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Science

Study gives first view of centromere variation and evolution

A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. In cell genetics, a centromere is the spot where two sister chromatids attach. A chromatid is one-half of a duplicated chromosome. United pairs of chromosomes have identifiable shapes because centromeres are not in a uniform position. As a cell prepares to divide, the machinery to separate and segregate chromosomes goes into action at each centromere location. Unless the genetic material ...

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Science

New study shows LLMs respond differently based on user’s motivation

A new study recently published in the Journal of the American Medical Informatics Association (JAMIA) reveals how large language models (LLMs) respond to different motivational states. In their evaluation of three LLM-based generative conversational agents (GAs)—ChatGPT, Google Bard, and Llama 2, PhD student Michelle Bak and Assistant Professor Jessie Chin of the School of Information Sciences at the University of Illinois Urbana-Champaign found that while GAs are able to identify users' ...

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Novel fabrication technique takes transition metal telluride nanosheets from lab to mass production
Science

Novel fabrication technique takes transition metal telluride nanosheets from lab to mass production

Transition metal telluride nanosheets have shown enormous promise for fundamental research and other applications across a rainbow of different fields, but until now, mass fabrication has been impossible, leaving the material as something of a laboratory curiosity rather than an industrial reality. But a team of researchers has recently developed a novel fabrication technique—the use of chemical solutions to peel off thin layers from their parent compounds, creating atomically thin sheets—that looks set to finally deliver on the ultra-thin substance's promise. The researchers describe their fabrication technique in a study published in Nature on April 3. In ...

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Two Jurassic mammaliaforms from China shed light on mammalian evolution
Science

Two Jurassic mammaliaforms from China shed light on mammalian evolution

Mammaliaforms are extinct and extant organisms that are closely related to mammals. Studying mammaliaforms helps scientists understand the evolutionary processes that led to various mammalian features. In two consecutive studies in Nature, Dr. MAO Fangyuan and Dr. ZHANG Chi from the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences, together with colleagues from Australia and the United States, recently reported two Jurassic mammaliaforms from China, revealing the earliest dental diversification, mandibular middle ears, and articular-quadrate joint transformation of mammaliaforms. The ...

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Intelligent liquid
Science

Intelligent liquid

Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a programmable metafluid with tunable springiness, optical properties, viscosity and even the ability to transition between a Newtonian and non-Newtonian fluid. The first-of-its-kind metafluid uses a suspension of small, elastomer spheres — between 50 to 500 microns — that buckle under pressure, radically changing the characteristics of the fluid. The metafluid could be used in everything ...

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Science

Jurassic shuotheriids reveal earliest dental diversification of mammaliaforms

Palaeontologists have presented a new insight into the initial dental variations across mammaliaforms, providing a fresh perspective on the evolutionary past of these ancient beasts. The discovery, involving a team of international researchers including Professor Patricia Vickers-Rich from the Monash University School of Earth, Atmosphere and Environment, is published today in the renowned journal Nature. The research, conducted by a group of palaeontologists from prestigious institutions in New York, China and Australia, examines the tooth structure of the Jurassic ...

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Tree of life for modern birds revealed
Science

Tree of life for modern birds revealed

2 April, 2024, Sydney; In a world first, a team of international scientists including three Australians, Al-Aabid Chowdhury and Professor Simon Ho from University of Sydney, and Dr Jacqueline Nguyen from Australian Museum and Flinders University, have determined the family tree of modern birds and pinpointed the timing of their evolution. Their findings have been published today in Nature. The largest study ever undertaken of modern bird genomes, the scientists combined genomic data of more than 360 bird species with data from nearly 200 bird fossils to reconstruct the most well-supported Tree of ...

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Science

Study finds gunshots in American cities twice as likely at night, potentially disrupting sleep for those in earshot

KEY TAKEAWAYS Researchers from Mass General Brigham analyzed timing and location of gunshots in six of the most populated U.S. cities (Baltimore, Boston, Washington, D.C., New York, Philadelphia, and Portland, Ore.) from 2015-2021. The team estimates that annually, approximately 12.5 million person-nights—the number of nights of gunshots multiplied by the number of people in earshot—are impacted by nighttime gunshots, and that those were more common in low-income areas in each city. The noise of nighttime gunshots may have underrecognized and underappreciated effects on ...

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Science

Water-based paints: Less stinky, but some still contain potentially hazardous chemicals

Choosing paint for your home brings a lot of options: What kind of paint, what type of finish and what color? Water-based paints have emerged as “greener” and less smelly than solvent-based options. And they are often advertised as containing little-to-no volatile organic compounds (VOCs). But, according to research published in ACS’ Environmental Science & Technology Letters, some of these paints do contain compounds that are considered VOCs, along with other chemicals of emerging concern. Paint consists of four ingredients: pigments, binders, additives ...

