patients making wise choices

"The main reason for the decline in cases is that more of our patients are taking their controller medications such as inhaled corticosteroids, which reduce the amount of inflammation in the airways," said lead author Jay I. Peters, M.D., professor and chief of pulmonary diseases in the School of Medicine.

In a separate study of 1,000 children and adults, 70 percent of asthma patients reported routinely taking their corticosteroids. Dr. Peters credited this high rate of compliance to asthma education programs provided in neighborhood clinics, including patient care facilities in the University Health System.

"Studies show if you use your corticosteroid at least 11 months out of the year your risk of dying from asthma comes down exponentially," Dr. Peters said. "Many times asthmatics don't comply because they feel fairly good on a daily basis, but the steroids reduce the risk of exacerbations and death."

Pulmonary physicians thought too many asthmatics were intubated in emergency departments, leading to longer hospital stays. Intubation is insertion of a tube to increase airflow. Previous studies in the medical literature concluded asthmatics should not be intubated because of increased risk of complications such as pneumonia.

Don't be afraid to intubate

In the San Antonio study, patients were intubated either because they quit breathing or their carbon dioxide levels had risen dangerously. High carbon dioxide causes blood to be acidic, and irregular heartbeat can result when acid is elevated. This raises the risk of cardiac arrest.

According to the data, few patients suffered complications after being intubated. "I think our methods of treating patients in the emergency department have improved so much that previous studies of issues with intubation don't hold up anymore," Dr. Peters said.

"On the front end, this study reinforces the importance of staying on controller medications," he said. "On the back end, it shows low mortality for patients in the medical ICU and that we don't need to be afraid to intubate patients and place them on mechanical ventilation if necessary."

###The study is described in Respiratory Medicine. http://www.ncbi.nlm.nih.gov/pubmed/22188845

On the Web and Twitter

For current news from the UT Health Science Center San Antonio, please visit our news release website or follow us on Twitter @uthscsa.

About UT Medicine San Antonio

UT Medicine San Antonio is the clinical practice of the School of Medicine at the UT Health Science Center San Antonio. With more than 700 doctors – all faculty from the School of Medicine – UT Medicine is the largest medical practice in Central and South Texas, with expertise in more than 60 different branches of medicine. Primary care doctors and specialists see patients in private practice at UT Medicine's flagship clinical home, the Medical Arts & Research Center (MARC), located in the South Texas Medical Center at 8300 Floyd Curl Drive, San Antonio 78229. Most major health plans are accepted, and there are clinics and physicians at several local and regional hospitals, including CHRISTUS Santa Rosa, University Hospital and Baptist Medical Center. Call (210) 450-9000 to schedule an appointment, or visit the website at www.UTMedicine.org for a complete listing of clinics and phone numbers.

About the University Health System Owned by the people of Bexar County, University Health System is a nationally recognized academic medical center. In partnership with UT Medicine San Antonio, the clinical practice of the School of Medicine at the UT Health Science Center San Antonio, it is consistently recognized as a leader in advanced treatment options, new technologies and clinical research.


ELSE PRESS RELEASES FROM THIS DATE:

UF study finds logging of tropical forests needn't devastate environment

2012-05-11
GAINESVILLE, Fla. — Harvesting tropical forests for timber may not be the arch-enemy of conservation that it was once assumed to be, according to a new study led by a University of Florida researcher. Selective logging may be one of the few feasible options left for conserving tropical forests given the huge financial incentives pushing tropical landholders to convert primary forests into cash-generating agricultural plantations. The report analyzed data from more than 100 studies of tropical forests on three continents that had been harvested for timber. Results ...

CNIO researchers describe a new target for developing anti-angiogenic and anti-tumoral therapies

2012-05-11
Researchers from the Spanish National Cancer Research Centre (CNIO), led by Jorge L. Martínez-Torrecuadrada from the Proteomics Unit, have demonstrated that the antibody-based blocking of ephrinB2, a protein involved in angiogenesis and lymphoangiogenesis, may represent an effective strategy for the development of antiangiogenic and antitumoural therapies. The results of this study appeared in this month's issue of Blood, the journal of the American Society of Hematology. CNIO researchers generated highly-specific human antibodies against ephrin-B2 using a phage display ...

Nanotube 'sponge' has potential in oil spill cleanup

2012-05-11
A carbon nanotube sponge that can soak up oil in water with unparalleled efficiency has been developed with help from computational simulations performed at the Department of Energy's (DOE's) Oak Ridge National Laboratory. Carbon nanotubes, which consist of atom-thick sheets of carbon rolled into cylinders, have captured scientific attention in recent decades because of their high strength, potential high conductivity and light weight. But producing nanotubes in bulk for specialized applications was often limited by difficulties in controlling the growth process as well ...

New report illustrates impact of sequestration to medical research

2012-05-11
The report "Sequestration: Health Research at the Breaking Point," released today by Research!America, demonstrates the damaging consequences of potential automatic spending cuts, or sequestration, to the nation's medical research enterprise and public health, and offers examples on how these cuts would delay scientific discoveries that could lead to new treatments and cures for deadly diseases. This report provides: The estimated budget cuts to the National Institutes of Health, the Centers for Disease Control and Prevention, the Agency for Healthcare Research and ...

