PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

A study demonstrates that ibuprofen improves bone repair after surgery or a fracture

2012-07-04
(Press-News.org) A study conducted at the University of Granada hasdemonstrated that ibuprofen ­–a non-steroidal anti-inflammatory drug (NSAID)­– has beneficial effects on bone repair after afracture or following bone surgery.

In vitro tests demonstrated that –unlike other NSAIDs– when a therapeutic dose of ibuprofen is administered, it has no negative effects on the proliferation and synthesis of obsteoblast osteocalcin, a cell which is directly involved in the formation and regeneration of bones.

Osteoblast cells are bone cells that synthesize the bone matrix. Consequently, osteoblasts play a major role in bone development, growth, maintenance and repair.

Positive Results

In an article recently published in the prestigious Journal of Bone and Mineral Metabolism, the University of Granada researchers report the positive effects of ibuprofen on bone repair. The researchers are members of the research group BIO277, which studies the effects of different pharmacological and non-pharmacological therapies on obsteoblast cells.

The primary author of this article, Concepción Ruiz Rodríguez, a professor at the University of Granada Nursing Department states that "up to date, we had little information on the effects of ibuprofen on osteoblast cells". The University of Granada study demonstrates that a therapeutic dose of ibuprofen (5-25µm.) does not inhibit the proliferation and synthesis of osteocalcinin the MG-63 cell line. However, when higher doses are administered (>25 µm.) they may activate other cells, which might explain theexpression of membrane markers and the decrease in the phagocytic capacity.

INFORMATION:

Reference: This article is available at: http://www.ncbi.nlm.nih.gov/pubmed/22543821

Contact: Concepción Ruiz Rodríguez. University of Granada Department of Nursing. Phone Number: +34 958 243 497. E-mail: crr@ugr.es

END



ELSE PRESS RELEASES FROM THIS DATE:

What's cooking? The UK's potential food crisis

2012-07-04
The Sustainable Consumption Institute research claims food which families now take for granted, such as meat and fresh vegetables, could become too expensive for many if global temperatures rise in line with the current trends and reach 4°C within the lifetime of many people. Even if families continue to take steps to lower their carbon emissions from energy use, global farming emissions will continue to rise because of our growing appetite for energy-intensive foods and a rising demand to meet just basic living standards across the world. Only by reducing consumption ...

The big sleep

2012-07-04
All zoo animals – and sometimes also wild animals – occasionally need veterinary treatment and anaesthesia is clearly required in many cases. For most animals the procedures are well established but for a variety of reasons it has proven difficulty to anaesthetize hippopotamuses. The thick skin and the dense subcutaneous tissue make it difficult to introduce sufficient amounts of anaesthetics and opioid-based anaesthetics often cause breathing irregularities and occasionally even death. In addition, the level of anaesthesia is only rarely sufficient to enable surgery to ...

Searching for an ancient syphilis DNA in newborns

2012-07-04
The ancient bones of newborns are very useful to recover the ancient DNA of the bacteria causing syphilis, the Treponema pallidum pallidum. This is the conclusion reached by a study led by Universitat Autònoma de Barcelona (UAB), which was able to obtain the genetic material from the bacteria in more than one individual, in what is considered to be the oldest case known to date. Several previous intents had only achieved to yield this material in one occasion and from only one individual. Studying syphilis represents a challenge for researchers, in part because of the ...

Rising plasma offers clues to sun storms

2012-07-04
Doppler measurements that help track storms on Earth may also be useful for understanding storms on the sun. A Rice University astrophysicist is part of an international team that combined Doppler techniques with images and data from a space-based telescope to observe, for the first time, loops of 1,800,000-degree Fahrenheit plasma flowing up from the sun's surface at more than 12 miles per second. The loops, rooted in active regions near sunspots and guided by the sun's magnetic field, arch over the sun and may be the first signs of trouble spots, where plasma undergoes ...

Feathered saurians -- downy dinosaur discovered

2012-07-04
The new fossil find from the chalk beds of the Franconian Jura evokes associations with a pet cemetery, for the young predatory dinosaur reveals clear traces of fluffy plumage. It also poses an intriguing question: Were all dinosaurs dressed in down? The fossil of the fledgling saurian, probably newly hatched when it met its end, is remarkable in many ways. First of all, juveniles are extremely rare in the dinosaur fossil record, so every new discovery provides insights into dinosaur nurseries. Moreover, this specimen is perhaps the best-preserved predatory dinosaur that ...

Toward an alternative for antibiotics to fight bacterial infections?

