(Press-News.org) BETHESDA, MD – November 30, 2012 -- Using genetic analyses, scientists have discovered that Northern European populations—including British, Scandinavians, French, and some Eastern Europeans—descend from a mixture of two very different ancestral populations, and one of these populations is related to Native Americans. This discovery helps fill gaps in scientific understanding of both Native American and Northern European ancestry, while providing an explanation for some genetic similarities among what would otherwise seem to be very divergent groups. This research was published in the November 2012 issue of the Genetics Society of America's journal GENETICS (http://www.genetics.org).
According to Nick Patterson, first author of the report, "There is a genetic link between the paleolithic population of Europe and modern Native Americans. The evidence is that the population that crossed the Bering Strait from Siberia into the Americas more than 15,000 years ago was likely related to the ancient population of Europe."
To make this discovery, Patterson worked with Harvard Medical School Professor of Genetics David Reich and other colleagues to study DNA diversity, and found that one of these ancestral populations was the first farming population of Europe, whose DNA lives on today in relatively unmixed form in Sardinians and the people of the Basque Country, and in at least the Druze population in the Middle East. The other ancestral population is likely to have been the initial hunter-gathering population of Europe. These two populations were very different when they met. Today the hunter-gathering ancestral population of Europe appears to have its closest affinity to people in far Northeastern Siberia and Native Americans.
The statistical tools for analyzing population mixture were developed by Patterson and presented in a systematic way in the report. These tools are the same ones used in previous discoveries showing that Indian populations are admixed between two highly diverged ancestral populations and showing that Neanderthals contributed one to four percent of the ancestry of present-day Europeans. In addition, the paper releases a major new dataset that characterizes genetic diversity in 934 samples from 53 diverse worldwide populations.
"The human genome holds numerous secrets. Not only does it unlock important clues to cure human disease, it also reveal clues to our prehistoric past," said Mark Johnston, Editor-in-Chief of the journal GENETICS. "This relationship between humans separated by the Atlantic Ocean reveals surprising features of the migration patterns of our ancestors, and reinforces the truth that all humans are closely related."
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CITATION: Nick Patterson, Priya Moorjani, Yontao Luo, Swapan Mallick, Nadin Rohland, Yiping Zhan, Teri Genschoreck, Teresa Webster, and David Reich
Ancient Admixture in Human History
Genetics November 2012 Volume 192, pp 1065-1093
FUNDING: U.S. National Science Foundation HOMINID grant 1032255, and by National Institutes of Health grant GM100233.
ABOUT GENETICS: Since 1916, GENETICS (http://www.genetics.org/) has covered high quality, original research on a range of topics bearing on inheritance, including population and evolutionary genetics, complex traits, developmental and behavioral genetics, cellular genetics, gene expression, genome integrity and transmission, and genome and systems biology. GENETICS, a peer-reviewed, peer-edited journal of the Genetics Society of America is one of the world's most cited journals in genetics and heredity.
ABOUT GSA: Founded in 1931, the Genetics Society of America (GSA) is the professional membership organization for scientific researchers, educators, bioengineers, bioinformaticians and others interested in the field of genetics. Its nearly 5,000 members work to advance knowledge in the basic mechanisms of inheritance, from the molecular to the population level. The GSA is dedicated to promoting research in genetics and to facilitating communication among geneticists worldwide through its conferences, including the biennial conference on Model Organisms to Human Biology, an interdisciplinary meeting on current and cutting edge topics in genetics research, as well as annual and biennial meetings that focus on the genetics of particular organisms, including C. elegans, Drosophila, fungi, mice, yeast, and zebrafish. GSA publishes GENETICS, a leading journal in the field and an online, open-access journal, G3: Genes|Genomes|Genetics. For more information about GSA, please visit www.genetics-gsa.org. Also follow GSA on Facebook at facebook.com/GeneticsGSA and on Twitter @GeneticsGSA.
Native Americans and Northern Europeans more closely related than previously thought
Statistical tools used to show Neanderthals mixed with modern humans also show that Native Americans and Northern Europeans share a common ancestor, according to new research in the journal Genetics
2012-12-01
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[Press-News.org] Native Americans and Northern Europeans more closely related than previously thoughtStatistical tools used to show Neanderthals mixed with modern humans also show that Native Americans and Northern Europeans share a common ancestor, according to new research in the journal Genetics