Dawn reveals complexities of ancient asteroidal world

Dawn reveals complexities of ancient asteroidal world
2012-05-11
TEMPE, Ariz. – New findings from NASA's Dawn spacecraft lay the groundwork for the first geological overview of asteroid (4)Vesta and confirm the existence of not one but two giant impact basins in its southern hemisphere. The findings, published today in a set of Science papers, will help scientists better understand the early solar system and processes that occurred as it formed and evolved. The Dawn spacecraft, orbiting asteroid Vesta since July 2011, has already acquired several thousand images of the asteroid's surface, revealing a complex landscape. The images ...

Patients see benefits and risks to direct-to-consumer genetics tests

2012-05-11
MAYWOOD, Ill. – Patients see potential benefits from direct-to-consumer genetic testing, but are also concerned about how test results will be used, and generally are unwilling to pay more than $10 or $20 for them, according to focus groups conducted by researchers at Loyola University Chicago Stritch School of Medicine. Findings by first author Katherine Wasson, PhD, MPH, and colleagues are published in the American Journal of Bioethics Primary Research. Wasson, an assistant professor in Loyola's Neiswanger Institute for Bioethics and Health Policy, is an expert on the ...

New research on seaweeds shows it takes more than being flexible to survive crashing waves

New research on seaweeds shows it takes more than being flexible to survive crashing waves
2012-05-11
Seaweeds are important foundational species that are vital both as food and habitat to many aquatic and terrestrial shore organisms. Yet seaweeds that cling to rocky shores are continually at risk of being broken or dislodged from their holds by crashing waves with large hydrodynamic forces. So how do such seaweeds survive in intertidal zones? Do they have special properties that make them extremely flexible or particularly strong? Patrick Martone (University of British Columbia) has spent a considerable amount of time standing on the shore watching big waves crash ...

You're beautiful, Vesta

2012-05-11
When UCLA's Christopher T. Russell looks at the images of the protoplanet Vesta produced by NASA's Dawn mission, he talks about beauty as much as he talks about science. "Vesta looks like a little planet. It has a beautiful surface, much more varied and diverse than we expected," said Russell, a professor in UCLA's Department of Earth and Space Sciences and the Dawn mission's principal investigator. "We knew Vesta's surface had some variation in color, but we did not expect the diversity that we see or the clarity of the colors and textures, or their distinct boundaries. ...

A push from the Mississippi kept Deepwater Horizon oil slick off shore, Penn research shows

2012-05-11
PHILADELPHIA — When the Deepwater Horizon drilling rig exploded April 20, 2010, residents feared that their Gulf of Mexico shores would be inundated with oil. And while many wetland habitats and wildlife were oiled during the three-month leak, the environmental damage to coastal Louisiana was less than many expected, in part because much of the crude never made it to the coast. Research by a trio of geoscientists, including the University of Pennsylvania's Douglas Jerolmack, now offers an explanation for why some of the oil stayed out at sea. Using publicly available ...

NASA's IBEX reveals a missing boundary at the edge of the solar system

NASAs IBEX reveals a missing boundary at the edge of the solar system
2012-05-11
For the last few decades, space scientists have generally accepted that the bubble of gas and magnetic fields generated by the sun – known as the heliosphere – moves through space, creating three distinct boundary layers that culminate in an outermost bow shock. This shock is similar to the sonic boom created ahead of a supersonic jet. Earth itself certainly has one of these bow shocks on the sunward side of its magnetic environment, as do most other planets and many stars. A collection of new data from NASA's Interstellar Boundary Explorer (IBEX), however, now indicate ...

LAST 30 PRESS RELEASES:

3D printing breakthrough: Scientists create functional human islets for type 1 diabetes treatment

Malnutrition in children rises when economy drops

New model enables the study of how protein complex influences mitochondrial function

Device study offers hopes for spinal cord injuries

How urea forms spontaneously

Mayo Clinic’s AI tool identifies 9 dementia types, including Alzheimer’s, with one scan

Gene therapy improves blood flow in the brain in patients with sickle cell disease

Building breast tissue in the lab to better understand lactation

How gut bacteria change after exposure to pesticides

Timepoint at which developing B-cells become cancerous impacts leukemia treatment

Roberto Morandotti wins prestigious IEEE Photonics Society Quantum Electronics Award 

New urine-based tumor DNA test may help personalize bladder cancer treatment

How a faulty transport protein in the brain can trigger severe epilepsy

Study reveals uneven land sinking across New Orleans, raising flood-risk concerns

Researchers uncover novel mechanism for regulating ribosome biogenesis during brain development

RNA codon expansion via programmable pseudouridine editing and decoding

Post-diagnosis emergency department presentation and demographic factors in malignant skin cancers

A new genetic tuner for embryo development

Insurance churn and the COVID-19 pandemic

Postpartum Medicaid use in birthing parents and access to financed care

Manufacturing chemicals via orthogonal strategy, making full use of waste plastic resources in real life

Study overturns long-held belief about shape of fish schools

Precision oncology Organ Chip platform accurately and actionably predicts chemotherapy responses of patients suffering from esophageal adenocarcinoma

Verify the therapeutic effect of effective components of lycium barbarum on hepatocellular carcinoma based on molecular docking

Early intervention changes trajectory for depressed preschoolers

HonorHealth Research Institute presents ‘monumental’ increase in survivability for patients suffering ultra-low blood pressure

Mitochondrial dynamics in breast cancer metastasis: From metabolic drivers to therapeutic targets

Removing out-of-pocket fee improves access to 3D mammography

Does reducing exposure to image and video content on messaging apps reduce the impact of misinformation? Yes and no

A global microbiome preservation effort enters its growth phase

[Press-News.org] ICU stays for worst asthma drop 74 percent, review finds
Education, medication compliance cited in lower number of unit admissions