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Science

When tickling triggers more than just laughter

Scientists at the Institute of Pathophysiology of the University Medical Center Mainz made the first comprehensive analysis on how adults use tickling in connection with sexual activity. As part of their study, they surveyed 719 people with a so-called tickling fetish. The results of the study show that human sexuality encompasses a variety of forms of expression that need to be studied and understood in greater depth. Most people laugh when they are tickled. But there are also individuals for whom tickling or being tickled triggers sexual arousal. This sexual preference is referred to as a tickle ...

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Science

E-cigarette users now more likely to quit traditional cigarettes

A new paper in Nicotine & Tobacco Research, published by Oxford University Press, finds that smokers who switch to electronic cigarettes are now more likely to stop smoking regular cigarettes. In the past, smokers who began using electronic cigarettes mostly continued smoking. Electronic nicotine delivery systems first emerged on the U.S. market in 2007. The first e-cigarettes resembled conventional cigarettes (in appearance) and used fixed low-voltage batteries. Beginning in 2016, manufacturers introduced e-liquids containing nicotine salt formulations. These new e-cigarettes became widely available. These nicotine salts are lower in pH than freebase formulations, which allow manufacturers ...

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Science

Chatbot guides women through post-prison challenges

Most women leaving prison face profound disadvantages and rarely have access to the resources needed to settle back into the community. Seemingly simple tasks such as obtaining replacement identification documents or opening a bank account become tangled in complexities. Now researchers at the University of South Australia are co-designing a chatbot to help formerly incarcerated women re-establish their lives on the outside, and reduce the risk of them returning to prison. Led by a team of UniSA researchers in collaboration with advocacy group Seeds of Affinity, the tech-based solution aims to help women access trusted ...

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Galaxies get more chaotic as they age
Science

Galaxies get more chaotic as they age

Galaxies start life with their stars rotating in an orderly pattern but in some the motion of stars in more random. Until now, scientists have been uncertain about what causes this – possibly the surrounding environment or the mass of the galaxy itself. A new study, published in a paper today in MNRAS (Monthly Notices of the Royal Astronomical Society), has found that the most important factor is neither of these things. It shows the tendency of the stars to have random motion is driven mostly by the age of the galaxy – things just get messy over time. “When we did the analysis, we found that age, consistently, whichever way we slice or dice it, is always the most ...

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Science

Even moderate alcohol usage during pregnancy linked to birth abnormalities, UNM researchers find

University of New Mexico researchers have found that even low to moderate alcohol use by pregnant patients may contribute to subtle changes in their babies’ prenatal development, including lower birth length and a shorter duration of gestation. In a new paper published in the journal Alcohol Clinical & Experimental Research, a team led by Ludmila Bakhireva, MD, PhD, MPH, professor and assistant dean for Clinical and Translational Research in the UNM College of Pharmacy, also reported some sex-related differences in the effects of drinking during pregnancy on the developing ...

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Last chance to record archaic Greek language ‘heading for extinction’
Science

Last chance to record archaic Greek language ‘heading for extinction’

A new data crowdsourcing platform aims to preserve the sound of Romeyka, an endangered millennia-old variety of Greek. Experts consider the language to be a linguistic goldmine and a living bridge to the ancient world. The initiative, led by Professor Ioanna Sitaridou from the University of Cambridge, contributes to the UN’s International Decade of Indigenous Languages (2022-32), which aims ‘to draw global attention on the critical situation of many indigenous languages and to mobilise stakeholders and resources for their preservation, revitalization and promotion.’ Romeyka is thought to have only a couple of thousand ...

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Science

Chicks prove vision and touch linked at birth

Newly hatched chicks raised in darkness and allowed to touch either a smooth or bumpy cube for 24 hours instantly recognised the object with their vision upon first exposure to light. This suggests chicks can link touch and vision without any prior experience combining these senses, challenging the long-held belief that such integration requires learning. The discovery implies a pre-wired ability in the brain for cross-modal perception, potentially redefining our understanding of animal cognition and sensory processing. In a study published in Biology Letters, researchers at Queen Mary University of London have cracked ...

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Double trouble: the risks of mixing alcohol and sports wagering
Science

Double trouble: the risks of mixing alcohol and sports wagering

It turns out that money isn’t the only thing sports gamblers are risking. According to a new study, bettors who wager on sporting events, esports, and daily fantasy sports are much more likely than other individuals to binge drink. The findings, compiled by a research team from UNLV and the University of New Mexico, were published this week in the journal JAMA Network Open. Over the course of three weeks in spring 2022, researchers surveyed more than 4,300 adults across the U.S. Nearly 3,300 self-reported past year alcohol use, while about 1,800 identified themselves as gamblers who had bet on sports in the past year. Researchers ...