2012-07-04
VIB researcher Mohamed Lamkanfi, connected to the Ghent University, discovered that mice that do not produce the receptor protein NLRP6, are better protected against bacterial infections and can easier remove bacteria from the body. Therapeutic drugs that neutralize NLRP6 could be a possible treatment option, in addition to the use of antibiotics, for fighting bacterial infections. His research was published in the leading scientific magazine Nature. Mohamed Lamkanfi (VIB – Ghent University): "Our lab investigates the role of the innate immunity, which is of crucial importance ...

Parents less likely to develop colds, Carnegie Mellon research shows

2012-07-04
PITTSBURGH—There is no question that being a parent is, at times, challenging both physically and mentally. However knowledge of the actual affect parenthood has on health has been inconsistent at best, until now. New research led by Carnegie Mellon University's Sheldon Cohen and Rodlescia S. Sneed shows that being a parent influences health in a positive way. Published in Psychosomatic Medicine, the research provides the first evidence that, when exposed to a common cold virus, parents are 52 percent less likely to develop a cold than non-parents. "We have had a long-term ...

Oh, baby! A young star flaunts its X-ray spots in McNeil's Nebula

2012-07-04
X-ray observations have revealed something curious about the young star that illuminates McNeil's Nebula, a glowing jewel of cosmic dust in the Orion constellation: The object is a protostar rotating once a day, or 30 times faster than the sun. The stellar baby also has distinct birthmarks—two X-ray-emitting spots, where gas flows from a surrounding disk, fueling the infant star. The young star, V1647 Orionis, first made news in early 2004, when it erupted and lit up McNeil's Nebula, located 1,300 light years away in a region of active star formation within the constellation ...

Highlighting molecular clues to the link between childhood maltreatment and later suicide

2012-07-04
Philadelphia, PA, July 3, 2012 – Exposure to childhood maltreatment increases the risk for most psychiatric disorders as well as many negative consequences of these conditions. This new study, by Dr. Gustavo Turecki and colleagues at McGill University, Canada, provides important insight into one of the most extreme outcomes, suicide. "In this study, we expanded our previous work on the epigenetic regulation of the glucocorticoid receptor gene by investigating the impact of severe early-life adversity on DNA methylation," explained Dr. Turecki. The glucocorticoid receptor ...

SMOS satellite measurements improve as ground radars switch off

2012-07-04
Over a dozen radio signals that have hindered data collection on ESA's SMOS water mission have been switched off. The effort also benefits satellites such as NASA's Aquarius mission, which measures ocean salinity at the same frequency. We all know what happens when you place a cell phone too close to a speaker: seconds before the phone rings, that obnoxious buzz interrupts your favourite song. This is radio interference – an unwanted reception of radio signals. Not only can it interrupt the music from your stereo, it can also impede satellite measurements. ESA's ...

LAST 30 PRESS RELEASES:

Research unearths origins of Ancient Egypt’s Karnak Temple

Reevaluating nonoperative management for pediatric uncomplicated acute appendicitis

Metabolically active visceral fat linked to aggressive endometrial cancer, new study reveals

Scientists glimpse how enzymes “dance” while they work, and why that’s important

California partnership aided COVID-19 response and health equity, report finds

University of Oklahoma secures $19.9 million for revolutionary radar technology

Study finds restoring order to dividing cancer cells may prevent metastasis

High-accuracy tumor detection with label-free microscopy and neural networks

Wayne State research reveals fetuses exposed to Zika virus have long-term immune challenges

Researchers deconstruct chikungunya outbreaks to improve prediction and vaccine development

Study finds one-year change on CT scans linked to future outcomes in fibrotic lung disease

Discovery of a novel intracellular trafficking pathway in plant cells

New tool helps forecast volcano slope collapses and tsunamis

Molecular coating cleans up noisy quantum light

From Parkinson's to rare diseases, discovered a key switch for cellular health

Tiny sugars in the brain disrupt emotional circuits, fueling depression

Mini-organs reveal how the cervix defends itself

Africa, climate, and food: How to feed a continent without increasing its carbon footprint

Researchers demonstrates substrate design principles for scalable superconducting quantum materials

How better software choices could cut US health care costs

Concussion history in NCAA athletes yields mixed health outcomes

Counting plastic reveals hidden waste and sparks action

Warming oceans may pose a serious threat to American lobsters

Deaths from drug-induced unintentional injury rise across the US

In car crashes with pedestrians, age and zip code may predict extent of traumatic injuries

AI optimizes evacuation, diagnosis, and treatment of wounded soldiers in Ukraine

Mastectomy linked to worsened sexual health, body image after surgery

Drop in credit score after cancer diagnosis linked to increased mortality, study shows

Use of weight loss drugs before bariatric surgery has soared in recent years, study finds

EMS call times in rural areas take at least 20 minutes longer than national average

[Press-News.org] A study demonstrates that ibuprofen improves bone repair after surgery or a fracture