Fish liver self-defense: How autophagy helps pufferfish survive under the cold and copper stress
By identifying and characterizing three key autophagy genes and tracking their responses under environmental stress, the study could help improve fish health management and support sustainable aquaculture. Human activities and climate deterioration are increasingly altering aquatic ecosystems, leading to frequent disease outbreaks and heavy economic losses in fish farming. Takifugu fasciatus is prized for its high nutritional value and medicinal compounds, including tetrodotoxin and collagen. However, the species is highly sensitive to copper contamination and cold stress. Copper concentrations in summer waters can reach levels harmful ...
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