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Sunrise to sunset, new window coating blocks heat — not view
Science

Sunrise to sunset, new window coating blocks heat — not view

Windows welcome light into interior spaces, but they also bring in unwanted heat. A new window coating blocks heat-generating ultraviolet and infrared light and lets through visible light, regardless of the sun’s angle. The coating can be incorporated onto existing windows or automobiles and can reduce air-conditioning cooling costs by more than one-third in hot climates. “The angle between the sunshine and your window is always changing,” said Tengfei Luo, the Dorini Family Professor for Energy Studies at the University of Notre ...

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Science

Study finds Netflix misses the mark by trivializing teenagers’ pain

UCalgary led study finds Netflix misses the mark by trivializing teenagers’ pain. Findings are published in PainResearchers at the University of Calgary and the University of Bath, U.K., are calling on Netflix to do a better job of representing the kind of pain typically experienced by 12-to-18-year-olds. A new study finds the streaming channel should not emphasize stereotypes, like the heroic, stoic boy and the helpless, emotional girl who requires his rescue and prioritizes his pain and suffering. “Media ...

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Methods sections often lack critical details needed to reproduce an experiment, and the practice of citing previous papers instead of describing the methods in detail may contribute to this problem
Science

Methods sections often lack critical details needed to reproduce an experiment, and the practice of citing previous papers instead of describing the methods in detail may contribute to this problem

Methods sections often lack critical details needed to reproduce an experiment, and the practice of citing previous papers instead of describing the methods in detail may contribute to this problem Analysis of >750 papers shows that >90% of papers use at least one shortcut citation, that these significantly impair reconstruction of the original method, and that

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Morris Animal Foundation-funded researchers develop early osteoarthritis detection tool
Science

Morris Animal Foundation-funded researchers develop early osteoarthritis detection tool

Media Alert: DENVER/April 2, 2024 — Morris Animal Foundation-funded researchers introduced a straightforward questionnaire to help horse owners identify and monitor signs of osteoarthritis pain in their equine companions. This initiative aims to facilitate earlier and more effective treatment, ultimately enhancing the quality of life for horses. Created by Dr. Janny de Grauw, Senior Lecturer at The Royal Veterinary College in the United Kingdom, Bryony Lancaster, Program Director, MSc Equine Science of the University of Edinburgh and Dr. Diane Howard, the questionnaire is modeled after the Brief Pain Inventory used to evaluate pain severity and its impact ...

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These plants evolved in Florida millions of years ago. They may be gone in decades.
Science

These plants evolved in Florida millions of years ago. They may be gone in decades.

Scrub mints are among the most endangered plants you’ve probably never heard of. More than half of the 24 species currently known to exist are considered threatened or endangered at the state or federal level, and nearly all scrub mints grow in areas that are being rapidly developed or converted to agricultural pasture. In a new study, researchers analyzed a distinct type of DNA marker, which shows there are likely more scrub mint species waiting to be scientifically described. And at least one species has been left without federal protection because of a technicality. “The Titusville balm is currently considered ...

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Science

All-cash home buyers pay 10% less than mortgage buyers

Owning a home has long been considered a crucial way to build wealth, but making such a purchase has become increasingly difficult for many residents. In addition to steep housing prices and high interest rates, there have been a growing number of all-cash buyers who can close a deal quickly, beating out competing offers from buyers who need to finance their home with a mortgage. The convenience and certainty of all-cash offers appeals to sellers so much so, that they pay on average 10 % less than mortgage buyers, according to a new study from the University of California San Diego Rady School of Management. “When sellers accept a mortgage offer, it comes with risk,” said Michael ...

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Science

Surveillance colonoscopy findings in older adults with a history of colorectal adenomas

About The Study: In this study of 9,740 surveillance colonoscopies among 9,601 adults ages 70 to 85 with prior colorectal adenoma, colorectal cancer detection was rare regardless of prior adenoma finding, whereas the advanced neoplasia yield was 12% overall. Yields were higher among those with a prior advanced adenoma than among those with prior nonadvanced adenoma and did not increase significantly with age. These findings can help inform whether to continue surveillance colonoscopy in older adults. Authors: Jeffrey K. Lee, M.D., M.P.H., of Kaiser Permanente Northern California in Oakland, is the corresponding author. To access the embargoed study: ...

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Science

Metabolic profile and long-term risk of depression, anxiety, and stress-related disorders

About The Study: High levels of glucose and triglycerides and low levels of high-density lipoprotein were associated with future risk of depression, anxiety, and stress-related disorders in this study of more than 200,000 participants. These findings may support closer follow-up of individuals with metabolic dysregulations for the prevention and diagnosis of psychiatric disorders. Authors: Charilaos Chourpiliadis, M.D., of the Karolinska Institutet in Stockholm, is the corresponding ...

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